SK404191A3 - Indole derivatives, method of their production and pharmaceutical preparation with their contents - Google Patents
Indole derivatives, method of their production and pharmaceutical preparation with their contents Download PDFInfo
- Publication number
- SK404191A3 SK404191A3 SK4041-91A SK404191A SK404191A3 SK 404191 A3 SK404191 A3 SK 404191A3 SK 404191 A SK404191 A SK 404191A SK 404191 A3 SK404191 A3 SK 404191A3
- Authority
- SK
- Slovakia
- Prior art keywords
- compound
- formula
- group
- active ingredient
- formulated
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D203/00—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom
- C07D203/04—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D203/06—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D203/08—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring nitrogen atom
- C07D203/14—Heterocyclic compounds containing three-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring nitrogen atom with carbocyclic rings directly attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/12—Radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
- C07D209/16—Tryptamines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D209/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an alkyl or cycloalkyl radical attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB848419575A GB8419575D0 (en) | 1984-08-01 | 1984-08-01 | Chemical compounds |
Publications (2)
Publication Number | Publication Date |
---|---|
SK404191A3 true SK404191A3 (en) | 1995-09-13 |
SK277952B6 SK277952B6 (en) | 1995-09-13 |
Family
ID=10564759
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SK4041-91A SK277952B6 (en) | 1984-08-01 | 1991-12-23 | Indole derivatives, method of their production and pharmaceutical preparation with their contents |
Country Status (42)
Country | Link |
---|---|
US (1) | US5037845A (fr) |
JP (1) | JPH0623197B2 (fr) |
KR (1) | KR930003759B1 (fr) |
AT (1) | AT386196B (fr) |
AU (1) | AU573878B2 (fr) |
BE (1) | BE903006A (fr) |
CA (1) | CA1241004A (fr) |
CH (1) | CH666026A5 (fr) |
CZ (1) | CZ280530B6 (fr) |
DE (1) | DE3527648A1 (fr) |
DK (1) | DK158942C (fr) |
DO (1) | DOP1989004759A (fr) |
EC (1) | ECSP941096A (fr) |
EG (1) | EG17283A (fr) |
ES (6) | ES8700234A1 (fr) |
FI (1) | FI78466C (fr) |
FR (1) | FR2568571B1 (fr) |
GB (1) | GB8419575D0 (fr) |
GR (1) | GR851850B (fr) |
HK (1) | HK33289A (fr) |
HU (1) | HU201738B (fr) |
IE (1) | IE58122B1 (fr) |
IL (1) | IL75986A (fr) |
IS (1) | IS1430B6 (fr) |
IT (1) | IT1207325B (fr) |
JO (1) | JO1379B1 (fr) |
KE (1) | KE3858A (fr) |
LU (2) | LU86032A1 (fr) |
MA (1) | MA20499A1 (fr) |
MX (2) | MX159672A (fr) |
NL (2) | NL188642C (fr) |
NO (2) | NO164653C (fr) |
NZ (1) | NZ212948A (fr) |
PH (2) | PH22850A (fr) |
PL (1) | PL146005B1 (fr) |
PT (1) | PT80900B (fr) |
SE (1) | SE452460B (fr) |
SK (1) | SK277952B6 (fr) |
SU (1) | SU1498386A3 (fr) |
