RU2059635C1 - Производные бензопирана - Google Patents

Производные бензопирана Download PDF

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Publication number
RU2059635C1
RU2059635C1 SU914895678A SU4895678A RU2059635C1 RU 2059635 C1 RU2059635 C1 RU 2059635C1 SU 914895678 A SU914895678 A SU 914895678A SU 4895678 A SU4895678 A SU 4895678A RU 2059635 C1 RU2059635 C1 RU 2059635C1
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RU
Russia
Prior art keywords
dimethyl
dihydro
benzopyran
cyano
hydroxy
Prior art date
Application number
SU914895678A
Other languages
English (en)
Russian (ru)
Inventor
Атвал Карнайл
Original Assignee
Е.Р. Сквибб энд Санз, Инк.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Application filed by Е.Р. Сквибб энд Санз, Инк. filed Critical Е.Р. Сквибб энд Санз, Инк.
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Publication of RU2059635C1 publication Critical patent/RU2059635C1/ru

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/68—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with nitrogen atoms directly attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Quinoline Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
SU914895678A 1990-06-18 1991-06-17 Производные бензопирана RU2059635C1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US54042390A 1990-06-18 1990-06-18
US540423 1990-06-18

Publications (1)

Publication Number Publication Date
RU2059635C1 true RU2059635C1 (ru) 1996-05-10

Family

ID=24155395

Family Applications (1)

Application Number Title Priority Date Filing Date
SU914895678A RU2059635C1 (ru) 1990-06-18 1991-06-17 Производные бензопирана

Country Status (19)

Country Link
EP (1) EP0462761A3 (enExample)
JP (1) JPH04243852A (enExample)
KR (1) KR920000742A (enExample)
CN (1) CN1057461A (enExample)
AU (1) AU651105B2 (enExample)
CA (1) CA2043281A1 (enExample)
CS (1) CS185291A3 (enExample)
FI (1) FI912931L (enExample)
HU (1) HU210924B (enExample)
IE (1) IE911948A1 (enExample)
IL (1) IL98239A0 (enExample)
MX (1) MX26184A (enExample)
MY (1) MY107474A (enExample)
NO (1) NO178543C (enExample)
PL (3) PL166809B1 (enExample)
PT (1) PT98019A (enExample)
RU (1) RU2059635C1 (enExample)
TW (1) TW230772B (enExample)
ZA (1) ZA913923B (enExample)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2195459C2 (ru) * 1996-11-14 2002-12-27 Хехст Акциенгезелльшафт 3-амидо-хроманилсульфонил(тио)мочевины, способ их получения и фармацевтическая композиция на их основе
RU2208611C2 (ru) * 1997-09-26 2003-07-20 Авентис Фарма Дойчланд Гмбх Сульфонамидозамещенные хроманы и фармацевтическая композиция
RU2234502C2 (ru) * 1999-09-17 2004-08-20 Ниссан Кемикал Индастриз, Лтд. Бензопирановое производное и лекарственное средство на его основе
RU2288226C2 (ru) * 2001-02-14 2006-11-27 Ниссан Кемикал Индастриз, Лтд. Производные 4-аминобензопирана

