RU2016103067A - Улучшенные аминокислотные последовательности, направленные против респираторно-синцитиального вируса человека (hrsv), и полипептиды, включающие такие последовательности, для профилактики и/или лечения инфекций дыхательных путей - Google Patents
Улучшенные аминокислотные последовательности, направленные против респираторно-синцитиального вируса человека (hrsv), и полипептиды, включающие такие последовательности, для профилактики и/или лечения инфекций дыхательных путей Download PDFInfo
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- RU2016103067A RU2016103067A RU2016103067A RU2016103067A RU2016103067A RU 2016103067 A RU2016103067 A RU 2016103067A RU 2016103067 A RU2016103067 A RU 2016103067A RU 2016103067 A RU2016103067 A RU 2016103067A RU 2016103067 A RU2016103067 A RU 2016103067A
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- gln108leu
- ala14pro
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- single variable
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Classifications
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- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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- C07K2317/565—Complementarity determining region [CDR]
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- C—CHEMISTRY; METALLURGY
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- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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- C07K2317/567—Framework region [FR]
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- C—CHEMISTRY; METALLURGY
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- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
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- C07K2317/569—Single domain, e.g. dAb, sdAb, VHH, VNAR or nanobody®
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- C—CHEMISTRY; METALLURGY
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- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
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- C07K2317/626—Diabody or triabody
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- C—CHEMISTRY; METALLURGY
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- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/90—Immunoglobulins specific features characterized by (pharmaco)kinetic aspects or by stability of the immunoglobulin
- C07K2317/92—Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
Landscapes
- Health & Medical Sciences (AREA)
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- Organic Chemistry (AREA)
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- Otolaryngology (AREA)
- Communicable Diseases (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US18439609P | 2009-06-05 | 2009-06-05 | |
| US61/184,396 | 2009-06-05 | ||
| US26501409P | 2009-11-30 | 2009-11-30 | |
| US61/265,014 | 2009-11-30 |
Related Parent Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2011153239/10A Division RU2577134C2 (ru) | 2009-06-05 | 2010-06-07 | Улучшенные аминокислотные последовательности, направленные против респираторно-синцитиального вируса человека (hrsv), и полипептиды, включающие такие последовательности, для профилактики и/или лечения инфекций дыхательных путей |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| RU2016103067A true RU2016103067A (ru) | 2018-11-20 |
| RU2016103067A3 RU2016103067A3 (fr) | 2019-08-08 |
Family
ID=42333502
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2016103067A RU2016103067A (ru) | 2009-06-05 | 2010-06-07 | Улучшенные аминокислотные последовательности, направленные против респираторно-синцитиального вируса человека (hrsv), и полипептиды, включающие такие последовательности, для профилактики и/или лечения инфекций дыхательных путей |
| RU2011153239/10A RU2577134C2 (ru) | 2009-06-05 | 2010-06-07 | Улучшенные аминокислотные последовательности, направленные против респираторно-синцитиального вируса человека (hrsv), и полипептиды, включающие такие последовательности, для профилактики и/или лечения инфекций дыхательных путей |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| RU2011153239/10A RU2577134C2 (ru) | 2009-06-05 | 2010-06-07 | Улучшенные аминокислотные последовательности, направленные против респираторно-синцитиального вируса человека (hrsv), и полипептиды, включающие такие последовательности, для профилактики и/или лечения инфекций дыхательных путей |
