RO87590A - Procedeu de preparare a interferenului de leucocita umana matura - Google Patents

Procedeu de preparare a interferenului de leucocita umana matura

Info

Publication number
RO87590A
RO87590A RO81104732A RO10473281A RO87590A RO 87590 A RO87590 A RO 87590A RO 81104732 A RO81104732 A RO 81104732A RO 10473281 A RO10473281 A RO 10473281A RO 87590 A RO87590 A RO 87590A
Authority
RO
Romania
Prior art keywords
leukocita
matura
interference
human
preparation
Prior art date
Application number
RO81104732A
Other languages
English (en)
French (fr)
Romanian (ro)
Inventor
David Van N Goeddel
Sidney Pestka
Original Assignee
Hoffmann-La Roche & Co.Ag,Ch
Genentech Inc,Us
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27496622&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=RO87590(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US06/256,204 external-priority patent/US6610830B1/en
Application filed by Hoffmann-La Roche & Co.Ag,Ch, Genentech Inc,Us filed Critical Hoffmann-La Roche & Co.Ag,Ch
Publication of RO87590A publication Critical patent/RO87590A/ro

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • C07K14/56—IFN-alpha
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C12N15/71—Expression systems using regulatory sequences derived from the trp-operon
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00—Preparation of peptides or proteins
    • C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
RO81104732A 1980-07-01 1981-06-30 Procedeu de preparare a interferenului de leucocita umana matura RO87590A (ro)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US16498680A 1980-07-01 1980-07-01
US18490980A 1980-09-08 1980-09-08
US20557880A 1980-11-10 1980-11-10
US06/256,204 US6610830B1 (en) 1980-07-01 1981-04-21 Microbial production of mature human leukocyte interferons

Publications (1)

Publication Number Publication Date
RO87590A true RO87590A (ro) 1986-07-30

Family

ID=27496622

Family Applications (1)

Application Number Title Priority Date Filing Date
RO81104732A RO87590A (ro) 1980-07-01 1981-06-30 Procedeu de preparare a interferenului de leucocita umana matura

Country Status (36)

Country Link
EP (2) EP0211148B2 (en:Method)
AR (1) AR242833A1 (en:Method)
AT (3) ATE29727T1 (en:Method)
AU (1) AU552004B2 (en:Method)
BG (1) BG42189A3 (en:Method)
BR (1) BR8104189A (en:Method)
CH (2) CH651308A5 (en:Method)
CS (1) CS273152B2 (en:Method)
DD (3) DD210305A5 (en:Method)
DE (3) DE3176448D1 (en:Method)
DK (1) DK173543B1 (en:Method)
DZ (1) DZ312A1 (en:Method)
ES (1) ES503528A0 (en:Method)
FI (1) FI82712C (en:Method)
FR (1) FR2486098B1 (en:Method)
GB (1) GB2079291B (en:Method)
GE (1) GEP19960519B (en:Method)
GR (1) GR75714B (en:Method)
HK (1) HK49285A (en:Method)
HU (1) HU196457B (en:Method)
IE (1) IE49255B1 (en:Method)
IT (1) IT1137272B (en:Method)
KE (1) KE3534A (en:Method)
LU (1) LU83461A1 (en:Method)
MC (1) MC1396A1 (en:Method)
MY (1) MY8700711A (en:Method)
NL (1) NL8103151A (en:Method)
NO (1) NO159392C (en:Method)
NZ (1) NZ197572A (en:Method)
PH (1) PH18036A (en:Method)
PL (3) PL148260B1 (en:Method)
PT (1) PT73289B (en:Method)
RO (1) RO87590A (en:Method)
SE (2) SE465223C5 (en:Method)
SU (1) SU1414319A3 (en:Method)
YU (1) YU47700B (en:Method)

