ATE233265T1 - Thienopyrimidine - Google Patents

Thienopyrimidine

Info

Publication number
ATE233265T1
ATE233265T1 AT97940047T AT97940047T ATE233265T1 AT E233265 T1 ATE233265 T1 AT E233265T1 AT 97940047 T AT97940047 T AT 97940047T AT 97940047 T AT97940047 T AT 97940047T AT E233265 T1 ATE233265 T1 AT E233265T1
Authority
AT
Austria
Prior art keywords
thienopyrimidines
Prior art date
Application number
AT97940047T
Other languages
German (de)
English (en)
Inventor
Jonas Rochus
Pierre Schelling
Franz-Werner Kluxen
Maria Christadler
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Application granted granted Critical
Publication of ATE233265T1 publication Critical patent/ATE233265T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Gynecology & Obstetrics (AREA)
  • Hospice & Palliative Care (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT97940047T 1996-08-12 1997-07-30 Thienopyrimidine ATE233265T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19632423A DE19632423A1 (de) 1996-08-12 1996-08-12 Thienopyrimidine
PCT/EP1997/004139 WO1998006722A1 (de) 1996-08-12 1997-07-30 Thienopyrimidine

Publications (1)

Publication Number Publication Date
ATE233265T1 true ATE233265T1 (de) 2003-03-15

Family

ID=7802392

Family Applications (1)

Application Number Title Priority Date Filing Date
AT97940047T ATE233265T1 (de) 1996-08-12 1997-07-30 Thienopyrimidine

Country Status (28)

Country Link
US (1) US6110920A (enExample)
EP (1) EP0920431B1 (enExample)
JP (1) JP4405593B2 (enExample)
KR (1) KR100502271B1 (enExample)
CN (1) CN1081638C (enExample)
AR (1) AR009052A1 (enExample)
AT (1) ATE233265T1 (enExample)
AU (1) AU725227B2 (enExample)
BR (1) BR9711062A (enExample)
CA (1) CA2263561C (enExample)
CZ (1) CZ287772B6 (enExample)
DE (2) DE19632423A1 (enExample)
DK (1) DK0920431T3 (enExample)
ES (1) ES2191192T3 (enExample)
HU (1) HUP0001607A3 (enExample)
IL (1) IL128504A (enExample)
NO (1) NO990643L (enExample)
NZ (1) NZ334600A (enExample)
PL (1) PL190174B1 (enExample)
PT (1) PT920431E (enExample)
RU (1) RU2199541C2 (enExample)
SI (1) SI0920431T1 (enExample)
SK (1) SK282823B6 (enExample)
TR (1) TR199900308T2 (enExample)
TW (1) TW359672B (enExample)
UA (1) UA55421C2 (enExample)
WO (1) WO1998006722A1 (enExample)
ZA (1) ZA977156B (enExample)

