SG58382G - Cephalosporin antibiotics - Google Patents
Cephalosporin antibioticsInfo
- Publication number
- SG58382G SG58382G SG583/82A SG58382A SG58382G SG 58382 G SG58382 G SG 58382G SG 583/82 A SG583/82 A SG 583/82A SG 58382 A SG58382 A SG 58382A SG 58382 G SG58382 G SG 58382G
- Authority
- SG
- Singapore
- Prior art keywords
- cephalosporin antibiotics
- cephalosporin
- antibiotics
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/587—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with aliphatic hydrocarbon radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms, said aliphatic radicals being substituted in the alpha-position to the ring by a hetero atom, e.g. with m >= 0, Z being a singly or a doubly bound hetero atom
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Cephalosporin Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB2291378 | 1978-05-26 | ||
GB2291178 | 1978-05-26 |
Publications (1)
Publication Number | Publication Date |
---|---|
SG58382G true SG58382G (en) | 1983-09-02 |
Family
ID=26256190
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SG583/82A SG58382G (en) | 1978-05-26 | 1982-11-16 | Cephalosporin antibiotics |
Country Status (27)
Country | Link |
---|---|
US (2) | US4258041A (fr) |
AR (2) | AR228726A1 (fr) |
AT (1) | AT370420B (fr) |
AU (1) | AU524671B2 (fr) |
CA (1) | CA1127633A (fr) |
CH (2) | CH646178A5 (fr) |
DE (1) | DE2921316C2 (fr) |
DK (1) | DK157685C (fr) |
ES (2) | ES480914A1 (fr) |
FI (2) | FI67555C (fr) |
FR (2) | FR2426695A1 (fr) |
HK (1) | HK40183A (fr) |
IE (2) | IE49173B1 (fr) |
IL (3) | IL57400A (fr) |
IT (1) | IT1116198B (fr) |
KE (1) | KE3252A (fr) |
LU (1) | LU81319A1 (fr) |
MY (1) | MY8400017A (fr) |
NL (2) | NL176855C (fr) |
NO (2) | NO155347C (fr) |
NZ (2) | NZ190558A (fr) |
PH (1) | PH16961A (fr) |
PT (2) | PT69670A (fr) |
SE (2) | SE438507B (fr) |
SG (1) | SG58382G (fr) |
SI (2) | SI7911231A8 (fr) |
YU (2) | YU41635B (fr) |
Families Citing this family (112)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4963542A (en) * | 1976-09-08 | 1990-10-16 | Takeda Chemical Industries, Ltd. | Cephalosporin derivatives |
DE2714880A1 (de) * | 1977-04-02 | 1978-10-26 | Hoechst Ag | Cephemderivate und verfahren zu ihrer herstellung |
AR228726A1 (es) * | 1978-05-26 | 1983-04-15 | Glaxo Group Ltd | Procedimiento para la preparacion del antibiotico(6r,7r)-7-((z)-2-(2-aminotiazol-4-il)-2-(2-carboxiprop-2-oxiimino)acetamido)-3-(1-piridiniometil)cef-3-em-4-carboxilato |
US4237128A (en) * | 1979-04-12 | 1980-12-02 | E. R. Squibb & Sons, Inc. | 7-[2-(2-Amino-4-thiazolyl)-2-[(1-carboxy-1,1-dialkyl)alkoxyimino]acetamido]cephem sulfoxides |
GB2052490B (en) * | 1979-05-25 | 1983-09-07 | Glaxo Group Ltd | Intermediates for use in the preparation of cephalosporin antibiotics |