UA (1) | UA6329A1 (fr) |
ZA (1) | ZA855818B (fr) |
ZW (1) | ZW12485A1 (fr) |
Families Citing this family (65)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5270333A (en) * | 1986-01-28 | 1993-12-14 | Glaxo Group Limited | Indole derivatives |
US5935925A (en) * | 1990-05-08 | 1999-08-10 | Synaptic Pharmaceutical Corporation | Methods of treating migraine and compounds useful for such methods |
US5155218A (en) | 1990-05-08 | 1992-10-13 | Neurogenetic Corporation | Dna encoding human 5-ht1d receptors |
GB9013845D0 (en) * | 1990-06-21 | 1990-08-15 | Glaxo Group Ltd | Process |
GB9022250D0 (en) * | 1990-10-12 | 1990-11-28 | Glaxo Group Ltd | Medicaments |
GB9102579D0 (en) * | 1991-01-24 | 1991-03-27 | Glaxo Group Ltd | Compositions |
GB9101592D0 (en) * | 1991-01-24 | 1991-03-06 | Glaxo Group Ltd | Compositions |
CZ283018B6 (cs) * | 1991-02-01 | 1997-12-17 | Merck Sharp And Dohme Limited | Deriváty imidazolu, triazolu a tetrazolu a farmaceutické přípravky na jejich bázi |
GB9104890D0 (en) * | 1991-03-08 | 1991-04-24 | Glaxo Group Ltd | Compositions |
AT399870B (de) * | 1991-06-06 | 1995-08-25 | Vita Invest Sa | Verfahren zur herstellung von 3-(2-(dimethylamino)ethyl)-n-methyl-1h-indol-5- ethansulfonamid |
GB9209882D0 (en) * | 1992-05-07 | 1992-06-24 | Glaxo Lab Sa | Compositions |
ES2059236B1 (es) * | 1992-06-18 | 1995-06-16 | Imidex S A | Procedimiento para la sintesis de la 3-(2-dimetilamino) etil)-n-metil-1h-indol-5-metanosulfonamida. |
ES2055651B1 (es) * | 1992-07-20 | 1995-03-01 | Vita Invest Sa | Procedimiento para la obtencion de nuevas amidinas derivadas de 3-aminoetilindoles. |
IL106445A (en) * | 1992-07-30 | 1998-01-04 | Merck Sharp & Dohme | History of 1,2,4-Trans-Triazole 4-Transform, Preparation and Pharmaceutical Preparations Containing Them |
AT399871B (de) * | 1993-02-15 | 1995-08-25 | Vita Invest Sa | Verfahren zur herstellung von 2-carboxy-3-(2- (dimethylamino)ethyl)-n-methyl-1h-indol-5- methansulfonamid und dessen niederalkylestern |
US5807571A (en) * | 1993-05-06 | 1998-09-15 | Lts Lohmann Therapie-Systeme Gmbh | Transdermal therapeutic systems for administering indole serotonin agonists |
GB9401436D0 (en) * | 1994-01-26 | 1994-03-23 | Wellcome Found | Therapeutic heterocyclic compounds |
ES2084560B1 (es) * | 1994-03-09 | 1997-01-16 | Almirall Lab | Procedimiento de preparacion de derivados el indol. |
ES2079323B1 (es) * | 1994-06-21 | 1996-10-16 | Vita Invest Sa | Derivados de indol utiles para el tratamiento de la migraña, composicion y uso correspondientes. |
CA2195107A1 (fr) * | 1994-08-02 | 1996-02-15 | Richard Alexander Jelley | Derives de l'azetidine, de la pyrrolidine et de la piperidine |
US5521197A (en) | 1994-12-01 | 1996-05-28 | Eli Lilly And Company | 3-<1-alkylenearyl>-4-<1,2,3,6-tetrahydropyridinyl>-and 3-<1-alkylenearyl>-4-piperidinyl-1h-indoles: new 5-HT1F agonists |
