PL191251B1 - Sposób wprowadzania żądanego DNA w docelowe miejsce w genomie ssaka i układ wektorów - Google Patents
Sposób wprowadzania żądanego DNA w docelowe miejsce w genomie ssaka i układ wektorówInfo
- Publication number
- PL191251B1 PL191251B1 PL335695A PL33569598A PL191251B1 PL 191251 B1 PL191251 B1 PL 191251B1 PL 335695 A PL335695 A PL 335695A PL 33569598 A PL33569598 A PL 33569598A PL 191251 B1 PL191251 B1 PL 191251B1
- Authority
- PL
- Poland
- Prior art keywords
- dna
- plasmid
- protein
- marker
- tag
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2851—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the lectin superfamily, e.g. CD23, CD72
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/70521—CD28, CD152
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2896—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against molecules with a "CD"-designation, not provided for elsewhere
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
- C12N15/90—Stable introduction of foreign DNA into chromosome
- C12N15/902—Stable introduction of foreign DNA into chromosome using homologous recombination
- C12N15/907—Stable introduction of foreign DNA into chromosome using homologous recombination in mammalian cells
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
- C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2800/00—Nucleic acids vectors
- C12N2800/10—Plasmid DNA
- C12N2800/108—Plasmid DNA episomal vectors
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2830/00—Vector systems having a special element relevant for transcription
- C12N2830/42—Vector systems having a special element relevant for transcription being an intron or intervening sequence for splicing and/or stability of RNA
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2840/00—Vectors comprising a special translation-regulating system
- C12N2840/20—Vectors comprising a special translation-regulating system translation of more than one cistron
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2840/00—Vectors comprising a special translation-regulating system
- C12N2840/44—Vectors comprising a special translation-regulating system being a specific part of the splice mechanism, e.g. donor, acceptor
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Wood Science & Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Microbiology (AREA)
- Cell Biology (AREA)
- Toxicology (AREA)
- Gastroenterology & Hepatology (AREA)
- Mycology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/819,866 US5830698A (en) | 1997-03-14 | 1997-03-14 | Method for integrating genes at specific sites in mammalian cells via homologous recombination and vectors for accomplishing the same |
| US09/023,715 US5998144A (en) | 1997-03-14 | 1998-02-13 | Method for integrating genes at specific sites in mammalian cells via homologous recombination and vectors for accomplishing the same |
| PCT/US1998/003935 WO1998041645A1 (en) | 1997-03-14 | 1998-03-09 | Method for integrating genes at specific sites in mammalian cells via homologous recombination and vectors for accomplishing the same |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| PL335695A1 PL335695A1 (en) | 2000-05-08 |
| PL191251B1 true PL191251B1 (pl) | 2006-04-28 |
Family
ID=26697516
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PL335695A PL191251B1 (pl) | 1997-03-14 | 1998-03-09 | Sposób wprowadzania żądanego DNA w docelowe miejsce w genomie ssaka i układ wektorów |
Country Status (21)
| Country | Link |
