TW541314B - Moraxella catarrhalis outer membrane protein-106 polypeptide, gene sequence and uses thereof - Google Patents

Moraxella catarrhalis outer membrane protein-106 polypeptide, gene sequence and uses thereof Download PDF

Info

Publication number
TW541314B
TW541314B TW086105809A TW86105809A TW541314B TW 541314 B TW541314 B TW 541314B TW 086105809 A TW086105809 A TW 086105809A TW 86105809 A TW86105809 A TW 86105809A TW 541314 B TW541314 B TW 541314B
Authority
TW
Taiwan
Prior art keywords
omp
polypeptide
atcc
moraxella catarrhalis
sequence
Prior art date
Application number
TW086105809A
Other languages
English (en)
Chinese (zh)
Inventor
Kenneth Tucker
Laura Plosila
Original Assignee
Antex Biolog Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Antex Biolog Inc filed Critical Antex Biolog Inc
Application granted granted Critical
Publication of TW541314B publication Critical patent/TW541314B/zh

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/21Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Pseudomonadaceae (F)
    • C07K14/212Moraxellaceae, e.g. Acinetobacter, Moraxella, Oligella, Psychrobacter
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1203Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1203Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria
    • C07K16/1214Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria from Pseudomonadaceae (F)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1203Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria
    • C07K16/1217Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria from Neisseriaceae (F)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/73Inducing cell death, e.g. apoptosis, necrosis or inhibition of cell proliferation
    • C07K2317/734Complement-dependent cytotoxicity [CDC]
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
TW086105809A 1996-05-03 1997-05-01 Moraxella catarrhalis outer membrane protein-106 polypeptide, gene sequence and uses thereof TW541314B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/642,712 US7341727B1 (en) 1996-05-03 1996-05-03 M. catarrhalis outer membrane protein-106 polypeptide, methods of eliciting an immune response comprising same

Publications (1)

Publication Number Publication Date
TW541314B true TW541314B (en) 2003-07-11

Family

ID=24577687

Family Applications (1)

Application Number Title Priority Date Filing Date
TW086105809A TW541314B (en) 1996-05-03 1997-05-01 Moraxella catarrhalis outer membrane protein-106 polypeptide, gene sequence and uses thereof

Country Status (25)

Country Link
US (6) US7341727B1 (enExample)
EP (1) EP0900025B1 (enExample)
JP (2) JP4401437B2 (enExample)
CN (2) CN1222618C (enExample)
AR (1) AR006999A1 (enExample)
AT (1) ATE244016T1 (enExample)
AU (1) AU723528B2 (enExample)
BG (1) BG64832B1 (enExample)
BR (1) BR9711090A (enExample)
CA (1) CA2253636C (enExample)
CZ (1) CZ298034B6 (enExample)
DE (1) DE69723254T2 (enExample)
EA (1) EA002743B1 (enExample)
EE (1) EE04684B1 (enExample)
ES (1) ES2202624T3 (enExample)
GE (1) GEP20022695B (enExample)
HU (1) HU223004B1 (enExample)
NO (2) NO324816B1 (enExample)
NZ (1) NZ332896A (enExample)
PL (3) PL189995B1 (enExample)
SK (1) SK284812B6 (enExample)
TW (1) TW541314B (enExample)
UA (1) UA68332C2 (enExample)
WO (1) WO1997041731A1 (enExample)
ZA (1) ZA973809B (enExample)