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US6339106B1 (en) 1999-08-11 2002-01-15 Sepracor, Inc. Methods and compositions for the treatment and prevention of sexual dysfunction
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US6399826B1 (en) 1999-08-11 2002-06-04 Sepracor Inc. Salts of sibutramine metabolites, methods of making sibutramine metabolites and intermediates useful in the same, and methods of treating pain
DE19950647A1 (de) * 1999-10-21 2001-04-26 Merck Patent Gmbh Imidazolderivate als Phosphodiesterase VII-Hemmer
DE10031585A1 (de) * 2000-06-29 2002-01-10 Merck Patent Gmbh 2-Aminoalkyl-thieno[2,3-d]pyrimidine
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BR0206853A (pt) * 2001-02-02 2004-01-13 Merck Patent Ges Mit Beschroen Formulação farmacêutica compreendendo pirazolo[4,3-d]pirimidinas e antagonistas de receptor de endotelina ou tienopirimidinas e antagonistas de receptor de endotelina
US6610887B2 (en) 2001-04-13 2003-08-26 Sepracor Inc. Methods of preparing didesmethylsibutramine and other sibutramine derivatives
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DE10351436A1 (de) * 2003-11-04 2005-06-09 Merck Patent Gmbh Verwendung von Thienopyrimidinen
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US8697689B2 (en) 2008-10-16 2014-04-15 Janssen Pharmaceuticals, Inc. Indole and benzomorpholine derivatives as modulators of metabotropic glutamate receptors
RU2512283C2 (ru) 2008-11-28 2014-04-10 Янссен Фармасьютикалз, Инк. Производные индола и бензоксазина в качестве модуляторов метаботропных глутаматных рецепторов
JO2907B1 (en) 2009-05-12 2015-09-15 اديكس فرما اس ايه Pyridine derivatives 1, 2, 4 trisolo [4, 3-A] and their uses as positive LLs for 2MGLUR receptors
NZ596053A (en) 2009-05-12 2013-05-31 Janssen Pharmaceuticals Inc 1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mglur2 receptors
MY153913A (en) 2009-05-12 2015-04-15 Janssen Pharmaceuticals Inc 7-aryl-1,2,4-triazolo[4,3-a]pyridine derivatives and their use as positive allosteric modulators of mglur2 receptors
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CN103298810B (zh) 2010-11-08 2016-03-16 杨森制药公司 1,2,4-三唑并[4,3-a]吡啶衍生物及其作为MGLUR2受体的正变构调节剂的用途
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US20150119399A1 (en) 2012-01-10 2015-04-30 President And Fellows Of Harvard College Beta-cell replication promoting compounds and methods of their use
ES2806606T3 (es) 2012-08-06 2021-02-18 Firmenich Incorporated Modificador del sabor dulce
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JO3367B1 (ar) 2013-09-06 2019-03-13 Janssen Pharmaceutica Nv مركبات 2،1، 4- ثلاثي زولو [3،4-a] بيريدين واستخدامها بصفة منظمات تفارغية موجبة لمستقبلات ميجلور 2
EA033889B1 (ru) 2014-01-21 2019-12-05 Янссен Фармацевтика Нв Комбинация на основе лиганда sv2a и положительного аллостерического модулятора метаботропного глутаматергического рецептора 2 подтипа
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BR112019027640A2 (pt) 2017-06-21 2020-07-07 SHY Therapeutics LLC composto, método para testar a capacidade de um ou mais compostos, método para inibir a função de ras, método para inibir a função de rho, método para inibir a função de rac, composição farmacêutica
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Also Published As

Publication number Publication date
EP0920431A1 (de) 1999-06-09
NO990643D0 (no) 1999-02-11
DK0920431T3 (da) 2003-06-02
UA55421C2 (uk) 2003-04-15
DE59709404D1 (en) 2003-04-03
AU4203597A (en) 1998-03-06
JP2000516223A (ja) 2000-12-05
BR9711062A (pt) 1999-08-17
SK16499A3 (en) 1999-06-11
CN1227560A (zh) 1999-09-01
AR009052A1 (es) 2000-03-08
CZ44899A3 (cs) 1999-05-12
IL128504A (en) 2003-01-12
CA2263561A1 (en) 1998-02-19
AU725227B2 (en) 2000-10-12
DE19632423A1 (de) 1998-02-19
TW359672B (en) 1999-06-01
CZ287772B6 (en) 2001-01-17
NZ334600A (en) 2000-07-28
TR199900308T2 (xx) 1999-04-21
SK282823B6 (sk) 2002-12-03
PT920431E (pt) 2003-07-31
US6110920A (en) 2000-08-29
ZA977156B (en) 1998-02-19
NO990643L (no) 1999-02-11
KR100502271B1 (ko) 2005-07-22
HK1021731A1 (en) 2000-06-30
PL331538A1 (en) 1999-07-19
CA2263561C (en) 2007-02-20
KR20000029932A (ko) 2000-05-25
CN1081638C (zh) 2002-03-27
HUP0001607A3 (en) 2002-09-30
RU2199541C2 (ru) 2003-02-27
IL128504A0 (en) 2000-01-31
WO1998006722A1 (de) 1998-02-19
EP0920431B1 (de) 2003-02-26
PL190174B1 (pl) 2005-11-30
HUP0001607A2 (hu) 2000-10-28
ES2191192T3 (es) 2003-09-01
JP4405593B2 (ja) 2010-01-27
SI0920431T1 (en) 2003-08-31

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