FI912931A0 - Benzopyranderivat och deras heterocykliska analoger som antiischemiska medel. - Google Patents

Benzopyranderivat och deras heterocykliska analoger som antiischemiska medel.

Info

Publication number
FI912931A0
FI912931A0 FI912931A FI912931A FI912931A0 FI 912931 A0 FI912931 A0 FI 912931A0 FI 912931 A FI912931 A FI 912931A FI 912931 A FI912931 A FI 912931A FI 912931 A0 FI912931 A0 FI 912931A0
Authority
FI
Finland
Prior art keywords
benzopyranderivat
antiischemiska
heterocycliska
analoger
medel
Prior art date
Application number
FI912931A
Other languages
English (en)
Other versions
FI912931A (fi
Inventor
Karnail Atwal
Original Assignee
Squibb & Sons Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Squibb & Sons Inc filed Critical Squibb & Sons Inc
Publication of FI912931A0 publication Critical patent/FI912931A0/fi
Publication of FI912931A publication Critical patent/FI912931A/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D311/00Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • C07D311/68Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4 with nitrogen atoms directly attached in position 4
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Hematology (AREA)
  • Diabetes (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Quinoline Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
FI912931A 1990-06-18 1991-06-17 Benzopyranderivat och deras heterocykliska analoger som antiischemiska medel. FI912931A (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US54042390A 1990-06-18 1990-06-18

Publications (2)

Publication Number Publication Date
FI912931A0 true FI912931A0 (fi) 1991-06-17
FI912931A FI912931A (fi) 1991-12-19

Family

ID=24155395

Family Applications (1)

Application Number Title Priority Date Filing Date
FI912931A FI912931A (fi) 1990-06-18 1991-06-17 Benzopyranderivat och deras heterocykliska analoger som antiischemiska medel.

Country Status (19)

Country Link
EP (1) EP0462761A3 (fi)
JP (1) JPH04243852A (fi)
KR (1) KR920000742A (fi)
CN (1) CN1057461A (fi)
AU (1) AU651105B2 (fi)
CA (1) CA2043281A1 (fi)
CS (1) CS185291A3 (fi)
FI (1) FI912931A (fi)
HU (1) HU210924B (fi)
IE (1) IE911948A1 (fi)
IL (1) IL98239A0 (fi)
MX (1) MX26184A (fi)
MY (1) MY107474A (fi)
NO (1) NO178543C (fi)
PL (3) PL166787B1 (fi)
PT (1) PT98019A (fi)
RU (1) RU2059635C1 (fi)
TW (1) TW230772B (fi)
ZA (1) ZA913923B (fi)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5374643A (en) * 1992-09-11 1994-12-20 E. R. Squibb & Sons, Inc. Aryl urea (thiourea) and cyanoguanidine derivatives
US5453421A (en) * 1992-09-11 1995-09-26 E. R. Squibb & Sons, Inc. Aryl and heterocyclic substituted propenamide derivatives
US5514690A (en) * 1992-11-17 1996-05-07 E. R. Squibb & Sons, Inc. Aminocarbonyl (thiocarbonyl) and cyanoguanidine derivatives of quinoline and indoline
IL109229A0 (en) * 1993-05-11 1994-07-31 Bristol Myers Squibb Co Heterocyclic compounds and processes for the preparation of pyranyl cyanoguanidine derivatives using the same
US5393771A (en) * 1993-05-12 1995-02-28 Brisol-Myers Squibb Company 4-substituted benzopyran and related compounds
TW310327B (fi) * 1993-06-18 1997-07-11 Bristol Myers Squibb Co
US5612370A (en) * 1995-06-07 1997-03-18 Bristol-Myers Squibb Company Phenylglycine and phenylalaninen amido benzopyran derivatives
US5612323A (en) * 1995-06-07 1997-03-18 Bristol-Myers Squibb Company Phosphinic ester substituted benzopyran derivatives
US5629429A (en) * 1995-06-07 1997-05-13 Bristol-Myers Squibb Company Process for preparing 4-arylamino-benzopyran and related compounds
US5869478A (en) * 1995-06-07 1999-02-09 Bristol-Myers Squibb Company Sulfonamido substituted benzopyran derivatives
US6262269B1 (en) * 1997-02-04 2001-07-17 Trega Biosciences, Inc. 4-Substituted-quinoline derivatives and 4-substituted-quinoline combinatorial libraries
GB0028697D0 (en) * 2000-11-23 2001-01-10 S P A Novel process
NZ529916A (en) 2001-06-25 2005-04-29 Nissan Chemical Ind Ltd Substituted benzopyran derivatives against arrhythmia
AU2003218824A1 (en) * 2002-04-10 2003-10-20 Dongbu Hannong Chemical Co., Ltd Benzopyran derivatives substituted with secondary amines including tetrazole, method for the preparation thereof and pharmaceutical compositions containing them
KR100545780B1 (ko) * 2003-05-28 2006-01-24 동부한농화학 주식회사 벤즈이미다졸 유도체로 치환된 벤조피란 유도체 또는약학적으로 허용되는 그의 염, 이의 제조 방법 및 이를포함하는 약학적 조성물
KR100512486B1 (ko) * 2003-05-28 2005-09-06 동부한농화학 주식회사 싸이옥소벤즈옥사졸 유도체로 치환된 벤조피란 유도체또는 약학적으로 허용되는 염, 이의 제조방법 및 이를포함하는 약학적 조성물
WO2005014586A1 (en) * 2003-08-08 2005-02-17 Arpida Ag Novel process for the preparation of 2h-chromenes
EP1589015A1 (en) * 2004-02-03 2005-10-26 Université de Liège Benzopyran derivatives, method of production and use thereof
EA200801013A1 (ru) 2005-10-07 2008-10-30 Гленмарк Фармасеутикалс С.А. Производные замещённых соединений, содержащих конденсированные бензольные кольца, и их применение в качестве лигандов ванилоидных рецепторов
WO2009095726A1 (en) * 2008-01-29 2009-08-06 Glenmark Pharmaceuticals, S.A. Acrylamide derivatives as vanilloid receptor 1 modulators

