IT1257001B - Processo per la cristalizzazione dello iopamidolo - Google Patents
Processo per la cristalizzazione dello iopamidoloInfo
- Publication number
- IT1257001B IT1257001B ITMI931720A ITMI931720A IT1257001B IT 1257001 B IT1257001 B IT 1257001B IT MI931720 A ITMI931720 A IT MI931720A IT MI931720 A ITMI931720 A IT MI931720A IT 1257001 B IT1257001 B IT 1257001B
- Authority
- IT
- Italy
- Prior art keywords
- iopamidol
- crystallisation
- butanol
- pharmacopoeia
- sec
- Prior art date
Links
- XQZXYNRDCRIARQ-LURJTMIESA-N iopamidol Chemical compound C[C@H](O)C(=O)NC1=C(I)C(C(=O)NC(CO)CO)=C(I)C(C(=O)NC(CO)CO)=C1I XQZXYNRDCRIARQ-LURJTMIESA-N 0.000 title abstract 3
- 229960004647 iopamidol Drugs 0.000 title abstract 3
- 238000002425 crystallisation Methods 0.000 title abstract 2
- 238000000034 method Methods 0.000 title abstract 2
- LRHPLDYGYMQRHN-UHFFFAOYSA-N N-Butanol Chemical compound CCCCO LRHPLDYGYMQRHN-UHFFFAOYSA-N 0.000 abstract 2
- BTANRVKWQNVYAZ-UHFFFAOYSA-N butan-2-ol Chemical compound CCC(C)O BTANRVKWQNVYAZ-UHFFFAOYSA-N 0.000 abstract 2
- 239000007864 aqueous solution Substances 0.000 abstract 1
- 239000002904 solvent Substances 0.000 abstract 1
Abstract
Viene descritto un processo per la cristallizzazione dello Iopamidolo che impiega n.butanolo o sec.butanolo come solvente. Lo Iopamidolo viene ottenuto con alte rese, anche partendo da soluzioni acquose dello stesso e possiede caratteristiche in accordo a quelle richieste dalla farmacopea.
Priority Applications (32)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITMI931720A IT1257001B (it) | 1993-07-30 | 1993-07-30 | Processo per la cristalizzazione dello iopamidolo |
IL11039194A IL110391A (en) | 1993-07-30 | 1994-07-20 | Process for the formation of infamidol |
SI9420046A SI9420046B (sl) | 1993-07-30 | 1994-07-22 | Postopek za kristalizacijo Iopamidola |
GR940100366A GR940100366A (en) | 1993-07-30 | 1994-07-22 | Process for the crystallization of iopamidol. |
RU96105070A RU2135462C1 (ru) | 1993-07-30 | 1994-07-22 | Способ кристаллизации иопамидола |
PCT/EP1994/002415 WO1995004031A1 (en) | 1993-07-30 | 1994-07-22 | Process for the crystallization of iopamidol |
HU9600191A HU217023B (hu) | 1993-07-30 | 1994-07-22 | Eljárás jopamidol kristályosítására |
AU75321/94A AU690138B2 (en) | 1993-07-30 | 1994-07-22 | Process for the crystallization of iopamidol |
NZ271632A NZ271632A (en) | 1993-07-30 | 1994-07-22 | Crystallisation of iopamidol using an isomer of butanol |
CN94192930A CN1035940C (zh) | 1993-07-30 | 1994-07-22 | 碘异酞醇的结晶方法 |
KR1019960700580A KR100355211B1 (ko) | 1993-07-30 | 1994-07-22 | 요오파미돌의결정화방법 |
ZA945472A ZA945472B (en) | 1993-07-30 | 1994-07-25 | Process for the crystallization of iopamidol |
GB9414912A GB2280436B (en) | 1993-07-30 | 1994-07-25 | Process for the crystallization of lopamidol |
FR9409238A FR2708601B1 (fr) | 1993-07-30 | 1994-07-26 | Procédé de cristallisation d'Iopamidol. |
CH02354/94A CH686783A5 (it) | 1993-07-30 | 1994-07-26 | Processo per la cristallizzazione dello Iopamidolo. |
PT101554A PT101554B (pt) | 1993-07-30 | 1994-07-26 | Processo para a cristalizacao de iopamidol utilizando um butanol como solvente, iopamidol cristalino assim obtido e agentes de contraste radiograficos que o contem |
NL9401229A NL194272C (nl) | 1993-07-30 | 1994-07-26 | Werkwijze voor de kristallisatie van iopamidol. |
CA002128942A CA2128942C (en) | 1993-07-30 | 1994-07-27 | Process for the crystallization of iopamidol |
DE4426818A DE4426818A1 (de) | 1993-07-30 | 1994-07-28 | Verfahren zur Kristallisation von Iopamidol |
ES09401679A ES2102312B1 (es) | 1993-07-30 | 1994-07-29 | Procedimiento para la cristalizacion del iopamidol |
IE940609A IE80675B1 (en) | 1993-07-30 | 1994-07-29 | Process for the crystallization of iopamidol |
BE9400717A BE1008403A4 (fr) | 1993-07-30 | 1994-07-29 | Procede de cristallisation d'iopamidol. |
US08/281,985 US5571941A (en) | 1993-07-30 | 1994-07-29 | Process for the purifying of iopamidol |
CZ19941831A CZ289300B6 (cs) | 1993-07-30 | 1994-07-29 | Způsob krystalizace iopamidolu a neiontové kontrastní médium |
JP17811594A JP3299045B2 (ja) | 1993-07-30 | 1994-07-29 | イオパミドールを結晶化する方法 |
AT0150594A AT404832B (de) | 1993-07-30 | 1994-07-29 | Verfahren zur kristallisation von iopamidol |
SE9402595A SE9402595L (sv) | 1993-07-30 | 1994-07-29 | Förfarande för kristallisation av iopamidol |
DK089294A DK172074B1 (da) | 1993-07-30 | 1994-07-29 | Fremgangsmåde til krystallisation af iopamidol og anvendelse af butanol dertil |
FI960400A FI960400A (fi) | 1993-07-30 | 1996-01-29 | Menetelmä iopamidolin kiteyttämiseksi |
NO960376A NO304226B1 (no) | 1993-07-30 | 1996-01-29 | FremgangsmÕte for krystallisering av iopamidol, samt anvendelse av butanoler ved krystalliseringen |
US08/797,610 USRE36433E (en) | 1993-07-30 | 1997-02-07 | Process for the purifying of iopamidol |
US09/139,894 US6506938B1 (en) | 1993-07-30 | 1998-08-25 | Process for the purifying of iopamidol |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITMI931720A IT1257001B (it) | 1993-07-30 | 1993-07-30 | Processo per la cristalizzazione dello iopamidolo |
Publications (3)
Publication Number | Publication Date |
---|---|
ITMI931720A0 ITMI931720A0 (it) | 1993-07-30 |
ITMI931720A1 ITMI931720A1 (it) | 1995-01-30 |
IT1257001B true IT1257001B (it) | 1996-01-05 |
Family
ID=11366736
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ITMI931720A IT1257001B (it) | 1993-07-30 | 1993-07-30 | Processo per la cristalizzazione dello iopamidolo |
Country Status (1)
Country | Link |
---|---|
IT (1) | IT1257001B (it) |
-
1993
- 1993-07-30 IT ITMI931720A patent/IT1257001B/it active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
ITMI931720A0 (it) | 1993-07-30 |
ITMI931720A1 (it) | 1995-01-30 |
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