DK2722331T3 - Pyrroloquinolinquinondinatriumsaltkrystal og fremgangsmåde til fremstilling af samme - Google Patents
Pyrroloquinolinquinondinatriumsaltkrystal og fremgangsmåde til fremstilling af sammeInfo
- Publication number
- DK2722331T3 DK2722331T3 DK12800143.5T DK12800143T DK2722331T3 DK 2722331 T3 DK2722331 T3 DK 2722331T3 DK 12800143 T DK12800143 T DK 12800143T DK 2722331 T3 DK2722331 T3 DK 2722331T3
- Authority
- DK
- Denmark
- Prior art keywords
- making
- same
- disodium salt
- salt crystal
- pyrroloquinoline quinone
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/12—Ophthalmic agents for cataracts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/66—Preparation of oxygen-containing organic compounds containing the quinoid structure
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Ophthalmology & Optometry (AREA)
- Immunology (AREA)
- Pulmonology (AREA)
- Dermatology (AREA)
- Gastroenterology & Hepatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Cosmetics (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2011134279 | 2011-06-16 | ||
| PCT/JP2012/065303 WO2012173217A1 (ja) | 2011-06-16 | 2012-06-15 | ピロロキノリンキノンジナトリウム塩の結晶およびその製造方法 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK2722331T3 true DK2722331T3 (da) | 2017-11-20 |
Family
ID=47357196
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK12800143.5T DK2722331T3 (da) | 2011-06-16 | 2012-06-15 | Pyrroloquinolinquinondinatriumsaltkrystal og fremgangsmåde til fremstilling af samme |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US9174983B2 (da) |
| EP (1) | EP2722331B1 (da) |
| JP (1) | JPWO2012173217A1 (da) |
| CN (1) | CN103619842B (da) |
| DK (1) | DK2722331T3 (da) |
| ES (1) | ES2651238T3 (da) |
| NO (1) | NO2722331T3 (da) |
| PL (1) | PL2722331T3 (da) |
| WO (1) | WO2012173217A1 (da) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US9163014B2 (en) | 2009-07-16 | 2015-10-20 | Mitsubishi Gas Chemical Company, Inc. | Crystals of pyrroloquinolinequinone sodium salts |
| CN102942567B (zh) * | 2012-11-09 | 2017-02-08 | 诸城市浩天药业有限公司 | 吡咯并喹啉醌的二钠盐结晶 |
| MA39715A (fr) * | 2014-04-16 | 2015-10-22 | Anthem Biosciences Private Ltd | Formes polymorphes de l'acide 4,5-dihydro-1h-pyrrolo[2,3-f]quinoline-2,7,9-tricarboxylique et de son sel de disodium, procédé de préparation desdites formes polymorphes et leur utilisation |
| CN107207494B (zh) * | 2015-01-19 | 2020-01-21 | 三菱瓦斯化学株式会社 | 溶解性高的丙酮加成吡咯喹啉醌盐 |
| WO2017050171A1 (zh) | 2015-09-25 | 2017-03-30 | 浙江海正药业股份有限公司 | 吡咯并喹啉醌钠盐的晶型及其制备方法和用途 |
| JP6769705B2 (ja) * | 2015-11-30 | 2020-10-14 | 株式会社協和 | 胎盤抽出物の製造方法 |
| EP3480197B1 (en) * | 2016-06-29 | 2024-04-03 | Mitsubishi Gas Chemical Company, Inc. | Pyrroloquinone quinone monosodium, method for manufacturing same, and composition including same |
| KR102120670B1 (ko) * | 2019-01-03 | 2020-06-10 | 주식회사 누베파마 | 돌연변이 균주를 이용한 항산화 물질 생산 방법 |