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3486354T2 (de) * 1983-05-18 1995-03-30 Beecham Group Plc Chroman- und Chromenderivate.
DE3881714D1 (de) * 1987-02-04 1993-07-22 Hoechst Ag Alkylsubstituierte n-benzopyranyllactame, verfahren zu ihrer herstellung, ihre verwendung sowie pharmazeutische praeparate auf basis dieser verbindungen.
DE3901720A1 (de) * 1989-01-21 1990-07-26 Hoechst Ag Substituierte benzo(b)pyrane, verfahren zu ihrer herstellung, ihre verwendung sowie pharmazeutische praeparate auf basis dieser verbindungen
CA2015296C (en) * 1989-05-31 2001-08-07 Karnail Atwal Pyranyl cyanoguanidine derivatives
US5401848A (en) * 1990-11-26 1995-03-28 E. R. Squibb & Sons, Inc. Indane and quinoline derivatives

Also Published As

Publication number Publication date
PL167832B1 (pl) 1995-11-30
CA2043281A1 (en) 1991-12-19
MX26184A (es) 1993-10-01
MY107474A (en) 1995-12-31
RU2059635C1 (ru) 1996-05-10
AU7710291A (en) 1991-12-19
NO178543B (no) 1996-01-08
FI912931A (fi) 1991-12-19
NO912344L (no) 1991-12-19
ZA913923B (en) 1992-02-26
HU210924B (en) 1995-09-28
PL166809B1 (pl) 1995-06-30
CS185291A3 (en) 1992-04-15
PL290720A1 (en) 1992-03-23
HU912013D0 (en) 1991-12-30
TW230772B (fi) 1994-09-21
EP0462761A3 (en) 1992-01-22
CN1057461A (zh) 1992-01-01
JPH04243852A (ja) 1992-08-31
HUT58066A (en) 1992-01-28
NO178543C (no) 1996-04-17
IL98239A0 (en) 1992-06-21
IE911948A1 (en) 1991-12-18
NO912344D0 (no) 1991-06-17
AU651105B2 (en) 1994-07-14
EP0462761A2 (en) 1991-12-27
PL166787B1 (pl) 1995-06-30
PT98019A (pt) 1992-04-30
KR920000742A (ko) 1992-01-29

