MA39715A - Formes polymorphes de l'acide 4,5-dihydro-1h-pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylique et de son sel de disodium, procédé de préparation desdites formes polymorphes et leur utilisation - Google Patents

Formes polymorphes de l'acide 4,5-dihydro-1h-pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylique et de son sel de disodium, procédé de préparation desdites formes polymorphes et leur utilisation

Info

Publication number
MA39715A
MA39715A MA039715A MA39715A MA39715A MA 39715 A MA39715 A MA 39715A MA 039715 A MA039715 A MA 039715A MA 39715 A MA39715 A MA 39715A MA 39715 A MA39715 A MA 39715A
Authority
MA
Morocco
Prior art keywords
pyrrolo
quinoline
dihydro
preparation
disodium salt
Prior art date
Application number
MA039715A
Other languages
English (en)
Inventor
Rajulu Gavara Govinda
Ravindra Chandrappa Koramangala
Tom Thomas Puthiaparampil
Ganesh Sambasivam
Original Assignee
Anthem Biosciences Private Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Anthem Biosciences Private Ltd filed Critical Anthem Biosciences Private Ltd
Publication of MA39715A publication Critical patent/MA39715A/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/13—Crystalline forms, e.g. polymorphs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)

Abstract

La présente invention concerne une forme polymorphe de pqq et/ou de ses sels, représentée par la formule (i), dans laquelle "n" et "m" sont choisis dans le groupe constitué par : (a) "n" = 3, "m" = 0 et (b) "n" = 1, "m" = 2; et r3 est na+. Un procédé de préparation de la forme polymorphe du composé de formule (i) et/ou de ses sels, une composition les contenant et leur utilisation sont en outre décrits.
MA039715A 2014-04-16 2015-04-14 Formes polymorphes de l'acide 4,5-dihydro-1h-pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylique et de son sel de disodium, procédé de préparation desdites formes polymorphes et leur utilisation MA39715A (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IN1988CH2014 2014-04-16

Publications (1)

Publication Number Publication Date
MA39715A true MA39715A (fr) 2015-10-22

Family

ID=53059367

Family Applications (1)

Application Number Title Priority Date Filing Date
MA039715A MA39715A (fr) 2014-04-16 2015-04-14 Formes polymorphes de l'acide 4,5-dihydro-1h-pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylique et de son sel de disodium, procédé de préparation desdites formes polymorphes et leur utilisation

Country Status (6)

Country Link
US (1) US20170022200A1 (fr)
EP (1) EP3131899A1 (fr)
JP (1) JP2017513863A (fr)
CN (1) CN106255691A (fr)
MA (1) MA39715A (fr)
WO (1) WO2015159236A1 (fr)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10364244B2 (en) * 2015-09-25 2019-07-30 Zhejiang Hisun Pharmaceutical Co., Ltd. Crystal form of pyrroloquinoline quinone sodium salt and preparation method and use thereof
CN105218543B (zh) * 2015-11-02 2017-05-10 诸城市浩天药业有限公司 吡咯喹啉醌b晶型及其制备方法
CN105315278B (zh) * 2015-11-02 2018-01-16 诸城市浩天药业有限公司 吡咯喹啉醌a晶型及其制备方法
KR102838902B1 (ko) * 2018-08-30 2025-07-25 미쯔비시 가스 케미칼 컴파니, 인코포레이티드 광열화억제제, 그것을 포함하는 음료, 및 광열화억제방법
JP7301347B2 (ja) * 2019-05-22 2023-07-03 株式会社ブルーム・クラシック サーチュイン１活性化剤及びサーチュイン１活性化用皮膚化粧料
CN112125899B (zh) * 2019-06-24 2023-01-03 浙江可明生物医药有限公司 吡咯并喹啉醌二钠盐结晶、其制备方法及包含其的组合物
CN117327069B (zh) * 2023-09-27 2024-04-30 山东原力泰医药科技有限公司 吡咯并喹啉醌二钠盐晶型及其制备方法和应用

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3475969B2 (ja) 1993-08-27 2003-12-10 大日本インキ化学工業株式会社 共重合体樹脂エマルジョン、その製造方法及び防湿加工用組成物
US20070072894A1 (en) 2005-03-24 2007-03-29 Kempf J V Synthesis of pyrroloquinoline quinone (PQQ)
CN101193888A (zh) * 2005-03-24 2008-06-04 Clf医疗技术加速程序有限公司 吡咯喹啉醌（pqq）的合成方法
CN101885725A (zh) * 2009-05-12 2010-11-17 江苏道琪生物科技有限公司 吡咯喹啉醌钠盐衍生物及其制备方法
CN104744462B (zh) 2009-07-16 2016-09-21 三菱瓦斯化学株式会社 吡咯并喹啉醌的钠盐结晶、其制法、功能性食品和医药
US20120226045A1 (en) * 2009-11-06 2012-09-06 Mitsubishi Gas Chemical Company Inc. Pyrroloquinoline quinone in free form
JP5979376B2 (ja) * 2010-11-26 2016-08-24 三菱瓦斯化学株式会社 溶解性の高いピロロキノリンキノン塩及びその製造方法
DK2722331T3 (da) * 2011-06-16 2017-11-20 Mitsubishi Gas Chemical Co Pyrroloquinolinquinondinatriumsaltkrystal og fremgangsmåde til fremstilling af samme
JP2013112677A (ja) * 2011-12-01 2013-06-10 Mitsubishi Gas Chemical Co Inc ピロロキノリンキノンジナトリウム結晶
JP5962254B2 (ja) * 2012-06-27 2016-08-03 三菱瓦斯化学株式会社 高品質ピロロキノリンキノンの製造方法

Also Published As

Publication number Publication date
EP3131899A1 (fr) 2017-02-22
CN106255691A (zh) 2016-12-21
WO2015159236A1 (fr) 2015-10-22
US20170022200A1 (en) 2017-01-26
JP2017513863A (ja) 2017-06-01

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