SI0690864T1 - Crystalline ceftiofur free acid - Google Patents

Crystalline ceftiofur free acid

Info

Publication number
SI0690864T1
SI0690864T1 SI9430374T SI9430374T SI0690864T1 SI 0690864 T1 SI0690864 T1 SI 0690864T1 SI 9430374 T SI9430374 T SI 9430374T SI 9430374 T SI9430374 T SI 9430374T SI 0690864 T1 SI0690864 T1 SI 0690864T1
Authority
SI
Slovenia
Prior art keywords
free acid
pct
ceftiofur free
crystalline ceftiofur
date sep
Prior art date
Application number
SI9430374T
Other languages
English (en)
Inventor
Michael J Dunn
Michael S Bergren
Gregory E Hardee
Kenneth Paul Shephard
Robert S Chao
Jeffrey L Havens
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of SI0690864T1 publication Critical patent/SI0690864T1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • Virology (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
SI9430374T 1993-03-12 1994-03-07 Crystalline ceftiofur free acid SI0690864T1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US3329193A 1993-03-12 1993-03-12
PCT/US1994/001862 WO1994020505A1 (en) 1993-03-12 1994-03-07 Crystalline ceftiofur free acid
EP94910721A EP0690864B1 (en) 1993-03-12 1994-03-07 Crystalline ceftiofur free acid

Publications (1)

Publication Number Publication Date
SI0690864T1 true SI0690864T1 (en) 2001-10-31

Family

ID=21869579

Family Applications (1)

Application Number Title Priority Date Filing Date
SI9430374T SI0690864T1 (en) 1993-03-12 1994-03-07 Crystalline ceftiofur free acid

Country Status (31)

Country Link
US (1) US5721359A (cs)
EP (1) EP0690864B1 (cs)
JP (1) JP3852946B2 (cs)
KR (1) KR100296810B1 (cs)
CN (1) CN1055090C (cs)
AT (1) ATE202109T1 (cs)
AU (1) AU694419B2 (cs)
BR (1) BR1101034A (cs)
CA (1) CA2155322C (cs)
CZ (1) CZ289332B6 (cs)
DE (2) DE69427469T2 (cs)
DK (1) DK0690864T3 (cs)
ES (1) ES2157254T3 (cs)
FI (1) FI120307B (cs)
FR (1) FR05C0045I2 (cs)
GR (1) GR3036514T3 (cs)
HU (1) HU222244B1 (cs)
IL (1) IL108910A (cs)
LU (1) LU91206I2 (cs)
LV (1) LV12889B (cs)
NL (1) NL300208I2 (cs)
NO (2) NO313199B1 (cs)
NZ (1) NZ263002A (cs)
PL (1) PL184611B1 (cs)
PT (1) PT690864E (cs)
RU (1) RU2136685C1 (cs)
SI (1) SI0690864T1 (cs)
SK (1) SK283674B6 (cs)
TW (1) TW267170B (cs)
WO (1) WO1994020505A1 (cs)
ZA (1) ZA941586B (cs)