US4329453A (en) * | 1979-10-02 | 1982-05-11 | Glaxo Group Limited | Cephalosporin antibiotic |
BE885487A (fr) * | 1979-10-02 | 1981-04-01 | Glaxo Group Ltd | Nouvelles cephalosporines et leur preparation |
JPS5657789A (en) * | 1979-10-02 | 1981-05-20 | Glaxo Group Ltd | Novel cephalosporin antibiotic |
US4338313A (en) * | 1979-10-12 | 1982-07-06 | Fujisawa Pharmaceutical Co., Ltd. | Cephem compounds |
US4332800A (en) * | 1979-10-12 | 1982-06-01 | Fujisawa Pharmaceutical Co., Ltd. | Cephem compounds |
DE3006888A1 (de) * | 1980-02-23 | 1981-09-10 | Hoechst Ag, 6000 Frankfurt | Cephalosporinderivate und verfahren zu ihrer herstellung |
FR2476647A2 (fr) * | 1980-02-26 | 1981-08-28 | Roussel Uclaf | Procede de preparation de derives de l'acide 2-(2-amino protege 4-thiazolyl) 2-alkoxyimino acetique isomere syn |
US4252802A (en) * | 1980-03-13 | 1981-02-24 | E. R. Squibb & Sons, Inc. | Hydroxamic acid derivatives of 7-[(2-amino-4-thiazolyl)-oximino] cephalosporins |
GR75706B (fr) * | 1980-06-30 | 1984-08-02 | Sanofi Sa | |
US4443444A (en) * | 1980-08-11 | 1984-04-17 | Fujisawa Pharmaceutical Co., Ltd. | Cephem compounds |
DE3175156D1 (en) * | 1980-08-29 | 1986-09-25 | Fujisawa Pharmaceutical Co | New cephem compounds and processes for preparation thereof |
NZ198350A (en) * | 1980-09-25 | 1985-02-28 | Toyama Chemical Co Ltd | Cephalosporins and intermediates;pharmaceutical compositions |
FR2494276A2 (fr) * | 1980-11-20 | 1982-05-21 | Rhone Poulenc Ind | Nouvelles vinyl-3 cephalosporines, et leur preparation |
US4427677A (en) | 1980-12-31 | 1984-01-24 | Fujisawa Pharmaceutical Co., Ltd. | Cephem compounds |
JPS57144291A (en) * | 1981-03-02 | 1982-09-06 | Ajinomoto Co Inc | Preparation of imidazoledicarboxylic acid derivative |
US4336253A (en) * | 1981-03-11 | 1982-06-22 | Eli Lilly And Company | Cephalosporin antibiotics |
JPS6011917B2 (ja) * | 1981-04-09 | 1985-03-28 | 山之内製薬株式会社 | 新規なセファロスポリン化合物 |
DE3118732A1 (de) * | 1981-05-12 | 1982-12-02 | Hoechst Ag, 6000 Frankfurt | Cephalosporinderivate und verfahren zu ihrer herstellung |
GR75487B (fr) * | 1981-06-22 | 1984-07-23 | Fujisawa Pharmaceutical Co | |
US4436912A (en) | 1981-09-08 | 1984-03-13 | Eli Lilly And Company | 7-[2-(2-Aminooxazol-4-yl)-2-(oximino)acetamido cephalosporin antibiotics and intermediates therefor |
US4382931A (en) * | 1981-09-08 | 1983-05-10 | Eli Lilly And Company | 3'-Substituted quinolinium cephalosporins |
US4382932A (en) * | 1981-09-08 | 1983-05-10 | Eli Lilly And Company | Isoquinolinium substituted cephalosporins |
US4577014A (en) * | 1981-09-08 | 1986-03-18 | Eli Lilly And Company | Thieno and furopyridinium-substituted cephalosporins |
US4406898A (en) * | 1981-09-08 | 1983-09-27 | Eli Lilly And Company | Oxazole and oxadiazole cephalosporins |
US4430499A (en) | 1981-09-08 | 1984-02-07 | Eli Lilly And Company | 7-[2-(2-Aminooxazol-4-yl)-2-(oximino)acetamido]cephalosporin antibiotics |