| CN112125899B (zh) * | 2019-06-24 | 2023-01-03 | 浙江可明生物医药有限公司 | 吡咯并喹啉醌二钠盐结晶、其制备方法及包含其的组合物 |
| CN115716825A (zh) * | 2021-08-24 | 2023-02-28 | 浙江医药股份有限公司新昌制药厂 | 吡咯并喹啉醌二钠盐结晶、其制备方法及包含其的组合物 |
| CN117327069B (zh) * | 2023-09-27 | 2024-04-30 | 山东原力泰医药科技有限公司 | 吡咯并喹啉醌二钠盐晶型及其制备方法和应用 |
| CN117777147A (zh) * | 2024-02-23 | 2024-03-29 | 内蒙古金达威药业有限公司 | 一种吡咯并喹啉醌二钠盐的晶型及其制备方法 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH07113024B2 (ja) | 1986-04-17 | 1995-12-06 | 三菱瓦斯化学株式会社 | ピロロキノリンキノンの精製方法 |
| JP2751183B2 (ja) | 1988-02-26 | 1998-05-18 | 三菱瓦斯化学株式会社 | ピロロキノリンキノンの製造方法 |
| JP2692167B2 (ja) * | 1988-09-01 | 1997-12-17 | 三菱瓦斯化学株式会社 | ピロロキノリンキノン類の回収・精製方法 |
| JP3475969B2 (ja) | 1993-08-27 | 2003-12-10 | 大日本インキ化学工業株式会社 | 共重合体樹脂エマルジョン、その製造方法及び防湿加工用組成物 |
| NZ519984A (en) * | 2000-01-07 | 2004-03-26 | Transform Pharmaceuticals Inc | High-throughput formation, identification, and analysis of diverse solid-forms |
| US7276514B2 (en) | 2002-05-15 | 2007-10-02 | Charitable Leadership Foundation - Medical Technology Acceleration Program | Pyrroloquinoline quinone drugs for treatment of cardiac injury and methods of use thereof |
| JP2007269769A (ja) | 2006-03-10 | 2007-10-18 | Ultizyme International Ltd | 神経変性疾患関連蛋白質凝集線維化抑制剤 |
| US9163014B2 (en) | 2009-07-16 | 2015-10-20 | Mitsubishi Gas Chemical Company, Inc. | Crystals of pyrroloquinolinequinone sodium salts |
| JPWO2011055796A1 (ja) * | 2009-11-06 | 2013-03-28 | 三菱瓦斯化学株式会社 | ピロロキノリンキノンのフリー体 |
| JP2011098911A (ja) | 2009-11-06 | 2011-05-19 | Mitsubishi Gas Chemical Co Inc | ピロロキノリンキノン粉体 |
| JP2011246442A (ja) | 2010-04-28 | 2011-12-08 | Rohto Pharmaceutical Co Ltd | 光老化抑制剤および皮膚菲薄化抑制剤 |
-
2012
- 2012-06-15 WO PCT/JP2012/065303 patent/WO2012173217A1/ja active Application Filing
- 2012-06-15 JP JP2013520591A patent/JPWO2012173217A1/ja active Pending
- 2012-06-15 US US14/125,788 patent/US9174983B2/en active Active
- 2012-06-15 EP EP12800143.5A patent/EP2722331B1/en active Active
- 2012-06-15 NO NO12800143A patent/NO2722331T3/no unknown
- 2012-06-15 ES ES12800143.5T patent/ES2651238T3/es active Active
- 2012-06-15 DK DK12800143.5T patent/DK2722331T3/da active
- 2012-06-15 PL PL12800143T patent/PL2722331T3/pl unknown
- 2012-06-15 CN CN201280028888.9A patent/CN103619842B/zh active Active
Also Published As
| Publication number | Publication date |
|---|---|
| US20140128609A1 (en) | 2014-05-08 |
| EP2722331A4 (en) | 2014-11-05 |
| CN103619842B (zh) | 2016-06-22 |
| EP2722331A1 (en) | 2014-04-23 |
| WO2012173217A1 (ja) | 2012-12-20 |
| EP2722331B1 (en) | 2017-09-06 |
| PL2722331T3 (pl) | 2018-02-28 |
| NO2722331T3 (da) | 2018-02-03 |
| ES2651238T3 (es) | 2018-01-25 |
| JPWO2012173217A1 (ja) | 2015-02-23 |
| US9174983B2 (en) | 2015-11-03 |
| CN103619842A (zh) | 2014-03-05 |
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