Families Citing this family (51)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA811368B (en) 1980-03-24 1982-04-28 Genentech Inc Bacterial polypedtide expression employing tryptophan promoter-operator
GR74498B (en:Method) 1980-04-03 1984-06-28 Biogen Inc
EP0042246B1 (en) * 1980-06-12 1987-03-18 The Cancer Institute Of Japanese Foundation For Cancer Research Plasmid
DK489481A (da) * 1980-11-10 1982-05-11 Searle & Co Plasmidvektor og frmgangsmaade til fremstilling deraf
NZ199722A (en) * 1981-02-25 1985-12-13 Genentech Inc Dna transfer vector for expression of exogenous polypeptide in yeast;transformed yeast strain
WO1983000693A1 (en) * 1981-08-14 1983-03-03 Berg, Kurt, Frimann SUBJECTS RELATING TO HUMAN INTEFERON-'alpha' SUBTYPE PROTEINS AND CORRESPONDING ANTIBODIES
JPS58110548A (ja) * 1981-12-24 1983-07-01 Asahi Chem Ind Co Ltd 新規な生理活性ペプチド
US4973479A (en) * 1982-01-15 1990-11-27 Cetus Corporation Interferon-α61
US5098703A (en) * 1982-01-15 1992-03-24 Cetus Corporation Interferon-alpha 76
US4975276A (en) * 1982-01-15 1990-12-04 Cetus Corporation Interferon-alpha 54
IE54592B1 (en) * 1982-03-08 1989-12-06 Genentech Inc Anumal interferons, processes involved in their production, compositions containing them, dna sequences coding therefor and espression vehicles containing such sequences and cells transformed thereby
US5827694A (en) * 1982-03-08 1998-10-27 Genentech, Inc. DNA encoding non-human animal interferons, vectors and hosts therefor, and recombinant production of IFN polypeptides
US6432677B1 (en) 1982-03-08 2002-08-13 Genentech, Inc. Non-human animal interferons
US4775622A (en) * 1982-03-08 1988-10-04 Genentech, Inc. Expression, processing and secretion of heterologous protein by yeast
EP0088994B1 (en) * 1982-03-15 1991-06-19 Schering Corporation Hybrid dna, binding composition prepared thereby and processes therefor
US4695543A (en) * 1982-03-23 1987-09-22 Bristol-Myers Company Alpha Interferon GX-1
CA1210714A (en) * 1982-03-23 1986-09-02 Alan Sloma .alpha.-INTERFERON GX-1
US4748233A (en) * 1982-03-23 1988-05-31 Bristol-Myers Company Alpha-interferon Gx-1
US6936694B1 (en) 1982-05-06 2005-08-30 Intermune, Inc. Manufacture and expression of large structural genes
US5831023A (en) * 1982-11-01 1998-11-03 Genentech, Inc. Recombinant animal interferon polypeptides
FR2541579B1 (fr) * 1983-02-24 1987-12-18 Inst Organicheskogo Sinteza Ak Interferon n leucocytaire humain et procede d'obtention de celui-ci dans les cellules bacteriennes
EP0165942A1 (en) * 1983-12-23 1986-01-02 Monash University PRODUCTION OF HUMAN INTERFERON-$g(a)
SU1364343A1 (ru) * 1984-07-13 1988-01-07 Всесоюзный научно-исследовательский институт генетики и селекции промышленных микроорганизмов Способ получени человеческого лейкоцитарного интерферона альфа-2
WO1986002068A1 (en) * 1984-09-26 1986-04-10 Takeda Chemical Industries, Ltd. Mutual separation of proteins
IL76360A0 (en) 1984-09-26 1986-01-31 Takeda Chemical Industries Ltd Mutual separation of proteins
DE3515336C2 (de) * 1985-04-27 1994-01-20 Boehringer Ingelheim Int Verfahren zur Herstellung und Reinigung von â-Interferon
US5196323A (en) * 1985-04-27 1993-03-23 Boehringer Ingelheim International Gmbh Process for preparing and purifying alpha-interferon
JP2514950B2 (ja) * 1986-03-10 1996-07-10 エフ・ホフマン―ラ ロシユ アーゲー 化学修飾蛋白質，その製造法および中間体
JPS6463395A (en) * 1987-05-04 1989-03-09 Oncogen Oncostatin m and novel composition having antitumor activity
CA1309044C (en) * 1987-11-09 1992-10-20 Toshiya Takano Method of producing foreign gene products
GB8813032D0 (en) * 1988-06-02 1988-07-06 Boehringer Ingelheim Int Antiviral pharmaceutical composition
WO1991003251A1 (en) * 1989-09-08 1991-03-21 California Institute Of Biological Research Cr2 ligand compositions and methods for modulating immune cell functions
DE3932311A1 (de) * 1989-09-28 1991-04-11 Boehringer Ingelheim Int Verfahren zur reinigung von beta-interferon
EP0741577B1 (en) * 1994-03-07 2002-11-06 IMPERIAL COLLEGE OF SCIENCE, TECHNOLOGY & MEDICINE The use of interferon subtype alpha 8 in the preparation of medicaments to treat viral infections of the liver
ES2161793T3 (es) * 1994-04-09 2001-12-16 Hoffmann La Roche Proceso para la produccion de alfa-interferona.
GB9609932D0 (en) * 1996-05-13 1996-07-17 Hoffmann La Roche Use of IL-12 and IFN alpha for the treatment of infectious diseases
US20030190307A1 (en) 1996-12-24 2003-10-09 Biogen, Inc. Stable liquid interferon formulations
ZA9811070B (en) 1997-12-08 2000-07-03 Genentech Inc Type I interferons.
US6299869B1 (en) 1997-12-08 2001-10-09 Genentech, Inc. Human interferon-epsilon: a type I interferon
US6783965B1 (en) 2000-02-10 2004-08-31 Mountain View Pharmaceuticals, Inc. Aggregate-free urate oxidase for preparation of non-immunogenic polymer conjugates
CN1896231B (zh) 1998-08-06 2012-09-05 山景药品公司 分离四聚体尿酸氧化酶的方法
US6268178B1 (en) 1999-05-25 2001-07-31 Phage Biotechnology Corp. Phage-dependent super-production of biologically active protein and peptides
IL155741A0 (en) * 2000-11-03 2003-12-23 Pbl Biomedical Lab Interferons, uses and compositions related thereto
FR2822845B1 (fr) 2001-03-30 2003-12-12 Genodyssee Nouveaux polynucleotides comportant des polymorphismes de type snp fonctionnels dans la sequence nucleotidique du gene ifn-alpha-21 ainsi que de nouveaux polypeptides codes par ces polynucleotides et leurs utilisations therapeutiques
FR2823220B1 (fr) 2001-04-04 2003-12-12 Genodyssee Nouveaux polynucleotides et polypeptides de l'erythropoietine (epo)
FR2825716B1 (fr) 2001-06-11 2004-09-24 Genodyssee Nouveaux polynucleotides et polypeptides de l'ifn alpha 7
CA2604399A1 (en) 2005-04-11 2006-10-19 Savient Pharmaceuticals, Inc. Variant forms of urate oxidase and use thereof
CN107033233A (zh) * 2008-01-18 2017-08-11 弗·哈夫曼-拉罗切有限公司 非糖基化蛋白质的纯化
SG10201408480RA (en) 2009-06-25 2015-02-27 Crealta Pharmaceuticals Llc Methods for preventing or predicting infusion reactions or antibody-mediated loss of response, by monitoring serum uric acid levels during pegylated uricase therapy
WO2018087345A1 (en) 2016-11-14 2018-05-17 F. Hoffmann-La Roche Ag COMBINATION THERAPY OF AN HBsAg INHIBITOR, A NUCLEOS(T)IDE ANALOGUE AND AN INTERFERON
US12269875B2 (en) 2023-08-03 2025-04-08 Jeff R. Peterson Gout flare prevention methods using IL-1BETA blockers