JPS5859991A (ja) * | 1981-09-14 | 1983-04-09 | Fujisawa Pharmaceut Co Ltd | 新規セフェム化合物 |
US4401668A (en) * | 1981-10-02 | 1983-08-30 | Eli Lilly And Company | Pyrazinium substituted cephalosporins |
US4450270A (en) * | 1981-10-02 | 1984-05-22 | Eli Lilly And Company | Dioximino cephalosporin antibiotics |
US4379787A (en) * | 1981-10-02 | 1983-04-12 | Eli Lilly And Company | Oximino-substituted cephalosporin compounds |
US4388316A (en) * | 1981-10-02 | 1983-06-14 | Eli Lilly And Company | Amino-substituted oxazole, oxadiazole and isoxazole-substituted cephalosporins |
US4402955A (en) * | 1981-10-02 | 1983-09-06 | Eli Lilly And Company | Dioximino cephalosporin antibiotics |
US4406887A (en) * | 1981-10-13 | 1983-09-27 | Bristol-Myers Company | Method for treating resistant bacteria including anaerobes |
ATE18219T1 (de) * | 1981-11-13 | 1986-03-15 | Glaxo Group Ltd | Thiazol-derivate und ihre verwendung bei der herstellung von beta-lactam-antibiotika. |
EP0088183B1 (fr) * | 1981-11-13 | 1985-08-07 | Glaxo Group Limited | Dérivés de thiazole et leur utilisation dans la préparation d'antibiotiques bêta lactame |
US4474954A (en) * | 1981-12-07 | 1984-10-02 | Bristol-Myers Company | Intermediates for cephalosporin derivatives |
US4394503A (en) * | 1981-12-07 | 1983-07-19 | Bristol-Myers Company | Cephalosporin derivatives |
US4501739A (en) * | 1982-01-19 | 1985-02-26 | Eli Lilly And Company | Thieno and furopyridinium-substituted cephalosporins |
DE3207840A1 (de) * | 1982-03-04 | 1983-09-15 | Hoechst Ag, 6230 Frankfurt | "cephalosporinderivate und verfahren zu ihrer herstellung" |
CA1213882A (fr) * | 1982-03-04 | 1986-11-12 | Jun Okumura | Cephalosporines |
US4552696A (en) * | 1982-04-09 | 1985-11-12 | Bristol-Myers Company | Carbapenem antibiotics |
JPS58194871A (ja) * | 1982-04-29 | 1983-11-12 | グラクソ・グル−プ・リミテツド | 抗生物質の製造における改良 |
JPS5910593A (ja) | 1982-06-28 | 1984-01-20 | Bristol Mayers Kenkyusho Kk | セフアロスポリン誘導体 |
IE55406B1 (en) * | 1982-08-07 | 1990-09-12 | Tanabe Seiyaku Co | Novel cephalosporin compounds and preparation thereof |
ES525492A0 (es) * | 1982-09-10 | 1985-02-01 | Glaxo Group Ltd | Un procedimiento para la produccion de un recipiente hermeticamente cerrado que contiene al menos un antibiotico de beta-lactama. |
DE3381408D1 (de) * | 1982-12-27 | 1990-05-10 | Lilly Co Eli | Zwischenverbindungen fuer die herstellung von ceftazidin und verfahren zu ihrer herstellung. |
EP0115770B2 (fr) * | 1983-01-07 | 1996-06-19 | Takeda Chemical Industries, Ltd. | Dérivés de thiazoles |
US4486586A (en) * | 1983-02-10 | 1984-12-04 | Bristol-Myers Company | Cephalosporin derivatives |
DE3313818A1 (de) * | 1983-04-16 | 1984-10-18 | Hoechst Ag, 6230 Frankfurt | Neue kristallmodifikation von ceftazidim |
