SG11201801549VA - Pluripotent stem cell production system - Google Patents

Pluripotent stem cell production system

Info

Publication number
SG11201801549VA
SG11201801549VA SG11201801549VA SG11201801549VA SG11201801549VA SG 11201801549V A SG11201801549V A SG 11201801549VA SG 11201801549V A SG11201801549V A SG 11201801549VA SG 11201801549V A SG11201801549V A SG 11201801549VA SG 11201801549V A SG11201801549V A SG 11201801549VA
Authority
SG
Singapore
Prior art keywords
stem cell
production system
pluripotent stem
cell production
pluripotent
Prior art date
Application number
SG11201801549VA
Other languages
English (en)
Inventor
Brendan Kelly
Kenta Suto
Koji Tanabe
Hidenori Shimoda
Ryoji Hiraide
Original Assignee
I Peace Inc
Koji Tanabe
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by I Peace Inc, Koji Tanabe filed Critical I Peace Inc
Publication of SG11201801549VA publication Critical patent/SG11201801549VA/en

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/48—Automatic or computerized control
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/28—Constructional details, e.g. recesses, hinges disposable or single use
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M23/00—Constructional details, e.g. recesses, hinges
    • C12M23/44—Multiple separable units; Modules
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M27/00—Means for mixing, agitating or circulating fluids in the vessel
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/04—Filters; Permeable or porous membranes or plates, e.g. dialysis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M35/00—Means for application of stress for stimulating the growth of microorganisms or the generation of fermentation or metabolic products; Means for electroporation or cell fusion
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M37/00—Means for sterilizing, maintaining sterile conditions or avoiding chemical or biological contamination
    • C12M37/02—Filters
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/12—Means for regulation, monitoring, measurement or control, e.g. flow regulation of temperature
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
    • C12M41/30—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration
    • C12M41/36—Means for regulation, monitoring, measurement or control, e.g. flow regulation of concentration of biomass, e.g. colony counters or by turbidity measurements
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M45/00—Means for pre-treatment of biological substances
    • C12M45/02—Means for pre-treatment of biological substances by mechanical forces; Stirring; Trituration; Comminuting
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M47/00—Means for after-treatment of the produced biomass or of the fermentation or metabolic products, e.g. storage of biomass
    • C12M47/04—Cell isolation or sorting
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0696—Artificially induced pluripotent stem cells, e.g. iPS

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Sustainable Development (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Molecular Biology (AREA)
  • Clinical Laboratory Science (AREA)
  • Thermal Sciences (AREA)
  • Hematology (AREA)
  • Computer Hardware Design (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Mechanical Engineering (AREA)
  • Developmental Biology & Embryology (AREA)
  • Transplantation (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Peptides Or Proteins (AREA)
SG11201801549VA 2015-08-31 2016-08-31 Pluripotent stem cell production system SG11201801549VA (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2015170797 2015-08-31
US201662356199P 2016-06-29 2016-06-29
PCT/JP2016/075540 WO2017038887A1 (ja) 2015-08-31 2016-08-31 多能性幹細胞製造システム

Publications (1)

Publication Number Publication Date
SG11201801549VA true SG11201801549VA (en) 2018-03-28

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
SG11201801549VA SG11201801549VA (en) 2015-08-31 2016-08-31 Pluripotent stem cell production system

Country Status (7)

Country Link
US (5) US11286454B2 (enExample)
EP (4) EP3344755A4 (enExample)
JP (7) JP7370529B2 (enExample)
CN (5) CN114717183B (enExample)
CA (2) CA2996582A1 (enExample)
SG (1) SG11201801549VA (enExample)
WO (2) WO2017040548A1 (enExample)