US8022095B2 (en) | 1996-08-16 | 2011-09-20 | Pozen, Inc. | Methods of treating headaches using 5-HT agonists in combination with long-acting NSAIDs |
WO1998011895A1 (fr) * | 1996-09-18 | 1998-03-26 | Eli Lilly And Company | Methode de prevention de migraine |
CA2268164A1 (fr) * | 1996-10-08 | 1998-04-16 | Yao-Chang Xu | Nouveaux agonistes de la serotonine 5-ht1f |
GB9714383D0 (en) * | 1997-07-08 | 1997-09-10 | Pfizer Ltd | Improved process |
US6416472B1 (en) | 1997-11-06 | 2002-07-09 | Edus Inc. | Method and device for measuring cognitive efficiency |
US6066092A (en) * | 1997-11-06 | 2000-05-23 | Cady; Roger K. | Preemptive prophylaxis of migraine device and method |
US7189753B1 (en) | 1997-11-06 | 2007-03-13 | Cady Roger K | Preemptive prophylaxis of migraine |
AT500063A1 (de) * | 1999-11-23 | 2005-10-15 | Sandoz Ag | Beschichtete tablettenkerne |
US6951654B2 (en) * | 2001-03-27 | 2005-10-04 | Galen (Chemicals) Limited | Intravaginal drug delivery devices for the administration of an antimicrobial agent |
US8329734B2 (en) * | 2009-07-27 | 2012-12-11 | Afgin Pharma Llc | Topical therapy for migraine |
US20030013753A1 (en) * | 2001-06-05 | 2003-01-16 | Ronald Aung-Din | Transdermal migraine therapy |
FR2827287B1 (fr) * | 2001-07-13 | 2003-10-31 | Servier Lab | Nouveaux derives de benzene sulfonamide, leur procede de preparation et les compositions pharmaceutiques qui les contiennent |
EP2316468A1 (fr) | 2002-02-22 | 2011-05-04 | Shire LLC | Système de distribution et méthodes de protection et d'administration de dextroamphetamine |
US20060106227A1 (en) * | 2002-06-13 | 2006-05-18 | Dr Reddy's Laboratories Limited | 3-'2-(Dimethylamino) ethyl!-n-methyl-1h-indole-5-methanesulfonamide and the succinate thereof |
US20040068000A1 (en) * | 2002-10-02 | 2004-04-08 | Mintong Guo | Compression coated tablets |
CN1176649C (zh) * | 2002-10-16 | 2004-11-24 | 上海医药工业研究院 | 舒马普坦干粉吸入剂及其制备方法 |
CA2508290C (fr) | 2002-12-20 | 2017-02-28 | Ciba Specialty Chemicals Holding Inc. | Synthese d'amines et intermediaires pour cette synthese |
US20080213363A1 (en) * | 2003-01-23 | 2008-09-04 | Singh Nikhilesh N | Methods and compositions for delivering 5-HT3 antagonists across the oral mucosa |
WO2004076403A1 (fr) * | 2003-02-24 | 2004-09-10 | Transform Pharmaceuticals, Inc. | Formes cristallines du sumatriptan, compositions pharmaceutiques et procedes |
WO2004099141A1 (fr) * | 2003-05-12 | 2004-11-18 | Ramesh Babu Potluri | Nouveau procede pour la preparation de derives d'indole |
KR20060015641A (ko) * | 2003-06-06 | 2006-02-17 | 글락소 그룹 리미티드 | 트립탄 및 nsaid를 포함하는 조성물 |
CA2529528A1 (fr) * | 2003-06-20 | 2004-12-29 | Ronald Aung-Din | Therapie locale pour le traitement des migraines, des claquages musculaires, des spasmes musculaires, de la spasticite et d'etats apparentes |
GB2407498B (en) * | 2003-10-30 | 2008-06-11 | Cipla Ltd | Oral formulations for 5-HT receptor agonists with reduced degradation of active ingredient |