DE3313816A1 (de) * | 1983-04-16 | 1984-10-18 | Hoechst Ag, 6230 Frankfurt | Neue kristallmodifikation von ceftazidim |
DE3316797A1 (de) * | 1983-05-07 | 1984-11-08 | Hoechst Ag, 6230 Frankfurt | Verfahren zur herstellung von cephemverbindungen |
DE3316798A1 (de) * | 1983-05-07 | 1984-11-08 | Hoechst Ag, 6230 Frankfurt | Verfahren zur herstellung von cephemverbindungen |
US4540779A (en) * | 1983-06-20 | 1985-09-10 | Eli Lilly And Company | Crystalline 7-(R)-amino-3-(1'pyridiniummethyl)-ceph-3-em-4-carboxylate monohydrochloride monohydrate compound |
US4497811A (en) * | 1983-07-01 | 1985-02-05 | Seiji Shibahara | 1-Oxadethiacephalosporin compound and antibacterial agent containing the _same |
JPS6061528A (ja) * | 1983-09-09 | 1985-04-09 | ブリストル―マイヤーズ スクイブ カンパニー | 嫌気性菌を包含する耐性バクテリアの処理法 |
AU566944B2 (en) * | 1983-10-07 | 1987-11-05 | Gist-Brocades N.V. | Preparation of 3-cephem derivatives |
JPS60178891A (ja) * | 1984-02-24 | 1985-09-12 | Kureha Chem Ind Co Ltd | セファロスポリン誘導体及び該誘導体を含有する医薬 |
GB8406218D0 (en) * | 1984-03-09 | 1984-04-11 | Glaxo Group Ltd | Process |
US4537959A (en) * | 1984-03-26 | 1985-08-27 | Eli Lilly And Company | Crystalline cephalosporin antibiotic salt |
US4788185A (en) * | 1984-04-23 | 1988-11-29 | Takeda Chemical Industries, Ltd. | Cephalosporin compounds |
PH22107A (en) * | 1984-06-07 | 1988-06-01 | Takeda Chemical Industries Ltd | 3-pyrazolo(1,5-a)pyrdinium cephem compounds |
CA1236089A (fr) * | 1984-06-25 | 1988-05-03 | Perry C. Heath | Ceftazidime |
US4616080A (en) * | 1984-07-02 | 1986-10-07 | Eli Lilly And Company | Simplified process of forming crystalline ceftazidime pentahydrate |
US4626534A (en) * | 1984-07-23 | 1986-12-02 | Eli Lilly And Company | Pharmaceutical formulation |
EP0175544A3 (fr) * | 1984-09-17 | 1987-06-03 | Eli Lilly And Company | Procédé pour la préparation d'intermédiaires de céphalosporine |
US4659813A (en) * | 1984-11-08 | 1987-04-21 | Eli Lilly And Company | Crystallization process for ceftazidime derivative |
WO1988010263A1 (fr) * | 1987-06-25 | 1988-12-29 | Banyu Pharmaceutical Co., Ltd. | Composes cristallins de cephalosporine, procede de preparation et produits intermediaires pour la preparation de ces composes |
GB8504072D0 (en) * | 1985-02-18 | 1985-03-20 | Fujisawa Pharmaceutical Co | Cephem compounds |
ATE89826T1 (de) * | 1985-03-01 | 1993-06-15 | Takeda Chemical Industries Ltd | Antibakterielle verbindungen, ihre herstellung und verwendung. |
US4703118A (en) * | 1985-04-08 | 1987-10-27 | Eli Lilly And Company | Synthesis of 3-iodomethyl cephalosporins |
US4692518A (en) * | 1985-11-06 | 1987-09-08 | Eli Lilly And Company | Crystalline (7R)-7-amino-3-(1'-pyridiniummethyl)-3-cephem-4-carboxylate monohydrate compound |
JPS62175489A (ja) * | 1986-01-29 | 1987-08-01 | Sanwa Kagaku Kenkyusho:Kk | 新規なセフアロスポリン誘導体及びその塩、これらの製法並びに該化合物を有効成分とする感染症治療剤 |
