SE9402595L - Förfarande för kristallisation av iopamidol - Google Patents
Förfarande för kristallisation av iopamidolInfo
- Publication number
- SE9402595L SE9402595L SE9402595A SE9402595A SE9402595L SE 9402595 L SE9402595 L SE 9402595L SE 9402595 A SE9402595 A SE 9402595A SE 9402595 A SE9402595 A SE 9402595A SE 9402595 L SE9402595 L SE 9402595L
- Authority
- SE
- Sweden
- Prior art keywords
- iopamidol
- crystallization
- pharmacopoeia
- butanol
- purifying
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/22—Separation; Purification; Stabilisation; Use of additives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/28—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton
- C07C237/46—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atom of at least one of the carboxamide groups bound to a carbon atom of a non-condensed six-membered aromatic ring of the carbon skeleton having carbon atoms of carboxamide groups, amino groups and at least three atoms of bromine or iodine, bound to carbon atoms of the same non-condensed six-membered aromatic ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITMI931720A IT1257001B (it) | 1993-07-30 | 1993-07-30 | Processo per la cristalizzazione dello iopamidolo |
IT000760 IT1269339B (it) | 1994-04-20 | 1994-04-20 | Processo per la cristallizzazione dello iopamidolo |
Publications (2)
Publication Number | Publication Date |
---|---|
SE9402595D0 SE9402595D0 (sv) | 1994-07-29 |
SE9402595L true SE9402595L (sv) | 1995-01-31 |
Family
ID=26331032
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE9402595A SE9402595L (sv) | 1993-07-30 | 1994-07-29 | Förfarande för kristallisation av iopamidol |
Country Status (29)
Country | Link |
---|---|
US (3) | US5571941A (da) |
JP (1) | JP3299045B2 (da) |
KR (1) | KR100355211B1 (da) |
CN (1) | CN1035940C (da) |
AT (1) | AT404832B (da) |
AU (1) | AU690138B2 (da) |
BE (1) | BE1008403A4 (da) |
CA (1) | CA2128942C (da) |
CH (1) | CH686783A5 (da) |
CZ (1) | CZ289300B6 (da) |
DE (1) | DE4426818A1 (da) |
DK (1) | DK172074B1 (da) |
ES (1) | ES2102312B1 (da) |
FI (1) | FI960400A0 (da) |
FR (1) | FR2708601B1 (da) |
GB (1) | GB2280436B (da) |
GR (1) | GR940100366A (da) |
HU (1) | HU217023B (da) |
IE (1) | IE80675B1 (da) |
IL (1) | IL110391A (da) |
NL (1) | NL194272C (da) |
NO (1) | NO304226B1 (da) |
NZ (1) | NZ271632A (da) |
PT (1) | PT101554B (da) |
RU (1) | RU2135462C1 (da) |
SE (1) | SE9402595L (da) |
SI (1) | SI9420046B (da) |
WO (1) | WO1995004031A1 (da) |
ZA (1) | ZA945472B (da) |
Families Citing this family (19)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL110391A (en) | 1993-07-30 | 1998-12-06 | Zambon Spa | Process for the formation of infamidol |
US6310243B1 (en) * | 1994-09-23 | 2001-10-30 | Nycomed Imaging As | Iodinated x-ray contrast media |
PT101720A (pt) * | 1995-06-08 | 1997-01-31 | Hovione Sociedade Quimica S A | Processo para a purificacao e cristalizacao de iopamidol |
EP0842141A1 (en) * | 1995-07-04 | 1998-05-20 | RECORDATI S.A. CHEMICAL and PHARMACEUTICAL COMPANY | A process for preparing iopamidol by using a c1-c5 monoalkylether of a c2-c10 alkylen-glycol |
ATE187437T1 (de) * | 1995-09-08 | 1999-12-15 | Bracco Int Bv | Verfahren zur kristallisierung aus wasser von (s)-n,n'-bis(2-hydroxy-1-(hydroxymethiel)ethyl> 5-((2-hydroxy-1-oxopropyl)amino>-2,4,6-triiodo- ,3- benzoldicarboxamide |
PT101919B (pt) * | 1996-09-30 | 2000-01-31 | Hovione Sociedade Quimica Sa | Um processo para a purificacao de tohexol |
KR100758741B1 (ko) * | 1997-02-11 | 2007-09-14 | 브라코 인터내셔날 비이.브이. | 선형 또는 분지형 (c5-c6) 알콜 또는 그의 혼합물로부터 (s)-n,n'-비스[2-히드록시-1-(히드록시메틸)에틸]-5-[(2-히드록시-1-옥소프로필)아미노]-2,4,6-트리요오도-1,3-벤젠디카르복스아미드의 결정화 방법 |
GB9720969D0 (en) * | 1997-10-02 | 1997-12-03 | Nycomed Imaging As | Process |
