IT1036004B - Acidt 3 indolil adetoidrossamici - Google Patents

Acidt 3 indolil adetoidrossamici

Info

Publication number
IT1036004B
IT1036004B IT51749/68A IT5174968A IT1036004B IT 1036004 B IT1036004 B IT 1036004B IT 51749/68 A IT51749/68 A IT 51749/68A IT 5174968 A IT5174968 A IT 5174968A IT 1036004 B IT1036004 B IT 1036004B
Authority
IT
Italy
Prior art keywords
adetohydroxamics
acidt
indolyl
indolyl adetohydroxamics
Prior art date
Application number
IT51749/68A
Other languages
English (en)
Inventor
Martel Li Eiorado Arrigoni
Martiis F De
T Tamietto
Original Assignee
Abc Ist Biolog Chem Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abc Ist Biolog Chem Spa filed Critical Abc Ist Biolog Chem Spa
Priority to IT51749/68A priority Critical patent/IT1036004B/it
Priority to NL6810284A priority patent/NL6810284A/xx
Priority to US822320A priority patent/US3624103A/en
Priority to BE140122A priority patent/BE810092Q/xx
Application granted granted Critical
Publication of IT1036004B publication Critical patent/IT1036004B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/22—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an aralkyl radical attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an alkyl or cycloalkyl radical attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D209/26—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals with an acyl radical attached to the ring nitrogen atom
    • C07D209/28—1-(4-Chlorobenzoyl)-2-methyl-indolyl-3-acetic acid, substituted in position 5 by an oxygen or nitrogen atom; Esters thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Indole Compounds (AREA)
IT51749/68A 1968-05-21 1968-05-21 Acidt 3 indolil adetoidrossamici IT1036004B (it)

Priority Applications (4)

Application Number Priority Date Filing Date Title
IT51749/68A IT1036004B (it) 1968-05-21 1968-05-21 Acidt 3 indolil adetoidrossamici
NL6810284A NL6810284A (it) 1968-05-21 1968-07-19
US822320A US3624103A (en) 1968-05-21 1969-05-06 3-indoleacetohydroxamic acids
BE140122A BE810092Q (fr) 1968-05-21 1974-01-23 Acides 3-indoleacetohydroxamiques

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT51749/68A IT1036004B (it) 1968-05-21 1968-05-21 Acidt 3 indolil adetoidrossamici

Publications (1)

Publication Number Publication Date
IT1036004B true IT1036004B (it) 1979-10-30

Family

ID=11275666

Family Applications (1)

Application Number Title Priority Date Filing Date
IT51749/68A IT1036004B (it) 1968-05-21 1968-05-21 Acidt 3 indolil adetoidrossamici

Country Status (4)

Country Link
US (1) US3624103A (it)
BE (1) BE810092Q (it)
IT (1) IT1036004B (it)
NL (1) NL6810284A (it)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4186133A (en) * 1978-02-23 1980-01-29 Istituto Biologico Chemioterapico "Abc" S.P.A. Process for the preparation of an indole-3-acetohydroxamic acid
IT1212372B (it) * 1979-09-26 1989-11-22 Abc Ist Biolog Chem Spa Composizioni farmaceutiche ad atti vita' antiulcera contenenti un derivato dell'acido acetoidrossamico
PT72878B (en) * 1980-04-24 1983-03-29 Merck & Co Inc Process for preparing mannich-base hydroxamic acid pro-drugs for the improved delivery of non-steroidal anti-inflammatory agents
IT1144692B (it) * 1981-04-03 1986-10-29 Unibios Spa Nuovo procedimento per la preparazione dell'acido 1-p-clorobenzoil-2-metil-5-metossi-2-indolacetoidrossammico
GB8332435D0 (en) * 1983-12-06 1984-01-11 Glaxo Group Ltd Chemical compounds
GB8419575D0 (en) * 1984-08-01 1984-09-05 Glaxo Group Ltd Chemical compounds
US5112868A (en) * 1988-05-19 1992-05-12 Warner-Lambert Company Hydroxamate derivatives of selected nonsteroidal antiinflammatory acyl residues having cyclooxygenase and 5-lipoxygenase inhibition
US4943587A (en) * 1988-05-19 1990-07-24 Warner-Lambert Company Hydroxamate derivatives of selected nonsteroidal antiinflammatory acyl residues and their use for cyclooxygenase and 5-lipoxygenase inhibition
IL109309A (en) * 1993-04-16 2000-06-29 Lilly Co Eli 1-H-indole-3-acetic acid hydrazide SPLA2 inhibitors and pharmaceutical compositions containing them
HUT72048A (en) * 1994-04-01 1996-03-28 Lilly Co Eli 1h-indole-3-glyoxylamide spla2 inhibitors and pharmaceutical compositions containing these compounds
US5641800A (en) * 1994-07-21 1997-06-24 Eli Lilly And Company 1H-indole-1-functional sPLA2 inhibitors
US6214876B1 (en) 1994-07-21 2001-04-10 Eli Lilly And Company Indene-1-acetamide sPLA2 inhibitors
ES2208935T3 (es) 1996-08-01 2004-06-16 Merckle Gmbh Acidos acil-pirrol-dicarboxilicos y acidos acil-indol-dicarboxilicos, asi como sus derivados como inhibidores de la fosfolipasa a2 citosolica.
SE0301446D0 (sv) 2003-05-16 2003-05-16 Astrazeneca Ab New Compounds
SE0402284D0 (sv) * 2004-09-21 2004-09-21 Astrazeneca Ab New heterocyclic amides
EP1683521A1 (en) * 2005-01-21 2006-07-26 Centre National De La Recherche Scientifique (Cnrs) Peptide deformylase inhibitors, their use, and pharmaceutical compositions containing the same
AR058705A1 (es) * 2005-12-23 2008-02-20 Astrazeneca Ab Compuestos de bencimidazol como inhibidores del receptor vaniloide 1 (vr1)
TWI433839B (zh) * 2006-08-11 2014-04-11 Neomed Inst 新穎的苯并咪唑衍生物290
EP3750878B1 (en) * 2019-06-14 2025-05-14 Vivoryon Therapeutics N.V. Heteroaromatic inhibitors of astacin proteinases

Also Published As

Publication number Publication date
NL6810284A (it) 1969-11-25
BE810092Q (fr) 1974-05-16
US3624103A (en) 1971-11-30

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