DE69423179D1 - Prozess zur Herstellung von optisch aktiven 2-Amino-1-phenylethanol Derivaten - Google Patents

Prozess zur Herstellung von optisch aktiven 2-Amino-1-phenylethanol Derivaten

Info

Publication number
DE69423179D1
DE69423179D1 DE69423179T DE69423179T DE69423179D1 DE 69423179 D1 DE69423179 D1 DE 69423179D1 DE 69423179 T DE69423179 T DE 69423179T DE 69423179 T DE69423179 T DE 69423179T DE 69423179 D1 DE69423179 D1 DE 69423179D1
Authority
DE
Germany
Prior art keywords
amino
production
optically active
phenylethanol derivatives
phenylethanol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69423179T
Other languages
English (en)
Other versions
DE69423179T2 (de
Inventor
Kazuaki Furukawa
Takayuki Abe
Hidekazu Akamatsu
Akinobu Matsuyama
Michio Ito
Noritsugu Yamasaki
Katsuya Miki
Kiyoshi Ikura
Takeshi Ishiguro
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Daicel Corp
Original Assignee
Daicel Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daicel Chemical Industries Ltd filed Critical Daicel Chemical Industries Ltd
Publication of DE69423179D1 publication Critical patent/DE69423179D1/de
Application granted granted Critical
Publication of DE69423179T2 publication Critical patent/DE69423179T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/22—Preparation of oxygen-containing organic compounds containing a hydroxy group aromatic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/04—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reaction of ammonia or amines with olefin oxides or halohydrins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/08—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions not involving the formation of amino groups, hydroxy groups or etherified or esterified hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/10—Separation; Purification; Stabilisation; Use of additives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/16—Preparation of optical isomers
    • C07C231/18—Preparation of optical isomers by stereospecific synthesis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/001—Amines; Imines
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/008—Preparation of nitrogen-containing organic compounds containing a N-O bond, e.g. nitro (-NO2), nitroso (-NO)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/001—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by metabolizing one of the enantiomers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/002—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by oxidation/reduction reactions
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/911—Microorganisms using fungi

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DE69423179T 1993-11-18 1994-11-18 Prozess zur Herstellung von optisch aktiven 2-Amino-1-phenylethanol Derivaten Expired - Fee Related DE69423179T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JP28941993 1993-11-18
JP31904693 1993-11-24
JP4017294 1994-03-10
JP8301494 1994-04-21
JP18321794 1994-08-04

Publications (2)

Publication Number Publication Date
DE69423179D1 true DE69423179D1 (de) 2000-04-06
DE69423179T2 DE69423179T2 (de) 2000-08-24

Family

ID=27522075

Family Applications (4)

Application Number Title Priority Date Filing Date
DE69431373T Expired - Fee Related DE69431373T2 (de) 1993-11-18 1994-11-18 Verfahren zur Herstellung von optisch aktiven 2-Amino-1-Phenylethanol-Derivaten
DE69432679T Expired - Fee Related DE69432679T2 (de) 1993-11-18 1994-11-18 Verfahren zur Herstellung von optisch aktiven 2-Amino-1-phenylethanol Derivaten
DE69423179T Expired - Fee Related DE69423179T2 (de) 1993-11-18 1994-11-18 Prozess zur Herstellung von optisch aktiven 2-Amino-1-phenylethanol Derivaten
DE69432158T Expired - Fee Related DE69432158T2 (de) 1993-11-18 1994-11-18 Verfahren zur Herstellung von optisch aktiven 2-Amino-1-phenylethanol Derivaten

Family Applications Before (2)

Application Number Title Priority Date Filing Date
DE69431373T Expired - Fee Related DE69431373T2 (de) 1993-11-18 1994-11-18 Verfahren zur Herstellung von optisch aktiven 2-Amino-1-Phenylethanol-Derivaten
DE69432679T Expired - Fee Related DE69432679T2 (de) 1993-11-18 1994-11-18 Verfahren zur Herstellung von optisch aktiven 2-Amino-1-phenylethanol Derivaten

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE69432158T Expired - Fee Related DE69432158T2 (de) 1993-11-18 1994-11-18 Verfahren zur Herstellung von optisch aktiven 2-Amino-1-phenylethanol Derivaten

Country Status (3)

