BR9606624A - Processo para a cristalização de (s)-n,n'-bisÚ2-hidróxi-1-(hidroximetil)etil¾-5-Ú(2-hidróxi-1-oxopropil)amino¾-2,4,6-triiodo-1,3-benzonodicar-boxamida a partir de água - Google Patents

Processo para a cristalização de (s)-n,n'-bisÚ2-hidróxi-1-(hidroximetil)etil¾-5-Ú(2-hidróxi-1-oxopropil)amino¾-2,4,6-triiodo-1,3-benzonodicar-boxamida a partir de água

Info

Publication number
BR9606624A
BR9606624A BR9606624A BR9606624A BR9606624A BR 9606624 A BR9606624 A BR 9606624A BR 9606624 A BR9606624 A BR 9606624A BR 9606624 A BR9606624 A BR 9606624A BR 9606624 A BR9606624 A BR 9606624A
Authority
BR
Brazil
Prior art keywords
hydroxy
triiodo
oxopropyl
hydroxymethyl
crystallization
Prior art date
Application number
BR9606624A
Other languages
English (en)
Inventor
Marina Mauro
Original Assignee
Bracco Int Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from IT95RM000599 external-priority patent/IT1277934B1/it
Priority claimed from ITRM950831 external-priority patent/IT1277950B1/it
Application filed by Bracco Int Bv filed Critical Bracco Int Bv
Publication of BR9606624A publication Critical patent/BR9606624A/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/22—Separation; Purification; Stabilisation; Use of additives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations
BR9606624A 1995-09-08 1996-08-02 Processo para a cristalização de (s)-n,n'-bisÚ2-hidróxi-1-(hidroximetil)etil¾-5-Ú(2-hidróxi-1-oxopropil)amino¾-2,4,6-triiodo-1,3-benzonodicar-boxamida a partir de água BR9606624A (pt)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
IT95RM000599 IT1277934B1 (it) 1995-09-08 1995-09-08 Processo per la cristallizzazione da acqua della s-n,n' -bis- ( 2-idrossi -1 -(idrossimetil) etil) -5- ((2 -idrossi -1- ossopropil)
ITRM950831 IT1277950B1 (it) 1995-12-19 1995-12-19 Processo per la cristallizzazione da acqua della s-n,n'-bis (2-idrossi -1-(idrossimetil)etil)-5-((2-idrossi-1-ossopropil)ammino).2,4,6-
PCT/EP1996/003399 WO1997009300A1 (en) 1995-09-08 1996-08-02 Process for the crystallization from water of (s)-n,n'-bis[2-hydroxy-1-(hydroxymethyl)ethyl]-5-[(2-hydroxy-1-oxopropyl)amino]-2,4,6-triiodo-1,3-benzendicarboxamide

Publications (1)

Publication Number Publication Date
BR9606624A true BR9606624A (pt) 1997-11-11

Family

ID=26332086

Family Applications (1)

Application Number Title Priority Date Filing Date
BR9606624A BR9606624A (pt) 1995-09-08 1996-08-02 Processo para a cristalização de (s)-n,n'-bisÚ2-hidróxi-1-(hidroximetil)etil¾-5-Ú(2-hidróxi-1-oxopropil)amino¾-2,4,6-triiodo-1,3-benzonodicar-boxamida a partir de água

Country Status (17)

Country Link
US (1) US5689002A (pt)
EP (1) EP0790979B1 (pt)
JP (1) JP4070235B2 (pt)
KR (1) KR100270411B1 (pt)
CN (1) CN1070843C (pt)
AT (1) ATE187437T1 (pt)
AU (1) AU708195B2 (pt)
BR (1) BR9606624A (pt)
CA (1) CA2204734C (pt)
CZ (1) CZ288645B6 (pt)
DE (1) DE69605528T2 (pt)
ES (1) ES2140887T3 (pt)
HK (1) HK1001861A1 (pt)
HU (1) HU220965B1 (pt)
NO (1) NO308841B1 (pt)
PL (1) PL184937B1 (pt)
WO (1) WO1997009300A1 (pt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT101720A (pt) * 1995-06-08 1997-01-31 Hovione Sociedade Quimica S A Processo para a purificacao e cristalizacao de iopamidol
KR20000031642A (ko) * 1998-11-09 2000-06-05 강재헌 이오파미돌의 결정화 방법
MXPA04004604A (es) 2001-11-16 2004-09-10 Ranbaxy Lab Ltd Proceso para la preparacion de imipenem cristalino.
CN100418945C (zh) * 2006-01-13 2008-09-17 江苏省原子医学研究所 一种碘昔兰的纯化方法
US20110021834A1 (en) * 2009-07-21 2011-01-27 Ge Healthcare As Continuous process of preparing intermediate for non-ionic x-ray contrast agents
WO2012136813A2 (en) 2011-04-07 2012-10-11 Universitetet I Oslo Agents for medical radar diagnosis
WO2018104228A1 (en) 2016-12-05 2018-06-14 Bracco Imaging Spa Mechanochemical synthesis of radiographic agents intermediates

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH608189A5 (pt) * 1974-12-13 1978-12-29 Savac Ag
IL110391A (en) * 1993-07-30 1998-12-06 Zambon Spa Process for the formation of infamidol

Also Published As

Publication number Publication date
HK1001861A1 (en) 1998-07-17
HU220965B1 (hu) 2002-07-29
CN1070843C (zh) 2001-09-12
US5689002A (en) 1997-11-18
NO971863D0 (no) 1997-04-23
JPH10508878A (ja) 1998-09-02
JP4070235B2 (ja) 2008-04-02
KR100270411B1 (ko) 2000-11-01
MX9703341A (es) 1997-07-31
AU708195B2 (en) 1999-07-29
WO1997009300A1 (en) 1997-03-13
PL320027A1 (en) 1997-09-01
KR970707073A (ko) 1997-12-01
HUP9801837A2 (hu) 1998-12-28
NO971863L (no) 1997-04-23
CA2204734A1 (en) 1997-03-13
DE69605528D1 (de) 2000-01-13
CN1164853A (zh) 1997-11-12
ATE187437T1 (de) 1999-12-15
DE69605528T2 (de) 2000-05-04
HUP9801837A3 (en) 2001-06-28
EP0790979B1 (en) 1999-12-08
CA2204734C (en) 2009-12-29
CZ288645B6 (cs) 2001-08-15
EP0790979A1 (en) 1997-08-27
PL184937B1 (pl) 2003-01-31
ES2140887T3 (es) 2000-03-01
AU6788896A (en) 1997-03-27
NO308841B1 (no) 2000-11-06
CZ138597A3 (cs) 1998-02-18

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Legal Events

Date Code Title Description
EG Technical examination (opinion): publication of technical examination (opinion)
B09B Patent application refused [chapter 9.2 patent gazette]
B12B Appeal against refusal [chapter 12.2 patent gazette]