|---|---|
| US (3) | US6413777B1 (https=) |
| EP (1) | EP0981637B1 (https=) |
| JP (1) | JP4128227B2 (https=) |
| CN (1) | CN1175111C (https=) |
| AT (1) | ATE296356T1 (https=) |
| AU (1) | AU737155B2 (https=) |
| BR (1) | BR9808584A (https=) |
| CA (1) | CA2283740C (https=) |
| CZ (1) | CZ293355B6 (https=) |
| DE (1) | DE69830312T2 (https=) |
| ES (1) | ES2242997T3 (https=) |
| ID (1) | ID24565A (https=) |
| IL (1) | IL131746A0 (https=) |
| IN (1) | IN189732B (https=) |
| NO (1) | NO994397L (https=) |
| PL (1) | PL191251B1 (https=) |
| PT (1) | PT981637E (https=) |
| RO (1) | RO120148B1 (https=) |
| RU (1) | RU2004107694A (https=) |
| TW (1) | TWI232239B (https=) |
| WO (1) | WO1998041645A1 (https=) |
Families Citing this family (109)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5830698A (en) * | 1997-03-14 | 1998-11-03 | Idec Pharmaceuticals Corporation | Method for integrating genes at specific sites in mammalian cells via homologous recombination and vectors for accomplishing the same |
| AU737155B2 (en) * | 1997-03-14 | 2001-08-09 | Biogen Idec Inc. | Method for integrating genes at specific sites in mammalian cells via homologous recombination and vectors for accomplishing the same |
| US6537746B2 (en) | 1997-12-08 | 2003-03-25 | Maxygen, Inc. | Method for creating polynucleotide and polypeptide sequences |
| AU2221600A (en) | 1998-12-31 | 2000-07-31 | Chiron Corporation | Improved expression of hiv polypeptides and production of virus-like particles |
| AU2487300A (en) | 1998-12-31 | 2000-07-31 | Chiron Corporation | Polynucleotides encoding antigenic hiv type c polypeptides, polypeptides and uses thereof |
| GB9912965D0 (en) * | 1999-06-03 | 1999-08-04 | Oxford Biomedica Ltd | In vivo selection method |
| US6316253B1 (en) | 1999-11-01 | 2001-11-13 | Chiron Corporation | Expression vectors, transfection systems, and method of use thereof |
| CN1322138C (zh) * | 2000-06-23 | 2007-06-20 | 诺维信公司 | 用于基因的稳定的染色体多拷贝整合的方法 |
| EP1411770A4 (en) | 2001-07-05 | 2006-05-10 | Chiron Corp | POLYNUCLEOTIDES CODING FOR ANTIGENIC C-TYPE HIV POLYPEPTIDES, POLYPEPTIDES AND THEIR USE |
| US20030170614A1 (en) | 2001-08-31 | 2003-09-11 | Megede Jan Zur | Polynucleotides encoding antigenic HIV type B polypeptides, polypeptides and uses thereof |
| MXPA04004634A (es) | 2001-11-16 | 2004-08-12 | Idec Pharma Corp | Expresion policistronica de anticuerpos. |
| US7164056B2 (en) * | 2002-05-03 | 2007-01-16 | Pioneer Hi-Bred International, Inc. | Gene targeting using replicating DNA molecules |
| DK2314629T4 (da) | 2002-07-18 | 2023-02-06 | Merus Nv | Rekombinant produktion af blandinger af antistoffer |
| USRE47770E1 (en) | 2002-07-18 | 2019-12-17 | Merus N.V. | Recombinant production of mixtures of antibodies |
| US20040170614A1 (en) * | 2002-10-30 | 2004-09-02 | Gail Bishop | Somatic cell gene targeting vectors and methods of use thereof |
| SI1583830T1 (sl) * | 2003-01-07 | 2006-12-31 | Symphogen As | Postopek za pripravo rekombinantnih poliklonskih proteinov |
| DE10303937A1 (de) * | 2003-01-31 | 2004-08-12 | Icon Genetics Ag | Pflanzentransformation mit Assemblierung einer gewünschten Sequenz in Vivo |
| EP1587932B1 (en) * | 2003-01-31 | 2009-03-25 | Icon Genetics GmbH | Plant transformation with in vivo assembly of a trait |
| CA2519227C (en) | 2003-03-19 | 2013-12-03 | Biogen Idec Ma Inc. | Nogo receptor binding protein |
| TWI353991B (en) | 2003-05-06 | 2011-12-11 | Syntonix Pharmaceuticals Inc | Immunoglobulin chimeric monomer-dimer hybrids |