Families Citing this family (73)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5736151A (en) * 1996-12-09 1998-04-07 Pharmacia & Upjohn Company Antibiotic oil suspensions
US6074657A (en) * 1997-03-20 2000-06-13 Pharmacia & Upjohn Company Administration of an injectable antibiotic in the ear of an animal
US7829100B2 (en) * 2000-09-12 2010-11-09 Teagarden Dirk L Pharmaceutical composition having modified carrier
BRPI0113372B8 (pt) * 2000-09-12 2021-10-13 Pah P&U Llc composição veterinária com veículo modificado e ceftiofur
KR100423895B1 (ko) * 2001-02-19 2004-03-24 주식회사 엘지생명과학 셉티오퍼 하이드로클로라이드의 현탁제 조성물
WO2003006441A1 (en) * 2001-07-10 2003-01-23 Pharmacia & Upjohn Company Crystalline thiazine oxazolidinones
DK3168218T3 (en) * 2001-08-15 2019-01-14 Pharmacia & Upjohn Co Llc Crystalline comprising an L-malic acid salt of N- [2- (DIETHYLAMINO) ETHYL] -5 - [(5-FLUOR-1,2-DIHYDRO-2-OXO-3H-INDOL-3-YLIDE) METHYL] -2,4 -DIMETHYL-1H-PYRROL-3-CARBOXAMIDE FOR USE AS A MEDICINE
ATE343980T1 (de) 2002-03-21 2006-11-15 Pharmacia & Upjohn Co Llc Verfahren zur verabreichung von injizierbarem antibiotikum im ohr eines tieres
US20040022815A1 (en) * 2002-08-05 2004-02-05 Orchid Health Care Novel pharmaceutical composition of ceftiofur
KR20040015622A (ko) * 2002-08-13 2004-02-19 대한뉴팜(주) 세프티오푸르나트륨을 활성성분으로 함유하는 현탁주사액조성물
US20040115822A1 (en) * 2002-09-12 2004-06-17 Schapaugh Randal Lee Methods of measuring the dissolution rate of an analyte in a non-aqueous liquid composition
US7659061B2 (en) * 2002-11-19 2010-02-09 Pharmacia & Upjohn Company Pharmaceutical compositions having a modified vehicle
US20040115837A1 (en) * 2002-11-27 2004-06-17 Schapaugh Randal Lee Methods of measuring the dissolution rate of an analyte in a non-aqueous liquid composition
US7842791B2 (en) * 2002-12-19 2010-11-30 Nancy Jean Britten Dispersible pharmaceutical compositions
US7531650B2 (en) * 2003-03-27 2009-05-12 Basilea Pharmaceutica Ag Cephalosporin salts in crystalline form
CZ23090U1 (cs) * 2004-03-25 2011-12-19 Astellas Pharma Inc. Kompozice pevného farmaceutického prípravku solifenacinu nebo jeho soli
US7815939B2 (en) 2005-07-20 2010-10-19 Astellas Pharma Inc. Coated fine particles containing drug for intrabuccally fast disintegrating dosage forms
US8470809B2 (en) * 2005-10-12 2013-06-25 Orchid Chemicals & Pharmaceuticals Limited Crystalline sodium salt of cephalosporin antibiotic
EP1934231A4 (en) * 2005-10-12 2011-10-26 Orchid Chemicals & Pharm Ltd CRYSTALLINE SODIUM SALT OF ANTIBIOTICS BASED ON CEPHALOSPORINE
SA08290520B1 (ar) 2007-08-22 2012-02-22 استرازينيكا ايه بي مشتقات سيكلو بروبيل أميد وتركيبات صيدلية تحتوي عليها لعلاج حالة مرضية سببها مستقبلات هيستامين h3
WO2010036427A1 (en) 2008-06-17 2010-04-01 Brigham Young University Cationic steroid antimicrobial diagnostic, detection, screening and imaging methods
EP2324034A4 (en) * 2008-08-22 2012-05-16 Orchid Chemicals & Pharm Ltd CRYSTALLINE SODIUM SALT OF CEPHALOSPORIN ANTIBIOTIC
EP2367572B1 (en) * 2008-11-19 2018-08-29 Merial, Inc. Formulations comprising ceftiofur and benzyl alcohol
NZ594064A (en) * 2009-01-30 2012-08-31 Glaxosmithkline Llc Crystalline n-{ (1s)-2-amino-1-[(3-fluorophenyl)methyl]ethyl} -5-chloro-4-(4-chloro-1-methyl-1h-pyrazol-5-yl)-2-thiophenecarboxamide hydrochloride
TW201039825A (en) 2009-02-20 2010-11-16 Astrazeneca Ab Cyclopropyl amide derivatives 983
KR20130034009A (ko) * 2010-02-18 2013-04-04 아스트라제네카 아베 시클로프로필 아미드 유도체를 포함하는 고체 형태
KR20130002316A (ko) 2010-02-18 2013-01-07 아스트라제네카 아베 시클로프로필 벤즈아미드 유도체의 신규 결정질 형태
EP2705044A1 (en) * 2011-05-02 2014-03-12 Zoetis Llc Novel cephalosporins useful as antibacterial agents
CN104053458B (zh) 2011-07-20 2016-07-20 布莱阿姆青年大学 包含洗脱塞拉集宁化合物的水凝胶材料
US9603859B2 (en) 2011-09-13 2017-03-28 Brigham Young University Methods and products for increasing the rate of healing of tissue wounds
CN104080459B (zh) 2011-09-13 2018-07-03 布莱阿姆青年大学 用于治疗骨疾病和断骨的组合物
US9694019B2 (en) 2011-09-13 2017-07-04 Brigham Young University Compositions and methods for treating bone diseases and broken bones
MX369385B (es) 2011-09-13 2019-11-07 Univ Brigham Young Productos para cicatrizar heridas tisulares.
UA113298C2 (xx) 2011-12-21 2017-01-10 Композиція для догляду за порожниною рота
CN102584855B (zh) * 2012-02-16 2014-06-25 青岛科技大学 一种改进的头孢噻呋的制备方法
US9533063B1 (en) 2012-03-01 2017-01-03 Brigham Young University Aerosols incorporating ceragenin compounds and methods of use thereof