CA2569964A1 (fr) * | 2004-06-10 | 2005-12-29 | Duramed Pharmaceuticals, Inc. | Formulations de sumatriptan absorbables au travers des membranes biologiques, et methodes de production et d'utilisation desdites formulations |
JP5833804B2 (ja) * | 2005-04-13 | 2015-12-16 | ニューラクソン,インコーポレーテッド | Nos阻害活性を有する置換インドール化合物 |
WO2007070504A2 (fr) * | 2005-12-13 | 2007-06-21 | Morton Grove Pharmaceuticals, Inc. | Compositions orales liquides de sumatriptan stables et de gout agreable |
CN101466709B (zh) * | 2006-04-13 | 2013-03-20 | 轴突公司 | 具有nos抑制活性的1,5和3,6-取代的吲哚化合物 |
AU2007310949A1 (en) | 2006-10-19 | 2008-04-24 | Auspex Pharmaceuticals, Inc. | Substituted indoles |
US20090076121A1 (en) * | 2007-09-14 | 2009-03-19 | Protia, Llc | Deuterium-enriched sumatriptan |
WO2009064505A1 (fr) * | 2007-11-16 | 2009-05-22 | The Arizona Board Of Regents On Behalf Of The University Of Arizona | Procédés de traitement de la douleur viscérale |
EP2220074A4 (fr) * | 2007-11-16 | 2012-01-04 | Neuraxon Inc | Composés d'indole 3,5-substitués ayant une activité d'inhibition de la réabsorption de la nos et de la noradrénaline |
BRPI0820632A2 (pt) * | 2007-11-16 | 2015-06-16 | Neuraxon Inc | Compostos de indol e métodos para tratamento de dor visceral |
WO2009128089A2 (fr) * | 2008-02-11 | 2009-10-22 | Matrix Laboratories Limited | Nouvelle forme de solvate de succinate de sumatriptan et procédé de préparation d'un sel de sumatriptan l'utilisant |
US20090252791A1 (en) * | 2008-04-02 | 2009-10-08 | Venkata Nookaraju Sreedharala | Pharmaceutical compositions comprising a triptan and a nonsteroidal anti-inflammatory drug |
KR101517415B1 (ko) * | 2008-05-14 | 2015-05-07 | 에스케이바이오팜 주식회사 | 난용성 항경련제를 함유하는 경비 항경련성 약학 조성물 |
CA2729346A1 (fr) * | 2008-06-30 | 2010-01-14 | Afgin Pharma, Llc | Traitement neuro-affectif regional topique |
JP2012506404A (ja) * | 2008-10-22 | 2012-03-15 | ノバルティス アーゲー | 片頭痛処置用組み合わせ剤 |
NZ599344A (en) | 2009-09-25 | 2015-02-27 | Reddy’S Lab Ltd Dr | Formulations comprising triptan compounds |
US11337962B2 (en) | 2009-09-25 | 2022-05-24 | Upsher-Smith Laboratories, Llc | Formulations comprising triptan compounds |
JP5660817B2 (ja) * | 2010-07-21 | 2015-01-28 | 高田製薬株式会社 | スマトリプタンコハク酸塩を含有する内用液剤 |
CN102432520B (zh) * | 2011-11-21 | 2013-10-09 | 山东新华制药股份有限公司 | 3-[2-(二甲氨基)乙基]-n-甲基吲哚-5-甲烷磺酰胺琥珀酸盐的制备方法 |
US10383816B2 (en) | 2015-03-02 | 2019-08-20 | Afgin Pharma, Llc | Topical regional neuro-affective therapy with cannabinoid combination products |
AU2016226267A1 (en) | 2015-03-02 | 2017-09-28 | Afgin Pharma, Llc | Topical regional neuro-affective therapy with cannabinoids |
US20180049994A1 (en) | 2016-08-16 | 2018-02-22 | Afgin Pharma, Llc | Topical regional neuro-affective therapy with caryophyllene |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE311728C (fr) * | ||||
US3322787A (en) * | 1964-09-25 | 1967-05-30 | Merck & Co Inc | Alpha-hydrazino-beta-(3-indolyl) alkanoic acid derivatives |
