ATE187437T1 - Verfahren zur kristallisierung aus wasser von (s)-n,n'-bis(2-hydroxy-1-(hydroxymethiel)ethyl> 5-((2-hydroxy-1-oxopropyl)amino>-2,4,6-triiodo- ,3- benzoldicarboxamide - Google Patents

Verfahren zur kristallisierung aus wasser von (s)-n,n'-bis(2-hydroxy-1-(hydroxymethiel)ethyl> 5-((2-hydroxy-1-oxopropyl)amino>-2,4,6-triiodo- ,3- benzoldicarboxamide

Info

Publication number
ATE187437T1
ATE187437T1 AT96928403T AT96928403T ATE187437T1 AT E187437 T1 ATE187437 T1 AT E187437T1 AT 96928403 T AT96928403 T AT 96928403T AT 96928403 T AT96928403 T AT 96928403T AT E187437 T1 ATE187437 T1 AT E187437T1
Authority
AT
Austria
Prior art keywords
hydroxy
triiodo
oxopropyl
crystallization
bis
Prior art date
Application number
AT96928403T
Other languages
English (en)
Inventor
Marina Mauro
Original Assignee
Bracco Int Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from IT95RM000599 external-priority patent/IT1277934B1/it
Priority claimed from IT95RM000831 external-priority patent/IT1277950B1/it
Application filed by Bracco Int Bv filed Critical Bracco Int Bv
Application granted granted Critical
Publication of ATE187437T1 publication Critical patent/ATE187437T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00Preparation of carboxylic acid amides
    • C07C231/22Separation; Purification; Stabilisation; Use of additives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
    • A61K49/04X-ray contrast preparations

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
AT96928403T 1995-09-08 1996-08-02 Verfahren zur kristallisierung aus wasser von (s)-n,n'-bis(2-hydroxy-1-(hydroxymethiel)ethyl> 5-((2-hydroxy-1-oxopropyl)amino>-2,4,6-triiodo- ,3- benzoldicarboxamide ATE187437T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT95RM000599 IT1277934B1 (it) 1995-09-08 1995-09-08 Processo per la cristallizzazione da acqua della s-n,n' -bis- ( 2-idrossi -1 -(idrossimetil) etil) -5- ((2 -idrossi -1- ossopropil)
IT95RM000831 IT1277950B1 (it) 1995-12-19 1995-12-19 Processo per la cristallizzazione da acqua della s-n,n'-bis (2-idrossi -1-(idrossimetil)etil)-5-((2-idrossi-1-ossopropil)ammino).2,4,6-

Publications (1)

Publication Number Publication Date
ATE187437T1 true ATE187437T1 (de) 1999-12-15

Family

ID=26332086

Family Applications (1)

Application Number Title Priority Date Filing Date
AT96928403T ATE187437T1 (de) 1995-09-08 1996-08-02 Verfahren zur kristallisierung aus wasser von (s)-n,n'-bis(2-hydroxy-1-(hydroxymethiel)ethyl> 5-((2-hydroxy-1-oxopropyl)amino>-2,4,6-triiodo- ,3- benzoldicarboxamide

Country Status (17)

Country Link
US (1) US5689002A (de)
EP (1) EP0790979B1 (de)
JP (1) JP4070235B2 (de)
KR (1) KR100270411B1 (de)
CN (1) CN1070843C (de)
AT (1) ATE187437T1 (de)
AU (1) AU708195B2 (de)
BR (1) BR9606624A (de)
CA (1) CA2204734C (de)
CZ (1) CZ288645B6 (de)
DE (1) DE69605528T2 (de)
ES (1) ES2140887T3 (de)
HK (1) HK1001861A1 (de)
HU (1) HU220965B1 (de)
NO (1) NO308841B1 (de)
PL (1) PL184937B1 (de)
WO (1) WO1997009300A1 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT101720A (pt) * 1995-06-08 1997-01-31 Hovione Sociedade Quimica S A Processo para a purificacao e cristalizacao de iopamidol
KR20000031642A (ko) * 1998-11-09 2000-06-05 강재헌 이오파미돌의 결정화 방법
EA200400682A1 (ru) * 2001-11-16 2004-10-28 Рэнбакси Лабораториз Лимитед Способ получения кристаллического имипенема
CN100418945C (zh) * 2006-01-13 2008-09-17 江苏省原子医学研究所 一种碘昔兰的纯化方法
US20110021834A1 (en) * 2009-07-21 2011-01-27 Ge Healthcare As Continuous process of preparing intermediate for non-ionic x-ray contrast agents
WO2012136813A2 (en) 2011-04-07 2012-10-11 Universitetet I Oslo Agents for medical radar diagnosis
CN110023279B (zh) 2016-12-05 2022-03-11 伯拉考成像股份公司 放射照相剂中间体的机械化学合成

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH608189A5 (de) * 1974-12-13 1978-12-29 Savac Ag
IL110391A (en) * 1993-07-30 1998-12-06 Zambon Spa Process for the formation of infamidol

Also Published As

Publication number Publication date
MX9703341A (es) 1997-07-31
ES2140887T3 (es) 2000-03-01
EP0790979A1 (de) 1997-08-27
CA2204734C (en) 2009-12-29
KR100270411B1 (ko) 2000-11-01
DE69605528T2 (de) 2000-05-04
CZ288645B6 (cs) 2001-08-15
HK1001861A1 (en) 1998-07-17
NO971863L (no) 1997-04-23
BR9606624A (pt) 1997-11-11
CZ138597A3 (cs) 1998-02-18
JPH10508878A (ja) 1998-09-02
PL320027A1 (en) 1997-09-01
AU6788896A (en) 1997-03-27
NO971863D0 (no) 1997-04-23
WO1997009300A1 (en) 1997-03-13
HU220965B1 (hu) 2002-07-29
EP0790979B1 (de) 1999-12-08
HUP9801837A2 (hu) 1998-12-28
CN1070843C (zh) 2001-09-12
AU708195B2 (en) 1999-07-29
KR970707073A (ko) 1997-12-01
CA2204734A1 (en) 1997-03-13
DE69605528D1 (de) 2000-01-13
JP4070235B2 (ja) 2008-04-02
US5689002A (en) 1997-11-18
HUP9801837A3 (en) 2001-06-28
NO308841B1 (no) 2000-11-06
PL184937B1 (pl) 2003-01-31
CN1164853A (zh) 1997-11-12

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