SI0920431T1 - Thienopyrimidines - Google Patents

Thienopyrimidines

Info

Publication number
SI0920431T1
SI0920431T1 SI9730518T SI9730518T SI0920431T1 SI 0920431 T1 SI0920431 T1 SI 0920431T1 SI 9730518 T SI9730518 T SI 9730518T SI 9730518 T SI9730518 T SI 9730518T SI 0920431 T1 SI0920431 T1 SI 0920431T1
Authority
SI
Slovenia
Prior art keywords
thienopyrimidines
Prior art date
Application number
SI9730518T
Other languages
English (en)
Slovenian (sl)
Inventor
Jonas Rochus
Pierre Schelling
Franz-Werner Kluxen
Maria Christadler
Original Assignee
Merck Patent Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent Gmbh filed Critical Merck Patent Gmbh
Publication of SI0920431T1 publication Critical patent/SI0920431T1/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10Drugs for genital or sexual disorders; Contraceptives for impotence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/02Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/04Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Hospice & Palliative Care (AREA)
  • Gynecology & Obstetrics (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
SI9730518T 1996-08-12 1997-07-30 Thienopyrimidines SI0920431T1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE19632423A DE19632423A1 (de) 1996-08-12 1996-08-12 Thienopyrimidine
PCT/EP1997/004139 WO1998006722A1 (de) 1996-08-12 1997-07-30 Thienopyrimidine
EP97940047A EP0920431B1 (de) 1996-08-12 1997-07-30 Thienopyrimidine

Publications (1)

Publication Number Publication Date
SI0920431T1 true SI0920431T1 (en) 2003-08-31

Family

ID=7802392

Family Applications (1)

Application Number Title Priority Date Filing Date
SI9730518T SI0920431T1 (en) 1996-08-12 1997-07-30 Thienopyrimidines

Country Status (29)

Country Link
US (1) US6110920A (xx)
EP (1) EP0920431B1 (xx)
JP (1) JP4405593B2 (xx)
KR (1) KR100502271B1 (xx)
CN (1) CN1081638C (xx)
AR (1) AR009052A1 (xx)
AT (1) ATE233265T1 (xx)
AU (1) AU725227B2 (xx)
BR (1) BR9711062A (xx)
CA (1) CA2263561C (xx)
CZ (1) CZ287772B6 (xx)
DE (2) DE19632423A1 (xx)
DK (1) DK0920431T3 (xx)
ES (1) ES2191192T3 (xx)
HK (1) HK1021731A1 (xx)
HU (1) HUP0001607A3 (xx)
IL (1) IL128504A (xx)
NO (1) NO990643L (xx)
NZ (1) NZ334600A (xx)
PL (1) PL190174B1 (xx)
PT (1) PT920431E (xx)
RU (1) RU2199541C2 (xx)
SI (1) SI0920431T1 (xx)
SK (1) SK282823B6 (xx)
TR (1) TR199900308T2 (xx)
TW (1) TW359672B (xx)
UA (1) UA55421C2 (xx)
WO (1) WO1998006722A1 (xx)
ZA (1) ZA977156B (xx)

