PL198151B1 - Pochodne izotiazolu, środek farmaceutyczny zastosowanie pochodnych izotiazolu, sposób wytwarzania pochodnych izotiazolu i związki pośrednie - Google Patents

Pochodne izotiazolu, środek farmaceutyczny zastosowanie pochodnych izotiazolu, sposób wytwarzania pochodnych izotiazolu i związki pośrednie

Info

Publication number
PL198151B1
PL198151B1 PL344691A PL34469199A PL198151B1 PL 198151 B1 PL198151 B1 PL 198151B1 PL 344691 A PL344691 A PL 344691A PL 34469199 A PL34469199 A PL 34469199A PL 198151 B1 PL198151 B1 PL 198151B1
Authority
PL
Poland
Prior art keywords
alkyl
isothiazole
methylbenzyloxy
carboxylic acid
ureido
Prior art date
Application number
PL344691A
Other languages
English (en)
Polish (pl)
Other versions
PL344691A1 (en
Inventor
Eric Robert Larson
Mark Carl Noe
Thomas George Gant
Original Assignee
Pfizer Prod Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Prod Inc filed Critical Pfizer Prod Inc
Publication of PL344691A1 publication Critical patent/PL344691A1/xx
Publication of PL198151B1 publication Critical patent/PL198151B1/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D275/00Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings
    • C07D275/02Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings not condensed with other rings
    • C07D275/03Heterocyclic compounds containing 1,2-thiazole or hydrogenated 1,2-thiazole rings not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/08Drugs for disorders of the urinary system of the prostate
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C327/00Thiocarboxylic acids
    • C07C327/58Derivatives of thiocarboxylic acids, the doubly-bound oxygen atoms being replaced by nitrogen atoms, e.g. imino-thio ethers
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C33/00Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
    • C07C33/40Halogenated unsaturated alcohols
    • C07C33/46Halogenated unsaturated alcohols containing only six-membered aromatic rings as cyclic parts
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D231/00Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D249/00Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/081,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08Bridged systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
PL344691A 1998-06-04 1999-05-03 Pochodne izotiazolu, środek farmaceutyczny zastosowanie pochodnych izotiazolu, sposób wytwarzania pochodnych izotiazolu i związki pośrednie PL198151B1 (pl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US8796398P 1998-06-04 1998-06-04
PCT/IB1999/000797 WO1999062890A1 (en) 1998-06-04 1999-05-03 Isothiazole derivatives useful as anticancer agents

Publications (2)

Publication Number Publication Date
PL344691A1 PL344691A1 (en) 2001-11-19
PL198151B1 true PL198151B1 (pl) 2008-05-30

Family

ID=22208298

Family Applications (1)

Application Number Title Priority Date Filing Date
PL344691A PL198151B1 (pl) 1998-06-04 1999-05-03 Pochodne izotiazolu, środek farmaceutyczny zastosowanie pochodnych izotiazolu, sposób wytwarzania pochodnych izotiazolu i związki pośrednie

Country Status (45)

Country Link
US (4) US6235764B1 (OSRAM)
EP (1) EP1084114B1 (OSRAM)
JP (2) JP3735254B2 (OSRAM)
KR (1) KR100392434B1 (OSRAM)
CN (2) CN1616386A (OSRAM)
AP (1) AP1309A (OSRAM)
AR (1) AR016725A1 (OSRAM)
AT (1) ATE275553T1 (OSRAM)
AU (1) AU3342199A (OSRAM)
BG (1) BG65104B1 (OSRAM)
BR (1) BR9910900B1 (OSRAM)
CA (2) CA2333703C (OSRAM)
CO (1) CO5011121A1 (OSRAM)
CZ (1) CZ298559B6 (OSRAM)
DE (1) DE69920009T2 (OSRAM)
EA (1) EA004935B1 (OSRAM)
ES (1) ES2226368T3 (OSRAM)
GE (1) GEP20084337B (OSRAM)
GT (1) GT199900070A (OSRAM)
HN (1) HN1999000080A (OSRAM)
HR (1) HRP20000835B1 (OSRAM)
HU (1) HUP0102422A3 (OSRAM)
ID (1) ID27006A (OSRAM)
IL (1) IL138776A0 (OSRAM)
IS (1) IS2269B (OSRAM)
MA (1) MA26638A1 (OSRAM)
MY (1) MY130668A (OSRAM)
NO (1) NO318798B1 (OSRAM)
NZ (1) NZ507009A (OSRAM)
OA (1) OA11504A (OSRAM)
PA (1) PA8472301A1 (OSRAM)
PE (1) PE20000568A1 (OSRAM)
PL (1) PL198151B1 (OSRAM)
PT (1) PT1084114E (OSRAM)
SA (1) SA99200217B1 (OSRAM)
SI (1) SI1084114T1 (OSRAM)
SK (1) SK286405B6 (OSRAM)
TN (1) TNSN99106A1 (OSRAM)
TR (1) TR200003478T2 (OSRAM)
TW (1) TW561154B (OSRAM)
UA (1) UA60365C2 (OSRAM)
UY (1) UY25619A1 (OSRAM)
WO (1) WO1999062890A1 (OSRAM)
YU (1) YU70100A (OSRAM)
ZA (1) ZA993752B (OSRAM)

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CN1616386A (zh) 2005-05-18
NO20006071D0 (no) 2000-11-30
SI1084114T1 (en) 2005-02-28
CA2475113C (en) 2008-03-18
SA99200217B1 (ar) 2006-05-06
CZ20004451A3 (en) 2001-05-16
BR9910900A (pt) 2001-02-13
JP2005002122A (ja) 2005-01-06
IS2269B (is) 2007-07-15
HRP20000835A2 (en) 2001-12-31
HN1999000080A (es) 1999-09-29
MA26638A1 (fr) 2004-12-20
CN1172918C (zh) 2004-10-27
CA2333703C (en) 2005-06-14
EP1084114A1 (en) 2001-03-21
IL138776A0 (en) 2001-10-31
OA11504A (en) 2004-05-17
NO318798B1 (no) 2005-05-09
PA8472301A1 (es) 2000-09-29
DE69920009T2 (de) 2005-09-15
KR100392434B1 (ko) 2003-07-22
HUP0102422A3 (en) 2002-06-28

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