EP2846634A2 (en) 2012-05-02 2015-03-18 Brigham Young University Ceragenin particulate materials and methods for making same
CA2888259C (en) 2012-10-17 2019-05-28 Brigham Young University Treatment and prevention of mastitis
WO2014087972A1 (ja) * 2012-12-03 2014-06-12 株式会社カネカ 還元型補酵素q10誘導体およびその製造方法
CA2897150C (en) 2013-01-07 2021-07-13 Brigham Young University Methods for reducing cellular proliferation and treating certain diseases
US11524015B2 (en) 2013-03-15 2022-12-13 Brigham Young University Methods for treating inflammation, autoimmune disorders and pain
US10568893B2 (en) 2013-03-15 2020-02-25 Brigham Young University Methods for treating inflammation, autoimmune disorders and pain
CN110420211A (zh) 2013-03-15 2019-11-08 布莱阿姆青年大学 治疗炎症、自身免疫性疾病和疼痛的方法
RU2546675C2 (ru) * 2013-04-11 2015-04-10 Федеральное казённое предприятие "Государственный научно-исследовательский институт химических продуктов" (ФКП "ГосНИИХП") Способ определения степени кристалличности составов на основе дифениламина
US9387215B2 (en) 2013-04-22 2016-07-12 Brigham Young University Animal feed including cationic cholesterol additive and related methods
EP3360858B1 (en) * 2013-09-05 2020-04-29 Mitsubishi Tanabe Pharma Corporation Process for producing an aminopyrrolidine derivative
US11690855B2 (en) 2013-10-17 2023-07-04 Brigham Young University Methods for treating lung infections and inflammation
US20150203527A1 (en) 2014-01-23 2015-07-23 Brigham Young University Cationic steroidal antimicrobials
CA2844321C (en) 2014-02-27 2021-03-16 Brigham Young University Cationic steroidal antimicrobial compounds
US10220045B2 (en) 2014-03-13 2019-03-05 Brigham Young University Compositions and methods for forming stabilized compositions with reduced CSA agglomeration
US9867836B2 (en) 2014-03-13 2018-01-16 Brigham Young University Lavage and/or infusion using CSA compounds for increasing fertility in a mammal
US9931350B2 (en) 2014-03-14 2018-04-03 Brigham Young University Anti-infective and osteogenic compositions and methods of use
US9686966B2 (en) 2014-04-30 2017-06-27 Brigham Young University Methods and apparatus for cleaning or disinfecting a water delivery system
US10441595B2 (en) 2014-06-26 2019-10-15 Brigham Young University Methods for treating fungal infections
US10238665B2 (en) 2014-06-26 2019-03-26 Brigham Young University Methods for treating fungal infections
US10227376B2 (en) 2014-08-22 2019-03-12 Brigham Young University Radiolabeled cationic steroid antimicrobials and diagnostic methods
US10155788B2 (en) 2014-10-07 2018-12-18 Brigham Young University Cationic steroidal antimicrobial prodrug compositions and uses thereof
CN111825717A (zh) * 2014-10-21 2020-10-27 阿瑞雅德制药公司 5-氯-n4-[2-(二甲基磷酰基)苯基]-n2-{2-甲氧基-4-[4-(4-甲基哌嗪-1-基)哌啶-1-基]苯基}嘧啶-2,4-二胺的晶形
WO2016172553A1 (en) 2015-04-22 2016-10-27 Savage Paul B Methods for the synthesis of ceragenins
US10370403B2 (en) 2015-04-22 2019-08-06 Brigham Young University Methods for the synthesis of ceragenins
KR101753842B1 (ko) * 2015-05-12 2017-07-04 한국화학연구원 불화퀴놀론계 항생제를 담지한 서방형 제제 및 이의 제조방법
US9434759B1 (en) 2015-05-18 2016-09-06 Brigham Young University Cationic steroidal antimicrobial compounds and methods of manufacturing such compounds
CN106543203B (zh) * 2015-09-18 2019-07-02 瑞普(天津)生物药业有限公司 一种长效头孢噻呋自由酸晶体的制备方法
CA3011323A1 (en) * 2016-01-22 2017-07-27 Sandoz Ag Crystalline eravacycline bis-hydrochloride
US10226550B2 (en) 2016-03-11 2019-03-12 Brigham Young University Cationic steroidal antimicrobial compositions for the treatment of dermal tissue
KR101898282B1 (ko) * 2016-05-24 2018-09-13 주식회사 고려비엔피 항생제의 서방형 수의학적 조성물 및 이의 제조방법
US10889577B2 (en) 2016-07-07 2021-01-12 Cyclerion Therapeutics, Inc. Solid forms of an sGC stimulator
US10959433B2 (en) 2017-03-21 2021-03-30 Brigham Young University Use of cationic steroidal antimicrobials for sporicidal activity
US11186556B1 (en) * 2018-10-16 2021-11-30 Celgene Corporation Salts of a thiazolidinone compound, solid forms, compositions and methods of use thereof
UA119735C2 (uk) 2018-12-20 2019-07-25 Анатолій Семенович Редер Фармацевтична сполука, спосіб її отримання та застосування як лікарського засобу
US12186328B2 (en) 2019-05-23 2025-01-07 Brigham Young University Use of CSA compounds to stimulate stem cells and hair growth
TW202233625A (zh) * 2020-11-18 2022-09-01 美商傳達治療有限公司 Fgfr抑制劑及其製造及使用方法
CN117229296A (zh) * 2023-09-14 2023-12-15 广东温氏大华农生物科技有限公司 一种头孢噻呋酸晶体及其制备方法与应用