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IN150740B (en:Method) * 1978-11-24 1982-12-04 Hoffmann La Roche
FI77877C (fi) * 1979-04-20 1989-05-10 Technobiotic Ltd Foerfarande foer framstaellning och rening av human le-formig interferonprotein.
NZ195980A (en) * 1980-01-08 1984-10-19 Biogen Nv Dna sequences,recombinant dna molecules and processes for producing leukocyte interferon-like polypeptides;pharmaceutical and veterinary compositions
DE3005897A1 (de) * 1980-02-16 1981-09-03 Hoechst Ag, 6000 Frankfurt Genprodukt eines hoeheren organismus aus einem dieses gen enhtaltenden mikroorganismus
EP0042246B1 (en) * 1980-06-12 1987-03-18 The Cancer Institute Of Japanese Foundation For Cancer Research Plasmid
ES8302778A1 (es) * 1980-11-10 1983-02-01 Genentech Inc Un procedimiento para producir un polipeptido antiviral.
FI64813C (fi) * 1980-12-31 1984-01-10 Ilkka Antero Palva Foerfarande foer producering av ett utvalt aeggviteaemne och vid foerfarandet anvaenda rekombinantplasmidvektorer
DE3280127D1 (de) * 1981-03-27 1990-04-12 Ici Plc Genetisch modifizierte mikroorganismen.