IT1036004B (it) * | 1968-05-21 | 1979-10-30 | Abc Ist Biolog Chem Spa | Acidt 3 indolil adetoidrossamici |
US4283410A (en) * | 1978-06-15 | 1981-08-11 | Miles Laboratories, Inc. | 3-Amino or amido-2-(1H-indol-3-yl) propanoic acid derivatives |
ZA795239B (en) * | 1978-10-12 | 1980-11-26 | Glaxo Group Ltd | Heterocyclic compounds |
DE3131728A1 (de) * | 1980-08-12 | 1982-03-11 | Glaxo Group Ltd., London | Indolverbindungen, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
ZW19381A1 (en) * | 1980-08-12 | 1983-03-09 | Glaxo Group Ltd | Heterocyclic compounds |
ES504694A0 (es) * | 1980-08-12 | 1982-11-01 | Glaxo Group Ltd | Procedimiento para la preparacion de derivados del indol. |
IT1170387B (it) * | 1982-06-07 | 1987-06-03 | Glaxo Group Ltd | Composti eterociclici, procedimento per prepararli e composizioni farmaceutiche che li contengono |
GB8332435D0 (en) * | 1983-12-06 | 1984-01-11 | Glaxo Group Ltd | Chemical compounds |
GB8332434D0 (en) * | 1983-12-06 | 1984-01-11 | Glaxo Group Ltd | Production of chemical compounds |
-
1984
- 1984-08-01 GB GB848419575A patent/GB8419575D0/en active Pending
-
1985
- 1985-07-26 GR GR851850A patent/GR851850B/el unknown
- 1985-07-30 CH CH3296/85A patent/CH666026A5/fr not_active IP Right Cessation
- 1985-07-30 JO JO19851379A patent/JO1379B1/en active
- 1985-07-31 HU HU852945A patent/HU201738B/hu unknown
- 1985-07-31 IS IS3034A patent/IS1430B6/is unknown
- 1985-08-01 MX MX8273A patent/MX159672A/es unknown
- 1985-08-01 DE DE19853527648 patent/DE3527648A1/de active Granted
- 1985-08-01 IL IL75986A patent/IL75986A/xx not_active IP Right Cessation
- 1985-08-01 NL NLAANVRAGE8502171,A patent/NL188642C/xx not_active IP Right Cessation
- 1985-08-01 ES ES545810A patent/ES8700234A1/es not_active Expired
- 1985-08-01 UA UA3935745A patent/UA6329A1/uk unknown
- 1985-08-01 AU AU45689/85A patent/AU573878B2/en not_active Expired
- 1985-08-01 KR KR1019850005553A patent/KR930003759B1/ko not_active IP Right Cessation
- 1985-08-01 LU LU86032A patent/LU86032A1/fr active Protection Beyond IP Right Term
- 1985-08-01 PL PL1985254800A patent/PL146005B1/pl unknown
- 1985-08-01 SU SU853935745A patent/SU1498386A3/ru active
- 1985-08-01 FI FI852969A patent/FI78466C/fi not_active IP Right Cessation
- 1985-08-01 LU LU88266C patent/LU88266I2/xx unknown
- 1985-08-01 SE SE8503680A patent/SE452460B/sv not_active IP Right Cessation
- 1985-08-01 CA CA000487992A patent/CA1241004A/fr not_active Expired
- 1985-08-01 ZA ZA855818A patent/ZA855818B/xx unknown
- 1985-08-01 DK DK351185A patent/DK158942C/da not_active IP Right Cessation
- 1985-08-01 JP JP60168664A patent/JPH0623197B2/ja not_active Expired - Lifetime
- 1985-08-01 NZ NZ212948A patent/NZ212948A/xx unknown
- 1985-08-01 AT AT0226685A patent/AT386196B/de not_active IP Right Cessation
- 1985-08-01 PT PT80900A patent/PT80900B/pt unknown
- 1985-08-01 BE BE0/215426A patent/BE903006A/fr not_active IP Right Cessation
