SI2671882T1 - Pirolo(2,3-b)piridin-4-il-amini in pirolo(2m3-b)pirimidin-4-il-amini kot inhibitorji janus kinaze - Google Patents
Pirolo(2,3-b)piridin-4-il-amini in pirolo(2m3-b)pirimidin-4-il-amini kot inhibitorji janus kinaze Download PDFInfo
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- SI2671882T1 SI2671882T1 SI200532196T SI200532196T SI2671882T1 SI 2671882 T1 SI2671882 T1 SI 2671882T1 SI 200532196 T SI200532196 T SI 200532196T SI 200532196 T SI200532196 T SI 200532196T SI 2671882 T1 SI2671882 T1 SI 2671882T1
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- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
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- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P5/00—Drugs for disorders of the endocrine system
- A61P5/14—Drugs for disorders of the endocrine system of the thyroid hormones, e.g. T3, T4
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
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- Bioinformatics & Cheminformatics (AREA)
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- Virology (AREA)
- Diabetes (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Molecular Biology (AREA)
- Dermatology (AREA)
- Rheumatology (AREA)
- Endocrinology (AREA)
- Hematology (AREA)
- Pain & Pain Management (AREA)
- Obesity (AREA)
- AIDS & HIV (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pulmonology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biotechnology (AREA)
- Emergency Medicine (AREA)
- Transplantation (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Claims (10)
- Pirolo[2,3-b]piridin-4-il-amini in pirolo[2m3-b]pirimidin-4-il-amini kot inhibitorji j anus kinaze Patentni zahtevki1. Farmacevtski sestavek za uporabo v zdravljenju kožnih motenj v pacientu značilen po tem, daje sestavek administriran topikalno, kjer omenjeni sestavek vsebuje spojino, kije 3-{(3R,4R)-4-metil-3-[metil-(7H-pirolo[2,3- djpirimidin-4-il)amino]-piperidin-l-il}-3-okso-propionitril ali njena farmacevtsko sprejemljiva sol.
- 2. Sestavek za uporabo po zahtevku 1, kjer je omenjena kožna motnja atopični dermatitis ali psoriaza.
- 3. Sestavek za uporabo po zahtevku 1, kjer je omenjena kožna motnja preobčutljivost kože, draženje kože, kožni izpuščaj, kontaktni dermatitis ali kontaktna alergijska preobčutljivost kože.
- 4. Sestavek za uporabo po zahtevku 1, kjer omenjena topikalna administracija obsega transdermalno administracijo.
- 5. Sestavek za uporabo po zahtevku 1, ki je v obliki transdermalnega obliža, mazila, losjona, kreme ali gela.
- 6. Spojina za uporabo v zdravljenju kožnih motenj v pacientu, značilen po tem, da je spojina administriran topikalno, kjer je spojina 3-{(3R,4R)-4-metil-3-[metil-(7H-pirolo[2,3- d]pirimidin-4-il)amino]-piperidin-l-il}-3-okso-propionitril ali njena farmacevtsko sprejemljiva sol.
- 7. Spojina za uporabo po zahtevku 6, kjer je omenjena kožna motnja atopični dermatitis ali psoriaza.
- 8. Spojina za uporabo po zahtevku 6, kjer je omenjena kožna motnja preobčutljivost kože, draženje kože, kožni izpuščaj, kontaktni dermatitis ali kontaktna alergijska preobčutljivost kože.
- 9. Spojina za uporabo po zahtevku 6, kjer omenjena topikalna administracija obsega transdermalno administracijo.
- 10. Spojina za uporabo po zahtevku 6, kjer je omenjena spojina za administracijo v obliki transdermalnega obliža, mazila, losjona, kreme ali gela.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US63847404P | 2004-12-22 | 2004-12-22 | |
US72628905P | 2005-10-13 | 2005-10-13 | |
EP13171524.5A EP2671882B1 (en) | 2004-12-22 | 2005-12-21 | pyrrolo[2,3-b]pyridin-4-yl-amines and pyrrolo[2m3-b]pyrimidin-4-yl-amines as janus kinase inhibitors |
Publications (1)
Publication Number | Publication Date |
---|---|
SI2671882T1 true SI2671882T1 (sl) | 2018-06-29 |
Family
ID=36602272
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SI200532196T SI2671882T1 (sl) | 2004-12-22 | 2005-12-21 | Pirolo(2,3-b)piridin-4-il-amini in pirolo(2m3-b)pirimidin-4-il-amini kot inhibitorji janus kinaze |
Country Status (19)
Country | Link |
---|---|
US (7) | US7335667B2 (sl) |
EP (2) | EP1828181B1 (sl) |
JP (2) | JP5048514B2 (sl) |
AR (1) | AR054416A1 (sl) |
CA (1) | CA2592119C (sl) |
CY (1) | CY1120257T1 (sl) |
DK (1) | DK2671882T3 (sl) |
ES (2) | ES2666819T3 (sl) |
HK (1) | HK1108443A1 (sl) |
HR (1) | HRP20180578T1 (sl) |
HU (1) | HUE037435T2 (sl) |
LT (1) | LT2671882T (sl) |
ME (1) | ME03017B (sl) |
PL (1) | PL2671882T3 (sl) |
PT (1) | PT2671882T (sl) |
RS (1) | RS57302B1 (sl) |
SI (1) | SI2671882T1 (sl) |
TW (2) | TW201414732A (sl) |
WO (1) | WO2006069080A2 (sl) |
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