Similar Documents

Publication Publication Date Title
FI912119A (fi) Medel som foerbaettrar aromen och maskerar sidosmak, och deras anvaendning.
FI921952A0 (fi) Foerfarande foer framstaellning av dialkylenpiperidinofoereningar och enantiomerer daerav anvaendbara som laekemedel.
FI915387A (fi) Tuggummi, som avger smak under en foerlaengd tidsperiod och som innehaoller omaettade, renade monoglycerider.
FI862256A (fi) Grundmjukgoerare som innehaoller katjoniskt ytaktivt medel och organisk syra.
FI893105A (fi) Tryckkapsel foer spraybehaollare och spraybehaollare som utnyttjar en saodan kapsel.
FI903929A0 (fi) Proteiner som induserar immunologisk effektorcellaktivation och kemattraktion.
FI922277A0 (fi) Icke-replicerande, medelst rekombinant-teknik framstaellda retrovirala partiklar, vilka anvaendes som antivirala medel och immunogener.
FI922454A0 (fi) Peptider och antikroppar som inhiberar integrinligandbindning.
FI923558A0 (fi) Tetrahydroindazol-, tetrahydrocyklo -pentapyrazol- och hexahydrocykloheptapyrazolfoereningar och deras anvaendning som inhibitorer av hmg-coa-reduktas.
FI912931A0 (fi) Benzopyranderivat och deras heterocykliska analoger som antiischemiska medel.
FI892448A0 (fi) Klibbningsfoerhindrande och sedimenterande medel foer maolarfaerg.
FI923756A0 (fi) Polyolefinkompositioner som omfattar glycerolmonoestrar av c20-24-fettsyror och daerav framstaellda skumprodukter.
FI923185A0 (fi) Foerfarande och anordning foer framstaellning av fogloesa band- och traodoeglor och deras anvaendning som kapverktyg i band- och traodsaogar.
FI911863A0 (fi) Metylendifosfonsyra och antiinflammatoriskt medel innehaollande denna foerening som aktivkomponent.
FI921596A0 (fi) Tetron- och tietetronsyraderivat och fosfolifas a2 som inhibitorer.
FI913138A0 (fi) Foerfarande foer framstaellning av b -laktamer som innehaoller aminotiazol(iminooxiaettiksyra) aettiksyrasidokedjor och mellanprodukter daerav.
FI911171A0 (fi) Vaermeoeverfoeringsblaeckkomposition och medel.
FI915609A (fi) Foerfarande och anordning foer styrning av en m-pulsvaexelriktaranordning som bestaor av en mastervaexelriktare och aotminstone en slavvaexelriktare.
FI914556A0 (fi) 4- eller 5-substituerade pyridiner-2-karboxylsyror, foerfarande foer deras framstaellning och deras anvaendning som laekemedel.
FI922472A0 (fi) Gingerol- och gingerdiolderivat som hypokolesterolemiska och antiaterosklerostiska medel.
FI883315A (fi) 1h-pyrazol-1-alkanamider anvaendbara som antiarrytmiska medel och deras framstaellning.
FI892207A0 (fi) 2-adamantyl-4-isotiazolin-3-oner, deras tillverkningsfoerfarande och anvaendning som baktericida och fungicida medel.
FI910208A (fi) Fungicida medel.
FI914557A (fi) 4- eller 5-substituerade pyridiner-2 karboxylsyror, foerfarande foer deras frmstaellning och deras anvaendning som laekemedel.
FI890974A0 (fi) Funktionella kronetrar, foerfarande foer deras framstaellning och deras anvaendning som komplexbildande medel foer joner.

Legal Events

Date Code Title Description
FD Application lapsed