US5359057A (en) * | 1986-02-07 | 1994-10-25 | Hoffmann-La Roche Inc. | Acylation of amines |
JPS63107989A (ja) * | 1986-06-04 | 1988-05-12 | Tanabe Seiyaku Co Ltd | セファロスポリン化合物 |
AT387022B (de) * | 1986-06-04 | 1988-11-25 | Biochemie Gmbh | Verfahren zur herstellung einer neuen kristallinen form eines cefalosporinderivats |
IL82738A0 (en) * | 1986-06-16 | 1987-12-20 | Tanabe Seiyaku Co | Cephalosporin compounds,their preparation and pharmaceutical compositions containing them |
WO1988002001A1 (fr) * | 1986-09-10 | 1988-03-24 | Biochemie Gesellschaft M.B.H. | Nouvelle forme cristalline stable d'un produit intermediaire de la cephalosporine |
US4954624A (en) * | 1986-10-07 | 1990-09-04 | Sandoz Ltd. | Process for the production of cephalosporin derivatives |
ES2032543T3 (es) * | 1987-02-02 | 1993-02-16 | Eli Lilly And Company | Procedimiento mejorado de preparacion de un antibiotico. |
US5021564A (en) * | 1987-02-02 | 1991-06-04 | Eli Lilly And Company | Process for preparing ceftazidime pentahydrate |
GB8802622D0 (en) * | 1988-02-05 | 1988-03-02 | Glaxo Group Ltd | Chemical compound |
KR0159760B1 (ko) * | 1988-12-27 | 1998-12-01 | 리로이 휘테커 | 아실화 방법 |
US5194604A (en) * | 1990-06-29 | 1993-03-16 | E. R. Squibb & Sons, Inc. | Process and intermediates for beta-lactams having aminothiazole(iminooxyacetic acid)acetic acid sidechains |
KR940000112B1 (ko) * | 1990-07-05 | 1994-01-05 | 주식회사 대웅제약 | 신규의 3-치환 세펨화합물 및 그의 제조방법 |
US5281589A (en) * | 1991-06-15 | 1994-01-25 | Cheil Foods & Chemicals, Inc. | 3-fused pyridiniummethyl cephalosporins |
KR100194994B1 (ko) * | 1993-06-05 | 1999-06-15 | 손경식 | 새로운 세펨 화합물 |
AU690685B2 (en) * | 1994-04-25 | 1998-04-30 | Smithkline Beecham Plc | Pharmaceutical formulations containing a beta-lactamase inhibiting penem in combination with a beta-lactam antibiotic and their use in the treatment of bacterial infections |
US6472383B1 (en) | 1994-04-25 | 2002-10-29 | Smithkline Beecham P.L.C. | Pharmaceutical formulations |
CN1150429A (zh) * | 1994-05-23 | 1997-05-21 | 韩国科学技术研究院 | 头孢菌素化合物及其制备方法 |
US5831085A (en) * | 1997-01-16 | 1998-11-03 | Lupin Laboratories Limited | Process for manufacture of cephalosporin such as ceftazidime and intermediate thereof |
IN189047B (fr) | 1998-06-01 | 2002-12-14 | Ranbaxy Lab Ltd | |
US6930983B2 (en) * | 2000-03-15 | 2005-08-16 | Texas Instruments Incorporated | Integrated circuits, systems, apparatus, packets and processes utilizing path diversity for media over packet applications |
KR100342600B1 (ko) | 2000-03-06 | 2002-07-04 | 한미정밀화학주식회사 | 신규한 티아졸 화합물 및 그의 제조 방법 |
KR100392409B1 (ko) | 2000-03-20 | 2003-07-22 | 한미정밀화학주식회사 | 신규한 티아졸 화합물을 이용한 세팔로스포린계항생물질의 제조 방법 |
US6911441B2 (en) * | 2002-12-16 | 2005-06-28 | Akzo Nobel N.V. | Prolonged release pharmaceutical composition |
