NO308841B1 - FremgangsmÕte ved krystallisasjon av (S)-N,N'-bis[2-hydroksy- 1-(hydroksymetyl)etyl]-5[(2-hydroksy-1-oksopropyl)amino]-2,4,6- trijod-1,3-benzendikarboksamid fra vann, samt anvendelser av (C1- C4-alkoholer - Google Patents

FremgangsmÕte ved krystallisasjon av (S)-N,N'-bis[2-hydroksy- 1-(hydroksymetyl)etyl]-5[(2-hydroksy-1-oksopropyl)amino]-2,4,6- trijod-1,3-benzendikarboksamid fra vann, samt anvendelser av (C1- C4-alkoholer

Info

Publication number
NO308841B1
NO308841B1 NO971863A NO971863A NO308841B1 NO 308841 B1 NO308841 B1 NO 308841B1 NO 971863 A NO971863 A NO 971863A NO 971863 A NO971863 A NO 971863A NO 308841 B1 NO308841 B1 NO 308841B1
Authority
NO
Norway
Prior art keywords
hydroxy
triiodo
oxopropyl
hydroxymethyl
crystallization
Prior art date
Application number
NO971863A
Other languages
English (en)
Norwegian (no)
Other versions
NO971863L (no
NO971863D0 (no
Inventor
Marina Mauro
Original Assignee
Bracco Int Bv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from ITRM950599 external-priority patent/IT1277934B1/it
Priority claimed from IT95RM000831 external-priority patent/IT1277950B1/it
Application filed by Bracco Int Bv filed Critical Bracco Int Bv
Publication of NO971863L publication Critical patent/NO971863L/no
Publication of NO971863D0 publication Critical patent/NO971863D0/no
Publication of NO308841B1 publication Critical patent/NO308841B1/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00—Preparation of carboxylic acid amides
    • C07C231/22—Separation; Purification; Stabilisation; Use of additives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/04—X-ray contrast preparations
NO971863A 1995-09-08 1997-04-23 FremgangsmÕte ved krystallisasjon av (S)-N,N'-bis[2-hydroksy- 1-(hydroksymetyl)etyl]-5[(2-hydroksy-1-oksopropyl)amino]-2,4,6- trijod-1,3-benzendikarboksamid fra vann, samt anvendelser av (C1- C4-alkoholer NO308841B1 (no)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ITRM950599 IT1277934B1 (it) 1995-09-08 1995-09-08 Processo per la cristallizzazione da acqua della s-n,n' -bis- ( 2-idrossi -1 -(idrossimetil) etil) -5- ((2 -idrossi -1- ossopropil)
IT95RM000831 IT1277950B1 (it) 1995-12-19 1995-12-19 Processo per la cristallizzazione da acqua della s-n,n'-bis (2-idrossi -1-(idrossimetil)etil)-5-((2-idrossi-1-ossopropil)ammino).2,4,6-
PCT/EP1996/003399 WO1997009300A1 (en) 1995-09-08 1996-08-02 Process for the crystallization from water of (s)-n,n'-bis[2-hydroxy-1-(hydroxymethyl)ethyl]-5-[(2-hydroxy-1-oxopropyl)amino]-2,4,6-triiodo-1,3-benzendicarboxamide

Publications (3)

Publication Number Publication Date
NO971863L NO971863L (no) 1997-04-23
NO971863D0 NO971863D0 (no) 1997-04-23
NO308841B1 true NO308841B1 (no) 2000-11-06

Family

ID=26332086

Family Applications (1)

Application Number Title Priority Date Filing Date
NO971863A NO308841B1 (no) 1995-09-08 1997-04-23 FremgangsmÕte ved krystallisasjon av (S)-N,N'-bis[2-hydroksy- 1-(hydroksymetyl)etyl]-5[(2-hydroksy-1-oksopropyl)amino]-2,4,6- trijod-1,3-benzendikarboksamid fra vann, samt anvendelser av (C1- C4-alkoholer

Country Status (17)

Country Link
US (1) US5689002A (pt)
EP (1) EP0790979B1 (pt)
JP (1) JP4070235B2 (pt)
KR (1) KR100270411B1 (pt)
CN (1) CN1070843C (pt)
AT (1) ATE187437T1 (pt)
AU (1) AU708195B2 (pt)
BR (1) BR9606624A (pt)
CA (1) CA2204734C (pt)
CZ (1) CZ288645B6 (pt)
DE (1) DE69605528T2 (pt)
ES (1) ES2140887T3 (pt)
HK (1) HK1001861A1 (pt)
HU (1) HU220965B1 (pt)
NO (1) NO308841B1 (pt)
PL (1) PL184937B1 (pt)
WO (1) WO1997009300A1 (pt)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT101720A (pt) * 1995-06-08 1997-01-31 Hovione Sociedade Quimica S A Processo para a purificacao e cristalizacao de iopamidol
KR20000031642A (ko) * 1998-11-09 2000-06-05 강재헌 이오파미돌의 결정화 방법
WO2003042215A1 (en) 2001-11-16 2003-05-22 Ranbaxy Laboratories Limited Process for the preparation of crystalline imipenem
CN100418945C (zh) * 2006-01-13 2008-09-17 江苏省原子医学研究所 一种碘昔兰的纯化方法
US20110021834A1 (en) * 2009-07-21 2011-01-27 Ge Healthcare As Continuous process of preparing intermediate for non-ionic x-ray contrast agents
WO2012136813A2 (en) 2011-04-07 2012-10-11 Universitetet I Oslo Agents for medical radar diagnosis
EP3548461B1 (en) 2016-12-05 2021-02-03 Bracco Imaging SpA Mechanochemical synthesis of radiographic agents intermediates

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH608189A5 (pt) * 1974-12-13 1978-12-29 Savac Ag
IL110391A (en) * 1993-07-30 1998-12-06 Zambon Spa Process for the formation of infamidol

Also Published As

Publication number Publication date
AU6788896A (en) 1997-03-27
CA2204734A1 (en) 1997-03-13
HU220965B1 (hu) 2002-07-29
HUP9801837A3 (en) 2001-06-28
ES2140887T3 (es) 2000-03-01
KR100270411B1 (ko) 2000-11-01
DE69605528D1 (de) 2000-01-13
CZ138597A3 (cs) 1998-02-18
DE69605528T2 (de) 2000-05-04
AU708195B2 (en) 1999-07-29
PL184937B1 (pl) 2003-01-31
JPH10508878A (ja) 1998-09-02
HUP9801837A2 (hu) 1998-12-28
EP0790979B1 (en) 1999-12-08
WO1997009300A1 (en) 1997-03-13
NO971863L (no) 1997-04-23
PL320027A1 (en) 1997-09-01
ATE187437T1 (de) 1999-12-15
MX9703341A (es) 1997-07-31
JP4070235B2 (ja) 2008-04-02
CN1070843C (zh) 2001-09-12
US5689002A (en) 1997-11-18
NO971863D0 (no) 1997-04-23
CA2204734C (en) 2009-12-29
BR9606624A (pt) 1997-11-11
CZ288645B6 (cs) 2001-08-15
CN1164853A (zh) 1997-11-12
KR970707073A (ko) 1997-12-01
HK1001861A1 (en) 1998-07-17
EP0790979A1 (en) 1997-08-27

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