TNSN99017A1 - Gene de streptomyces avermitilis commandant le rapport des avermectines b2 : b1 et procede nouveau pour la production d'avermectines. - Google Patents
Gene de streptomyces avermitilis commandant le rapport des avermectines b2 : b1 et procede nouveau pour la production d'avermectines.Info
- Publication number
- TNSN99017A1 TNSN99017A1 TNTNSN99017A TNSN99017A TNSN99017A1 TN SN99017 A1 TNSN99017 A1 TN SN99017A1 TN TNSN99017 A TNTNSN99017 A TN TNSN99017A TN SN99017 A TNSN99017 A TN SN99017A TN SN99017 A1 TNSN99017 A1 TN SN99017A1
- Authority
- TN
- Tunisia
- Prior art keywords
- avermectins
- gene
- avermitilized
- streptomyces
- report
- Prior art date
Links
- 239000005660 Abamectin Substances 0.000 title abstract 4
- 108090000623 proteins and genes Proteins 0.000 title abstract 3
- 241000187747 Streptomyces Species 0.000 title 1
- RRZXIRBKKLTSOM-XPNPUAGNSA-N avermectin B1a Chemical compound C1=C[C@H](C)[C@@H]([C@@H](C)CC)O[C@]11O[C@H](C\C=C(C)\[C@@H](O[C@@H]2O[C@@H](C)[C@H](O[C@@H]3O[C@@H](C)[C@H](O)[C@@H](OC)C3)[C@@H](OC)C2)[C@@H](C)\C=C\C=C/2[C@]3([C@H](C(=O)O4)C=C(C)[C@@H](O)[C@H]3OC\2)O)C[C@H]4C1 RRZXIRBKKLTSOM-XPNPUAGNSA-N 0.000 abstract 1
- 229940058299 avermectines Drugs 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 230000000590 parasiticidal effect Effects 0.000 abstract 1
- 239000002297 parasiticide Substances 0.000 abstract 1
- 102000040430 polynucleotide Human genes 0.000 abstract 1
- 108091033319 polynucleotide Proteins 0.000 abstract 1
- 239000002157 polynucleotide Substances 0.000 abstract 1
- 239000013598 vector Substances 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/44—Preparation of O-glycosides, e.g. glucosides
- C12P19/60—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin
- C12P19/62—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin the hetero ring having eight or more ring members and only oxygen as ring hetero atoms, e.g. erythromycin, spiramycin, nystatin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
- C12N15/76—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora for Actinomyces; for Streptomyces
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/88—Lyases (4.)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
- C12P17/181—Heterocyclic compounds containing oxygen atoms as the only ring heteroatoms in the condensed system, e.g. Salinomycin, Septamycin
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Plant Pathology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Enzymes And Modification Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US7463698P | 1998-02-13 | 1998-02-13 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| TNSN99017A1 true TNSN99017A1 (fr) | 2005-11-10 |
Family
ID=22120706
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| TNTNSN99017A TNSN99017A1 (fr) | 1998-02-13 | 1999-02-10 | Gene de streptomyces avermitilis commandant le rapport des avermectines b2 : b1 et procede nouveau pour la production d'avermectines. |
Country Status (32)
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20040053390A (ko) * | 1998-02-13 | 2004-06-23 | 화이자 프로덕츠 인코포레이티드 | 아베르멕틴의 비2:비1의 비를 제어할 수 있는 스트렙토마이세스 아베르미틸리스 유전자 |
| US6248579B1 (en) * | 1998-02-13 | 2001-06-19 | Pfizer Inc | Streptomyces avermitilis gene directing the ratio of B2:B1 avermectins |
| JP3884651B2 (ja) | 1999-08-12 | 2007-02-21 | ファイザー・プロダクツ・インク | Ｂ２アベルメクチン：ｂ１アベルメクチンの比を指示するストレプトミセス・アベルミティリス遺伝子 |
| US7630836B2 (en) | 2001-05-30 | 2009-12-08 | The Kitasato Institute | Polynucleotides |
| ES2321827T3 (es) * | 2002-02-12 | 2009-06-12 | Pfizer Products Inc. | Gen de streptomyces avermitilis que rige la relacion de avermectinas b2-b1. |
| CN107338210B (zh) * | 2017-09-05 | 2021-08-17 | 天津科技大学 | 一种阿维链霉菌合成培养基及其发酵液的制备方法 |
| CN111269296B (zh) * | 2020-03-06 | 2021-11-05 | 山东大学 | 一种nLsA蛋白及其结构基因和应用 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE434277B (sv) * | 1976-04-19 | 1984-07-16 | Merck & Co Inc | Sett att framstella nya antihelmintiskt verkande foreningar genom odling av streptomyces avermitilis |