CN1312158C (zh) * | 2005-05-20 | 2007-04-25 | 天津市医药集团技术发展有限公司 | 一种头孢克肟的制备方法 |
EP2209474A4 (fr) | 2007-10-09 | 2013-07-24 | Sopharmia Inc | Inhibiteurs de bêta-lactamase à large spectre |
CN101293891B (zh) * | 2008-06-12 | 2011-01-12 | 齐鲁安替制药有限公司 | 头孢他啶中间体的制备方法 |
EP2862569A1 (fr) | 2011-09-09 | 2015-04-22 | Cubist Pharmaceuticals, Inc. | Procédés pour traiter des infections intrapulmonaires |
US8809314B1 (en) | 2012-09-07 | 2014-08-19 | Cubist Pharmacueticals, Inc. | Cephalosporin compound |
US8476425B1 (en) | 2012-09-27 | 2013-07-02 | Cubist Pharmaceuticals, Inc. | Tazobactam arginine compositions |
MD4599C1 (ro) | 2013-03-13 | 2019-06-30 | Theravance Biopharma Antibiotics Ip, Llc | Săruri de hidroclorură a unui compus antibiotic |
US9320740B2 (en) | 2013-03-15 | 2016-04-26 | Merck Sharp & Dohme Corp. | Ceftolozane-tazobactam pharmaceutical compositions |
KR102226197B1 (ko) | 2013-03-15 | 2021-03-11 | 머크 샤프 앤드 돔 코포레이션 | 세프톨로잔 항균성 조성물 |
US9872906B2 (en) | 2013-03-15 | 2018-01-23 | Merck Sharp & Dohme Corp. | Ceftolozane antibiotic compositions |
WO2015035376A2 (fr) | 2013-09-09 | 2015-03-12 | Calixa Therapeutics, Inc. | Traitement d'infections au moyen de ceftolozane/tazobactam chez des sujets ayant une fonction rénale altérée |
US20150094293A1 (en) | 2013-09-27 | 2015-04-02 | Calixa Therapeutics, Inc. | Solid forms of ceftolozane |
CN106336418B (zh) * | 2016-08-19 | 2019-02-01 | 上海上药新亚药业有限公司 | 一种头孢他啶盐酸盐的固相合成法 |
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US4079178A (en) * | 1971-05-14 | 1978-03-14 | Glaxo Laboratories Limited | Cephalosporins having (α-etherified oximino) acylamido groups at the 7-position |
US3971778A (en) * | 1972-05-12 | 1976-07-27 | Glaxo Laboratories Limited | Cephalosporins having (α-etherified oximino)acylamido groups at the 7-position |
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US4017515A (en) * | 1971-05-14 | 1977-04-12 | Glaxo Laboratories Limited | α-(Etherified oximino) carboxylic acids and acid chlorides |
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GB1399086A (en) | 1971-05-14 | 1975-06-25 | Glaxo Lab Ltd | Cephalosporin compounds |
US4024133A (en) * | 1971-05-14 | 1977-05-17 | Glaxo Laboratories Limited | 7β-[2-Etherified oximino-2-(thienyl-,furyl- or pyridylacetamido)]cephalosporins |
US4024137A (en) * | 1971-05-14 | 1977-05-17 | Glaxo Laboratories Limited | 7β-[2-Etherified oximino-2-(phenyl- or naphthylacetamido)] cephalosporins |
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US4144393A (en) * | 1973-12-21 | 1979-03-13 | Glaxo Laboratories Limited | 3-Acetoxymethyl cephalosporins having at position-7 a carboxy substituted α-etherified hydroxyiminoarylacetamido group |
GB1496757A (en) | 1973-12-21 | 1978-01-05 | Glaxo Lab Ltd | Cephalosporin derivatives |
