RS56663B1 - Irnk sastavi komponente komplementa c5 i metode za njihovu upotrebu - Google Patents
Irnk sastavi komponente komplementa c5 i metode za njihovu upotrebuInfo
- Publication number
- RS56663B1 RS56663B1 RS20171204A RSP20171204A RS56663B1 RS 56663 B1 RS56663 B1 RS 56663B1 RS 20171204 A RS20171204 A RS 20171204A RS P20171204 A RSP20171204 A RS P20171204A RS 56663 B1 RS56663 B1 RS 56663B1
- Authority
- RS
- Serbia
- Prior art keywords
- methods
- complement component
- irna compositions
- irna
- compositions
- Prior art date
Links
- 230000000295 complement effect Effects 0.000 title 1
- 239000000203 mixture Substances 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
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- A61K31/7088—Compounds having three or more nucleosides or nucleotides
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- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39533—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals
- A61K39/3955—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum against materials from animals against proteinaceous materials, e.g. enzymes, hormones, lymphokines
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- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/76—Antagonist effect on antigen, e.g. neutralization or inhibition of binding
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- C12N2310/14—Type of nucleic acid interfering N.A.
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- C12N2310/31—Chemical structure of the backbone
- C12N2310/312—Phosphonates
- C12N2310/3125—Methylphosphonates
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- C12N2310/315—Phosphorothioates
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- C12N2310/32—Chemical structure of the sugar
- C12N2310/321—2'-O-R Modification
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- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Genetics & Genomics (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Diabetes (AREA)
- Immunology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biochemistry (AREA)
- Cardiology (AREA)
- Neurology (AREA)
- Hematology (AREA)
- Heart & Thoracic Surgery (AREA)
- Epidemiology (AREA)
- Endocrinology (AREA)
- Urology & Nephrology (AREA)
- Microbiology (AREA)
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Applications Claiming Priority (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201361782531P | 2013-03-14 | 2013-03-14 | |
US201361837399P | 2013-06-20 | 2013-06-20 | |
US201361904579P | 2013-11-15 | 2013-11-15 | |
US201361912777P | 2013-12-06 | 2013-12-06 | |
US201461942367P | 2014-02-20 | 2014-02-20 | |
EP14722018.0A EP2970974B1 (en) | 2013-03-14 | 2014-03-13 | Complement component c5 irna compositions and methods of use thereof |
PCT/US2014/025882 WO2014160129A2 (en) | 2013-03-14 | 2014-03-13 | Complement component c5 irna compositions and methods of use thereof |
Publications (1)
Publication Number | Publication Date |
---|---|
RS56663B1 true RS56663B1 (sr) | 2018-03-30 |
Family
ID=50678278
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
RS20171204A RS56663B1 (sr) | 2013-03-14 | 2014-03-13 | Irnk sastavi komponente komplementa c5 i metode za njihovu upotrebu |
Country Status (33)
Country | Link |
---|---|
US (6) | US9249415B2 (sr) |
EP (2) | EP3312281A3 (sr) |
JP (4) | JP6524060B2 (sr) |
KR (4) | KR102234620B1 (sr) |
CN (2) | CN114015692A (sr) |
AU (3) | AU2014244116B9 (sr) |
BR (1) | BR112015022876B1 (sr) |
CA (2) | CA3216595A1 (sr) |
CL (4) | CL2015002710A1 (sr) |
CR (1) | CR20150493A (sr) |
CY (1) | CY1120289T1 (sr) |
DK (1) | DK2970974T3 (sr) |
DO (1) | DOP2015000234A (sr) |
EA (1) | EA201591707A1 (sr) |
ES (1) | ES2649490T3 (sr) |
GT (1) | GT201500293A (sr) |
HK (2) | HK1221484A1 (sr) |
HR (1) | HRP20171813T1 (sr) |
HU (1) | HUE034987T2 (sr) |
IL (2) | IL265594B (sr) |
LT (1) | LT2970974T (sr) |
ME (1) | ME03043B (sr) |
MX (2) | MX366660B (sr) |
NZ (1) | NZ712336A (sr) |
PE (2) | PE20211393A1 (sr) |
PL (1) | PL2970974T3 (sr) |
PT (1) | PT2970974T (sr) |
RS (1) | RS56663B1 (sr) |
SG (3) | SG11201507400SA (sr) |
SI (1) | SI2970974T1 (sr) |
TW (4) | TWI808369B (sr) |
UY (2) | UY35442A (sr) |
WO (1) | WO2014160129A2 (sr) |
Families Citing this family (58)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9879266B2 (en) | 2002-11-14 | 2018-01-30 | Thermo Fisher Scientific Inc. | Methods and compositions for selecting siRNA of improved functionality |
US9228186B2 (en) | 2002-11-14 | 2016-01-05 | Thermo Fisher Scientific Inc. | Methods and compositions for selecting siRNA of improved functionality |
MX359548B (es) | 2011-11-18 | 2018-10-02 | Alnylam Pharmaceuticals Inc | Agentes de iarn modificados. |
PL2970974T3 (pl) | 2013-03-14 | 2018-01-31 | Alnylam Pharmaceuticals Inc | Kompozycje komponentu C5 dopełniacza iRNA i sposoby ich zastosowania |
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