PT2970974T - Composições de irna de componente do complemento c5 e métodos para a sua utilização - Google Patents

Composições de irna de componente do complemento c5 e métodos para a sua utilização

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Publication number
PT2970974T
PT2970974T PT147220180T PT14722018T PT2970974T PT 2970974 T PT2970974 T PT 2970974T PT 147220180 T PT147220180 T PT 147220180T PT 14722018 T PT14722018 T PT 14722018T PT 2970974 T PT2970974 T PT 2970974T
Authority
PT
Portugal
Prior art keywords
methods
complement component
iron compositions
component iron
compositions
Prior art date
Application number
PT147220180T
Other languages
English (en)
Portuguese (pt)
Inventor
Manoharan Muthiah
Bettencourt Brian
Fitzgerald Kevin
Butler James
Borodovsky Anna
Kuchimanchi Satyanarayana
Charisse Klaus
Maier Martin
G Rajeev Kallanthottathil
Foster Donald
Original Assignee
Alnylam Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Alnylam Pharmaceuticals Inc filed Critical Alnylam Pharmaceuticals Inc
Publication of PT2970974T publication Critical patent/PT2970974T/pt

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    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/113Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
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PT147220180T 2013-03-14 2014-03-13 Composições de irna de componente do complemento c5 e métodos para a sua utilização PT2970974T (pt)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201361782531P 2013-03-14 2013-03-14
US201361837399P 2013-06-20 2013-06-20
US201361904579P 2013-11-15 2013-11-15
US201361912777P 2013-12-06 2013-12-06
US201461942367P 2014-02-20 2014-02-20

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PT2970974T true PT2970974T (pt) 2017-11-29

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EP (3) EP3312281A3 (enExample)
JP (5) JP6524060B2 (enExample)
KR (4) KR102605775B1 (enExample)
CN (3) CN120574828A (enExample)
AU (4) AU2014244116B9 (enExample)
BR (1) BR112015022876B1 (enExample)
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DK (1) DK2970974T3 (enExample)
DO (1) DOP2015000234A (enExample)
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MX (2) MX366660B (enExample)
MY (1) MY201504A (enExample)
NZ (1) NZ712336A (enExample)
PE (2) PE20160046A1 (enExample)
PL (1) PL2970974T3 (enExample)
PT (1) PT2970974T (enExample)
RS (1) RS56663B1 (enExample)
SG (3) SG10201912286TA (enExample)
SI (1) SI2970974T1 (enExample)
SM (1) SMT201700552T1 (enExample)
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Families Citing this family (67)

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US9228186B2 (en) 2002-11-14 2016-01-05 Thermo Fisher Scientific Inc. Methods and compositions for selecting siRNA of improved functionality
US9879266B2 (en) 2002-11-14 2018-01-30 Thermo Fisher Scientific Inc. Methods and compositions for selecting siRNA of improved functionality
CN104105790A (zh) 2011-11-18 2014-10-15 阿尔尼拉姆医药品有限公司 修饰的RNAi试剂
SG10201912286TA (en) * 2013-03-14 2020-02-27 Alnylam Pharmaceuticals Inc COMPLEMENT COMPONENT C5 iRNA COMPOSITIONS AND METHODS OF USE THEREOF
US20160051673A1 (en) 2013-03-29 2016-02-25 Alexion Pharmaceuticals, Inc. Compositions and methods for increasing the serum half-life of a therapeutic agent targeting complement c5
CA2943894A1 (en) 2014-05-01 2015-11-05 Ionis Pharmaceuticals, Inc. Compositions and methods for modulating complement factor b expression
IL316808A (en) 2014-08-20 2025-01-01 Alnylam Pharmaceuticals Inc Modified double-stranded RNA materials and their uses
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