UA68332C2 - Moraxeila catarrhalis outer membrane protein-106 (omp106) polypeptide, peptide fragment and encoding nucleotide sequences, antibodies binding omp106 polypeptide, vaccine and antigenic composition (variants), methods of inducing immune responses to m. catarrhalis in animals (variants), method for treatment and prevention of m. catarrhalis infection (variants) - Google Patents

Moraxeila catarrhalis outer membrane protein-106 (omp106) polypeptide, peptide fragment and encoding nucleotide sequences, antibodies binding omp106 polypeptide, vaccine and antigenic composition (variants), methods of inducing immune responses to m. catarrhalis in animals (variants), method for treatment and prevention of m. catarrhalis infection (variants) Download PDF

Info

Publication number
UA68332C2
UA68332C2 UA98126370A UA98126370A UA68332C2 UA 68332 C2 UA68332 C2 UA 68332C2 UA 98126370 A UA98126370 A UA 98126370A UA 98126370 A UA98126370 A UA 98126370A UA 68332 C2 UA68332 C2 UA 68332C2
Authority
UA
Ukraine
Prior art keywords
polypeptide
omp106
sequence
catarrhalis
variants
Prior art date
Application number
UA98126370A
Other languages
English (en)
Ukrainian (uk)
Original Assignee
Antex Biolog Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Antex Biolog Inc filed Critical Antex Biolog Inc
Publication of UA68332C2 publication Critical patent/UA68332C2/uk

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/21—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Pseudomonadaceae (F)
    • C07K14/212—Moraxellaceae, e.g. Acinetobacter, Moraxella, Oligella, Psychrobacter
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1203—Gram-negative bacteria
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1203—Gram-negative bacteria
    • C07K16/1214—Pseudomonadaceae (F)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1203—Gram-negative bacteria
    • C07K16/1217—Neisseriaceae (F)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73—Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C07K2317/734—Complement-dependent cytotoxicity [CDC]
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
UA98126370A 1996-05-03 1997-04-28 Moraxeila catarrhalis outer membrane protein-106 (omp106) polypeptide, peptide fragment and encoding nucleotide sequences, antibodies binding omp106 polypeptide, vaccine and antigenic composition (variants), methods of inducing immune responses to m. catarrhalis in animals (variants), method for treatment and prevention of m. catarrhalis infection (variants) UA68332C2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/642,712 US7341727B1 (en) 1996-05-03 1996-05-03 M. catarrhalis outer membrane protein-106 polypeptide, methods of eliciting an immune response comprising same
PCT/US1997/007679 WO1997041731A1 (en) 1996-05-03 1997-04-28 Moraxella catarrhalis outer membrane protein-106 polypeptide, gene sequence and uses thereof

Publications (1)

Publication Number Publication Date
UA68332C2 true UA68332C2 (en) 2004-08-16

Family

ID=24577687

Family Applications (1)

Application Number Title Priority Date Filing Date
UA98126370A UA68332C2 (en) 1996-05-03 1997-04-28 Moraxeila catarrhalis outer membrane protein-106 (omp106) polypeptide, peptide fragment and encoding nucleotide sequences, antibodies binding omp106 polypeptide, vaccine and antigenic composition (variants), methods of inducing immune responses to m. catarrhalis in animals (variants), method for treatment and prevention of m. catarrhalis infection (variants)

Country Status (25)

Country Link
US (6) US7341727B1 (enExample)
EP (1) EP0900025B1 (enExample)
JP (2) JP4401437B2 (enExample)
CN (2) CN1222618C (enExample)
AR (1) AR006999A1 (enExample)
AT (1) ATE244016T1 (enExample)
AU (1) AU723528B2 (enExample)
BG (1) BG64832B1 (enExample)
BR (1) BR9711090A (enExample)
CA (1) CA2253636C (enExample)
CZ (1) CZ298034B6 (enExample)
DE (1) DE69723254T2 (enExample)
EA (1) EA002743B1 (enExample)
EE (1) EE04684B1 (enExample)
ES (1) ES2202624T3 (enExample)
GE (1) GEP20022695B (enExample)
HU (1) HU223004B1 (enExample)
NO (2) NO324816B1 (enExample)
NZ (1) NZ332896A (enExample)
PL (3) PL189995B1 (enExample)
SK (1) SK284812B6 (enExample)
TW (1) TW541314B (enExample)
UA (1) UA68332C2 (enExample)
WO (1) WO1997041731A1 (enExample)
ZA (1) ZA973809B (enExample)