KR20000031642A (ko) * | 1998-11-09 | 2000-06-05 | 강재헌 | 이오파미돌의 결정화 방법 |
US6265610B1 (en) | 1999-01-12 | 2001-07-24 | The University Of North Carolina At Chapel Hill | Contrast media for angiography |
US6803485B2 (en) | 1999-02-26 | 2004-10-12 | Bracco Imaging S.P.A. | Process for the preparation of iopamidol |
IT1319671B1 (it) | 2000-12-01 | 2003-10-23 | Bracco Spa | Processo per la preparazione di (s)-n,n'-bis(2-idrossi-1-(idrossimetil)etil)-5-((2-idrossi-1-ossopropil)ammino) |
DE102005059191B4 (de) * | 2005-12-05 | 2008-02-07 | Bayer Schering Pharma Ag | Verfahren zur Rückgewinnung von für pharmazeutische Zwecke geeignetem Iopromid aus Mutterlaugen |
KR100976097B1 (ko) * | 2008-12-05 | 2010-08-16 | 주식회사 대웅제약 | 이오프로마이드의 z 이성체를 선택적으로 결정화하는 방법 |
AU2010232556A1 (en) * | 2009-04-02 | 2011-11-03 | Allergan, Inc. | Prostaglandin E receptor antagonists |
WO2012136813A2 (en) | 2011-04-07 | 2012-10-11 | Universitetet I Oslo | Agents for medical radar diagnosis |
DE102012104679A1 (de) | 2011-05-30 | 2012-12-06 | Westfälische Wilhelms-Universität Münster | Biotechnologische konversion von glycerin zu 2-amino-1,3-propandiol (serinol) in rekombinanten escherichia coli |
CN104854080B (zh) * | 2012-12-19 | 2018-07-03 | 通用电气医疗集团股份有限公司 | X-射线造影剂的纯化 |
KR102128423B1 (ko) * | 2018-09-17 | 2020-07-01 | (주)유케이케미팜 | 조영제 이오메프롤의 제조방법 |
Family Cites Families (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH608189A5 (da) * | 1974-12-13 | 1978-12-29 | Savac Ag | |
GB1548594A (en) * | 1976-06-11 | 1979-07-18 | Nyegaard & Co As | Triiodoisophthalic acid amides |
IT1193211B (it) * | 1979-08-09 | 1988-06-15 | Bracco Ind Chimica Spa | Derivati dell'acido 2,4,6-triiodo-isoftalico,metodo per la loro preparazione e mezzi di contrasto che li contengono |
DE3150916A1 (de) * | 1981-12-18 | 1983-06-30 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | N-hydroxyaethylierte 2,4,6-trijodaminoisiophthalsaeure-bis- trihydroxybutylamide, deren herstellung und diese enthaltende roentgenkontrastmittel" |
US5204086A (en) * | 1982-10-01 | 1993-04-20 | Nycomed Imaging As | X-ray contrast agent |
NZ224743A (en) * | 1987-05-22 | 1991-07-26 | Bracco Ind Chimica Spa | 5-acylamino-2,4,6-tribromo- or triiodo-benzoic acid derivatives and intermediate compounds used in their preparation |
IT1248741B (it) * | 1991-02-26 | 1995-01-26 | Bracco Spa | Processo di concentrazione e di purificazione di composti organici |
IL110391A (en) | 1993-07-30 | 1998-12-06 | Zambon Spa | Process for the formation of infamidol |
-
1994
- 1994-07-20 IL IL11039194A patent/IL110391A/en not_active IP Right Cessation
- 1994-07-22 WO PCT/EP1994/002415 patent/WO1995004031A1/en active Application Filing
- 1994-07-22 RU RU96105070A patent/RU2135462C1/ru active
- 1994-07-22 HU HU9600191A patent/HU217023B/hu unknown
- 1994-07-22 CN CN94192930A patent/CN1035940C/zh not_active Expired - Lifetime
- 1994-07-22 SI SI9420046A patent/SI9420046B/sl unknown
- 1994-07-22 KR KR1019960700580A patent/KR100355211B1/ko not_active IP Right Cessation
- 1994-07-22 NZ NZ271632A patent/NZ271632A/en not_active IP Right Cessation
- 1994-07-22 GR GR940100366A patent/GR940100366A/el unknown
- 1994-07-22 AU AU75321/94A patent/AU690138B2/en not_active Expired
- 1994-07-25 GB GB9414912A patent/GB2280436B/en not_active Expired - Lifetime
- 1994-07-25 ZA ZA945472A patent/ZA945472B/xx unknown
- 1994-07-26 CH CH02354/94A patent/CH686783A5/it not_active IP Right Cessation
- 1994-07-26 NL NL9401229A patent/NL194272C/nl not_active IP Right Cessation
- 1994-07-26 PT PT101554A patent/PT101554B/pt not_active IP Right Cessation
- 1994-07-26 FR FR9409238A patent/FR2708601B1/fr not_active Expired - Lifetime
- 1994-07-27 CA CA002128942A patent/CA2128942C/en not_active Expired - Lifetime