Country Status (25)
| Country | Link |
|---|---|
| US (3) | US8945567B2 (fr) |
| EP (2) | EP2438087B1 (fr) |
| JP (2) | JP6081196B2 (fr) |
| KR (1) | KR101852204B1 (fr) |
| CN (2) | CN102459332B (fr) |
| AU (1) | AU2010255638B2 (fr) |
| BR (1) | BRPI1010830A2 (fr) |
| CA (1) | CA2764398A1 (fr) |
| CY (1) | CY1119265T1 (fr) |
| DK (1) | DK2438087T3 (fr) |
| ES (1) | ES2643034T3 (fr) |
| HR (1) | HRP20171194T1 (fr) |
| HU (1) | HUE035773T2 (fr) |
| IL (1) | IL216341A0 (fr) |
| LT (1) | LT2438087T (fr) |
| MX (1) | MX340541B (fr) |
| NZ (1) | NZ597314A (fr) |
| PH (1) | PH12019500644A1 (fr) |
| PL (1) | PL2438087T3 (fr) |
| PT (1) | PT2438087T (fr) |
| RU (2) | RU2016103067A (fr) |
| SG (1) | SG176095A1 (fr) |
| SI (1) | SI2438087T1 (fr) |
| WO (1) | WO2010139808A2 (fr) |
| ZA (1) | ZA201108892B (fr) |
Families Citing this family (31)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SI2285408T1 (sl) | 2008-06-05 | 2019-02-28 | Ablynx N.V. | Aminokislinska zaporedja usmerjena proti proteinom ovojnicam virusa in polipeptidi, ki zaporedja vsebujejo za zdravljenje virusnih bolezni |
| RU2016103067A (ru) | 2009-06-05 | 2018-11-20 | Аблинкс Нв | Улучшенные аминокислотные последовательности, направленные против респираторно-синцитиального вируса человека (hrsv), и полипептиды, включающие такие последовательности, для профилактики и/или лечения инфекций дыхательных путей |
| US9644022B2 (en) | 2009-11-30 | 2017-05-09 | Ablynx N.V. | Amino acid sequences directed against human respiratory syncytial virus (HRSV) and polypeptides comprising the same for the prevention and/or treatment of respiratory tract infections |
| US8962807B2 (en) | 2009-12-14 | 2015-02-24 | Ablynx N.V. | Single variable domain antibodies against OX40L, constructs and therapeutic use |
| PL2533761T3 (pl) | 2010-02-11 | 2019-09-30 | Ablynx N.V. | Sposoby i kompozycje do wytwarzania aerozoli |
| WO2012056000A1 (fr) | 2010-10-29 | 2012-05-03 | Ablynx Nv | Procédé de production de domaines variables uniques d'immunoglobuline |
| EP2707382B1 (fr) | 2011-05-09 | 2019-07-17 | Ablynx NV | Procédé pour la production de domaines variables uniques d'immunoglobuline |
| US11339208B1 (en) | 2012-05-31 | 2022-05-24 | United States Of America As Represented By The Secretary Of The Air Force | Camelidae single-domain antibodies against Yersinia pestis and methods of use |
| SI2968520T1 (sl) | 2013-03-14 | 2022-01-31 | Macrogenics, Inc. | Bispecifične molekule, ki so imunoreaktivne z imunskimi efektorskimi celicami, ki izražajo aktivacijski receptor |
| JP6485817B2 (ja) | 2013-08-21 | 2019-03-20 | ヤンセン バイオファーマ インク． | 抗ウイルス化合物 |
| WO2016022464A1 (fr) * | 2014-08-05 | 2016-02-11 | Alios Biopharma, Inc. | Polythérapie pour traiter un paramyxovirus |
| AU2015323860B2 (en) | 2014-09-29 | 2021-05-27 | Duke University | Bispecific molecules comprising an HIV-1 envelope targeting arm |
| KR102364212B1 (ko) | 2014-10-10 | 2022-02-17 | 아블린쓰 엔.브이. | 호흡기 질병들의 에어로졸 치료에 사용하기 위한 흡입 디바이스 |
| AU2015329936A1 (en) * | 2014-10-10 | 2017-04-20 | Ablynx N.V. | Methods of treating RSV infections |
| MA41614A (fr) | 2015-02-25 | 2018-01-02 | Alios Biopharma Inc | Composés antiviraux |
| EP3313432A1 (fr) * | 2015-06-18 | 2018-05-02 | VIB vzw | Anticorps à domaine variable unique d'immunoglobuline contre la protéine f de pré-fusion de rsv |
| EP3124042A1 (fr) * | 2015-07-28 | 2017-02-01 | VIB, vzw | Anticorps à domaine variable unique contre la protéine f prefusion du virus respiratoire syncytial (rsv) |
| CN109311968A (zh) | 2016-05-02 | 2019-02-05 | 埃博灵克斯股份有限公司 | 治疗rsv感染 |
| SG11201811280QA (en) | 2016-06-23 | 2019-01-30 | Ablynx Nv | Improved pharmacokinetic assays for immunoglobulin single variable domains |
| CN106279410B (zh) * | 2016-09-29 | 2019-08-20 | 华南理工大学 | 一种二型登革热病毒ns1蛋白多价纳米抗体及制备方法 |
| JP7265984B2 (ja) | 2016-10-21 | 2023-04-27 | アディマブ， エルエルシー | 抗呼吸器合胞体ウイルス抗体、及び、それらの生成及び使用の方法 |
| IL303833A (en) | 2016-10-21 | 2023-08-01 | Adimab Llc | Respiratory syncytial virus antibodies and methods for their production and use |
| JP2020503843A (ja) | 2016-10-21 | 2020-02-06 | アディマブ， エルエルシー | 抗呼吸器合胞体ウイルス抗体、及び、それらの生成及び使用の方法 |
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