US4144392A (en) * | 1973-12-21 | 1979-03-13 | Glaxo Laboratories Limited | Cephalosporins having at position-7 a carboxy substituted α-etherified hydroxyimino-arylacetamido group and at position-3 the residue of a sulphur nucleophile |
US4060686A (en) * | 1973-12-21 | 1977-11-29 | Janice Bradshaw | Cephalosporins having a 7-(carboxy substituted α-etherified oximinoarylacetamido) group |
US4162360A (en) * | 1973-12-21 | 1979-07-24 | Glaxo Laboratories Limited | 3-Carbamoyloxymethyl-7-substituted oximino acetamido cephalosporanic acid derivatives |
US4032950A (en) * | 1974-12-06 | 1977-06-28 | Hughes Aircraft Company | Liquid phase epitaxial process for growing semi-insulating gaas layers |
DK154939C (da) * | 1974-12-19 | 1989-06-12 | Takeda Chemical Industries Ltd | Analogifremgangsmaade til fremstilling af thiazolylacetamido-cephemforbindelser eller farmaceutisk acceptable salte eller estere deraf |
DE2760123C2 (de) * | 1976-01-23 | 1986-04-30 | Roussel-Uclaf, Paris | 7-Aminothiazolyl-syn-oxyiminoacetamidocephalosporansäuren, ihre Herstellung und sie enthaltende pharmazeutische Zusammensetzungen |
US4165430A (en) * | 1976-03-19 | 1979-08-21 | Glaxo Laboratories Limited | Cephalosporins having a 7-carboxy substituted α-etherified oximinoarylacetamido) group |
US4166115A (en) * | 1976-04-12 | 1979-08-28 | Fujisawa Pharmaceutical Co., Ltd. | Syn 7-oxoimino substituted derivatives of cephalosporanic acid |
JPS52125188A (en) | 1976-04-14 | 1977-10-20 | Takeda Chem Ind Ltd | Cephalosporin derivatives and their preparation |
ZA781502B (en) | 1977-03-14 | 1979-09-26 | Fujisawa Pharmaceutical Co | New cephem and cepham compounds and processes for preparation thereof |
FR2384782A1 (fr) | 1977-03-25 | 1978-10-20 | Roussel Uclaf | Nouvelles oximes derivees de l'acide 3-acetoxymethyl 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments |
DE2714880A1 (de) * | 1977-04-02 | 1978-10-26 | Hoechst Ag | Cephemderivate und verfahren zu ihrer herstellung |
ZA781870B (en) | 1977-04-02 | 1979-03-28 | Hoechst Ag | Cephem derivatives and process for their manufacture |
DE2716677C2 (de) | 1977-04-15 | 1985-10-10 | Hoechst Ag, 6230 Frankfurt | Cephemderivate und Verfahren zu ihrer Herstellung |
GB1602725A (en) | 1977-04-27 | 1981-11-18 | Glaxo Operations Ltd | 7-(a-oxyiminoacetamido)-ceph-3-em-4-carboxylic acid derivatives |
AR228726A1 (es) * | 1978-05-26 | 1983-04-15 | Glaxo Group Ltd | Procedimiento para la preparacion del antibiotico(6r,7r)-7-((z)-2-(2-aminotiazol-4-il)-2-(2-carboxiprop-2-oxiimino)acetamido)-3-(1-piridiniometil)cef-3-em-4-carboxilato |
US4237128A (en) * | 1979-04-12 | 1980-12-02 | E. R. Squibb & Sons, Inc. | 7-[2-(2-Amino-4-thiazolyl)-2-[(1-carboxy-1,1-dialkyl)alkoxyimino]acetamido]cephem sulfoxides |
US4394503A (en) * | 1981-12-07 | 1983-07-19 | Bristol-Myers Company | Cephalosporin derivatives |
-
1979
- 1979-05-24 AR AR276665A patent/AR228726A1/es active