Country Link
US (5) US5629200A (de)
EP (4) EP0939134B1 (de)
DE (4) DE69431373T2 (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH10165194A (ja) * 1996-12-12 1998-06-23 Sumitomo Chem Co Ltd 光学純度の向上方法
KR100717742B1 (ko) * 1999-07-21 2007-05-11 가부시키가이샤 야쿠루트 혼샤 콜레스테롤 저하제，2차 담즙산 생산 억제제 및 음식품
TWI245801B (en) * 2000-03-28 2005-12-21 Daiichi Fine Chem Co Ltd Preparation of optically active beta-aminoalcohols
KR100629642B1 (ko) 2001-03-02 2006-09-29 다이이치 파인 케미칼 가부시키가이샤 비대칭 아미노케톤 리덕타제 및 이의 핵산
KR100423875B1 (ko) * 2001-12-06 2004-03-22 주식회사 포스코 키랄 아민의 제조 방법
AU2003264502A1 (en) * 2002-09-19 2004-04-08 Kaneka Corporation Novel carbonyl reductase, gene thereof and method of using the same
WO2004028451A2 (en) * 2002-09-24 2004-04-08 Virginia Commonwealth University β-HYDROXYPHENYLALKYLAMINES AND THEIR USE FOR TREATING GLAUCOMA
DE10248277A1 (de) * 2002-10-16 2004-05-06 X-Zyme Gmbh Verfahren zur Herstellung optisch aktiver Verbindungen
JP4213524B2 (ja) * 2003-04-17 2009-01-21 ダイセル化学工業株式会社 新規なカルボニル還元酵素、その酵素をコードするｄｎａを含むポリヌクレオチド、その製造方法、およびこれを利用した光学活性アルコールの製造方法
US7268147B2 (en) 2003-05-15 2007-09-11 Pfizer Inc Compounds useful for the treatment of diseases
EP1477167A1 (de) * 2003-05-15 2004-11-17 Pfizer Limited [(2-hydroxy-2-(4-hydroxy-3-hydroxymethylphenyl)-ethylamino)-propyl] phenyl derivative als beta2 agonist
US7629358B2 (en) 2004-03-17 2009-12-08 Pfizer Inc Compounds useful for the treatment of diseases
US7538141B2 (en) 2004-03-23 2009-05-26 Alan Daniel Brown Compounds for the treatment of diseases
WO2008088830A2 (en) * 2007-01-16 2008-07-24 Evolved Nanomaterial Sciences, Inc. Chiral separating agents with active support
GB0716778D0 (en) 2007-08-29 2007-10-10 Bioeos Ltd Use
US8841486B2 (en) * 2009-10-30 2014-09-23 Aton Pharma Stereoselective synthesis of metyrosine
CN110144301B (zh) * 2018-02-10 2022-04-01 河南农业大学 一种绿针假单胞菌及其培养方法与应用
EP3781561B1 (de) 2018-04-18 2024-03-13 Constellation Pharmaceuticals, Inc. Modulatoren von methylmodifizierenden enzymen, zusammensetzungen und verwendungen davon
US11919912B2 (en) 2018-05-21 2024-03-05 Constellation Pharmaceuticals, Inc. Modulators of methyl modifying enzymes, compositions and uses thereof
WO2022157633A1 (en) * 2021-01-20 2022-07-28 Cadila Healthcare Limited Enantiomerically pure desglymidodrine and process for preparation thereof

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2816059A (en) * 1956-03-07 1957-12-10 Lilly Co Eli N-[beta-(o-chlorophenyl)-beta-(hydroxy)-ethyl] isopropyl amine, salts thereof, and compositions containing same
JPS464627Y1 (de) * 1966-12-28 1971-02-17
JPS5715582B2 (de) * 1973-05-31 1982-03-31
DE3161165D1 (en) * 1980-05-08 1983-11-17 Beecham Group Plc Arylethanolamine derivatives, their preparation and use in pharmaceutical compositions
EP0040915B1 (de) * 1980-05-22 1984-03-21 Beecham Group Plc Arylethanolamin-Derivate, ihre Herstellung und Verwendung in pharmazeutischen Zusammensetzungen
DE3267406D1 (en) * 1981-07-11 1985-12-19 Beecham Group Plc Secondary phenyl ethanol amines and their pharmaceutical use
EP0099707B1 (de) * 1982-07-16 1986-12-10 Beecham Group Plc 2-Aminoethyläther-Derivate, Verfahren zu ihrer Herstellung und sie enthaltende pharmazeutische Zusammensetzungen
HU203330B (en) * 1987-06-10 1991-07-29 Pfizer Process for producing oxazolidin-2-one derivatives and hypoglychemic pharmaceutical compositions containing them
JPH0285247A (ja) * 1988-09-22 1990-03-26 Kohjin Co Ltd 光学活性チオウレア誘導体
US5106867A (en) * 1990-05-04 1992-04-21 American Cyanamid Company Method of increasing lean meat in edible animals
US5061727A (en) * 1990-05-04 1991-10-29 American Cyanamid Company Substituted 5-(2-((2-aryl-2-hydroxyethyl)amino)propyl)-1,3-benzodioxoles
SE9003057D0 (sv) * 1990-09-26 1990-09-26 Astra Ab New process
JPH05339222A (ja) * 1992-06-09 1993-12-21 Idemitsu Petrochem Co Ltd アミド化合物の製造方法

Also Published As

Publication number Publication date
DE69432158T2 (de) 2003-10-16
US5811293A (en) 1998-09-22
EP0924193A1 (de) 1999-06-23
EP0924194B1 (de) 2003-05-14
US5629200A (en) 1997-05-13
US6114582A (en) 2000-09-05
EP0654534B1 (de) 2000-03-01
US20030143701A1 (en) 2003-07-31
US6528686B1 (en) 2003-03-04
EP0924194A3 (de) 1999-06-30
EP0924193B1 (de) 2003-02-19
EP0939134A1 (de) 1999-09-01
DE69423179T2 (de) 2000-08-24
EP0924194A2 (de) 1999-06-23
EP0939134B1 (de) 2002-09-11
DE69432679T2 (de) 2004-02-19
EP0654534A2 (de) 1995-05-24
DE69431373D1 (de) 2002-10-17
EP0654534A3 (de) 1995-09-13
DE69431373T2 (de) 2003-05-22
DE69432158D1 (de) 2003-03-27
DE69432679D1 (de) 2003-06-18

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Legal Events

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8339 Ceased/non-payment of the annual fee