Families Citing this family (55)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP7370529B2 (ja) 2015-08-31 2023-10-30 剛士 田邊 多能性幹細胞製造システム、幹細胞の誘導方法、幹細胞の浮遊培養方法、幹細胞の浮遊培養器、人工多能性幹細胞の作製方法、及び動物細胞から特定の体細胞を作製する方法
CA3044251A1 (en) * 2016-11-18 2018-05-24 New York Stem Cell Foundation, Inc. Microfluidic system and method of use thereof
EP3556842A4 (en) * 2017-01-20 2020-01-15 FUJIFILM Corporation CELL CULTURE APPARATUS AND METHOD
JP6998018B2 (ja) 2017-02-24 2022-01-18 剛士 田邊 細胞処理装置、浮遊培養器、及び幹細胞の誘導方法
CN110352238A (zh) 2017-02-24 2019-10-18 田边刚士 诱导性多能干细胞的制作方法
CN110392733B (zh) * 2017-02-27 2021-02-26 田边刚士 体细胞制造系统
CA3054272C (en) * 2017-02-27 2023-01-24 I Peace, Inc. Cell processing system and cell processing apparatus
WO2018218105A1 (en) * 2017-05-26 2018-11-29 Kite Pharma, Inc. Methods of making and using embryonic mesenchymal progenitor cells
WO2019040915A1 (en) * 2017-08-24 2019-02-28 Terumo Bct, Inc. CELL EXPANSION
EP3680324A4 (en) * 2017-09-08 2021-06-16 Otsuka Pharmaceutical Factory, Inc. Stem cells derived from young pig and preparation method therefor
WO2019131626A1 (ja) * 2017-12-28 2019-07-04 オリンパス株式会社 細胞培養制御方法、細胞培養制御装置、細胞培養装置および細胞培養システム
US11932842B2 (en) 2018-02-09 2024-03-19 Global Life Sciences Solutions Usa Llc Bioprocessing apparatus
US10889792B2 (en) 2018-02-09 2021-01-12 Global Life Sciences Solutions Usa Llc Cell expansion vessel systems and methods
US11920119B2 (en) 2018-02-09 2024-03-05 Global Life Sciences Solutions Usa Llc Systems and methods for bioprocessing
US12252682B2 (en) 2018-02-09 2025-03-18 Global Life Sciences Solutions Usa Llc System and method for fluid flow management in a bioprocessing system
US12077743B2 (en) 2018-02-09 2024-09-03 Global Life Sciences Solutions Usa Llc Apparatus for fluid line management in a bioprocessing system
CN111971382A (zh) * 2018-02-09 2020-11-20 环球生命科技咨询美国有限责任公司 用于细胞疗法的生物处理方法
JP6939643B2 (ja) * 2018-02-26 2021-09-22 株式会社Ihi 細胞分割装置及び細胞培養装置
EP3810749A4 (en) * 2018-06-19 2022-04-20 Stemcell Technologies Canada Inc. SYSTEMS, METHODS AND APPARATUS FOR AUTOMATED CELL CULTURE
WO2020017411A1 (ja) * 2018-07-17 2020-01-23 国立大学法人神戸大学 固液界面検出装置及びこれを備えた前処理装置
WO2020021860A1 (ja) 2018-07-24 2020-01-30 富士フイルム株式会社 細胞培養支援装置の作動プログラム、細胞培養支援装置、細胞培養支援装置の作動方法
CN112567016A (zh) * 2018-08-20 2021-03-26 爱平世股份有限公司 细胞培养器
US20210198635A1 (en) * 2018-08-20 2021-07-01 I Peace, Inc. Cell culture or induction method
WO2020044984A1 (ja) * 2018-08-27 2020-03-05 富士フイルム株式会社 細胞培養方法及び細胞培養装置
SG11202108505XA (en) * 2019-02-05 2021-09-29 Corning Inc Woven cell culture substrates
