UA101407C2 - Стабильная комбинированная фармацевтическая композиция амлодипина и бисопролола фумарат - Google Patents

Стабильная комбинированная фармацевтическая композиция амлодипина и бисопролола фумарат

Info

Publication number
UA101407C2
UA101407C2 UAA201105446A UAA201105446A UA101407C2 UA 101407 C2 UA101407 C2 UA 101407C2 UA A201105446 A UAA201105446 A UA A201105446A UA A201105446 A UAA201105446 A UA A201105446A UA 101407 C2 UA101407 C2 UA 101407C2
Authority
UA
Ukraine
Prior art keywords
amlodipine
pharmaceutical composition
bisoprolol fumarate
combined pharmaceutical
stable combined
Prior art date
Application number
UAA201105446A
Other languages
English (en)
Russian (ru)
Ukrainian (uk)
Inventor
Лазло Вагнер
Золт Жигмонд
Дьордь Уйфалушши
Хузар Магдолна Левентизне
Петер Тонка-Надь
Эржбет Барця
Ласлон Гора
Эдит Селецки
Агнеш Фюльоп
Original Assignee
Эгиш Дьйодьсердьяр Нильваношан Мюкьодо Ресвеньтаршашаг
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Эгиш Дьйодьсердьяр Нильваношан Мюкьодо Ресвеньтаршашаг filed Critical Эгиш Дьйодьсердьяр Нильваношан Мюкьодо Ресвеньтаршашаг
Publication of UA101407C2 publication Critical patent/UA101407C2/ru

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138—Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42—Oxazoles
    • A61K31/422—Oxazoles not condensed and containing further heterocyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4422—1,4-Dihydropyridines, e.g. nifedipine, nicardipine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2013—Organic compounds, e.g. phospholipids, fats
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/2027—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2059—Starch, including chemically or physically modified derivatives; Amylose; Amylopectin; Dextrin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4866—Organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Hydrogenated Pyridines (AREA)
  • Peptides Or Proteins (AREA)
  • Packages (AREA)
UAA201105446A 2008-09-30 2009-09-30 Стабильная комбинированная фармацевтическая композиция амлодипина и бисопролола фумарат UA101407C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HUP0800591A HU230877B1 (hu) 2008-09-30 2008-09-30 Stabil kombinációs gyógyszerkészítmény
PCT/HU2009/000085 WO2010038091A2 (en) 2008-09-30 2009-09-30 Stable combination pharmaceutical composition

Publications (1)

Publication Number Publication Date
UA101407C2 true UA101407C2 (ru) 2013-03-25

Family

ID=89988527

Family Applications (1)

Application Number Title Priority Date Filing Date
UAA201105446A UA101407C2 (ru) 2008-09-30 2009-09-30 Стабильная комбинированная фармацевтическая композиция амлодипина и бисопролола фумарат

Country Status (31)

