DE69431373T2 - Verfahren zur Herstellung von optisch aktiven 2-Amino-1-Phenylethanol-Derivaten - Google Patents

Verfahren zur Herstellung von optisch aktiven 2-Amino-1-Phenylethanol-Derivaten

Info

Publication number
DE69431373T2
DE69431373T2 DE69431373T DE69431373T DE69431373T2 DE 69431373 T2 DE69431373 T2 DE 69431373T2 DE 69431373 T DE69431373 T DE 69431373T DE 69431373 T DE69431373 T DE 69431373T DE 69431373 T2 DE69431373 T2 DE 69431373T2
Authority
DE
Germany
Prior art keywords
amino
preparation
optically active
phenylethanol derivatives
phenylethanol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69431373T
Other languages
English (en)
Other versions
DE69431373D1 (de
Inventor
Kazuaki Furukawa
Takayuki Abe
Hidekazu Akamatsu
Akinobu Matsuyama
Michio Ito
Noritsugu Yamasaki
Katsuya Miki
Kiyoshi Ikura
Takeshi Ishiguro
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Daicel Corp
Original Assignee
Daicel Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daicel Chemical Industries Ltd filed Critical Daicel Chemical Industries Ltd
Publication of DE69431373D1 publication Critical patent/DE69431373D1/de
Application granted granted Critical
Publication of DE69431373T2 publication Critical patent/DE69431373T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/02—Preparation of oxygen-containing organic compounds containing a hydroxy group
    • C12P7/22—Preparation of oxygen-containing organic compounds containing a hydroxy group aromatic
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/04—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reaction of ammonia or amines with olefin oxides or halohydrins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/08—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton by reactions not involving the formation of amino groups, hydroxy groups or etherified or esterified hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C213/00—Preparation of compounds containing amino and hydroxy, amino and etherified hydroxy or amino and esterified hydroxy groups bound to the same carbon skeleton
    • C07C213/10—Separation; Purification; Stabilisation; Use of additives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/16—Preparation of optical isomers
    • C07C231/18—Preparation of optical isomers by stereospecific synthesis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/001—Amines; Imines
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/008—Preparation of nitrogen-containing organic compounds containing a N-O bond, e.g. nitro (-NO2), nitroso (-NO)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/001—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by metabolizing one of the enantiomers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
    • C12P41/002—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture by oxidation/reduction reactions
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/911—Microorganisms using fungi

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Analytical Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DE69431373T 1993-11-18 1994-11-18 Verfahren zur Herstellung von optisch aktiven 2-Amino-1-Phenylethanol-Derivaten Expired - Fee Related DE69431373T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
JP28941993 1993-11-18
JP31904693 1993-11-24
JP4017294 1994-03-10
JP8301494 1994-04-21
JP18321794 1994-08-04

Publications (2)

Publication Number Publication Date
DE69431373D1 DE69431373D1 (de) 2002-10-17
DE69431373T2 true DE69431373T2 (de) 2003-05-22

Family

ID=27522075

Family Applications (4)

Application Number Title Priority Date Filing Date
DE69423179T Expired - Fee Related DE69423179T2 (de) 1993-11-18 1994-11-18 Prozess zur Herstellung von optisch aktiven 2-Amino-1-phenylethanol Derivaten
DE69432158T Expired - Fee Related DE69432158T2 (de) 1993-11-18 1994-11-18 Verfahren zur Herstellung von optisch aktiven 2-Amino-1-phenylethanol Derivaten
DE69432679T Expired - Fee Related DE69432679T2 (de) 1993-11-18 1994-11-18 Verfahren zur Herstellung von optisch aktiven 2-Amino-1-phenylethanol Derivaten
DE69431373T Expired - Fee Related DE69431373T2 (de) 1993-11-18 1994-11-18 Verfahren zur Herstellung von optisch aktiven 2-Amino-1-Phenylethanol-Derivaten

Family Applications Before (3)

Application Number Title Priority Date Filing Date
DE69423179T Expired - Fee Related DE69423179T2 (de) 1993-11-18 1994-11-18 Prozess zur Herstellung von optisch aktiven 2-Amino-1-phenylethanol Derivaten
DE69432158T Expired - Fee Related DE69432158T2 (de) 1993-11-18 1994-11-18 Verfahren zur Herstellung von optisch aktiven 2-Amino-1-phenylethanol Derivaten
DE69432679T Expired - Fee Related DE69432679T2 (de) 1993-11-18 1994-11-18 Verfahren zur Herstellung von optisch aktiven 2-Amino-1-phenylethanol Derivaten

Country Status (3)