JP2020167959A (ja) * 2019-04-04 2020-10-15 オリンパス株式会社 培地モニタリング装置
JP7416764B2 (ja) * 2019-03-25 2024-01-17 テルモ株式会社 細胞培養物を清浄度の高い空間において調製するための容器及びキット
WO2020196649A1 (ja) * 2019-03-27 2020-10-01 株式会社カネカ 細胞製造装置、細胞製造方法並びにこれに用いられるサーバ、システムおよび装置
CN110066733A (zh) * 2019-05-29 2019-07-30 广东唯泰生物科技有限公司 干细胞培养机器人
JP7343881B2 (ja) * 2019-06-10 2023-09-13 アイ ピース，インコーポレイテッド 赤血球除去装置、単核球回収器、細胞培養装置、細胞培養システム、細胞培養方法、及び単核球の回収方法
CN113795571A (zh) * 2019-06-28 2021-12-14 爱平世股份有限公司 细胞团分割器、细胞团分割器的制造方法、以及细胞团的分割方法
WO2020262354A1 (ja) * 2019-06-28 2020-12-30 アイ ピース， インコーポレイテッド 細胞培養器及び細胞培養装置
CN110229751A (zh) * 2019-07-17 2019-09-13 中国人民解放军军事科学院军事医学研究院 mRNA制备系统及制备方法
US20230038829A1 (en) * 2019-08-29 2023-02-09 Fanuc Corporation Cell production device and cell production method
EP4023747A4 (en) * 2019-08-29 2023-11-08 Fanuc Corporation CELL PRODUCTION APPARATUS AND SYSTEM THEREOF
JP7297272B2 (ja) * 2019-08-29 2023-06-26 ファナック株式会社 細胞製造装置
US11118151B2 (en) 2019-11-05 2021-09-14 Corning Incorporated Fixed bed bioreactor and methods of using the same
JP7656868B2 (ja) * 2019-11-06 2025-04-04 アイ ピース，インコーポレイテッド 細胞培養装置
CN111126329A (zh) * 2019-12-30 2020-05-08 杭州原生生物科技有限公司 一种自动识别多能干细胞群的方法
WO2021166227A1 (ja) * 2020-02-21 2021-08-26 アイ ピース， インコーポレイテッド 溶液搬送装置
CN116134125A (zh) * 2020-05-22 2023-05-16 Sqz生物技术公司 用于自动处理细胞的即时医疗系统
CN111666895B (zh) * 2020-06-08 2023-05-26 上海市同济医院 基于深度学习的神经干细胞分化方向预测系统及方法
JP7682619B2 (ja) * 2020-10-19 2025-05-26 キヤノンメディカルシステムズ株式会社 誘導多能性幹細胞樹立装置及び方法
EP4267713A4 (en) * 2020-12-23 2025-03-05 Cedars-Sinai Medical Center METHOD FOR DIFFERENTIATION OF EXOCRINE PANCREAS CELLS FROM HUMAN INDUCED PLURIPOTENT STEM CELLS
JP7744155B2 (ja) * 2021-04-19 2025-09-25 キヤノンメディカルシステムズ株式会社 多能性幹細胞製造システム
WO2022244670A1 (ja) * 2021-05-18 2022-11-24 国立大学法人京都大学 多能性幹細胞の製造方法
CN113265333A (zh) * 2021-06-23 2021-08-17 无锡生基医药科技有限公司 一种全封闭、半自动化控制、模块化的质粒瞬时转染系统
US20240336897A1 (en) * 2021-08-28 2024-10-10 Cornell University Compositions and methods for cell reprogramming
WO2023053220A1 (ja) * 2021-09-28 2023-04-06 公益財団法人京都大学ｉＰＳ細胞研究財団 多能性幹細胞の製造方法
US20230130734A1 (en) * 2021-10-27 2023-04-27 Regenerative Research Foundation Cell culture feeding device
CN120283047A (zh) * 2022-12-15 2025-07-08 雅马哈发动机株式会社 产生重组蛋白质的细胞的培养方法
WO2024176440A1 (ja) * 2023-02-24 2024-08-29 公益財団法人京都大学ｉＰＳ細胞研究財団 人工多能性幹細胞の製造方法
CN116426573A (zh) * 2023-04-14 2023-07-14 臻赫医药(杭州)有限公司 重编程因子抗衰老表达系统、生物材料及用途
WO2025121328A1 (ja) * 2023-12-04 2025-06-12 公益財団法人京都大学ｉＰＳ細胞研究財団 人工多能性幹細胞の製造方法
CN118460359B (zh) * 2024-07-10 2024-09-20 江苏颐泽生物科技有限公司 一种具有细胞活性检测功能的干细胞贮存装置

Family Cites Families (71)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3788026T2 (de) * 1986-08-27 1994-04-21 Kawasumi Lab Inc Verfahren und Vorrichtung zur Kultivierung von Zellen.
US5399493A (en) * 1989-06-15 1995-03-21 The Regents Of The University Of Michigan Methods and compositions for the optimization of human hematopoietic progenitor cell cultures
JP3630493B2 (ja) * 1995-03-20 2005-03-16 プレシジョン・システム・サイエンス株式会社 分注機を利用した液体処理方法およびその装置
CA2263226C (en) 1996-08-16 2006-10-10 Imaging Research, Inc. A digital imaging system for assays in well plates, gels and blots
TWI288779B (en) 2002-03-28 2007-10-21 Blasticon Biotech Forschung Dedifferentiated, programmable stem cells of monocytic origin, and their production and use
JP4309815B2 (ja) 2004-07-05 2009-08-05 株式会社日立製作所 細胞培養システム及び細胞培養方法
CA2593374A1 (en) 2004-12-29 2006-07-06 Biogen Idec Ma Inc. Bioreactor process control system and method
CN100335612C (zh) * 2005-01-20 2007-09-05 上海交通大学 植物细胞或组织两段连续培养系统
CN1664545A (zh) * 2005-03-18 2005-09-07 宁波美生医疗器材有限公司 一种细胞薄层涂片的制作方法
JP2007000038A (ja) 2005-06-22 2007-01-11 Toray Ind Inc 閉鎖系循環回路型培養装置
CN2841667Y (zh) * 2005-09-09 2006-11-29 刘平 细胞滤过器
US20070087437A1 (en) * 2005-10-14 2007-04-19 Jifan Hu Methods for rejuvenating cells in vitro and in vivo
CN101356270B (zh) 2005-12-13 2014-02-12 国立大学法人京都大学 核重新编程因子
CN101796181A (zh) * 2007-05-04 2010-08-04 埃里克·松德斯特伦 切割装置
JP2008307007A (ja) * 2007-06-15 2008-12-25 Bayer Schering Pharma Ag 出生後のヒト組織由来未分化幹細胞から誘導したヒト多能性幹細胞
KR20100059789A (ko) 2007-06-29 2010-06-04 셀룰러 다이내믹스 인터내셔널, 인코포레이티드 배아줄기세포 배양을 위한 자동화 방법 및 장치
US7858371B2 (en) * 2007-09-26 2010-12-28 Weyerhaeuser Nr Company Method of separating embryo suspension mass
US9683232B2 (en) * 2007-12-10 2017-06-20 Kyoto University Efficient method for nuclear reprogramming
JP5385304B2 (ja) 2008-01-09 2014-01-08 スクリーンセル 生きた細胞をフィルタ上で分離して培養するまたはその細胞の遺伝子材料を抽出するための装置と方法
KR101481164B1 (ko) * 2008-01-30 2015-01-09 주식회사 미래셀바이오 체세포 유래 다능성 줄기세포의 제조 방법
EP2315829B1 (en) * 2008-08-08 2015-02-11 Mayo Foundation For Medical Education And Research Induced pluripotent stem cells
ES2561949T3 (es) * 2008-11-21 2016-03-01 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. Reprogramación de células hacia un estado pluripotente
US20120196358A1 (en) 2009-06-01 2012-08-02 Fred Burbank Device for removing cumulus from oocytes
CA2952805C (en) * 2009-06-05 2021-06-01 Cellular Dynamics International, Inc. Reprogramming t cells and hematopoietic cells
CN102686717B (zh) 2009-10-09 2014-10-29 佐治亚科技研究公司 用于分散生物材料聚结体的方法和设备
EP4166652A1 (en) * 2009-11-12 2023-04-19 Technion Research & Development Foundation Ltd. Culture media, cell cultures and methods of culturing pluripotent stem cells in an undifferentiated state
JP5791634B2 (ja) * 2010-01-29 2015-10-07 マイクロニクス， インコーポレイテッド サンプル−回答型のマイクロ流体カートリッジ
EP2558571A4 (en) * 2010-04-16 2014-09-24 Immune Disease Inst Inc DELAYED POLYPEPTIDE EXPRESSION FROM MODIFIED SYNTHETIC RNAS AND USES THEREOF
US8048675B1 (en) 2010-05-12 2011-11-01 Ipierian, Inc. Integration-free human induced pluripotent stem cells from blood
EP2603517B1 (en) * 2010-05-12 2023-07-19 Cellectis Dynamic mixing and electroporation chamber and system
US10214722B2 (en) * 2010-09-07 2019-02-26 Technion Research & Development Foundation Limited Methods for expanding and maintaining human pluripotent stem cells (PSCs) in an undifferentiated state in a single cell suspension culture
US20160272934A1 (en) * 2010-10-08 2016-09-22 Cellanyx Diagnostics, Llc Systems, devices and methods for microfluidic culturing, manipulation and analysis of tissues and cells
CN102559587A (zh) * 2010-12-16 2012-07-11 中国科学院上海药物研究所 诱导性多能干细胞的制备方法以及用于制备诱导性多能干细胞的培养基
KR102482184B1 (ko) * 2010-12-22 2022-12-28 페이트 세러퓨틱스, 인코포레이티드 단세포 분류 및 iPSC의 증강된 재프로그래밍을 위한 세포 배양 플랫폼
CN102174395B (zh) 2011-01-30 2013-08-21 中国科学院广州生物医药与健康研究院 诱导多能干细胞自动化扩增与培养系统
WO2012115153A1 (ja) 2011-02-25 2012-08-30 株式会社ニコン 細胞評価方法、細胞培養方法、細胞評価装置、インキュベータ、細胞評価プログラム、コロニー分類プログラム、幹細胞の培養方法、幹細胞評価装置および幹細胞評価プログラム
GB201105413D0 (en) * 2011-03-30 2011-05-11 Cambridge Entpr Ltd Nuclear reprogramming substrate
EP2697357A4 (en) * 2011-04-15 2015-04-22 Univ British Columbia METHOD AND DEVICE FOR SEPARATING PARTICLES
RU2656156C2 (ru) 2011-10-17 2018-05-31 Массачусетс Инститьют Оф Текнолоджи Внутриклеточная доставка
WO2013058403A1 (ja) 2011-10-21 2013-04-25 国立大学法人京都大学 層流による多能性維持単一分散細胞培養法
EP2594632A1 (en) * 2011-11-18 2013-05-22 Miltenyi Biotec GmbH Method and device for cell modification
EP2784153B1 (en) * 2011-11-25 2018-01-03 Kyoto University Method for culturing pluripotent stem cell
US10428309B2 (en) * 2011-12-01 2019-10-01 New York Stem Cell Foundation, Inc. Systems and methods for producing stem cells and differentiated cells
JP6257520B2 (ja) * 2011-12-01 2018-01-10 ニューヨーク ステム セル ファウンデーション インコーポレイテッド 人工多能性幹細胞または分化細胞を作製するための自動化されたシステム
CA2858117A1 (en) * 2011-12-15 2013-06-20 Dow Agrosciences Llc Method for improved transformation using agrobacterium
WO2013094365A1 (ja) 2011-12-22 2013-06-27 三洋電機株式会社 観察システム、プログラム及び観察システムの制御方法
JP5991368B2 (ja) 2012-03-16 2016-09-14 株式会社日立製作所 細胞シート、細胞培養方法および細胞培養装置
WO2013177228A1 (en) * 2012-05-22 2013-11-28 Loma Linda University Generation of integration/transgene-free stem cells
CA2876868A1 (en) 2012-06-13 2013-12-19 Stemgent, Inc. Methods of preparing pluripotent stem cells
