PL205127B1 - Wodna biodegradowalna polimerowa kompozycja dostarczania leków i sposób zwiększania rozpuszczalności leku - Google Patents
Wodna biodegradowalna polimerowa kompozycja dostarczania leków i sposób zwiększania rozpuszczalności lekuInfo
- Publication number
- PL205127B1 PL205127B1 PL346963A PL34696399A PL205127B1 PL 205127 B1 PL205127 B1 PL 205127B1 PL 346963 A PL346963 A PL 346963A PL 34696399 A PL34696399 A PL 34696399A PL 205127 B1 PL205127 B1 PL 205127B1
- Authority
- PL
- Poland
- Prior art keywords
- polymer
- lactide
- composition
- drug
- lactic acid
- Prior art date
Links
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- 238000011287 therapeutic dose Methods 0.000 description 1
- KSBAEPSJVUENNK-UHFFFAOYSA-L tin(ii) 2-ethylhexanoate Chemical compound [Sn+2].CCCCC(CC)C([O-])=O.CCCCC(CC)C([O-])=O KSBAEPSJVUENNK-UHFFFAOYSA-L 0.000 description 1
- 230000002110 toxicologic effect Effects 0.000 description 1
- 231100000027 toxicology Toxicity 0.000 description 1
- 238000005809 transesterification reaction Methods 0.000 description 1
- 230000009466 transformation Effects 0.000 description 1
- 230000008733 trauma Effects 0.000 description 1
- 238000011269 treatment regimen Methods 0.000 description 1
- 238000000825 ultraviolet detection Methods 0.000 description 1
- 239000003981 vehicle Substances 0.000 description 1
- 239000004520 water soluble gel Substances 0.000 description 1
- 229920003169 water-soluble polymer Polymers 0.000 description 1
- 229960000607 ziprasidone Drugs 0.000 description 1
- MVWVFYHBGMAFLY-UHFFFAOYSA-N ziprasidone Chemical compound C1=CC=C2C(N3CCN(CC3)CCC3=CC=4CC(=O)NC=4C=C3Cl)=NSC2=C1 MVWVFYHBGMAFLY-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
- C08G63/91—Polymers modified by chemical after-treatment
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
- C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
- C08G63/66—Polyesters containing oxygen in the form of ether groups
- C08G63/664—Polyesters containing oxygen in the form of ether groups derived from hydroxy carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
- A61K9/0024—Solid, semi-solid or solidifying implants, which are implanted or injected in body tissue
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
- A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
- A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
- C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
- C08L71/00—Compositions of polyethers obtained by reactions forming an ether link in the main chain; Compositions of derivatives of such polymers
- C08L71/02—Polyalkylene oxides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Polymers & Plastics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Dermatology (AREA)
- Inorganic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Dispersion Chemistry (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Preparation (AREA)
- Biological Depolymerization Polymers (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Polyesters Or Polycarbonates (AREA)
- Compositions Of Macromolecular Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/164,865 US6117949A (en) | 1998-10-01 | 1998-10-01 | Biodegradable low molecular weight triblock poly (lactide-co-glycolide) polyethylene glycol copolymers having reverse thermal gelation properties |
| US09/396,589 US6201072B1 (en) | 1997-10-03 | 1999-09-15 | Biodegradable low molecular weight triblock poly(lactide-co- glycolide) polyethylene glycol copolymers having reverse thermal gelation properties |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PL346963A1 PL346963A1 (en) | 2002-03-11 |