Families Citing this family (71)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6335018B1 (en) * 1995-05-01 2002-01-01 Aventis Pasteur Limited High molecular weight major outer membrane protein of moraxella
US6440425B1 (en) * 1995-05-01 2002-08-27 Aventis Pasteur Limited High molecular weight major outer membrane protein of moraxella
US7341727B1 (en) * 1996-05-03 2008-03-11 Emergent Product Development Gaithersburg Inc. M. catarrhalis outer membrane protein-106 polypeptide, methods of eliciting an immune response comprising same
AUPO652897A0 (en) 1997-04-30 1997-05-29 University Of Melbourne, The Synthetic peptide constructs for the diagnosis and treatment of periodontitis
GB9714276D0 (en) * 1997-07-08 1997-09-10 Univ Dundee Peptides and related compounds
US8129500B2 (en) * 1997-12-10 2012-03-06 Csl Limited Porphyromonas gingivalis polypeptides and nucleotides
GB9808720D0 (en) 1998-04-23 1998-06-24 Smithkline Beecham Biolog Novel compounds
GB9810084D0 (en) 1998-05-11 1998-07-08 Cortecs Uk Ltd Proteins
WO1999058682A2 (en) * 1998-05-12 1999-11-18 Smithkline Beecham Biologicals S.A. Compounds from moraxella catarrhalis
GB9810193D0 (en) * 1998-05-12 1998-07-08 Smithkline Beecham Biolog Novel compounds
GB9810285D0 (en) * 1998-05-13 1998-07-15 Smithkline Beecham Biolog Novel compounds
US6541616B1 (en) * 1998-10-01 2003-04-01 Antex Biologics Inc. Moraxella catarrhalis protein, gene sequence and uses thereof
DE60043930D1 (de) 1999-03-19 2010-04-15 Glaxosmithkline Biolog Sa Impfstoff gegen kapsulare polysaccharide von streptococcus pneumoniae
US6673910B1 (en) 1999-04-08 2004-01-06 Genome Therapeutics Corporation Nucleic acid and amino acid sequences relating to M. catarrhalis for diagnostics and therapeutics
AU4567300A (en) * 1999-05-24 2000-12-12 Smithkline Beecham Biologicals (Sa) Novel compounds
GB9915031D0 (en) * 1999-06-25 1999-08-25 Smithkline Beecham Biolog Novel compounds
GB9921691D0 (en) * 1999-09-14 1999-11-17 Smithkline Beecham Sa Novel compounds
AU1383901A (en) * 1999-09-14 2001-04-17 Smithkline Beecham Biologicals (Sa) Novel compounds
GB0022742D0 (en) 2000-09-15 2000-11-01 Smithkline Beecham Biolog Vaccine
GB0103171D0 (en) 2001-02-08 2001-03-28 Smithkline Beecham Biolog Vaccine composition
SE0102410D0 (sv) * 2001-07-04 2001-07-04 Arne Forsgren Novel surface exposed immunoglobulin D-binding protein from moraxella catarrhalis
PT1524993E (pt) 2002-08-02 2013-06-12 Glaxosmithkline Biolog Sa Composições de vacina de neisseria compreendendo uma combinação de antigénios
CN104815327A (zh) 2005-04-08 2015-08-05 惠氏有限责任公司 多价肺炎球菌多糖-蛋白质缀合物组合物
CN100357318C (zh) * 2005-10-11 2007-12-26 中山大学 美人鱼发光杆菌外膜蛋白w和编码序列及其制备方法和应用
TWI457133B (zh) 2005-12-13 2014-10-21 Glaxosmithkline Biolog Sa 新穎組合物
GB0607088D0 (en) 2006-04-07 2006-05-17 Glaxosmithkline Biolog Sa Vaccine
MX2008008140A (es) 2005-12-22 2008-09-24 Glaxosmithkline Biolog Sa Vacuna que comprende conjugados de polisacarido capsular de streptococcus pneumonia.
EA015561B1 (ru) 2006-01-17 2011-08-30 Арне Форсгрен НОВЫЙ ПОВЕРХНОСТНЫЙ БЕЛОК HAEMOPHILUS INFLUENZAE (БЕЛОК E; pE)
US20100092471A1 (en) * 2006-06-27 2010-04-15 Oral Health Australia Pty Ltd Porphyromonas Gingivalis Polypeptides Useful in the Prevention of Periodontal Disease
US9610339B2 (en) 2007-06-26 2017-04-04 Glaxosmithkline Biologicals, S.A. Vaccine comprising Streptococcus pneumoniae capsular polysaccharide conjugates
NZ605037A (en) 2007-07-12 2014-05-30 Oral Health Australia Pty Ltd Immunology treatment for biofilms
NZ595252A (en) 2007-07-12 2013-11-29 Oral Health Australia Pty Ltd Biofilm treatment
WO2009049013A2 (en) * 2007-10-09 2009-04-16 Tufts University Cholera vaccines
DK2328914T3 (en) 2008-08-29 2017-07-10 Oral Health Australia Pty Ltd Prevention, treatment and diagnosis of P. gingivalis infection
US8140041B2 (en) * 2009-08-27 2012-03-20 Mediatek Inc. Tunable capacitive device with linearization technique employed therein
ES2366735B1 (es) * 2009-10-08 2012-09-13 Fundación Pública Andaluza Para La Gestión De La Investigación En Salud De Sevilla Vacuna frente a acinetobacter baumannii.
US9855735B2 (en) 2009-11-23 2018-01-02 Cyvek, Inc. Portable microfluidic assay devices and methods of manufacture and use