DK2878664T3 (en) 2012-07-24 2018-11-05 Nissan Chemical Corp CULTURE MEDIUM COMPOSITION AND PROCEDURE FOR CULTIVATING CELLS OR TISSUE USING THE COMPOSITION
US9664671B2 (en) * 2012-07-24 2017-05-30 Nissan Chemical Industries, Ltd. Culture medium composition and method of culturing cell or tissue using thereof
WO2014072061A1 (en) 2012-11-09 2014-05-15 Biontech Ag Method for cellular rna expression
EP2966163B1 (en) 2013-03-06 2018-01-17 Kyoto University Culture system for pluripotent stem cells and method for subculturing pluripotent stem cells
EP2970881A4 (en) * 2013-03-14 2017-01-25 Children's Medical Center Corporation Compositions and methods for reprogramming hematopoietic stem cell lineages
US10578633B2 (en) * 2013-03-15 2020-03-03 Fluidigm Corporation Methods and devices for analysis of defined multicellular combinations
US10519421B2 (en) 2013-03-21 2019-12-31 Kyoto University Induction of motor neurons from pluripotent stem cells
JP6319304B2 (ja) * 2013-04-17 2018-05-09 日産化学工業株式会社 培地組成物及び当該培地組成物を用いた赤血球の製造方法
US20150159127A1 (en) * 2013-05-10 2015-06-11 BioCapacity On Demand, LLC Mobile vessel or carrier for the manufacturing production, purification and sterile fill and finish of biologics
JP2016520288A (ja) * 2013-06-11 2016-07-14 国立大学法人京都大学 効率的な人工多能性幹細胞の樹立方法
US9580678B2 (en) * 2013-06-21 2017-02-28 The Regents Of The University Of California Microfluidic tumor tissue dissociation device
US9765296B2 (en) 2013-09-04 2017-09-19 Otsuka Pharmaceutical Factory, Inc. Method for preparing pluripotent stem cells
JP5751726B2 (ja) 2013-11-12 2015-07-22 東京エレクトロン株式会社 多能性幹細胞の培養方法及び施設
SG11201606056RA (en) 2014-01-23 2016-08-30 Nissan Chemical Ind Ltd Culture medium composition
KR102282265B1 (ko) 2014-01-23 2021-07-26 닛산 가가쿠 가부시키가이샤 배양 배지 조성물의 제조 방법
US10100286B2 (en) * 2014-06-20 2018-10-16 The Board Of Trustees Of The University Of Alabama Systems and methods of dissociating aggregate spheres of cells
US20170355950A1 (en) * 2014-12-04 2017-12-14 The Arizona Board Of Regents On Behalf Of The University Of Arizona Systems for dissociation of biological tissues
JP6291429B2 (ja) 2015-01-20 2018-03-14 富士フイルム株式会社 細胞培養装置および細胞培養方法
JP6734283B2 (ja) * 2015-01-21 2020-08-05 フレッド ハッチンソン キャンサー リサーチ センター 遺伝子治療用ポイントオブケア及び／又はポータブルプラットフォーム
WO2016143826A1 (ja) 2015-03-09 2016-09-15 学校法人慶應義塾 多能性幹細胞を所望の細胞型へ分化する方法
JP7370529B2 (ja) 2015-08-31 2023-10-30 剛士 田邊 多能性幹細胞製造システム、幹細胞の誘導方法、幹細胞の浮遊培養方法、幹細胞の浮遊培養器、人工多能性幹細胞の作製方法、及び動物細胞から特定の体細胞を作製する方法
BR112018075194B1 (pt) * 2016-06-08 2023-01-10 The Regents Of The University Of California Método e dispositivo para processar amostras

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