Families Citing this family (71)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6440425B1 (en) * 1995-05-01 2002-08-27 Aventis Pasteur Limited High molecular weight major outer membrane protein of moraxella
US6335018B1 (en) * 1995-05-01 2002-01-01 Aventis Pasteur Limited High molecular weight major outer membrane protein of moraxella
US7341727B1 (en) * 1996-05-03 2008-03-11 Emergent Product Development Gaithersburg Inc. M. catarrhalis outer membrane protein-106 polypeptide, methods of eliciting an immune response comprising same
AUPO652897A0 (en) 1997-04-30 1997-05-29 University Of Melbourne, The Synthetic peptide constructs for the diagnosis and treatment of periodontitis
GB9714276D0 (en) * 1997-07-08 1997-09-10 Univ Dundee Peptides and related compounds
US8129500B2 (en) 1997-12-10 2012-03-06 Csl Limited Porphyromonas gingivalis polypeptides and nucleotides
GB9808720D0 (en) * 1998-04-23 1998-06-24 Smithkline Beecham Biolog Novel compounds
GB9810084D0 (en) 1998-05-11 1998-07-08 Cortecs Uk Ltd Proteins
US6627728B1 (en) 1998-05-12 2003-09-30 Smithkline Beecham Biologicals S.A. Compounds from moraxella catarrhalis
GB9810193D0 (en) * 1998-05-12 1998-07-08 Smithkline Beecham Biolog Novel compounds
GB9810285D0 (en) 1998-05-13 1998-07-15 Smithkline Beecham Biolog Novel compounds
US6541616B1 (en) * 1998-10-01 2003-04-01 Antex Biologics Inc. Moraxella catarrhalis protein, gene sequence and uses thereof
CA2366152A1 (en) 1999-03-19 2000-09-28 Smithkline Beecham Biologicals S.A. Streptococcus pneumoniae vaccine
US6673910B1 (en) 1999-04-08 2004-01-06 Genome Therapeutics Corporation Nucleic acid and amino acid sequences relating to M. catarrhalis for diagnostics and therapeutics
ES2306662T3 (es) * 1999-05-24 2008-11-16 Glaxosmithkline Biologicals S.A. Nuevos compuestos de moraxella catarrhalis.
GB9915031D0 (en) * 1999-06-25 1999-08-25 Smithkline Beecham Biolog Novel compounds
GB9921691D0 (en) * 1999-09-14 1999-11-17 Smithkline Beecham Sa Novel compounds
WO2001019862A2 (en) * 1999-09-14 2001-03-22 Smithkline Beecham Biologicals S.A. Polypeptides from moraxella (branhamella) catarrhalis
GB0022742D0 (en) 2000-09-15 2000-11-01 Smithkline Beecham Biolog Vaccine
GB0103171D0 (en) 2001-02-08 2001-03-28 Smithkline Beecham Biolog Vaccine composition
SE0102410D0 (sv) * 2001-07-04 2001-07-04 Arne Forsgren Novel surface exposed immunoglobulin D-binding protein from moraxella catarrhalis
CN1674933B (zh) 2002-08-02 2012-09-26 葛兰素史密丝克莱恩生物有限公司 疫苗组合物
IL308456A (en) 2005-04-08 2024-01-01 Wyeth Llc A multivalent pneumomuroral protein-polysaccharide conjugate preparation
CN100357318C (zh) * 2005-10-11 2007-12-26 中山大学 美人鱼发光杆菌外膜蛋白w和编码序列及其制备方法和应用
TWI457133B (zh) 2005-12-13 2014-10-21 Glaxosmithkline Biolog Sa 新穎組合物
GB0607088D0 (en) 2006-04-07 2006-05-17 Glaxosmithkline Biolog Sa Vaccine
JP5792920B2 (ja) 2005-12-22 2015-10-14 グラクソスミスクライン バイオロジカルズ ソシエテ アノニム ワクチン
MX2008009280A (es) 2006-01-17 2008-12-12 Arne Forsgren Una nueva proteina de haemophilus influenzae expuesta en la superficie (proteina e; pe).
CA2652957A1 (en) 2006-06-27 2008-01-03 Oral Health Australia Pty Ltd. Porphyromonas gingivalis polypeptides useful in the prevention of periodontal disease
EA200901578A1 (ru) 2007-06-26 2010-08-30 Глаксосмитклайн Байолоджикалс С.А. Вакцина, содержащая конъюгаты капсульных полисахаридов streptococcus pneumoniae
EP2638905B1 (en) 2007-07-12 2019-01-16 Oral Health Australia Pty Ltd Biofilm treatment
CN102652831A (zh) 2007-07-12 2012-09-05 口腔健康澳洲私人有限公司 生物膜的免疫治疗
WO2009049013A2 (en) * 2007-10-09 2009-04-16 Tufts University Cholera vaccines
EP2328914B1 (en) 2008-08-29 2017-05-10 Oral Health Australia Pty Ltd Prevention, treatment and diagnosis of p.gingivalis infection
US8140041B2 (en) * 2009-08-27 2012-03-20 Mediatek Inc. Tunable capacitive device with linearization technique employed therein
ES2366735B1 (es) * 2009-10-08 2012-09-13 Fundación Pública Andaluza Para La Gestión De La Investigación En Salud De Sevilla Vacuna frente a acinetobacter baumannii.
WO2011063408A1 (en) 2009-11-23 2011-05-26 Cyvek, Inc. Method and apparatus for performing assays