US9759718B2 (en) 2009-11-23 2017-09-12 Cyvek, Inc. PDMS membrane-confined nucleic acid and antibody/antigen-functionalized microlength tube capture elements, and systems employing them, and methods of their use
US9500645B2 (en) 2009-11-23 2016-11-22 Cyvek, Inc. Micro-tube particles for microfluidic assays and methods of manufacture
US9216412B2 (en) 2009-11-23 2015-12-22 Cyvek, Inc. Microfluidic devices and methods of manufacture and use
WO2013133899A1 (en) 2012-03-08 2013-09-12 Cyvek, Inc Microfluidic assay systems employing micro-particles and methods of manufacture
US10022696B2 (en) 2009-11-23 2018-07-17 Cyvek, Inc. Microfluidic assay systems employing micro-particles and methods of manufacture
US10065403B2 (en) 2009-11-23 2018-09-04 Cyvek, Inc. Microfluidic assay assemblies and methods of manufacture
US9700889B2 (en) 2009-11-23 2017-07-11 Cyvek, Inc. Methods and systems for manufacture of microarray assay systems, conducting microfluidic assays, and monitoring and scanning to obtain microfluidic assay results
CN102713621B (zh) 2009-11-23 2016-10-19 西维克公司 用于施行化验的方法和设备
GB201003924D0 (en) 2010-03-09 2010-04-21 Glaxosmithkline Biolog Sa Immunogenic composition
GB201003922D0 (en) 2010-03-09 2010-04-21 Glaxosmithkline Biolog Sa Conjugation process
US9567377B2 (en) 2010-03-10 2017-02-14 Glaxosmithkline Biologicals Sa Immunogenic composition
EA201690310A1 (ru) 2010-04-13 2016-12-30 Селлдекс Терапьютикс Инк. Антитела, связывающие cd27 человека, и их применение
US8501197B2 (en) 2010-04-30 2013-08-06 The Research Foundation for The State of New York Compositions and methods for stimulating immune response against Moraxella catarrhalis
GB201103836D0 (en) 2011-03-07 2011-04-20 Glaxosmithkline Biolog Sa Conjugation process
RU2481401C2 (ru) * 2011-07-15 2013-05-10 Государственное образовательное учреждение высшего профессионального образования "Уральская государственная медицинская академия Министерства здравоохранения и социального развития Российской Федерации" (ГОУ ВПО УГМА Минздравсоцразвития России) СПОСОБ ВЫЯВЛЕНИЯ β-ЛАКТАМАЗОПРОДУЦИРУЮЩИХ ОКСИДАЗОПОЗИТИВНЫХ ГРАМОТРИЦАТЕЛЬНЫХ ДИПЛОКОККОВ, ПОДОЗРИТЕЛЬНЫХ НА ПРИНАДЛЕЖНОСТЬ К MORAХELLA (BRANCHAMELLA) CATARRHALIS
US11210432B2 (en) * 2013-08-20 2021-12-28 Janus Technologies, Inc. Method and apparatus for selectively snooping and capturing data for secure computer interfaces
EP3268037B1 (en) 2015-03-09 2022-08-31 Celldex Therapeutics, Inc. Cd27 agonists
GB201518684D0 (en) 2015-10-21 2015-12-02 Glaxosmithkline Biolog Sa Vaccine
US10228367B2 (en) 2015-12-01 2019-03-12 ProteinSimple Segmented multi-use automated assay cartridge
WO2017184619A2 (en) 2016-04-18 2017-10-26 Celldex Therapeutics, Inc. Agonistic antibodies that bind human cd40 and uses thereof
GB201621686D0 (en) 2016-12-20 2017-02-01 Glaxosmithkline Biologicals Sa Novel methods for inducing an immune response
JP7291633B2 (ja) 2017-05-30 2023-06-15 グラクソスミスクライン バイオロジカルズ ソシエテ アノニム アジュバントを製造する方法
BR112020010790A2 (pt) 2017-12-01 2020-11-10 Glaxosmithkline Biologicals S.A. purificação da saponina
MX2020010913A (es) 2018-04-17 2021-01-08 Celldex Therapeutics Inc Anticuerpos anti-cd27 y anti-pd-l1 y constructos biespecíficos.
JP2021533162A (ja) 2018-08-07 2021-12-02 グラクソスミスクライン バイオロジカルズ ソシエテ アノニム プロセス及びワクチン
CN111157735B (zh) * 2018-11-07 2023-02-07 广州万孚生物技术股份有限公司 凝集性卡他莫拉菌单克隆抗体及其制备方法和应用
EP3886901A1 (en) 2018-11-29 2021-10-06 GlaxoSmithKline Biologicals S.A. Methods for manufacturing an adjuvant
US20220016168A1 (en) 2018-12-11 2022-01-20 Celldex Therapeutics, Inc. Methods of using cd27 antibodies as conditioning treatment for adoptive cell therapy
CA3142300C (en) 2019-06-05 2025-02-04 Glaxosmithkline Biologicals Sa SAPONIN PURIFICATION
CN111778226B (zh) * 2020-07-21 2022-04-05 东北师范大学 一种水稻耐碱胁迫相关的质膜H+-ATPase蛋白及其应用
US20240417459A1 (en) 2021-04-09 2024-12-19 Celldex Therapeutics, Inc. Antibodies against ilt4, bispecific anti-ilt4/pd-l1 antibody and uses thereof
WO2023077521A1 (en) 2021-11-08 2023-05-11 Celldex Therapeutics, Inc Anti-ilt4 and anti-pd-1 bispecific constructs
GB202205833D0 (en) 2022-04-21 2022-06-08 Glaxosmithkline Biologicals Sa Bacteriophage
WO2024017827A1 (en) 2022-07-19 2024-01-25 Glaxosmithkline Biologicals Sa Continuous process for vaccine production

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4675176A (en) * 1983-12-12 1987-06-23 Norden Laboratories Moraxella bovis protease vaccine
US4879213A (en) * 1986-12-05 1989-11-07 Scripps Clinic And Research Foundation Synthetic polypeptides and antibodies related to Epstein-Barr virus early antigen-diffuse
US5552146A (en) * 1991-08-15 1996-09-03 Board Of Regents, The University Of Texas System Methods and compositions relating to useful antigens of Moraxella catarrhalis
US5607846A (en) 1994-05-17 1997-03-04 Research Foundation Of State University Of New York Vaccine for moraxella catarrhalis
US6335018B1 (en) * 1995-05-01 2002-01-01 Aventis Pasteur Limited High molecular weight major outer membrane protein of moraxella
US6440425B1 (en) 1995-05-01 2002-08-27 Aventis Pasteur Limited High molecular weight major outer membrane protein of moraxella
US7341727B1 (en) * 1996-05-03 2008-03-11 Emergent Product Development Gaithersburg Inc. M. catarrhalis outer membrane protein-106 polypeptide, methods of eliciting an immune response comprising same
GB9809683D0 (en) 1998-05-06 1998-07-01 Smithkline Beecham Biolog Novel compounds
GB9812163D0 (en) 1998-06-05 1998-08-05 Smithkline Beecham Biolog Novel compounds