Country Link
US (5) US5629200A (de)
EP (4) EP0924194B1 (de)
DE (4) DE69423179T2 (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH10165194A (ja) * 1996-12-12 1998-06-23 Sumitomo Chem Co Ltd 光学純度の向上方法
US7101544B1 (en) * 1999-07-21 2006-09-05 Kabushiki Kaisha Yakult Honsha Cholesterol-lowering agents, secondary bile acid production inhibitors, and foods and drinks
DE60128461T2 (de) 2000-03-28 2007-09-13 Daiichi Fine Chemical Co., Ltd., Takaoka Verfahren zur herstellung von optisch aktiven beta-amino alkoholen
CN100445386C (zh) * 2001-03-02 2008-12-24 第一精密化学股份有限公司 氨基酮不对称还原酶及其核酸
KR100423875B1 (ko) * 2001-12-06 2004-03-22 주식회사 포스코 키랄 아민의 제조 방법
AU2003264502A1 (en) 2002-09-19 2004-04-08 Kaneka Corporation Novel carbonyl reductase, gene thereof and method of using the same
EP1558238A4 (de) * 2002-09-24 2006-08-30 Univ Virginia Commonwealth Beta-hydroxyphenylaldylamine und ihre verwendung zur behandlung von glaukom
DE10248277A1 (de) * 2002-10-16 2004-05-06 X-Zyme Gmbh Verfahren zur Herstellung optisch aktiver Verbindungen
JP4213524B2 (ja) * 2003-04-17 2009-01-21 ダイセル化学工業株式会社 新規なカルボニル還元酵素、その酵素をコードするｄｎａを含むポリヌクレオチド、その製造方法、およびこれを利用した光学活性アルコールの製造方法
US7268147B2 (en) 2003-05-15 2007-09-11 Pfizer Inc Compounds useful for the treatment of diseases
EP1477167A1 (de) * 2003-05-15 2004-11-17 Pfizer Limited [(2-hydroxy-2-(4-hydroxy-3-hydroxymethylphenyl)-ethylamino)-propyl] phenyl derivative als beta2 agonist
US7629358B2 (en) 2004-03-17 2009-12-08 Pfizer Inc Compounds useful for the treatment of diseases
US7538141B2 (en) 2004-03-23 2009-05-26 Alan Daniel Brown Compounds for the treatment of diseases
WO2008088830A2 (en) * 2007-01-16 2008-07-24 Evolved Nanomaterial Sciences, Inc. Chiral separating agents with active support
GB0716778D0 (en) 2007-08-29 2007-10-10 Bioeos Ltd Use
WO2011053835A1 (en) 2009-10-30 2011-05-05 Aton Pharma, Inc. Stereoselective synthesis of metyrosine
CN110144301B (zh) * 2018-02-10 2022-04-01 河南农业大学 一种绿针假单胞菌及其培养方法与应用
MA52288A (fr) 2018-04-18 2021-04-07 Constellation Pharmaceuticals Inc Modulateurs d'enzymes de modification de méthyle, compositions et utilisations de ceux-ci
CN112262143A (zh) 2018-05-21 2021-01-22 星座制药公司 甲基修饰酶的调节剂、其组合物和用途
WO2022157633A1 (en) * 2021-01-20 2022-07-28 Cadila Healthcare Limited Enantiomerically pure desglymidodrine and process for preparation thereof

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2816059A (en) * 1956-03-07 1957-12-10 Lilly Co Eli N-[beta-(o-chlorophenyl)-beta-(hydroxy)-ethyl] isopropyl amine, salts thereof, and compositions containing same
JPS464627Y1 (de) * 1966-12-28 1971-02-17
JPS5715582B2 (de) * 1973-05-31 1982-03-31
EP0040000B1 (de) * 1980-05-08 1983-10-12 Beecham Group Plc Arylethanolamin-Derivate, ihre Herstellung und Verwendung in pharmazeutischen Zusammensetzungen
DE3162756D1 (en) * 1980-05-22 1984-04-26 Beecham Group Plc Arylethanolamine derivatives, their preparation and use in pharmaceutical compositions
DE3267406D1 (en) * 1981-07-11 1985-12-19 Beecham Group Plc Secondary phenyl ethanol amines and their pharmaceutical use
DE3368258D1 (en) * 1982-07-16 1987-01-22 Beecham Group Plc 2-aminoethyl ether derivatives, processes for their preparation and pharmaceutical compositions containing them
WO1988009661A1 (en) * 1987-06-10 1988-12-15 Pfizer Inc. Oxazolidin-2-one derivatives as hypoglycemic agents
JPH0285247A (ja) * 1988-09-22 1990-03-26 Kohjin Co Ltd 光学活性チオウレア誘導体
US5106867A (en) * 1990-05-04 1992-04-21 American Cyanamid Company Method of increasing lean meat in edible animals
US5061727A (en) * 1990-05-04 1991-10-29 American Cyanamid Company Substituted 5-(2-((2-aryl-2-hydroxyethyl)amino)propyl)-1,3-benzodioxoles
SE9003057D0 (sv) * 1990-09-26 1990-09-26 Astra Ab New process
JPH05339222A (ja) * 1992-06-09 1993-12-21 Idemitsu Petrochem Co Ltd アミド化合物の製造方法