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1207933B (de) * 1962-12-26 1965-12-30 American Home Prod Verfahren zur Herstellung von kristallwasser-freiem D-alpha-Aminobenzylpenicillin
US3489750A (en) * 1967-09-05 1970-01-13 Bristol Myers Co 7-amino-cephalosporanic and decephalosporanic acid derivatives
DK154939C (da) * 1974-12-19 1989-06-12 Takeda Chemical Industries Ltd Analogifremgangsmaade til fremstilling af thiazolylacetamido-cephemforbindelser eller farmaceutisk acceptable salte eller estere deraf
DE2760123C2 (de) * 1976-01-23 1986-04-30 Roussel-Uclaf, Paris 7-Aminothiazolyl-syn-oxyiminoacetamidocephalosporansäuren, ihre Herstellung und sie enthaltende pharmazeutische Zusammensetzungen
GB1532682A (en) * 1976-04-27 1978-11-22 Bristol Myers Co Process for the preparation of cephadroxil
FR2479229B1 (fr) * 1980-03-26 1986-01-17 Clin Midy Nouveaux derives des cephalosporines, leur procede de preparation et les medicaments utilisables comme antibiotiques qui contiennent lesdits derives
IL63968A (en) * 1980-10-01 1985-10-31 Glaxo Group Ltd Form 2 ranitidine hydrochloride,its preparation and pharmaceutical compositions containing it
US4400503A (en) * 1981-10-30 1983-08-23 Eli Lilly And Company Purification of syn-7-[[(2-amino-4-thiazolyl)(methoxyimino) acetyl]amino]-3-methyl-3-cephem-4-carboxylic acid
DE3313818A1 (de) * 1983-04-16 1984-10-18 Hoechst Ag, 6230 Frankfurt Neue kristallmodifikation von ceftazidim
HU196714B (en) * 1984-10-04 1989-01-30 Monsanto Co Process for producing non-aqueous composition comprising somatotropin
IT1181672B (it) * 1984-10-25 1987-09-30 Upjohn Co Cefalosporina alogenidrato cristallino
US4902683A (en) * 1984-10-25 1990-02-20 The Upjohn Company Crystalline cephalosporin hydrohalide salts
FR2585705B1 (fr) * 1985-08-05 1989-01-13 Bristol Myers Co Sels de cephalosporine et compositions injectables
EP0233255B1 (en) * 1985-08-12 1996-05-29 The Upjohn Company Conversion of cephalosporin hydrohalide salt to alkali metal salt
GB8608962D0 (en) * 1986-04-12 1986-05-14 Beecham Group Plc Beta-lactam antibiotics
IT1214587B (it) * 1986-12-23 1990-01-18 Giovanni Bonfanti Metodo per la produzione diprodotti cristallini puri.
DE3871542T2 (de) * 1987-02-02 1992-12-24 Lilly Co Eli Verfahren zur herstellung von ceftazidime-pentahydrat.
DE3869135D1 (de) * 1987-07-29 1992-04-16 Upjohn Co Kontrollierte freisetzung von antibiotika-salzen aus einem implantat.
DE3887691T2 (de) * 1987-11-10 1994-06-09 Upjohn Co Cephalosporin-antibiotika.
US4877782A (en) * 1988-02-16 1989-10-31 The Upjohn Company Zinc ceftiofur complexes

