BR112015022876B1 - Agente de rna fita dupla, composição farmacêutica e método para inibição da expressão do componente do complemento c5 em uma célula - Google Patents

Agente de rna fita dupla, composição farmacêutica e método para inibição da expressão do componente do complemento c5 em uma célula Download PDF

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BR112015022876B1
BR112015022876B1 BR112015022876-3A BR112015022876A BR112015022876B1 BR 112015022876 B1 BR112015022876 B1 BR 112015022876B1 BR 112015022876 A BR112015022876 A BR 112015022876A BR 112015022876 B1 BR112015022876 B1 BR 112015022876B1
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Prior art keywords
nucleotides
rnai
nucleotide
strand
cell
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BR112015022876-3A
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English (en)
Portuguese (pt)
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BR112015022876A2 (pt
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Kevin Fitzgerald
James Butler
Brian Bettencourt
Anna Borodovsky
Satyanarayana KUCHIMANCHI
Klaus Charisse
Muthiah Manoharan
Martin Maier
Kallanthottathil G. Rajeev
Donald Foster
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Alnylam Pharmaceuticals, Inc
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Publication of BR112015022876A2 publication Critical patent/BR112015022876A2/pt
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BR112015022876-3A 2013-03-14 2014-03-13 Agente de rna fita dupla, composição farmacêutica e método para inibição da expressão do componente do complemento c5 em uma célula BR112015022876B1 (pt)

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US201361782531P 2013-03-14 2013-03-14
US61/782,531 2013-03-14
US201361837399P 2013-06-20 2013-06-20
US61/837,399 2013-06-20
US201361904579P 2013-11-15 2013-11-15
US61/904,579 2013-11-15
US201361912777P 2013-12-06 2013-12-06
US61/912,777 2013-12-06
US201461942367P 2014-02-20 2014-02-20
US61/942,367 2014-02-20
PCT/US2014/025882 WO2014160129A2 (en) 2013-03-14 2014-03-13 Complement component c5 irna compositions and methods of use thereof

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BR112015022876A2 BR112015022876A2 (pt) 2017-11-07
BR112015022876B1 true BR112015022876B1 (pt) 2022-03-15

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