Also Published As

Publication number Publication date
US20020177200A1 (en) 2002-11-28
HK1021299A1 (en) 2000-06-09
GEP20022695B (en) 2002-05-27
CZ352498A3 (cs) 1999-06-16
EA002743B1 (ru) 2002-08-29
DE69723254D1 (de) 2003-08-07
NO985113L (no) 1998-12-28
HUP9902695A2 (hu) 1999-12-28
CN1800359A (zh) 2006-07-12
CN1222618C (zh) 2005-10-12
US6214981B1 (en) 2001-04-10
EP0900025A1 (en) 1999-03-10
UA68332C2 (en) 2004-08-16
PL189995B1 (pl) 2005-10-31
US7576179B2 (en) 2009-08-18
EP0900025B1 (en) 2003-07-02
AU723528B2 (en) 2000-08-31
NZ332896A (en) 2000-05-26
US20070087019A1 (en) 2007-04-19
NO20063711L (no) 1998-12-28
EA199800973A1 (ru) 1999-06-24
BR9711090A (pt) 1999-08-17
WO1997041731A1 (en) 1997-11-13
US20080145916A1 (en) 2008-06-19
ZA973809B (en) 1997-12-01
CA2253636C (en) 2003-04-22
US7914795B2 (en) 2011-03-29
EE04684B1 (et) 2006-08-15
JP4401437B2 (ja) 2010-01-20
ATE244016T1 (de) 2003-07-15
BG64832B1 (bg) 2006-06-30
PL189374B1 (pl) 2005-07-29
PL330935A1 (en) 1999-06-07
CZ298034B6 (cs) 2007-05-30
US7341727B1 (en) 2008-03-11
EE9800373A (et) 1999-04-15
ES2202624T3 (es) 2004-04-01
EP0900025A4 (en) 2000-01-05
AR006999A1 (es) 1999-10-13
HUP9902695A3 (en) 2001-02-28
PL189375B1 (pl) 2005-07-29
US7128910B2 (en) 2006-10-31
CA2253636A1 (en) 1997-11-13
US20100021492A1 (en) 2010-01-28
CN100415871C (zh) 2008-09-03
BG102983A (en) 2000-05-31
SK284812B6 (sk) 2005-12-01
JP2008161194A (ja) 2008-07-17
HK1095358A1 (zh) 2007-05-04
AU3118097A (en) 1997-11-26
NO985113D0 (no) 1998-11-02
NO324816B1 (no) 2007-12-10
JP2000510696A (ja) 2000-08-22
CN1223549A (zh) 1999-07-21
SK150998A3 (en) 1999-05-07
DE69723254T2 (de) 2004-04-22
HU223004B1 (hu) 2004-03-01

Similar Documents

Publication Publication Date Title
TW541314B (en) Moraxella catarrhalis outer membrane protein-106 polypeptide, gene sequence and uses thereof
KR100361562B1 (ko) 프로테이나제k에대해내성을갖는네이쎄리아메닝기티디스의표면단백질
RU2132383C1 (ru) ФРАГМЕНТ ДНК, КОДИРУЮЩИЙ БЕЛОК ВНЕШНЕЙ МЕМБРАНЫ NEISSERIA MENINGITIDIS ШТАММА В:4:Р1:15, БЕЛОК ВНЕШНЕЙ МЕМБРАНЫ NEISSERIA MENINGITIDIS, РЕКОМБИНАНТНАЯ ПЛАЗМИДНАЯ ДНК pМ-6, ШТАММ БАКТЕРИЙ ESCHERICHIA COLI НВМ 64, СПОСОБ ПОЛУЧЕНИЯ БЕЛКА ВНЕШНЕЙ МЕМБРАНЫ NEISSERIA MENINGITIDIS, ВАКЦИННАЯ КОМПОЗИЦИЯ
JPH06504446A (ja) 肺炎球菌タンパクの構造遺伝子
US20090053292A1 (en) Moraxella catarrhalis protein, nucleic acid sequence and uses thereof
CA2550455C (en) Haemophilus influenzae type iv pili
JPH11504206A (ja) 防御用ヘリコバクター抗原
JP2006502696A (ja) 病原菌株に特異的な新規生成物およびそのワクチンとしての使用および免疫療法における使用
CN100484956C (zh) 源自粘膜炎莫拉氏菌的化合物
CA2328130A1 (en) Moraxella catarrhalis proteins
IL111102A (en) Proteins, peptides and oligopeptides of BRANHAMELLA CATARRHALIS extra-membrane protein, nucleic acids encoding them, method of preparation and use as vaccine formulations
KR100500000B1 (ko) 모락셀라카타르할리스외측막단백질-16폴리펩티드,이의유전자서열및이의용도
CN100387718C (zh) 抗蛋白酶k降解的脑膜炎奈瑟氏球菌表面蛋白
HK1095358B (en) Moraxella catarrhalis outer membrane protein-106 polypeptide, gene sequence and use thereof
JP2008525008A (ja) 髄膜炎菌に対するワクチン
JP2009520491A (ja) 髄膜炎菌に対するワクチン

Legal Events

Date Code Title Description
GD4A Issue of patent certificate for granted invention patent
MM4A Annulment or lapse of patent due to non-payment of fees