MA51829A - Inhibiteurs de la voie jak1 pour le traitement de troubles liés aux cytokines - Google Patents
Inhibiteurs de la voie jak1 pour le traitement de troubles liés aux cytokinesInfo
- Publication number
- MA51829A MA51829A MA051829A MA51829A MA51829A MA 51829 A MA51829 A MA 51829A MA 051829 A MA051829 A MA 051829A MA 51829 A MA51829 A MA 51829A MA 51829 A MA51829 A MA 51829A
- Authority
- MA
- Morocco
- Prior art keywords
- jak1
- cytokine
- treatment
- related disorders
- inhibitors
- Prior art date
Links
- 101000997835 Homo sapiens Tyrosine-protein kinase JAK1 Proteins 0.000 title 1
- 102100033438 Tyrosine-protein kinase JAK1 Human genes 0.000 title 1
- 239000003112 inhibitor Substances 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
- A61K31/4155—1,2-Diazoles non condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
- A61K31/437—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system containing a five-membered ring having nitrogen as a ring hetero atom, e.g. indolizine, beta-carboline
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/506—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201862710446P | 2018-02-16 | 2018-02-16 | |
US201862631825P | 2018-02-18 | 2018-02-18 |
Publications (1)
Publication Number | Publication Date |
---|---|
MA51829A true MA51829A (fr) | 2020-12-23 |
Family
ID=65529906
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MA051829A MA51829A (fr) | 2018-02-16 | 2019-02-14 | Inhibiteurs de la voie jak1 pour le traitement de troubles liés aux cytokines |
Country Status (20)
Country | Link |
---|---|
US (3) | US11103510B2 (fr) |
EP (1) | EP3752146A1 (fr) |
JP (2) | JP2021513981A (fr) |
KR (1) | KR20200128043A (fr) |
CN (1) | CN111936135A (fr) |
AU (1) | AU2019221667A1 (fr) |
BR (3) | BR122023022247A2 (fr) |
CA (1) | CA3091339A1 (fr) |
CL (1) | CL2020002102A1 (fr) |
CO (1) | CO2020011388A2 (fr) |
EC (1) | ECSP20057643A (fr) |
IL (2) | IL276725B1 (fr) |
MA (1) | MA51829A (fr) |
MX (2) | MX2020008521A (fr) |
PE (1) | PE20212186A1 (fr) |
PH (1) | PH12020551251A1 (fr) |
SG (1) | SG11202007805SA (fr) |
TW (2) | TWI799513B (fr) |
UA (1) | UA127519C2 (fr) |
WO (1) | WO2019161098A1 (fr) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN107936039A (zh) | 2012-11-01 | 2018-04-20 | 因赛特公司 | 作为jak抑制剂的三环稠合噻吩衍生物 |
EP3752146A1 (fr) | 2018-02-16 | 2020-12-23 | Incyte Corporation | Inhibiteurs de la voie jak1 pour le traitement de troubles liés aux cytokines |
WO2019191679A1 (fr) | 2018-03-30 | 2019-10-03 | Incyte Corporation | Biomarqueurs pour maladie cutanée inflammatoire |
MA52208A (fr) | 2018-04-13 | 2021-02-17 | Incyte Corp | Biomarqueurs pour une maladie du greffon contre l'hôte |
CA3117969A1 (fr) | 2018-10-31 | 2020-05-07 | Incyte Corporation | Polytherapie pour le traitement de maladies hematologiques |
CN114007621A (zh) | 2019-03-05 | 2022-02-01 | 因赛特公司 | 用于治疗慢性肺同种异体移植物功能障碍的jak1途径抑制剂 |
MX2022001596A (es) * | 2019-08-08 | 2022-03-11 | Rigel Pharmaceuticals Inc | Compuestos y metodos para tratar sindrome de liberacion de citocinas. |
US11992490B2 (en) | 2019-10-16 | 2024-05-28 | Incyte Corporation | Use of JAK1 inhibitors for the treatment of cutaneous lupus erythematosus and Lichen planus (LP) |
MX2023006542A (es) * | 2020-12-08 | 2023-08-25 | Incyte Corp | Inhibidores de la vía cinasa jano 1 (jak1) para el tratamiento del vitiligo. |
IL308216A (en) * | 2021-05-03 | 2024-01-01 | Incyte Corp | Jak1 pathway inhibitors for the treatment of prurigo nodularis |
WO2024032527A1 (fr) * | 2022-08-08 | 2024-02-15 | 石药集团中奇制药技术(石家庄)有限公司 | Utilisation d'un composé contenant un hétéroaryle tricyclique |
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EP3752146A1 (fr) | 2018-02-16 | 2020-12-23 | Incyte Corporation | Inhibiteurs de la voie jak1 pour le traitement de troubles liés aux cytokines |
WO2019191679A1 (fr) | 2018-03-30 | 2019-10-03 | Incyte Corporation | Biomarqueurs pour maladie cutanée inflammatoire |
AU2019245420A1 (en) | 2018-03-30 | 2020-11-12 | Incyte Corporation | Treatment of hidradenitis suppurativa using JAK inhibitors |
