SG11201810655QA - Method for producing substituted polycyclic pyridone derivative and crystal of same - Google Patents
Method for producing substituted polycyclic pyridone derivative and crystal of sameInfo
- Publication number
- SG11201810655QA SG11201810655QA SG11201810655QA SG11201810655QA SG11201810655QA SG 11201810655Q A SG11201810655Q A SG 11201810655QA SG 11201810655Q A SG11201810655Q A SG 11201810655QA SG 11201810655Q A SG11201810655Q A SG 11201810655QA SG 11201810655Q A SG11201810655Q A SG 11201810655QA
- Authority
- SG
- Singapore
- Prior art keywords
- crystal
- same
- substituted polycyclic
- pyridone derivative
- producing substituted
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 239000013078 crystal Chemical class 0.000 title 1
- -1 polycyclic pyridone derivative Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 3
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 159000000003 magnesium salts Chemical class 0.000 abstract 1
- 125000006239 protecting group Chemical group 0.000 abstract 1
- 159000000000 sodium salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D498/14—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5383—1,4-Oxazines, e.g. morpholine ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B2200/00—Indexing scheme relating to specific properties of organic compounds
- C07B2200/13—Crystalline forms, e.g. polymorphs
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B61/00—Other general methods
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Virology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Oncology (AREA)
- Molecular Biology (AREA)
- Communicable Diseases (AREA)
- Pulmonology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Pyridine Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2016121453 | 2016-06-20 | ||
| PCT/JP2017/022478 WO2017221869A1 (ja) | 2016-06-20 | 2017-06-19 | 置換された多環性ピリドン誘導体の製造方法およびその結晶 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SG11201810655QA true SG11201810655QA (en) | 2019-01-30 |
Family
ID=60783429
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SG11201810655QA SG11201810655QA (en) | 2016-06-20 | 2017-06-19 | Method for producing substituted polycyclic pyridone derivative and crystal of same |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US11261198B2 (ko) |
| EP (2) | EP4194459A1 (ko) |
| JP (2) | JP6212678B1 (ko) |
| KR (2) | KR102447711B1 (ko) |
| CN (2) | CN109311911B (ko) |
| AR (1) | AR108812A1 (ko) |
| AU (1) | AU2017282305B2 (ko) |
| BR (1) | BR112018076600A2 (ko) |
| CA (1) | CA3027840A1 (ko) |
| HR (1) | HRP20221540T1 (ko) |
| IL (1) | IL263812B2 (ko) |
| MX (1) | MX2018016267A (ko) |
| SG (1) | SG11201810655QA (ko) |
| TW (1) | TWI750188B (ko) |
| WO (1) | WO2017221869A1 (ko) |
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| CN110494141A (zh) | 2016-08-10 | 2019-11-22 | 盐野义制药株式会社 | 含有被取代的多环性吡啶酮衍生物及其前药的药物组合物 |
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| EP3693373A4 (en) | 2017-10-06 | 2021-11-03 | Shionogi & Co., Ltd. | PROCESS FOR THE STEREOSELECTIVE PRODUCTION OF SUBSTITUTED POLYCYCLIC PYRIDONE DERIVATIVES |
| CN110357850A (zh) * | 2018-03-26 | 2019-10-22 | 广东东阳光药业有限公司 | 一种含硫杂环化合物的制备方法 |
| BR112020021059B1 (pt) | 2018-04-24 | 2022-08-30 | Shionogi & Co., Ltd | Forma de dosagem sólida |
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| WO2020181025A1 (en) | 2019-03-05 | 2020-09-10 | Assia Chemical Industries Ltd | Solid state forms of baloxavir marboxil |
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| CN115135646B (zh) * | 2019-12-23 | 2024-05-17 | 石家庄迪斯凯威医药科技有限公司 | 取代的多环化合物及其药物组合物和用途 |
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2017
- 2017-06-19 TW TW106120359A patent/TWI750188B/zh active
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- 2017-06-19 JP JP2017538748A patent/JP6212678B1/ja active Active
- 2017-06-19 KR KR1020197001315A patent/KR102447711B1/ko active IP Right Grant
- 2017-06-19 AU AU2017282305A patent/AU2017282305B2/en active Active
- 2017-06-19 WO PCT/JP2017/022478 patent/WO2017221869A1/ja unknown
- 2017-06-19 AR ARP170101679A patent/AR108812A1/es unknown
- 2017-06-19 IL IL263812A patent/IL263812B2/en unknown
- 2017-06-19 SG SG11201810655QA patent/SG11201810655QA/en unknown
- 2017-06-19 EP EP22206730.8A patent/EP4194459A1/en not_active Withdrawn
- 2017-06-19 CN CN202110909230.XA patent/CN113717198A/zh active Pending
- 2017-06-19 MX MX2018016267A patent/MX2018016267A/es unknown
- 2017-06-19 HR HRP20221540TT patent/HRP20221540T1/hr unknown
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- 2017-06-19 BR BR112018076600-3A patent/BR112018076600A2/pt unknown
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- 2017-09-05 JP JP2017170491A patent/JP6959077B2/ja active Active
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2022
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Also Published As
| Publication number | Publication date |
|---|---|
| IL263812B2 (en) | 2023-09-01 |
| EP3473629A4 (en) | 2020-01-22 |
| EP4194459A1 (en) | 2023-06-14 |
| US11261198B2 (en) | 2022-03-01 |
| JP6212678B1 (ja) | 2017-10-11 |
| AU2017282305A1 (en) | 2018-12-06 |
| EP3473629B1 (en) | 2022-11-16 |
| CA3027840A1 (en) | 2017-12-28 |
| TW201802097A (zh) | 2018-01-16 |
| MX2018016267A (es) | 2019-05-20 |
| EP3473629A1 (en) | 2019-04-24 |
| KR20220084425A (ko) | 2022-06-21 |
| AU2017282305B2 (en) | 2021-06-10 |
| KR102447711B1 (ko) | 2022-09-28 |
| AR108812A1 (es) | 2018-09-26 |
| JP6959077B2 (ja) | 2021-11-02 |
| CN109311911A (zh) | 2019-02-05 |
| KR102586854B1 (ko) | 2023-10-11 |
| JP2018024682A (ja) | 2018-02-15 |
| US20220251107A1 (en) | 2022-08-11 |
| TWI750188B (zh) | 2021-12-21 |
| CN109311911B (zh) | 2021-11-16 |
| US20210230187A1 (en) | 2021-07-29 |
| JPWO2017221869A1 (ja) | 2018-07-05 |
| CN113717198A (zh) | 2021-11-30 |
| WO2017221869A1 (ja) | 2017-12-28 |
| IL263812B1 (en) | 2023-05-01 |
| US11807648B2 (en) | 2023-11-07 |
| KR20190017991A (ko) | 2019-02-20 |
| BR112018076600A2 (pt) | 2019-04-16 |
| HRP20221540T1 (hr) | 2023-03-03 |
| IL263812A (en) | 2019-01-31 |
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