- 1979-05-24 AR AR276664A patent/AR229883A1/es active
- 1979-05-25 DK DK216779A patent/DK157685C/da active
- 1979-05-25 FI FI791678A patent/FI67555C/fi not_active IP Right Cessation
- 1979-05-25 AU AU47422/79A patent/AU524671B2/en not_active Expired
- 1979-05-25 CH CH491579A patent/CH646178A5/de not_active IP Right Cessation
- 1979-05-25 ES ES480914A patent/ES480914A1/es not_active Expired
- 1979-05-25 NZ NZ190558A patent/NZ190558A/xx unknown
- 1979-05-25 SE SE7904576A patent/SE438507B/sv not_active IP Right Cessation
- 1979-05-25 DE DE2921316A patent/DE2921316C2/de not_active Expired
- 1979-05-25 NO NO791731A patent/NO155347C/no unknown
- 1979-05-25 PT PT69670A patent/PT69670A/pt unknown
- 1979-05-25 IL IL57400A patent/IL57400A/xx unknown
- 1979-05-25 NL NLAANVRAGE7904122,A patent/NL176855C/xx not_active IP Right Cessation
- 1979-05-25 PT PT69669A patent/PT69669A/pt unknown
- 1979-05-25 IT IT7949179A patent/IT1116198B/it active Protection Beyond IP Right Term
- 1979-05-25 US US06/042,594 patent/US4258041A/en not_active Expired - Lifetime
- 1979-05-25 SI SI7911231A patent/SI7911231A8/sl unknown
- 1979-05-25 LU LU81319A patent/LU81319A1/fr unknown
- 1979-05-25 CA CA328,413A patent/CA1127633A/fr not_active Expired
- 1979-05-25 PH PH22562A patent/PH16961A/en unknown
- 1979-05-25 ES ES480915A patent/ES480915A1/es not_active Expired
- 1979-05-25 IL IL59793A patent/IL59793A/xx unknown
- 1979-05-25 CH CH1707/80A patent/CH649556A5/de not_active IP Right Cessation
- 1979-05-25 YU YU1231/79A patent/YU41635B/xx unknown
- 1979-05-28 FR FR7913531A patent/FR2426695A1/fr active Granted
- 1979-08-08 IE IE2453/80A patent/IE49173B1/en unknown
- 1979-08-08 IE IE1025/79A patent/IE49172B1/en not_active IP Right Cessation
-
1980
- 1980-03-06 NL NL8001348A patent/NL8001348A/nl not_active Application Discontinuation
- 1980-04-01 NZ NZ193326A patent/NZ193326A/xx unknown
- 1980-04-09 IL IL59793A patent/IL59793A0/xx unknown
- 1980-04-09 FR FR8007929A patent/FR2445835A1/fr active Granted
- 1980-05-19 FI FI801609A patent/FI67705C/fi not_active IP Right Cessation
-
1981
- 1981-05-27 AT AT0239281A patent/AT370420B/de not_active IP Right Cessation
-
1982
- 1982-09-13 US US06/417,656 patent/US4600772A/en not_active Expired - Lifetime
- 1982-10-05 YU YU2234/82A patent/YU43097B/xx unknown
- 1982-10-05 SI SI8212234A patent/SI8212234A8/sl unknown
- 1982-11-16 SG SG583/82A patent/SG58382G/en unknown
- 1982-11-26 KE KE3252A patent/KE3252A/xx unknown
-
1983
- 1983-10-13 HK HK401/83A patent/HK40183A/xx not_active IP Right Cessation
-
1984
- 1984-05-28 SE SE8402887A patent/SE8402887D0/xx not_active Application Discontinuation
- 1984-12-30 MY MY17/84A patent/MY8400017A/xx unknown
-
1985
- 1985-01-14 NO NO850153A patent/NO850153L/no unknown
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