US9700889B2 (en) 2009-11-23 2017-07-11 Cyvek, Inc. Methods and systems for manufacture of microarray assay systems, conducting microfluidic assays, and monitoring and scanning to obtain microfluidic assay results
US9500645B2 (en) 2009-11-23 2016-11-22 Cyvek, Inc. Micro-tube particles for microfluidic assays and methods of manufacture
US9759718B2 (en) 2009-11-23 2017-09-12 Cyvek, Inc. PDMS membrane-confined nucleic acid and antibody/antigen-functionalized microlength tube capture elements, and systems employing them, and methods of their use
US9855735B2 (en) 2009-11-23 2018-01-02 Cyvek, Inc. Portable microfluidic assay devices and methods of manufacture and use
US10065403B2 (en) 2009-11-23 2018-09-04 Cyvek, Inc. Microfluidic assay assemblies and methods of manufacture
US9651568B2 (en) 2009-11-23 2017-05-16 Cyvek, Inc. Methods and systems for epi-fluorescent monitoring and scanning for microfluidic assays
GB201003922D0 (en) 2010-03-09 2010-04-21 Glaxosmithkline Biolog Sa Conjugation process
GB201003924D0 (en) 2010-03-09 2010-04-21 Glaxosmithkline Biolog Sa Immunogenic composition
EP2544714A1 (en) 2010-03-10 2013-01-16 GlaxoSmithKline Biologicals S.A. Vaccine composition
JP6002659B2 (ja) 2010-04-13 2016-10-05 セルデックス・セラピューティクス・インコーポレイテッド ヒトｃｄ２７に結合する抗体およびその使用
WO2011137334A1 (en) * 2010-04-30 2011-11-03 The Research Foundation Of State University Of New York Compositions and methods for stimulating immune response against moraxella catarrhalis
GB201103836D0 (en) 2011-03-07 2011-04-20 Glaxosmithkline Biolog Sa Conjugation process
JP5978287B2 (ja) 2011-03-22 2016-08-24 サイヴェク・インコーポレイテッド マイクロ流体装置並びに製造及び使用の方法
RU2481401C2 (ru) * 2011-07-15 2013-05-10 Государственное образовательное учреждение высшего профессионального образования "Уральская государственная медицинская академия Министерства здравоохранения и социального развития Российской Федерации" (ГОУ ВПО УГМА Минздравсоцразвития России) СПОСОБ ВЫЯВЛЕНИЯ β-ЛАКТАМАЗОПРОДУЦИРУЮЩИХ ОКСИДАЗОПОЗИТИВНЫХ ГРАМОТРИЦАТЕЛЬНЫХ ДИПЛОКОККОВ, ПОДОЗРИТЕЛЬНЫХ НА ПРИНАДЛЕЖНОСТЬ К MORAХELLA (BRANCHAMELLA) CATARRHALIS
EP2822688B1 (en) 2012-03-08 2019-09-25 Cyvek, Inc. Microfluidic assay assemblies and methods of manufacture
US11210432B2 (en) * 2013-08-20 2021-12-28 Janus Technologies, Inc. Method and apparatus for selectively snooping and capturing data for secure computer interfaces
WO2016145085A2 (en) 2015-03-09 2016-09-15 Celldex Therapeutics, Inc. Cd27 agonists
GB201518684D0 (en) 2015-10-21 2015-12-02 Glaxosmithkline Biolog Sa Vaccine
US10228367B2 (en) 2015-12-01 2019-03-12 ProteinSimple Segmented multi-use automated assay cartridge
BR112018071307A2 (pt) 2016-04-18 2019-02-26 Celldex Therapeutics, Inc. anticorpos agonistas que ligam cd40 humana e usos dos mesmos
GB201621686D0 (en) 2016-12-20 2017-02-01 Glaxosmithkline Biologicals Sa Novel methods for inducing an immune response
GB2600652B (en) 2017-05-30 2022-11-02 Glaxosmithkline Biologicals Sa Novel compositions
JP2021504424A (ja) 2017-12-01 2021-02-15 グラクソスミスクライン バイオロジカルズ ソシエテ アノニム サポニン精製
KR20210011919A (ko) 2018-04-17 2021-02-02 셀덱스 쎄라퓨틱스, 인크. 항-cd27 항체 및 항-pd-l1 항체 및 이중특이적 작제물
BR112021000965A2 (pt) 2018-08-07 2021-04-27 Glaxosmithkline Biologicals S.A. processos e vacinas
CN111157735B (zh) * 2018-11-07 2023-02-07 广州万孚生物技术股份有限公司 凝集性卡他莫拉菌单克隆抗体及其制备方法和应用
EP3886901A1 (en) 2018-11-29 2021-10-06 GlaxoSmithKline Biologicals S.A. Methods for manufacturing an adjuvant
US20220016168A1 (en) 2018-12-11 2022-01-20 Celldex Therapeutics, Inc. Methods of using cd27 antibodies as conditioning treatment for adoptive cell therapy
WO2020245207A1 (en) 2019-06-05 2020-12-10 Glaxosmithkline Biologicals Sa Saponin purification
CN111778226B (zh) * 2020-07-21 2022-04-05 东北师范大学 一种水稻耐碱胁迫相关的质膜H+-ATPase蛋白及其应用
CN117545773A (zh) 2021-04-09 2024-02-09 塞德斯医疗公司 抗ilt4的抗体、双特异性抗ilt4/pd-l1抗体及其用途
WO2023077521A1 (en) 2021-11-08 2023-05-11 Celldex Therapeutics, Inc Anti-ilt4 and anti-pd-1 bispecific constructs
GB202205833D0 (en) 2022-04-21 2022-06-08 Glaxosmithkline Biologicals Sa Bacteriophage
WO2024017827A1 (en) 2022-07-19 2024-01-25 Glaxosmithkline Biologicals Sa Continuous process for vaccine production