Also Published As

Publication number Publication date
EP0654534A2 (de) 1995-05-24
DE69431373D1 (de) 2002-10-17
US5811293A (en) 1998-09-22
EP0924194A3 (de) 1999-06-30
EP0939134A1 (de) 1999-09-01
EP0924193B1 (de) 2003-02-19
DE69423179T2 (de) 2000-08-24
EP0924194A2 (de) 1999-06-23
DE69432679D1 (de) 2003-06-18
US6114582A (en) 2000-09-05
DE69432158D1 (de) 2003-03-27
DE69423179D1 (de) 2000-04-06
US5629200A (en) 1997-05-13
EP0924193A1 (de) 1999-06-23
US6528686B1 (en) 2003-03-04
EP0654534B1 (de) 2000-03-01
DE69432679T2 (de) 2004-02-19
DE69432158T2 (de) 2003-10-16
US20030143701A1 (en) 2003-07-31
EP0924194B1 (de) 2003-05-14
EP0939134B1 (de) 2002-09-11
EP0654534A3 (de) 1995-09-13

Similar Documents

Publication Publication Date Title
DE69635874D1 (de) Verfahren zur Herstellung von optisch aktiven Alkoholen
DE69432158D1 (de) Verfahren zur Herstellung von optisch aktiven 2-Amino-1-phenylethanol Derivaten
DE69528008T2 (de) Verfahren zur Herstellung von optisch-aktiven 4-Hydroxy-2-Ketoglutarsäuren
DE69123025D1 (de) Verfahren zur Herstellung von optisch aktiven Gamma-butyrolactonderivaten
DE59309150D1 (de) Verfahren zur Herstellung von E,Z-Butendial-bis-dialkylacetalen
DE69432576D1 (de) Verfahren zur Herstellung von optischaktiven Epoxiden
DE69321304T2 (de) Verfahren zur Herstellung von optisch aktivem 4-Methyl-2-oxetanon
DE59401576D1 (de) Verfahren zur Herstellung von 5-Brom-6-methoxy-1-naphthoesäuremethylester
DE59407416D1 (de) Verfahren zur Herstellung von N-Alkenylpyrrolidonen
DE69623428T2 (de) Verfahren zur Herstellung von optisch aktiven Benzhydrolverbindungen
DE59401525D1 (de) Verfahren zur Herstellung von Acetoacetarylamiden
DE59401893D1 (de) Verfahren zur Herstellung von Trifluormethylanilinen
DE69306099D1 (de) Verfahren zur Herstellung von Monoalkenylbenzolen
DE69410222D1 (de) Verfahren zur Herstellung von optisch aktiven Erythro-3-amino-1,2-epoxy-Verbindungen
DE59402596D1 (de) Verfahren zur Herstellung von 5-Acetoacetylaminobenzimidazolon-2
DE69700477T2 (de) Verfahren zur Herstellung von optisch aktivem 4-Hydroxy-2-Pyrrolidon
DE59403834D1 (de) Verfahren zur Herstellung von m-Chloraromaten
DE59405751D1 (de) Verfahren zur Herstellung von Aminopropionitrilen
DE69625562T2 (de) Verfahren zur Herstellung von optisch aktiven Cyclohexanolderivaten
DE59405997D1 (de) Verfahren zur Herstellung von Hydroxyalkylaminonitrobenzol-Derivaten
DE59400502D1 (de) Verfahren zur Herstellung von Acylcyclopropanen
DE59407426D1 (de) Verfahren zur Herstellung von Fluorbenzonitrilen
DE59407425D1 (de) Verfahren zur Herstellung von Fluornitrobenzolen
DE69127219T2 (de) Verfahren zur Herstellung von optisch aktiven Alkyl-3-aryl-3-hydroxypropionaten
DE59400401D1 (de) Verfahren zur Herstellung von 2-Amino-5-aminomethyl-pyridin

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee