MX2018016267A - Metodo para producir derivado de piridona policiclica sustituida y cristal del mismo. - Google Patents

Metodo para producir derivado de piridona policiclica sustituida y cristal del mismo.

Info

Publication number
MX2018016267A
MX2018016267A MX2018016267A MX2018016267A MX2018016267A MX 2018016267 A MX2018016267 A MX 2018016267A MX 2018016267 A MX2018016267 A MX 2018016267A MX 2018016267 A MX2018016267 A MX 2018016267A MX 2018016267 A MX2018016267 A MX 2018016267A
Authority
MX
Mexico
Prior art keywords
formula
crystal
same
substituted polycyclic
pyridone derivative
Prior art date
Application number
MX2018016267A
Other languages
English (en)
Inventor
Shibahara Setsuya
Fukui Nobuaki
Maki Toshikatsu
Anan Kosuke
Original Assignee
Shionogi & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=60783429&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=MX2018016267(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Shionogi & Co filed Critical Shionogi & Co
Publication of MX2018016267A publication Critical patent/MX2018016267A/es

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D498/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5383—1,4-Oxazines, e.g. morpholine ortho- or peri-condensed with heterocyclic ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B61/00—Other general methods
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Oncology (AREA)
  • Molecular Biology (AREA)
  • Communicable Diseases (AREA)
  • Pulmonology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

Se proporciona un método para producir un derivado de piridona policíclico sustituido. Un método para producir un compuesto representado por la fórmula (II), que se caracteriza porque un compuesto representado por la fórmula (I) se hace reaccionar con un compuesto representado por la fórmula R2-OH (en donde R2 representa un grupo alquilo no sustituido) en LA presencia de Una sal de sodio y/o una sal de magnesio. (En la fórmula (I), R1 representa un átomo de hidrógeno o un grupo protector distinto de un grupo alquilo no sustituido). (En la fórmula (II), R2 es como se definió anteriormente).
MX2018016267A 2016-06-20 2017-06-19 Metodo para producir derivado de piridona policiclica sustituida y cristal del mismo. MX2018016267A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2016121453 2016-06-20
PCT/JP2017/022478 WO2017221869A1 (ja) 2016-06-20 2017-06-19 置換された多環性ピリドン誘導体の製造方法およびその結晶

Publications (1)

Publication Number Publication Date
MX2018016267A true MX2018016267A (es) 2019-05-20

Family

ID=60783429

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2018016267A MX2018016267A (es) 2016-06-20 2017-06-19 Metodo para producir derivado de piridona policiclica sustituida y cristal del mismo.

Country Status (15)

Country Link
US (2) US11261198B2 (es)
EP (2) EP4194459A1 (es)
JP (2) JP6212678B1 (es)
KR (2) KR102586854B1 (es)
CN (2) CN113717198A (es)
AR (1) AR108812A1 (es)
AU (1) AU2017282305B2 (es)
BR (1) BR112018076600A2 (es)
CA (1) CA3027840A1 (es)
HR (1) HRP20221540T1 (es)
IL (1) IL263812B2 (es)
MX (1) MX2018016267A (es)
SG (1) SG11201810655QA (es)
TW (1) TWI750188B (es)
WO (1) WO2017221869A1 (es)

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CN109311911A (zh) 2019-02-05
JPWO2017221869A1 (ja) 2018-07-05
CN113717198A (zh) 2021-11-30
US11261198B2 (en) 2022-03-01
CA3027840A1 (en) 2017-12-28
US20210230187A1 (en) 2021-07-29
IL263812B1 (en) 2023-05-01
KR102586854B1 (ko) 2023-10-11
JP6959077B2 (ja) 2021-11-02
KR102447711B1 (ko) 2022-09-28
TWI750188B (zh) 2021-12-21
EP3473629B1 (en) 2022-11-16
EP4194459A1 (en) 2023-06-14
IL263812A (en) 2019-01-31
EP3473629A1 (en) 2019-04-24
AU2017282305A1 (en) 2018-12-06
WO2017221869A1 (ja) 2017-12-28
CN109311911B (zh) 2021-11-16
TW201802097A (zh) 2018-01-16
KR20220084425A (ko) 2022-06-21
AU2017282305B2 (en) 2021-06-10
HRP20221540T1 (hr) 2023-03-03
JP6212678B1 (ja) 2017-10-11
EP3473629A4 (en) 2020-01-22
KR20190017991A (ko) 2019-02-20
IL263812B2 (en) 2023-09-01
US20220251107A1 (en) 2022-08-11
BR112018076600A2 (pt) 2019-04-16
US11807648B2 (en) 2023-11-07
AR108812A1 (es) 2018-09-26
JP2018024682A (ja) 2018-02-15
SG11201810655QA (en) 2019-01-30

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