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4675176A (en) * 1983-12-12 1987-06-23 Norden Laboratories Moraxella bovis protease vaccine
US4879213A (en) * 1986-12-05 1989-11-07 Scripps Clinic And Research Foundation Synthetic polypeptides and antibodies related to Epstein-Barr virus early antigen-diffuse
US5552146A (en) * 1991-08-15 1996-09-03 Board Of Regents, The University Of Texas System Methods and compositions relating to useful antigens of Moraxella catarrhalis
US5607846A (en) 1994-05-17 1997-03-04 Research Foundation Of State University Of New York Vaccine for moraxella catarrhalis
US6335018B1 (en) * 1995-05-01 2002-01-01 Aventis Pasteur Limited High molecular weight major outer membrane protein of moraxella
US6440425B1 (en) 1995-05-01 2002-08-27 Aventis Pasteur Limited High molecular weight major outer membrane protein of moraxella
US7341727B1 (en) * 1996-05-03 2008-03-11 Emergent Product Development Gaithersburg Inc. M. catarrhalis outer membrane protein-106 polypeptide, methods of eliciting an immune response comprising same
GB9809683D0 (en) 1998-05-06 1998-07-01 Smithkline Beecham Biolog Novel compounds
GB9812163D0 (en) 1998-06-05 1998-08-05 Smithkline Beecham Biolog Novel compounds

