MX2021006692A - Proceso mejorado para preparar ozanimod. - Google Patents

Proceso mejorado para preparar ozanimod.

Info

Publication number
MX2021006692A
MX2021006692A MX2021006692A MX2021006692A MX2021006692A MX 2021006692 A MX2021006692 A MX 2021006692A MX 2021006692 A MX2021006692 A MX 2021006692A MX 2021006692 A MX2021006692 A MX 2021006692A MX 2021006692 A MX2021006692 A MX 2021006692A
Authority
MX
Mexico
Prior art keywords
ozanimod
preparing
improved process
relates
salt
Prior art date
Application number
MX2021006692A
Other languages
English (en)
Inventor
Libor Vyklicky
Marian Buchlovic
Lenka Chalupova
Jiri Bartl
Original Assignee
Synthon Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Synthon Bv filed Critical Synthon Bv
Publication of MX2021006692A publication Critical patent/MX2021006692A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
    • C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
    • C07D271/06—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/18—Oxygen atoms
    • C07D263/20—Oxygen atoms attached in position 2
    • C07D263/22—Oxygen atoms attached in position 2 with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to other ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

La presente invención está relacionada con un proceso para la preparación de un compuesto de la fórmula (1) o una sal del mismo (es decir) ozanimod: (ver Fórmula), la invención también está relacionada con intermediarios usados en el proceso.
MX2021006692A 2018-12-07 2019-12-05 Proceso mejorado para preparar ozanimod. MX2021006692A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP18211127 2018-12-07
PCT/EP2019/083801 WO2020115200A1 (en) 2018-12-07 2019-12-05 Improved process for preparing ozanimod

Publications (1)

Publication Number Publication Date
MX2021006692A true MX2021006692A (es) 2021-07-07

Family

ID=64661219

Family Applications (1)

Application Number Title Priority Date Filing Date
MX2021006692A MX2021006692A (es) 2018-12-07 2019-12-05 Proceso mejorado para preparar ozanimod.

Country Status (5)

Country Link
US (1) US11390593B2 (es)
EP (1) EP3891133B1 (es)
ES (1) ES2962211T3 (es)
MX (1) MX2021006692A (es)
WO (1) WO2020115200A1 (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20220259163A1 (en) * 2019-07-16 2022-08-18 Synthon B.V. Improved process for preparing ozanimod

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EA035768B1 (ru) 2009-11-13 2020-08-07 Селджин Интернэшнел Ii Сарл Способ получения соединения, содержащего индановую группу с хиральным атомом углерода в пятичленном кольце индановой группы
CN108727292A (zh) 2017-04-21 2018-11-02 宁波爱诺医药科技有限公司 一种奥扎莫德及其中间体的制备方法
EP3630738B1 (en) 2017-05-22 2023-07-19 Egis Gyógyszergyár Zrt. Process for the production of ozanimod

Also Published As

Publication number Publication date
EP3891133A1 (en) 2021-10-13
ES2962211T3 (es) 2024-03-18
US20210363117A1 (en) 2021-11-25
EP3891133B1 (en) 2023-06-07
US11390593B2 (en) 2022-07-19
WO2020115200A1 (en) 2020-06-11

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