RU2199541C2 - Тиенопиримидины, способ их получения (варианты), фармацевтическая композиция и способ ее получения - Google Patents

Тиенопиримидины, способ их получения (варианты), фармацевтическая композиция и способ ее получения Download PDF

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Publication number
RU2199541C2
RU2199541C2 RU99104796/04A RU99104796A RU2199541C2 RU 2199541 C2 RU2199541 C2 RU 2199541C2 RU 99104796/04 A RU99104796/04 A RU 99104796/04A RU 99104796 A RU99104796 A RU 99104796A RU 2199541 C2 RU2199541 C2 RU 2199541C2
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RU
Russia
Prior art keywords
pyrimidine
chloro
pyridin
thieno
methylthieno
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RU99104796/04A
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English (en)
Russian (ru)
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RU99104796A (ru
Inventor
Йонас Рохус
Пьер ШЕЛЛИНГ
Франц-Вернер КЛУКСЕН
Мария Кристадлер
Original Assignee
Мерк Патент Гмбх
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Publication of RU99104796A publication Critical patent/RU99104796A/ru
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure

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  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Hospice & Palliative Care (AREA)
  • Gynecology & Obstetrics (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
RU99104796/04A 1996-08-12 1997-07-30 Тиенопиримидины, способ их получения (варианты), фармацевтическая композиция и способ ее получения RU2199541C2 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19632423A DE19632423A1 (de) 1996-08-12 1996-08-12 Thienopyrimidine
DE19632423.8 1996-08-12

Publications (2)

Publication Number Publication Date
RU99104796A RU99104796A (ru) 2001-01-20
RU2199541C2 true RU2199541C2 (ru) 2003-02-27

Family

ID=7802392

Family Applications (1)

Application Number Title Priority Date Filing Date
RU99104796/04A RU2199541C2 (ru) 1996-08-12 1997-07-30 Тиенопиримидины, способ их получения (варианты), фармацевтическая композиция и способ ее получения

Country Status (28)

Country Link
US (1) US6110920A (enExample)
EP (1) EP0920431B1 (enExample)
JP (1) JP4405593B2 (enExample)
KR (1) KR100502271B1 (enExample)
CN (1) CN1081638C (enExample)
AR (1) AR009052A1 (enExample)
AT (1) ATE233265T1 (enExample)
AU (1) AU725227B2 (enExample)
BR (1) BR9711062A (enExample)
CA (1) CA2263561C (enExample)
CZ (1) CZ287772B6 (enExample)
DE (2) DE19632423A1 (enExample)
DK (1) DK0920431T3 (enExample)
ES (1) ES2191192T3 (enExample)
HU (1) HUP0001607A3 (enExample)
IL (1) IL128504A (enExample)
NO (1) NO990643L (enExample)
NZ (1) NZ334600A (enExample)
PL (1) PL190174B1 (enExample)
PT (1) PT920431E (enExample)
RU (1) RU2199541C2 (enExample)
SI (1) SI0920431T1 (enExample)
SK (1) SK282823B6 (enExample)
TR (1) TR199900308T2 (enExample)
TW (1) TW359672B (enExample)
UA (1) UA55421C2 (enExample)
WO (1) WO1998006722A1 (enExample)
ZA (1) ZA977156B (enExample)

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US7276529B2 (en) 2002-03-20 2007-10-02 Celgene Corporation Methods of the treatment or prevention of exercise-induced asthma using (+)-2-[1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione
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JP7114076B2 (ja) 2015-12-22 2022-08-08 シャイ・セラピューティクス・エルエルシー がん及び炎症性疾患の処置のための化合物
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WO1995019774A1 (en) * 1994-01-25 1995-07-27 Warner-Lambert Company Bicyclic compounds capable of inhibiting tyrosine kinases of the epidermal growth factor receptor family

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US4196207A (en) * 1977-05-23 1980-04-01 Ici Australia Limited Process for controlling eradicating or preventing infestations of animals by Ixodid ticks
WO1995019774A1 (en) * 1994-01-25 1995-07-27 Warner-Lambert Company Bicyclic compounds capable of inhibiting tyrosine kinases of the epidermal growth factor receptor family

Also Published As

Publication number Publication date
NO990643D0 (no) 1999-02-11
KR100502271B1 (ko) 2005-07-22
IL128504A0 (en) 2000-01-31
WO1998006722A1 (de) 1998-02-19
JP2000516223A (ja) 2000-12-05
TR199900308T2 (xx) 1999-04-21
ZA977156B (en) 1998-02-19
CN1227560A (zh) 1999-09-01
ES2191192T3 (es) 2003-09-01
KR20000029932A (ko) 2000-05-25
CA2263561C (en) 2007-02-20
SI0920431T1 (en) 2003-08-31
HUP0001607A3 (en) 2002-09-30
US6110920A (en) 2000-08-29
DK0920431T3 (da) 2003-06-02
EP0920431B1 (de) 2003-02-26
CA2263561A1 (en) 1998-02-19
IL128504A (en) 2003-01-12
HK1021731A1 (en) 2000-06-30
SK16499A3 (en) 1999-06-11
PT920431E (pt) 2003-07-31
PL190174B1 (pl) 2005-11-30
TW359672B (en) 1999-06-01
CZ44899A3 (cs) 1999-05-12
BR9711062A (pt) 1999-08-17
NZ334600A (en) 2000-07-28
PL331538A1 (en) 1999-07-19
EP0920431A1 (de) 1999-06-09
DE59709404D1 (en) 2003-04-03
UA55421C2 (uk) 2003-04-15
CN1081638C (zh) 2002-03-27
ATE233265T1 (de) 2003-03-15
SK282823B6 (sk) 2002-12-03
JP4405593B2 (ja) 2010-01-27
AU725227B2 (en) 2000-10-12
AU4203597A (en) 1998-03-06
DE19632423A1 (de) 1998-02-19
HUP0001607A2 (hu) 2000-10-28
CZ287772B6 (en) 2001-01-17
AR009052A1 (es) 2000-03-08
NO990643L (no) 1999-02-11

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Effective date: 20060731