MA52208A (fr) | 2018-04-13 | 2021-02-17 | Incyte Corp | Biomarqueurs pour une maladie du greffon contre l'hôte |
EP3941474A2 (fr) | 2019-03-19 | 2022-01-26 | Incyte Corporation | Biomarqueurs pour le vitiligo |
PE20231102A1 (es) | 2020-06-02 | 2023-07-19 | Incyte Corp | Procesos para preparar un inhibidor de jak1 |
MX2023006638A (es) | 2020-12-04 | 2023-08-22 | Incyte Corp | Inhibidor de la cinasa janus (jak) con un análogo de la vitamina d para el tratamiento de enfermedades de la piel. |
MX2023006542A (es) | 2020-12-08 | 2023-08-25 | Incyte Corp | Inhibidores de la vía cinasa jano 1 (jak1) para el tratamiento del vitiligo. |
IL308216A (en) | 2021-05-03 | 2024-01-01 | Incyte Corp | Jak1 pathway inhibitors for the treatment of prurigo nodularis |
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2019
- 2019-02-14 EP EP19707655.7A patent/EP3752146A1/fr active Pending
- 2019-02-14 BR BR122023022247-4A patent/BR122023022247A2/pt unknown
- 2019-02-14 CA CA3091339A patent/CA3091339A1/fr active Pending
- 2019-02-14 PE PE2020001231A patent/PE20212186A1/es unknown
- 2019-02-14 KR KR1020207026669A patent/KR20200128043A/ko unknown
- 2019-02-14 AU AU2019221667A patent/AU2019221667A1/en active Pending
- 2019-02-14 MX MX2020008521A patent/MX2020008521A/es unknown
- 2019-02-14 IL IL276725A patent/IL276725B1/en unknown
- 2019-02-14 US US16/276,157 patent/US11103510B2/en active Active
- 2019-02-14 BR BR112020016628-6A patent/BR112020016628A2/pt unknown
- 2019-02-14 CN CN201980024450.5A patent/CN111936135A/zh active Pending
- 2019-02-14 SG SG11202007805SA patent/SG11202007805SA/en unknown
- 2019-02-14 MA MA051829A patent/MA51829A/fr unknown
- 2019-02-14 UA UAA202005910A patent/UA127519C2/uk unknown
- 2019-02-14 JP JP2020543559A patent/JP2021513981A/ja active Pending
- 2019-02-14 BR BR122023022189-3A patent/BR122023022189A2/pt unknown
- 2019-02-14 WO PCT/US2019/018066 patent/WO2019161098A1/fr unknown
- 2019-02-14 IL IL311485A patent/IL311485A/en unknown
- 2019-02-15 TW TW108105190A patent/TWI799513B/zh active
- 2019-02-15 TW TW112110278A patent/TW202342026A/zh unknown
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2020
- 2020-08-14 PH PH12020551251A patent/PH12020551251A1/en unknown
- 2020-08-14 CL CL2020002102A patent/CL2020002102A1/es unknown
- 2020-08-14 MX MX2023003392A patent/MX2023003392A/es unknown
- 2020-09-15 EC ECSENADI202057643A patent/ECSP20057643A/es unknown
- 2020-09-15 CO CONC2020/0011388A patent/CO2020011388A2/es unknown
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2021
- 2021-07-19 US US17/379,336 patent/US11833152B2/en active Active
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2023
- 2023-10-23 US US18/382,939 patent/US20240156818A1/en active Pending
- 2023-11-01 JP JP2023187800A patent/JP2024023213A/ja active Pending
Also Published As
Publication number | Publication date |
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UA127519C2 (uk) | 2023-09-20 |
BR122023022189A2 (pt) | 2024-02-20 |
CN111936135A (zh) | 2020-11-13 |
AU2019221667A1 (en) | 2020-10-01 |
JP2021513981A (ja) | 2021-06-03 |
IL276725B1 (en) | 2024-05-01 |
MX2023003392A (es) | 2023-06-16 |
MX2020008521A (es) | 2020-12-03 |
BR122023022247A2 (pt) | 2024-02-20 |
BR112020016628A2 (pt) | 2020-12-15 |
PH12020551251A1 (en) | 2021-05-17 |
TW202000203A (zh) | 2020-01-01 |
US11833152B2 (en) | 2023-12-05 |
KR20200128043A (ko) | 2020-11-11 |
EP3752146A1 (fr) | 2020-12-23 |
PE20212186A1 (es) | 2021-11-11 |
SG11202007805SA (en) | 2020-09-29 |
TW202342026A (zh) | 2023-11-01 |
TWI799513B (zh) | 2023-04-21 |
WO2019161098A1 (fr) | 2019-08-22 |
US20190255053A1 (en) | 2019-08-22 |
IL276725A (en) | 2020-09-30 |
CO2020011388A2 (es) | 2020-12-10 |
ECSP20057643A (es) | 2020-12-31 |
US11103510B2 (en) | 2021-08-31 |
CA3091339A1 (fr) | 2019-08-22 |
US20220040187A1 (en) | 2022-02-10 |
IL311485A (en) | 2024-05-01 |
CL2020002102A1 (es) | 2021-01-29 |
US20240156818A1 (en) | 2024-05-16 |
JP2024023213A (ja) | 2024-02-21 |
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