SK281143B6 - Chimérická monoklonálna protilátka, expresné vektory a farmaceutický prostriedok - Google Patents

Chimérická monoklonálna protilátka, expresné vektory a farmaceutický prostriedok Download PDF

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Publication number
SK281143B6
SK281143B6 SK360-99A SK36099A SK281143B6 SK 281143 B6 SK281143 B6 SK 281143B6 SK 36099 A SK36099 A SK 36099A SK 281143 B6 SK281143 B6 SK 281143B6
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SK
Slovakia
Prior art keywords
human
antibody
regions
region
antibodies
Prior art date
Application number
SK360-99A
Other languages
English (en)
Slovak (sk)
Inventor
Mary M. Bendig
Cathrine A. Kettleborough
Jos Saldanha
Original Assignee
Merck Patent Gesellschaft Mit Beschr�Nkter Haftung
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gesellschaft Mit Beschr�Nkter Haftung filed Critical Merck Patent Gesellschaft Mit Beschr�Nkter Haftung
Publication of SK281143B6 publication Critical patent/SK281143B6/sk

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2863Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00Reverse transcribing RNA viruses
    • C12N2740/00011Details
    • C12N2740/10011Retroviridae
    • C12N2740/16011Human Immunodeficiency Virus, HIV
    • C12N2740/16211Human Immunodeficiency Virus, HIV concerning HIV gagpol
    • C12N2740/16222New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/867Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof involving immunoglobulin or antibody produced via recombinant dna technology

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Virology (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
SK360-99A 1991-03-06 1992-03-04 Chimérická monoklonálna protilátka, expresné vektory a farmaceutický prostriedok SK281143B6 (sk)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP91103389 1991-03-06
PCT/EP1992/000480 WO1992015683A1 (en) 1991-03-06 1992-03-04 Humanized and chimeric monoclonal antibodies

Publications (1)

Publication Number Publication Date
SK281143B6 true SK281143B6 (sk) 2000-12-11

Family

ID=8206486

Family Applications (2)

Application Number Title Priority Date Filing Date
SK360-99A SK281143B6 (sk) 1991-03-06 1992-03-04 Chimérická monoklonálna protilátka, expresné vektory a farmaceutický prostriedok
SK3327-92A SK281142B6 (sk) 1991-03-06 1992-03-04 Humanizovaná monoklonálna protilátka, expresné vektory a farmaceutický prostriedok

Family Applications After (1)

Application Number Title Priority Date Filing Date
SK3327-92A SK281142B6 (sk) 1991-03-06 1992-03-04 Humanizovaná monoklonálna protilátka, expresné vektory a farmaceutický prostriedok

Country Status (19)

Country Link
US (1) US5558864A (https=)
EP (2) EP0531472B1 (https=)
JP (1) JP3854306B2 (https=)
KR (1) KR100240308B1 (https=)
AT (1) ATE247168T1 (https=)
AU (1) AU658396B2 (https=)
CA (1) CA2082160C (https=)
CZ (2) CZ283717B6 (https=)
DE (1) DE69233153T2 (https=)
DK (1) DK0531472T3 (https=)
ES (1) ES2204890T3 (https=)
HU (1) HU219537B (https=)
IE (1) IE920705A1 (https=)
MX (1) MX9201016A (https=)
PT (1) PT100195B (https=)
SK (2) SK281143B6 (https=)
TW (1) TW222279B (https=)
WO (1) WO1992015683A1 (https=)
ZA (1) ZA921661B (https=)

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