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US6476078B2 (en) 1999-08-11 2002-11-05 Sepracor, Inc. Methods of using sibutramine metabolites in combination with a phosphodiesterase inhibitor to treat sexual dysfunction
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US6399826B1 (en) 1999-08-11 2002-06-04 Sepracor Inc. Salts of sibutramine metabolites, methods of making sibutramine metabolites and intermediates useful in the same, and methods of treating pain
DE10031585A1 (de) * 2000-06-29 2002-01-10 Merck Patent Gmbh 2-Aminoalkyl-thieno[2,3-d]pyrimidine
WO2002026745A1 (fr) * 2000-09-29 2002-04-04 Nippon Soda Co., Ltd. Composes de thienopyrimidine et leurs sels et procede de preparation
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WO2002083631A1 (en) 2001-04-13 2002-10-24 Sepracor Inc. Methods of preparing didesmethylsibutramine and other sibutramine derivatives
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JPWO2003035653A1 (ja) * 2001-10-26 2005-02-10 日本曹達株式会社 ピリドチエノピリミジン化合物およびその塩
US7153412B2 (en) 2001-12-28 2006-12-26 Kabushiki Kaisha Toyota Chuo Kenkyusho Electrodes, electrochemical elements, gas sensors, and gas measurement methods
US6962940B2 (en) 2002-03-20 2005-11-08 Celgene Corporation (+)-2-[1-(3-Ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione: methods of using and compositions thereof
US7276529B2 (en) 2002-03-20 2007-10-02 Celgene Corporation Methods of the treatment or prevention of exercise-induced asthma using (+)-2-[1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione
US7893101B2 (en) 2002-03-20 2011-02-22 Celgene Corporation Solid forms comprising (+)-2-[1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione, compositions thereof, and uses thereof
US7208516B2 (en) 2002-03-20 2007-04-24 Celgene Corporation Methods of the treatment of psoriatic arthritis using (+)-2-[1-(3-ethoxy-4-methoxyphenyl)-2-methylsulfonylethyl]-4-acetylaminoisoindoline-1,3-dione
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DE10351436A1 (de) * 2003-11-04 2005-06-09 Merck Patent Gmbh Verwendung von Thienopyrimidinen
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US9603848B2 (en) 2007-06-08 2017-03-28 Senomyx, Inc. Modulation of chemosensory receptors and ligands associated therewith
US9114138B2 (en) 2007-09-14 2015-08-25 Janssen Pharmaceuticals, Inc. 1′,3′-disubstituted-4-phenyl-3,4,5,6-tetrahydro-2H,1′H-[1,4′] bipyridinyl-2′-ones
EA019085B1 (ru) 2007-09-14 2014-01-30 Янссен Фармасьютикалз, Инк. 1',3-двузамещенные 4-(арил-х-фенил)-1н-пиридин-2-оны
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JP5433582B2 (ja) * 2007-11-14 2014-03-05 ジャンセン ファーマシューティカルズ, インコーポレイテッド. イミダゾ[1,2−a]ピリジン誘導体およびmGluR2受容体の正のアロステリック調節因子としてのその使用
US20100227853A1 (en) * 2008-04-18 2010-09-09 Trustees Of Boston College Inhibitors of cyclic amp phosphodiesterases
US8586733B2 (en) 2008-07-31 2013-11-19 Senomyx, Inc. Processes and intermediates for making sweet taste enhancers
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JP5852666B2 (ja) 2010-11-08 2016-02-03 ジヤンセン・フアーマシユーチカルズ・インコーポレーテツド 1,2,4−トリアゾロ[4,3−a]ピリジン誘導体およびmGluR2受容体のポジティブアロステリックモジュレーターとしてのそれらの使用
JP5852665B2 (ja) 2010-11-08 2016-02-03 ジヤンセン・フアーマシユーチカルズ・インコーポレーテツド 1,2,4−トリアゾロ[4,3−a]ピリジン誘導体およびmGluR2受容体のポジティブアロステリックモジュレーターとしてのそれらの使用
ES2552455T3 (es) 2010-11-08 2015-11-30 Janssen Pharmaceuticals, Inc. Derivados de 1,2,4-triazolo[4,3-a]piridina y su uso como moduladores alostéricos positivos de receptores mGluR2
JP6027611B2 (ja) 2011-07-19 2016-11-16 インフィニティー ファーマシューティカルズ, インコーポレイテッド 複素環式化合物及びその使用
WO2013106547A1 (en) 2012-01-10 2013-07-18 President And Fellows Of Harvard College Beta-cell replication promoting compounds and methods of their use
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JO3367B1 (ar) 2013-09-06 2019-03-13 Janssen Pharmaceutica Nv مركبات 2،1، 4- ثلاثي زولو [3،4-a] بيريدين واستخدامها بصفة منظمات تفارغية موجبة لمستقبلات ميجلور 2
LT3096790T (lt) 2014-01-21 2019-10-10 Janssen Pharmaceutica, N.V. Deriniai, apimantys 2 potipio metabotropinio glutamaterginio receptoriaus teigiamus alosterinius moduliatorius arba ortosterinius agonistus, ir jų panaudojimas
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Also Published As

Publication number Publication date
NO990643D0 (no) 1999-02-11
PT920431E (pt) 2003-07-31
PL190174B1 (pl) 2005-11-30
IL128504A (en) 2003-01-12
RU2199541C2 (ru) 2003-02-27
CN1081638C (zh) 2002-03-27
DE19632423A1 (de) 1998-02-19
WO1998006722A1 (de) 1998-02-19
CN1227560A (zh) 1999-09-01
AU4203597A (en) 1998-03-06
ZA977156B (en) 1998-02-19
AU725227B2 (en) 2000-10-12
CZ44899A3 (cs) 1999-05-12
KR100502271B1 (ko) 2005-07-22
BR9711062A (pt) 1999-08-17
TW359672B (en) 1999-06-01
NO990643L (no) 1999-02-11
DE59709404D1 (en) 2003-04-03
JP2000516223A (ja) 2000-12-05
ES2191192T3 (es) 2003-09-01
ATE233265T1 (de) 2003-03-15
EP0920431B1 (de) 2003-02-26
JP4405593B2 (ja) 2010-01-27
HK1021731A1 (en) 2000-06-30
CA2263561A1 (en) 1998-02-19
NZ334600A (en) 2000-07-28
PL331538A1 (en) 1999-07-19
UA55421C2 (uk) 2003-04-15
DK0920431T3 (da) 2003-06-02
TR199900308T2 (xx) 1999-04-21
HUP0001607A3 (en) 2002-09-30
KR20000029932A (ko) 2000-05-25
CA2263561C (en) 2007-02-20
SK16499A3 (en) 1999-06-11
US6110920A (en) 2000-08-29
HUP0001607A2 (hu) 2000-10-28
AR009052A1 (es) 2000-03-08
CZ287772B6 (en) 2001-01-17
EP0920431A1 (de) 1999-06-09
SK282823B6 (sk) 2002-12-03
IL128504A0 (en) 2000-01-31

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