| US4429042A (en) * | 1978-09-08 | 1984-01-31 | Merck & Co., Inc. | Strain of Streptomyces for producing antiparasitic compounds |
| IN167980B (enrdf_load_stackoverflow) * | 1987-01-23 | 1991-01-19 | Pfizer | |
| DE3881147T2 (de) * | 1987-10-23 | 1993-09-02 | Pfizer | Verfahren zur herstellung von aglykonen von avermectin und sie enthaltende kulturen. |
| JPH0747171B2 (ja) * | 1988-09-20 | 1995-05-24 | 株式会社東芝 | 圧延機の設定方法および装置 |
| ES2079436T3 (es) * | 1989-03-31 | 1996-01-16 | Merck & Co Inc | Clonacion de genes de streptomyces avermitilis para biosintesis de avermectinas y procedimientos para su uso. |
| US5252474A (en) * | 1989-03-31 | 1993-10-12 | Merck & Co., Inc. | Cloning genes from Streptomyces avermitilis for avermectin biosynthesis and the methods for their use |
| JP2888586B2 (ja) * | 1990-03-05 | 1999-05-10 | 社団法人北里研究所 | エバーメクチンの特定成分を選択生産するための微生物およびその選択的製造法 |
| FI942725L (fi) * | 1993-12-16 | 1995-06-17 | Pfizer | Haaraketjuista alfaketohappodenydrogenaasikompleksia koodaavia geenejä Streptomyces avermitiliksesta |
| KR20040053390A (ko) * | 1998-02-13 | 2004-06-23 | 화이자 프로덕츠 인코포레이티드 | 아베르멕틴의 비2:비1의 비를 제어할 수 있는 스트렙토마이세스 아베르미틸리스 유전자 |
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1999
- 1999-01-25 KR KR10-2004-7008310A patent/KR20040053390A/ko not_active Ceased
- 1999-01-25 HR HR20000539A patent/HRP20000539A2/hr not_active Application Discontinuation
- 1999-01-25 EA EA200000758A patent/EA003905B1/ru not_active IP Right Cessation
- 1999-01-25 JP JP2000531570A patent/JP2002503473A/ja active Pending
- 1999-01-25 AU AU18878/99A patent/AU752343C/en not_active Ceased
- 1999-01-25 KR KR10-2000-7008870A patent/KR100499214B1/ko not_active Expired - Fee Related
- 1999-01-25 KR KR10-2004-7015691A patent/KR20040099389A/ko not_active Ceased
- 1999-01-25 PL PL99342468A patent/PL194270B1/pl not_active IP Right Cessation
- 1999-01-25 NZ NZ518657A patent/NZ518657A/en unknown
- 1999-01-25 IL IL13761099A patent/IL137610A0/xx unknown
- 1999-01-25 WO PCT/IB1999/000130 patent/WO1999041389A1/en not_active Application Discontinuation
- 1999-01-25 EP EP99900270A patent/EP1053335A1/en not_active Withdrawn
- 1999-01-25 CN CNA2004100054154A patent/CN1521180A/zh active Pending
- 1999-01-25 CN CN99805027A patent/CN1297485A/zh active Pending
- 1999-01-25 HU HU0100784A patent/HUP0100784A3/hu not_active Application Discontinuation
- 1999-01-25 SK SK1172-2000A patent/SK11722000A3/sk unknown
- 1999-01-25 NZ NZ505676A patent/NZ505676A/xx unknown
- 1999-01-25 CA CA002521289A patent/CA2521289A1/en not_active Abandoned
- 1999-01-25 BR BR9907893-7A patent/BR9907893A/pt not_active Application Discontinuation
- 1999-01-25 CA CA002320031A patent/CA2320031A1/en not_active Abandoned
- 1999-01-25 YU YU50900A patent/YU50900A/sh unknown
- 1999-01-26 PA PA19998467601A patent/PA8467601A1/es unknown
- 1999-02-01 GT GT199900014A patent/GT199900014A/es unknown
- 1999-02-05 HN HN1991000008A patent/HN1999000008A/es unknown
- 1999-02-08 PE PE1999000099A patent/PE20000352A1/es not_active Application Discontinuation
- 1999-02-09 TW TW088102005A patent/TW585910B/zh active
- 1999-02-10 DZ DZ990021A patent/DZ2720A1/xx active
- 1999-02-10 MA MA25460A patent/MA24760A1/fr unknown
- 1999-02-10 TN TNTNSN99017A patent/TNSN99017A1/fr unknown
- 1999-02-11 AP APAP/P/1999/001463A patent/AP9901463A0/en unknown
- 1999-02-11 AR ARP990100571A patent/AR018085A1/es unknown
- 1999-02-12 CO CO99008652A patent/CO5070698A1/es unknown
- 1999-02-12 ZA ZA9901138A patent/ZA991138B/xx unknown
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2000
- 2000-07-20 IS IS5567A patent/IS5567A/is unknown
- 2000-08-04 OA OA1200000217A patent/OA11449A/en unknown
- 2000-08-11 NO NO20004044A patent/NO20004044L/no not_active Application Discontinuation
- 2000-09-12 BG BG104759A patent/BG64911B1/bg unknown
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2004
- 2004-04-27 JP JP2004130624A patent/JP4011036B2/ja not_active Expired - Fee Related
-
2007
- 2007-05-31 IL IL183596A patent/IL183596A0/en unknown
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