Also Published As

Publication number Publication date
CN1119016A (zh) 1996-03-20
ZA941586B (en) 1995-09-07
SK283674B6 (sk) 2003-11-04
US5721359A (en) 1998-02-24
GR3036514T3 (en) 2001-12-31
CA2155322C (en) 2000-02-29
DE122005000055I2 (de) 2008-06-05
FR05C0045I2 (cs) 2007-08-03
PT690864E (pt) 2001-11-30
JPH08507519A (ja) 1996-08-13
DE122005000055I1 (de) 2006-02-23
NO2005025I1 (no) 2005-12-05
NL300208I1 (nl) 2006-02-01
WO1994020505A1 (en) 1994-09-15
NO2005025I2 (no) 2010-11-22
SK111495A3 (en) 1995-12-06
AU6351094A (en) 1994-09-26
ATE202109T1 (de) 2001-06-15
CA2155322A1 (en) 1994-09-15
JP3852946B2 (ja) 2006-12-06
NO953564L (no) 1995-11-07
PL310556A1 (en) 1995-12-27
NO313199B1 (no) 2002-08-26
AU694419B2 (en) 1998-07-23
FI954250A0 (fi) 1995-09-11
BR1101034A (pt) 2002-04-30
FI954250L (fi) 1995-09-11
IL108910A0 (en) 1994-06-24
CZ9502290A3 (cs) 2001-08-15
EP0690864A1 (en) 1996-01-10
LU91206I2 (fr) 2006-05-30
PL184611B1 (pl) 2002-11-29
DK0690864T3 (da) 2001-09-17
DE69427469D1 (en) 2001-07-19
DE69427469T2 (de) 2001-10-31
KR100296810B1 (ko) 2001-10-24
TW267170B (cs) 1996-01-01
NO953564D0 (no) 1995-09-11
NZ263002A (en) 1996-12-20
NL300208I2 (nl) 2006-05-01
FR05C0045I1 (cs) 2006-01-06
IL108910A (en) 1999-10-28
HU9501960D0 (en) 1995-09-28
RU2136685C1 (ru) 1999-09-10
HUT73781A (en) 1996-09-30
CZ289332B6 (cs) 2002-01-16
LV12889B (lv) 2002-12-20
EP0690864B1 (en) 2001-06-13
FI120307B (fi) 2009-09-15
ES2157254T3 (es) 2001-08-16
HU222244B1 (hu) 2003-05-28
CN1055090C (zh) 2000-08-02

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