- 1994-07-28 DE DE4426818A patent/DE4426818A1/de not_active Ceased
- 1994-07-29 JP JP17811594A patent/JP3299045B2/ja not_active Expired - Lifetime
- 1994-07-29 DK DK089294A patent/DK172074B1/da not_active IP Right Cessation
- 1994-07-29 CZ CZ19941831A patent/CZ289300B6/cs not_active IP Right Cessation
- 1994-07-29 SE SE9402595A patent/SE9402595L/xx not_active Application Discontinuation
- 1994-07-29 ES ES09401679A patent/ES2102312B1/es not_active Expired - Fee Related
- 1994-07-29 AT AT0150594A patent/AT404832B/de not_active IP Right Cessation
- 1994-07-29 BE BE9400717A patent/BE1008403A4/fr not_active IP Right Cessation
- 1994-07-29 IE IE940609A patent/IE80675B1/en not_active IP Right Cessation
- 1994-07-29 US US08/281,985 patent/US5571941A/en not_active Ceased
-
1996
- 1996-01-29 FI FI960400A patent/FI960400A0/fi not_active Application Discontinuation
- 1996-01-29 NO NO960376A patent/NO304226B1/no not_active IP Right Cessation
-
1997
- 1997-02-07 US US08/797,610 patent/USRE36433E/en not_active Expired - Lifetime
-
1998
- 1998-08-25 US US09/139,894 patent/US6506938B1/en not_active Expired - Lifetime
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
SE9402595L (sv) | Förfarande för kristallisation av iopamidol | |
ES2124373T3 (es) | Procedimiento para la preparacion de derivados del acido n-acil-n,n',n'-etilendiamintriacetico. | |
FI930377A (fi) | Reducering kvaeveoxider under anvaendning av ureahydrolysat | |
RU95114376A (ru) | Нитроэфиры, обладающие фармакологической активностью, и способ их получения | |
ES2157254T3 (es) | Ceftiofur (acido libre) cristalino. | |
ES2154266T3 (es) | Amidas de acido sulfonamidocarbonilpiridin-2-carboxilico y su empleo como medicamentos. | |
RU94042397A (ru) | Композиция для получения волокон или пленок на основе формата целлюлозы, способ получения волокна из регенерированной целлюлозы и регенерированное целлюлозное волокно | |
ATE121086T1 (de) | Sulfonylbenzyl-substituierte benzo- und pyridopyridone. | |
DE69423179D1 (de) | Prozess zur Herstellung von optisch aktiven 2-Amino-1-phenylethanol Derivaten | |
MX9203011A (es) | Procedimiento para preparar una solucion acuosa de fragmento de factor de von willebrand alterado con cisteina y solucion terapeutica fundida mediante el mismo | |
EP0362520A3 (de) | Ein neues Antibiotikum, Mersacidin, ein Verfahren zur seiner Herstellung und seine Verwendung als Arzneimittel | |
ZA834090B (en) | Ester of metronidazole with n,n-dimethylglycine and acid addition salt thereof | |
DE69429224T2 (de) | Zwischenprodukte für die Synthese von Cephalosporinen | |
DK0633924T3 (da) | Anvendelse af rengøringsmidler til hårde overflader, især glas | |
DE69109207D1 (de) | Verfahren zur Herstellung von kleinen röhrenförmigen Lampen. | |
PT1194398E (pt) | Sintese de aminocarnitina (s) e (r) e dos seus derivados, a partir de acido aspartico l e d | |
MX9207468A (es) | Proceso para preparar acido 2,6-naftalenodicarboxilico purificado. | |
ATE213234T1 (de) | Verfahren zur herstellung von 3-amino-1,2,4- benzotriazindioxide | |
DE68918849D1 (de) | Kristalline (5r,6s)-2-carbamoyloxymethyl-6-[(1r)-hydroxyäthyl]-2-penem-3-carbonsäure und ihre pharmazeutische präparate. | |
WO1998023574A8 (en) | Asiatic acid derivatives and medicines for treating wounds, which contains the same | |
EP0582863A3 (de) | Verfahren zur Herstellung von Isocyansäure durch Zersetzen von N,N-disubstituirten Harnstoffen. | |
IT1257001B (it) | Processo per la cristalizzazione dello iopamidolo | |
TH13050EX (th) | สารประกอบทางเภสัช | |
KR940005660A (ko) | 핵산용액의 제조방법 | |
TH26868A (da) |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
NAV | Patent application has lapsed |
Ref document number: 9402595-4 |