- 1985-08-01 PH PH32599A patent/PH22850A/en unknown
- 1985-08-01 NO NO853046A patent/NO164653C/no not_active IP Right Cessation
- 1985-08-01 FR FR8511790A patent/FR2568571B1/fr not_active Expired
- 1985-08-01 IT IT8548435A patent/IT1207325B/it active Protection Beyond IP Right Term
- 1985-08-01 EG EG460/85A patent/EG17283A/xx active
- 1985-08-01 ZW ZW124/85A patent/ZW12485A1/xx unknown
- 1985-08-01 MA MA20725A patent/MA20499A1/fr unknown
- 1985-08-01 IE IE191885A patent/IE58122B1/en not_active IP Right Cessation
-
1986
- 1986-02-14 ES ES552047A patent/ES8801204A1/es not_active Expired
- 1986-10-22 PH PH34399A patent/PH24117A/en unknown
-
1987
- 1987-03-31 ES ES557481A patent/ES8801789A1/es not_active Expired
- 1987-03-31 ES ES557480A patent/ES8801788A1/es not_active Expired
- 1987-03-31 ES ES557483A patent/ES8801790A1/es not_active Expired
- 1987-03-31 ES ES557482A patent/ES8801900A1/es not_active Expired
-
1988
- 1988-12-16 MX MX1422188A patent/MX14221A/es unknown
-
1989
- 1989-02-07 KE KE3858A patent/KE3858A/xx unknown
- 1989-03-01 US US07/317,682 patent/US5037845A/en not_active Expired - Lifetime
- 1989-04-20 HK HK332/89A patent/HK33289A/xx not_active IP Right Cessation
- 1989-11-17 DO DO1989004759A patent/DOP1989004759A/es unknown
-
1991
- 1991-12-23 SK SK4041-91A patent/SK277952B6/sk unknown
- 1991-12-23 CZ CS914041A patent/CZ280530B6/cs not_active IP Right Cessation
-
1993
- 1993-06-11 NL NL930065C patent/NL930065I2/nl unknown
-
1994
- 1994-05-26 EC EC1994001096A patent/ECSP941096A/es unknown
- 1994-11-09 NO NO1994023C patent/NO1994023I1/no unknown
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
SK404191A3 (en) | Indole derivatives, method of their production and pharmaceutical preparation with their contents | |
US4816470A (en) | Heterocyclic compounds | |
GB2162522A (en) | An indole derivative | |
JP2941309B2 (ja) | 化合物 | |
JPH01207288A (ja) | インドール誘導体 | |
JPS62228056A (ja) | 化学的化合物 | |
NL8403719A (nl) | Chemische verbindingen. | |
KR20050047552A (ko) | 베타-2 작용제로서의 인돌 유도체 | |
JPH0148896B2 (fr) | ||
NZ197998A (en) | 5-amino(methyl)-1h-indol-3-ylalkaneamines | |
CH667454A5 (fr) | Derives d'indoles. | |
EP0227241B1 (fr) | Dérivés cétosulfone d'indole et d'indazole médicinals | |
US20110009379A1 (en) | Indolinone compound | |
US4980368A (en) | Tryptamine compounds, and methods of cerebrovascular treatment therewith | |
EP1159268A1 (fr) | Indols benzoyles n-substitues comme agents oestrogenes | |
US4528299A (en) | 1-(2,3-Dimethyl-4-methoxyphenyl)-2-methyl-3-(1-pyrrolidinyl)-1-propanone and anti-spastic use thereof | |
JPH0764843B2 (ja) | 新規化合物,その製法及びそれを含む医薬組成物 | |
AU596494B2 (en) | 1-((4-morpholinyl)alkyl)-1h-indoles useful as analgesics and preparation thereof | |
HU211635A9 (en) | Pharmaceutically useful bicyclolactam derivative | |
JPS6022711B2 (ja) | トランス−デカハイドロキノリン誘導体,その製造法,及びそれを含む医薬 | |
JPS58159468A (ja) | 新規な1位置換3−アミノインダゾ−ル誘導体およびその製造法 |