| CN1802388B (zh) * | 2003-05-09 | 2011-01-05 | 杜克大学 | Cd20特异抗体及使用它们的方法 |
| US20100069614A1 (en) | 2008-06-27 | 2010-03-18 | Merus B.V. | Antibody producing non-human mammals |
| WO2004106375A1 (en) | 2003-05-30 | 2004-12-09 | Merus Biopharmaceuticals B.V. I.O. | Fab library for the preparation of anti vegf and anti rabies virus fabs |
| NZ544924A (en) * | 2003-06-27 | 2009-03-31 | Biogen Idec Inc | Modified binding molecules comprising connecting peptides |
| JP4751326B2 (ja) | 2003-09-04 | 2011-08-17 | メダレックス インコーポレイテッド | 発現ベクター |
| US7344753B2 (en) * | 2003-09-19 | 2008-03-18 | The Board Of Trustees Of The University Of Illinois | Nanostructures including a metal |
| US8030833B2 (en) * | 2003-09-19 | 2011-10-04 | The Board Of Trustees Of The University Of Illinois | Electron emission device incorporating free standing monocrystalline nanowires |
| US7935862B2 (en) * | 2003-12-02 | 2011-05-03 | Syngenta Participations Ag | Targeted integration and stacking of DNA through homologous recombination |
| EP1737971B1 (en) | 2004-01-20 | 2017-08-16 | Merus N.V. | Mixtures of binding proteins |
| US8486893B2 (en) | 2004-06-24 | 2013-07-16 | Biogen Idec Ma Inc. | Treatment of conditions involving demyelination |
| US8288109B2 (en) | 2004-07-20 | 2012-10-16 | Symphogen A/S | Procedure for structural characterization of a recombinant polyclonal protein or a polyclonal cell line |
| EP1789070B1 (en) | 2004-08-03 | 2012-10-24 | Biogen Idec MA Inc. | Taj in neuronal function |
| FR2879204B1 (fr) * | 2004-12-15 | 2007-02-16 | Lab Francais Du Fractionnement | Anticorps cytotoxique dirige contre les proliferations hematopoietiques lymphoides de type b. |
| EP1838736B1 (en) | 2005-01-05 | 2013-03-06 | Biogen Idec MA Inc. | Cripto binding molecules |
| CN100381573C (zh) * | 2005-04-14 | 2008-04-16 | 北京天广实生物技术有限公司 | 快速构建目标基因高表达的哺乳动物细胞株的体系和方法 |
| HRP20131066T1 (hr) | 2005-07-08 | 2013-12-06 | Biogen Idec Ma Inc. | Sp35 antitijela i njihova upotreba |
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| KR20220097891A (ko) | 2019-09-30 | 2022-07-08 | 바이오버라티브 테라퓨틱스 인크. | 렌티바이러스 벡터 제형 |
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| US5202238A (en) * | 1987-10-27 | 1993-04-13 | Oncogen | Production of chimeric antibodies by homologous recombination |
| FR2646438B1 (fr) | 1989-03-20 | 2007-11-02 | Pasteur Institut | Procede de remplacement specifique d'une copie d'un gene present dans le genome receveur par l'integration d'un gene different de celui ou se fait l'integration |
| US5464764A (en) * | 1989-08-22 | 1995-11-07 | University Of Utah Research Foundation | Positive-negative selection methods and vectors |
| EP0945515A3 (en) | 1989-11-06 | 2002-08-21 | Cell Genesys, Inc. | Production of proteins using homologous recombination |
| PT101031B (pt) | 1991-11-05 | 2002-07-31 | Transkaryotic Therapies Inc | Processo para o fornecimento de proteinas por terapia genetica |
| AU4401993A (en) * | 1992-06-04 | 1993-12-30 | Exemplar Corporation | Insertion of heterologous dna outside of known chromosomal genes |
| MX9305183A (es) * | 1992-08-27 | 1994-05-31 | Us Agriculture | Intron portatil, molecula de adn genomico viral, virus vivo y vacuna que los contiene y metodo para su obtencion. |
| US5648267A (en) * | 1992-11-13 | 1997-07-15 | Idec Pharmaceuticals Corporation | Impaired dominant selectable marker sequence and intronic insertion strategies for enhancement of expression of gene product and expression vector systems comprising same |