Country Link
EP (2) EP2344141B1 (cs)
KR (1) KR101772619B1 (cs)
CN (1) CN102164585B (cs)
AT (2) AT510866A3 (cs)
BG (1) BG66274B1 (cs)
CH (1) CH702345B1 (cs)
CY (1) CY1122084T1 (cs)
CZ (2) CZ308237B6 (cs)
DE (1) DE202009019152U1 (cs)
DK (1) DK2344141T3 (cs)
EA (2) EA026238B9 (cs)
EE (1) EE05723B1 (cs)
ES (2) ES2739900T3 (cs)
GE (1) GEP20135859B (cs)
HR (3) HRP20191373T1 (cs)
HU (3) HU230877B1 (cs)
LT (3) LT2359815T (cs)
ME (1) ME03774B (cs)
MX (2) MX2011003407A (cs)
MY (1) MY175270A (cs)
PL (3) PL394605A1 (cs)
PT (3) PT2344141T (cs)
RO (1) RO127490B1 (cs)
RS (3) RS60784B1 (cs)
RU (2) RU2687282C2 (cs)
SG (1) SG194392A1 (cs)
SI (2) SI2344141T1 (cs)
SK (2) SK288593B6 (cs)
SM (1) SMT201900434T1 (cs)
UA (1) UA101407C2 (cs)
WO (1) WO2010038091A2 (cs)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU230877B1 (hu) 2008-09-30 2018-11-29 EGIS Gyógyszergyár NyR Stabil kombinációs gyógyszerkészítmény
CN101766611B (zh) * 2010-02-09 2011-10-12 施慧达药业集团(吉林)有限公司 一种左旋氨氯地平或其可药用盐和β受体阻滞剂的药物组合物及其应用
HK1205683A1 (en) 2012-02-17 2015-12-24 埃吉斯药物私人有限公司 Pharmaceutical formulation having improved stability
SG11201509998WA (en) * 2013-06-13 2016-01-28 Akebia Therapeutics Inc Compositions and methods for treating anemia
HUP1300496A2 (hu) 2013-08-16 2015-03-02 Egis Gyogyszergyar Nyilvanosan Muekoedoe Reszvenytarsasag Stabil kombinációs gyógyszerkészítmény
FR3027803B1 (fr) * 2014-11-05 2018-02-09 Les Laboratoires Servier Composition pharmaceutique comprenant un betabloquant et un inhibiteur de l'enzyme de conversion
PH12018502155B1 (en) 2016-04-20 2024-03-27 Servier Lab Pharmaceutical composition comprising a beta blocker, a converting enzyme inhibitor and an antihypertensive or an nsaid
JP2025528476A (ja) 2022-09-07 2025-08-28 キナスト ラッセ Ａｐｉ含量が増加したアムロジピンの即時放出経口医薬形態
CN116687926B (zh) * 2023-07-27 2023-12-12 石家庄四药有限公司 一种比索洛尔氨氯地平复方片剂及其制备方法

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU221810B1 (hu) * 1997-08-12 2003-01-28 EGIS Gyógyszergyár Rt. Eljárás amlodipin-bezilát előállítására és az eljárás intermedierjei
GB0001621D0 (en) * 2000-01-26 2000-03-15 Astrazeneca Ab Pharmaceutical compositions
AT5874U1 (de) * 2000-12-29 2003-01-27 Bioorg Bv Pharmazeutische zubereitungen enthaltend amlodipinmaleat
CA2433181C (en) 2000-12-29 2005-11-22 Pfizer Limited Amlodipine hemifumarate
AU2001100431A4 (en) * 2001-10-03 2001-11-01 Pfizer Limited Pharmaceutical compositions comprising amlodipine maleate
WO2003032954A1 (en) 2001-10-17 2003-04-24 Dr. Reddy's Laboratories Ltd. Stabilized pharmaceutical formulations containing amlodipine maleate
US20060270715A1 (en) * 2003-02-28 2006-11-30 Singh Romi B Dosage forms of amlodipine and processes for their preparation
WO2005051350A2 (en) * 2003-10-28 2005-06-09 Torrent Pharmaceuticals Limited Water dispersible tablet
WO2005099699A1 (en) * 2004-04-07 2005-10-27 Sepracor Inc. Combination of (s)-amlodipine and a beta-blocker, and methods for reducing hypertension
IN224215B (cs) * 2004-08-05 2009-02-06
WO2006059217A1 (en) * 2004-12-01 2006-06-08 Ranbaxy Laboratories Limited Stable solid dosage forms of amlodipine besylate and processes for their preparation
CZ2005141A3 (cs) * 2005-03-07 2006-04-12 Lunaria, Spol. S. R. O. Lécivý prípravek na bázi amlodipin-besilátu se zvýsenou stabilitou
GB2444904B (en) * 2006-12-05 2008-11-05 Michael Hilary Burke A Process For The Preparation of an Orally Administrable Unit Dose Tablet
HU230877B1 (hu) 2008-09-30 2018-11-29 EGIS Gyógyszergyár NyR Stabil kombinációs gyógyszerkészítmény