Also Published As

Publication number Publication date
CN1800359A (zh) 2006-07-12
NO985113D0 (no) 1998-11-02
SK284812B6 (sk) 2005-12-01
US7128910B2 (en) 2006-10-31
AU3118097A (en) 1997-11-26
WO1997041731A1 (en) 1997-11-13
CN1223549A (zh) 1999-07-21
EP0900025A4 (en) 2000-01-05
DE69723254T2 (de) 2004-04-22
JP4401437B2 (ja) 2010-01-20
CA2253636A1 (en) 1997-11-13
ZA973809B (en) 1997-12-01
US20100021492A1 (en) 2010-01-28
GEP20022695B (en) 2002-05-27
JP2008161194A (ja) 2008-07-17
DE69723254D1 (de) 2003-08-07
HU223004B1 (hu) 2004-03-01
US20070087019A1 (en) 2007-04-19
HUP9902695A2 (hu) 1999-12-28
HK1095358A1 (zh) 2007-05-04
HUP9902695A3 (en) 2001-02-28
CZ352498A3 (cs) 1999-06-16
PL189375B1 (pl) 2005-07-29
NO324816B1 (no) 2007-12-10
PL189374B1 (pl) 2005-07-29
US20080145916A1 (en) 2008-06-19
AU723528B2 (en) 2000-08-31
CN1222618C (zh) 2005-10-12
EP0900025A1 (en) 1999-03-10
PL189995B1 (pl) 2005-10-31
NZ332896A (en) 2000-05-26
PL330935A1 (en) 1999-06-07
CZ298034B6 (cs) 2007-05-30
US6214981B1 (en) 2001-04-10
CN100415871C (zh) 2008-09-03
EA199800973A1 (ru) 1999-06-24
ATE244016T1 (de) 2003-07-15
EE9800373A (et) 1999-04-15
BG64832B1 (bg) 2006-06-30
US7576179B2 (en) 2009-08-18
ES2202624T3 (es) 2004-04-01
US7914795B2 (en) 2011-03-29
EA002743B1 (ru) 2002-08-29
NO985113L (no) 1998-12-28
TW541314B (en) 2003-07-11
BR9711090A (pt) 1999-08-17
US20020177200A1 (en) 2002-11-28
EE04684B1 (et) 2006-08-15
AR006999A1 (es) 1999-10-13
JP2000510696A (ja) 2000-08-22
EP0900025B1 (en) 2003-07-02
BG102983A (en) 2000-05-31
US7341727B1 (en) 2008-03-11
HK1021299A1 (en) 2000-06-09
NO20063711L (no) 1998-12-28
CA2253636C (en) 2003-04-22
SK150998A3 (en) 1999-05-07

Similar Documents

Publication Publication Date Title
EA002743B1 (ru) Полипептид белка-106 наружной мембраны moraxella catarrhalis, днк, его кодирующие, и их применение
EA007409B1 (ru) Антигенные полипептиды стрептококков, способы их получения и применения
KR19980703099A (ko) 프로테이나제 ｋ에 대해 내성을 갖는 네이쎄리아 메닝기티디스의 표면 단백질
AU614718B2 (en) A neisseria gonorrhoeae lectin useful as a vaccine and diagnostic marker and means for producing this lectin
US10603373B2 (en) Targets of Acinetobacter baumannii
RU2252224C2 (ru) Пептид со свойствами антигена neisseria meningitidis, кодирующий его полинуклеотид, вакцина для лечения или предотвращения заболеваний или состояний, вызванных neisseria meningitidis, (варианты), антитело, связывающееся с указанным пептидом
CN116063548B (zh) 一种融合蛋白KP-Ag1及其用作肺炎克雷伯菌疫苗抗原的应用
WO1993000358A1 (en) Pseudomonas exoenzyme s peptide composition and method
JP3124753B2 (ja) インフルエンザ菌用ワクチンおよび診断法
US7311917B2 (en) Moraxella catarrhalis protein, gene sequence and uses thereof
KR100366482B1 (ko) 백신으로서 정제된 분류가능하지 않은 헤모필루스 인프루엔자 p5단백질, 및 그의 정제방법
CA2520386A1 (en) Nontypeable haemophilus influenzae virulence factors
KR20010044842A (ko) 백신 보조제로서 콜레라 독소 비 또는 장독소 비의펩타이드 단편
CA2328130A1 (en) Moraxella catarrhalis proteins
US6218147B1 (en) Haemophilus adhesin protein
KR100500000B1 (ko) 모락셀라카타르할리스외측막단백질-16폴리펩티드,이의유전자서열및이의용도
CA2182046A1 (en) Haemophilus adhesin protein
CN100387718C (zh) 抗蛋白酶k降解的脑膜炎奈瑟氏球菌表面蛋白
HK1095358B (en) Moraxella catarrhalis outer membrane protein-106 polypeptide, gene sequence and use thereof
CN119185523A (zh) 预防b群脑膜炎球菌感染的广谱多联亚单位疫苗及其用途
WO2004104044A1 (ja) 抗体の製造方法