| AU737155B2 (en) * | 1997-03-14 | 2001-08-09 | Biogen Idec Inc. | Method for integrating genes at specific sites in mammalian cells via homologous recombination and vectors for accomplishing the same |
| US5830698A (en) * | 1997-03-14 | 1998-11-03 | Idec Pharmaceuticals Corporation | Method for integrating genes at specific sites in mammalian cells via homologous recombination and vectors for accomplishing the same |
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1998
- 1998-03-09 AU AU64435/98A patent/AU737155B2/en not_active Ceased
- 1998-03-09 JP JP54053998A patent/JP4128227B2/ja not_active Expired - Fee Related
- 1998-03-09 PT PT98910109T patent/PT981637E/pt unknown
- 1998-03-09 ID IDW991196A patent/ID24565A/id unknown
- 1998-03-09 ES ES98910109T patent/ES2242997T3/es not_active Expired - Lifetime
- 1998-03-09 AT AT98910109T patent/ATE296356T1/de not_active IP Right Cessation
- 1998-03-09 RO RO99-00972A patent/RO120148B1/ro unknown
- 1998-03-09 CZ CZ19993162A patent/CZ293355B6/cs not_active IP Right Cessation
- 1998-03-09 IL IL13174698A patent/IL131746A0/xx not_active IP Right Cessation
- 1998-03-09 CN CNB988049880A patent/CN1175111C/zh not_active Expired - Fee Related
- 1998-03-09 DE DE69830312T patent/DE69830312T2/de not_active Revoked
- 1998-03-09 WO PCT/US1998/003935 patent/WO1998041645A1/en not_active Ceased
- 1998-03-09 EP EP98910109A patent/EP0981637B1/en not_active Revoked
- 1998-03-09 CA CA002283740A patent/CA2283740C/en not_active Expired - Fee Related
- 1998-03-09 BR BR9808584-0A patent/BR9808584A/pt not_active Application Discontinuation
- 1998-03-09 PL PL335695A patent/PL191251B1/pl not_active IP Right Cessation
- 1998-03-10 IN IN616DE1998 patent/IN189732B/en unknown
- 1998-03-13 TW TW087103778A patent/TWI232239B/zh not_active IP Right Cessation
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1999
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- 1999-09-10 NO NO994397A patent/NO994397L/no not_active Application Discontinuation
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2002
- 2002-04-01 US US10/109,853 patent/US6841383B2/en not_active Expired - Fee Related
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2004
- 2004-03-15 RU RU2004107694/13A patent/RU2004107694A/ru not_active Application Discontinuation
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|---|---|
| ES2242997T3 (es) | 2005-11-16 |
| WO1998041645A1 (en) | 1998-09-24 |
| ID24565A (id) | 2000-07-27 |
| NO994397L (no) | 1999-11-09 |
| US6841383B2 (en) | 2005-01-11 |
| CA2283740C (en) | 2006-06-27 |
| ATE296356T1 (de) | 2005-06-15 |
| EP0981637A1 (en) | 2000-03-01 |
| CN1255166A (zh) | 2000-05-31 |
| TWI232239B (en) | 2005-05-11 |
| RO120148B1 (ro) | 2005-09-30 |
| DE69830312T2 (de) | 2006-02-02 |
| US6413777B1 (en) | 2002-07-02 |
| IL131746A0 (en) | 2001-03-19 |
| NO994397D0 (no) | 1999-09-10 |
| JP2001516221A (ja) | 2001-09-25 |
| EP0981637B1 (en) | 2005-05-25 |
| RU2004107694A (ru) | 2005-08-27 |
| BR9808584A (pt) | 2000-05-23 |
| IN189732B (https=) | 2003-04-19 |
| US7235360B2 (en) | 2007-06-26 |
| CN1175111C (zh) | 2004-11-10 |
| CZ316299A3 (cs) | 2000-02-16 |
| AU737155B2 (en) | 2001-08-09 |
| AU6443598A (en) | 1998-10-12 |
| PT981637E (pt) | 2005-09-30 |
| US20020192820A1 (en) | 2002-12-19 |
| CZ293355B6 (cs) | 2004-04-14 |
| US20040166528A1 (en) | 2004-08-26 |
| PL335695A1 (en) | 2000-05-08 |
| CA2283740A1 (en) | 1998-09-24 |
| DE69830312D1 (de) | 2005-06-30 |
| JP4128227B2 (ja) | 2008-07-30 |
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