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5453421A (en) * 1992-09-11 1995-09-26 E. R. Squibb & Sons, Inc. Aryl and heterocyclic substituted propenamide derivatives
US5374643A (en) * 1992-09-11 1994-12-20 E. R. Squibb & Sons, Inc. Aryl urea (thiourea) and cyanoguanidine derivatives
US5514690A (en) * 1992-11-17 1996-05-07 E. R. Squibb & Sons, Inc. Aminocarbonyl (thiocarbonyl) and cyanoguanidine derivatives of quinoline and indoline
IL109229A0 (en) * 1993-05-11 1994-07-31 Bristol Myers Squibb Co Heterocyclic compounds and processes for the preparation of pyranyl cyanoguanidine derivatives using the same
US5393771A (en) * 1993-05-12 1995-02-28 Brisol-Myers Squibb Company 4-substituted benzopyran and related compounds
TW310327B (enExample) * 1993-06-18 1997-07-11 Bristol Myers Squibb Co
US5869478A (en) * 1995-06-07 1999-02-09 Bristol-Myers Squibb Company Sulfonamido substituted benzopyran derivatives
US5612370A (en) * 1995-06-07 1997-03-18 Bristol-Myers Squibb Company Phenylglycine and phenylalaninen amido benzopyran derivatives
US5612323A (en) * 1995-06-07 1997-03-18 Bristol-Myers Squibb Company Phosphinic ester substituted benzopyran derivatives
US5629429A (en) * 1995-06-07 1997-05-13 Bristol-Myers Squibb Company Process for preparing 4-arylamino-benzopyran and related compounds
US6262269B1 (en) * 1997-02-04 2001-07-17 Trega Biosciences, Inc. 4-Substituted-quinoline derivatives and 4-substituted-quinoline combinatorial libraries
GB0028697D0 (en) * 2000-11-23 2001-01-10 S P A Novel process
DE60206505T2 (de) 2001-06-25 2006-07-06 Nissan Chemical Industries, Ltd. Substituierte benzopyranderivate gegen arrhytmie
AR039283A1 (es) * 2002-04-10 2005-02-16 Dongbu Hannong Chemical Co Ltd Derivados de benzopirano sustituidos con aminas secundarias que incluyen tetrazol, metodo para su preparacion y composiciones farmaceuticas que los contienen
KR100545780B1 (ko) * 2003-05-28 2006-01-24 동부한농화학 주식회사 벤즈이미다졸 유도체로 치환된 벤조피란 유도체 또는약학적으로 허용되는 그의 염, 이의 제조 방법 및 이를포함하는 약학적 조성물
KR100512486B1 (ko) * 2003-05-28 2005-09-06 동부한농화학 주식회사 싸이옥소벤즈옥사졸 유도체로 치환된 벤조피란 유도체또는 약학적으로 허용되는 염, 이의 제조방법 및 이를포함하는 약학적 조성물
WO2005014586A1 (en) * 2003-08-08 2005-02-17 Arpida Ag Novel process for the preparation of 2h-chromenes
EP1589015A1 (en) * 2004-02-03 2005-10-26 Université de Liège Benzopyran derivatives, method of production and use thereof
EP1931681B1 (en) 2005-10-07 2012-11-14 Glenmark Pharmaceuticals S.A. Substituted benzofused derivatives and their use as vanilloid receptor ligands
WO2009095726A1 (en) * 2008-01-29 2009-08-06 Glenmark Pharmaceuticals, S.A. Acrylamide derivatives as vanilloid receptor 1 modulators

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3486354T2 (de) * 1983-05-18 1995-03-30 Beecham Group Plc Chroman- und Chromenderivate.
ES2058148T3 (es) * 1987-02-04 1994-11-01 Hoechst Ag N-benzopiranil-lactamas sustituidas con alquilo, procedimiento para su preparacion, su empleo, asi como preparados farmaceuticos a base de estos compuestos.
DE3901720A1 (de) * 1989-01-21 1990-07-26 Hoechst Ag Substituierte benzo(b)pyrane, verfahren zu ihrer herstellung, ihre verwendung sowie pharmazeutische praeparate auf basis dieser verbindungen
CA2015296C (en) * 1989-05-31 2001-08-07 Karnail Atwal Pyranyl cyanoguanidine derivatives
US5401848A (en) * 1990-11-26 1995-03-28 E. R. Squibb & Sons, Inc. Indane and quinoline derivatives

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2195459C2 (ru) * 1996-11-14 2002-12-27 Хехст Акциенгезелльшафт 3-амидо-хроманилсульфонил(тио)мочевины, способ их получения и фармацевтическая композиция на их основе
RU2208611C2 (ru) * 1997-09-26 2003-07-20 Авентис Фарма Дойчланд Гмбх Сульфонамидозамещенные хроманы и фармацевтическая композиция
RU2234502C2 (ru) * 1999-09-17 2004-08-20 Ниссан Кемикал Индастриз, Лтд. Бензопирановое производное и лекарственное средство на его основе
RU2288226C2 (ru) * 2001-02-14 2006-11-27 Ниссан Кемикал Индастриз, Лтд. Производные 4-аминобензопирана

Also Published As

Publication number Publication date
IE911948A1 (en) 1991-12-18
AU7710291A (en) 1991-12-19
KR920000742A (ko) 1992-01-29
EP0462761A3 (en) 1992-01-22
NO178543B (no) 1996-01-08
CN1057461A (zh) 1992-01-01
TW230772B (enExample) 1994-09-21
CA2043281A1 (en) 1991-12-19
MX26184A (es) 1993-10-01
NO178543C (no) 1996-04-17
ZA913923B (en) 1992-02-26
NO912344L (no) 1991-12-19
FI912931A0 (fi) 1991-06-17
HUT58066A (en) 1992-01-28
MY107474A (en) 1995-12-31
HU912013D0 (en) 1991-12-30
PL290720A1 (en) 1992-03-23
NO912344D0 (no) 1991-06-17
PL167832B1 (pl) 1995-11-30
PL166787B1 (pl) 1995-06-30
FI912931A7 (fi) 1991-12-19
EP0462761A2 (en) 1991-12-27
JPH04243852A (ja) 1992-08-31
FI912931L (fi) 1991-12-19
IL98239A0 (en) 1992-06-21
CS185291A3 (en) 1992-04-15
HU210924B (en) 1995-09-28
AU651105B2 (en) 1994-07-14
PL166809B1 (pl) 1995-06-30
PT98019A (pt) 1992-04-30

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