Also Published As

Publication number Publication date
AT510866A2 (de) 2012-07-15
EP2359815A1 (en) 2011-08-24
EA201691869A1 (ru) 2017-04-28
EA026238B9 (ru) 2017-05-31
BG66274B1 (bg) 2012-12-28
EP2359815B1 (en) 2020-01-08
CZ30825U1 (cs) 2017-07-11
PL2344141T3 (pl) 2019-10-31
RU2011112047A (ru) 2012-11-10
BG110927A (bg) 2011-09-30
AT14769U1 (de) 2016-05-15
RO127490A2 (ro) 2012-06-29
PT2010038091Y (pt) 2020-02-10
SK50232011A3 (sk) 2011-08-04
SK72017U1 (sk) 2017-08-02
WO2010038091A3 (en) 2010-09-23
MX2011003407A (es) 2011-06-20
HUE049948T2 (hu) 2020-11-30
EP2344141A2 (en) 2011-07-20
CY1122084T1 (el) 2020-11-25
WO2010038091A2 (en) 2010-04-08
CZ2011252A3 (cs) 2011-07-07
PT2359815T (pt) 2020-04-16
HRP20200614T1 (hr) 2020-10-02
RU2549437C2 (ru) 2015-04-27
HK1155976A1 (zh) 2012-06-01
SG194392A1 (en) 2013-11-29
PL2359815T3 (pl) 2020-11-30
EA026238B1 (ru) 2017-03-31
DE202009019152U1 (de) 2017-03-06
ES2385988A1 (es) 2012-08-06
EE201100029A (et) 2011-06-15
RO127490B1 (ro) 2022-01-28
RU2014139476A (ru) 2015-06-20
GEP20135859B (en) 2013-06-25
HU230877B1 (hu) 2018-11-29
HRP20110162A8 (hr) 2019-03-22
SI2344141T1 (sl) 2019-09-30
ME03774B (me) 2021-04-20
LT2359815T (lt) 2020-04-27
HRP20191373T1 (hr) 2019-11-01
HUE045326T2 (hu) 2019-12-30
EA038392B1 (ru) 2021-08-20
AT510866A3 (de) 2014-06-15
LT2011012A (lt) 2011-10-25
MX382264B (es) 2025-03-11
HU0800591D0 (en) 2008-11-28
HRP20110162B1 (hr) 2019-09-20
ES2385988B2 (es) 2013-12-11
HUP0800591A2 (en) 2010-10-28
KR101772619B1 (ko) 2017-08-29
CH702345B1 (de) 2014-05-15
RS60686B1 (sr) 2020-09-30
RU2687282C2 (ru) 2019-05-13
CN102164585A (zh) 2011-08-24
SK7997Y1 (sk) 2018-02-05
HRP20110162A2 (hr) 2011-06-30
PT2344141T (pt) 2019-08-06
SI2359815T1 (sl) 2020-10-30
EA201100430A1 (ru) 2011-10-31
EE05723B1 (et) 2014-10-15
SMT201900434T1 (it) 2019-09-09
EP2344141B1 (en) 2019-05-01
RS60784B1 (sr) 2020-10-30
RS59201B1 (sr) 2019-10-31
MY175270A (en) 2020-06-17
LT2344141T (lt) 2019-08-26
ES2739900T3 (es) 2020-02-04
WO2010038091A9 (en) 2011-04-07
LT5815B (lt) 2012-02-27
PL394605A1 (pl) 2011-09-26
DK2344141T3 (da) 2019-08-05
RS20110136A1 (sr) 2012-08-31
CZ308237B6 (cs) 2020-03-18
SK288593B6 (sk) 2018-09-03
CN102164585B (zh) 2016-04-27
KR20110063563A (ko) 2011-06-10

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