Also Published As

Publication number Publication date
CH657141A5 (de) 1986-08-15
PT73289B (en) 1983-05-11
DE3176448D1 (en) 1987-10-22
BG42189A3 (en) 1987-10-15
BR8104189A (pt) 1982-03-16
FR2486098B1 (fr) 1985-12-27
IE49255B1 (en) 1985-09-04
YU47700B (sh) 1996-01-08
DE3177288T3 (de) 2000-03-16
CS503781A2 (en) 1990-07-12
CS273152B2 (en) 1991-03-12
FI82712B (fi) 1990-12-31
ES8207514A1 (es) 1982-10-01
GR75714B (en:Method) 1984-08-02
GB2079291B (en) 1984-06-13
YU162281A (en) 1984-02-29
DD210305A5 (de) 1984-06-06
EP0043980A3 (en) 1982-09-15
EP0211148A1 (en) 1987-02-25
DE3177288D1 (de) 1992-10-01
NL8103151A (nl) 1982-02-01
NZ197572A (en) 1985-07-31
CH651308A5 (de) 1985-09-13
LU83461A1 (de) 1983-04-06
ATE29727T1 (de) 1987-10-15
HK49285A (en) 1985-07-05
DE3177288T2 (de) 1992-12-10
EP0043980A2 (en) 1982-01-20
SE465223B (sv) 1991-08-12
ATE79901T1 (de) 1992-09-15
SE8104093L (sv) 1982-01-02
ATA290981A (de) 1985-09-15
EP0043980B1 (en) 1987-09-16
DE3125706C2 (de) 1995-05-24
DD210304A5 (de) 1984-06-06
NO159392C (no) 1988-12-21
AU7246281A (en) 1982-01-07
FR2486098A1 (fr) 1982-01-08
MY8700711A (en) 1987-12-31
PL231940A1 (en) 1983-07-18
HU196457B (en) 1988-11-28
PT73289A (en) 1981-07-01
IE811463L (en) 1982-01-01
AR242833A1 (es) 1993-05-31
KE3534A (en) 1985-06-07
DK291081A (da) 1982-01-02
PL148276B1 (en) 1989-09-30
AT380272B (de) 1986-05-12
PL148261B1 (en) 1989-09-30
DE3125706A1 (de) 1982-04-15
MC1396A1 (fr) 1982-04-27
PL148260B1 (en) 1989-09-30
GB2079291A (en) 1982-01-20
FI82712C (fi) 1991-04-10
IT1137272B (it) 1986-09-03
GEP19960519B (en) 1996-07-02
DZ312A1 (fr) 2004-09-13
EP0211148B1 (en) 1992-08-26
NO159392B (no) 1988-09-12
SU1414319A3 (ru) 1988-07-30
IT8122682A0 (it) 1981-07-01
DD202307A5 (de) 1983-09-07
EP0211148B2 (en) 1999-11-24
AU552004B2 (en) 1986-05-22
DK173543B1 (da) 2001-02-05
NO812247L (no) 1982-01-04
SE465223C5 (sv) 1998-02-10
PH18036A (en) 1985-03-06
ES503528A0 (es) 1982-10-01
FI812067L (fi) 1982-01-02

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