| PL205127B1 true PL205127B1 (pl) | 2010-03-31 |
Family
ID=26860925
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL346963A PL205127B1 (pl) | 1998-10-01 | 1999-09-30 | Wodna biodegradowalna polimerowa kompozycja dostarczania leków i sposób zwiększania rozpuszczalności leku |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US6201072B1 (OSRAM) |
| EP (1) | EP1141079B1 (OSRAM) |
| JP (1) | JP4628545B2 (OSRAM) |
| KR (1) | KR100558025B1 (OSRAM) |
| CN (1) | CN1161396C (OSRAM) |
| AT (1) | ATE378365T1 (OSRAM) |
| AU (1) | AU758475B2 (OSRAM) |
| BR (1) | BR9914258B1 (OSRAM) |
| CA (1) | CA2345659C (OSRAM) |
| CY (1) | CY1107888T1 (OSRAM) |
| DK (1) | DK1141079T3 (OSRAM) |
| ES (1) | ES2301250T3 (OSRAM) |
| IL (1) | IL142313A0 (OSRAM) |
| NO (1) | NO332941B1 (OSRAM) |
| NZ (1) | NZ510832A (OSRAM) |
| PL (1) | PL205127B1 (OSRAM) |
| RU (1) | RU2232779C2 (OSRAM) |
| TR (1) | TR200100900T2 (OSRAM) |
| WO (1) | WO2000018821A1 (OSRAM) |
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-
1999
- 1999-09-15 US US09/396,589 patent/US6201072B1/en not_active Expired - Lifetime
- 1999-09-30 IL IL14231399A patent/IL142313A0/xx unknown
- 1999-09-30 EP EP99954698A patent/EP1141079B1/en not_active Expired - Lifetime
- 1999-09-30 DK DK99954698T patent/DK1141079T3/da active
- 1999-09-30 RU RU2001111856/04A patent/RU2232779C2/ru not_active IP Right Cessation
- 1999-09-30 WO PCT/US1999/022755 patent/WO2000018821A1/en not_active Ceased
- 1999-09-30 KR KR1020017004062A patent/KR100558025B1/ko not_active Expired - Fee Related
- 1999-09-30 CA CA2345659A patent/CA2345659C/en not_active Expired - Fee Related
- 1999-09-30 AT AT99954698T patent/ATE378365T1/de active
- 1999-09-30 JP JP2000572276A patent/JP4628545B2/ja not_active Expired - Fee Related
- 1999-09-30 PL PL346963A patent/PL205127B1/pl unknown
- 1999-09-30 BR BRPI9914258-9A patent/BR9914258B1/pt not_active IP Right Cessation
- 1999-09-30 AU AU10983/00A patent/AU758475B2/en not_active Ceased
- 1999-09-30 CN CNB998124958A patent/CN1161396C/zh not_active Expired - Fee Related
- 1999-09-30 TR TR2001/00900T patent/TR200100900T2/xx unknown
- 1999-09-30 NZ NZ510832A patent/NZ510832A/xx not_active IP Right Cessation
- 1999-09-30 ES ES99954698T patent/ES2301250T3/es not_active Expired - Lifetime
-
2001
- 2001-03-30 NO NO20011639A patent/NO332941B1/no not_active IP Right Cessation
-
2008
- 2008-02-14 CY CY20081100186T patent/CY1107888T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA2345659A1 (en) | 2000-04-06 |
| CN1324374A (zh) | 2001-11-28 |
| JP2002525404A (ja) | 2002-08-13 |
| DK1141079T3 (da) | 2008-03-25 |
| AU1098300A (en) | 2000-04-17 |
| PL346963A1 (en) | 2002-03-11 |
| BR9914258A (pt) | 2001-07-03 |
| ATE378365T1 (de) | 2007-11-15 |
| CA2345659C (en) | 2010-09-21 |
| NO332941B1 (no) | 2013-02-04 |
| KR100558025B1 (ko) | 2006-03-07 |
| CN1161396C (zh) | 2004-08-11 |
| NO20011639L (no) | 2001-03-30 |
| WO2000018821A1 (en) | 2000-04-06 |
| CY1107888T1 (el) | 2013-06-19 |
| US6201072B1 (en) | 2001-03-13 |
| EP1141079B1 (en) | 2007-11-14 |
| BR9914258B1 (pt) | 2014-07-15 |
| JP4628545B2 (ja) | 2011-02-09 |
| RU2232779C2 (ru) | 2004-07-20 |
| NZ510832A (en) | 2002-10-25 |
| IL142313A0 (en) | 2002-03-10 |
| KR20010083880A (ko) | 2001-09-03 |
| ES2301250T3 (es) | 2008-06-16 |
| AU758475B2 (en) | 2003-03-20 |
| EP1141079A1 (en) | 2001-10-10 |
| NO20011639D0 (no) | 2001-03-30 |
| TR200100900T2 (tr) | 2001-10-22 |
| EP1141079A4 (en) | 2004-03-24 |
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