PE20180042A1 - Anticuerpos anti-ox40 y metodos de uso de los mismos - Google Patents
Anticuerpos anti-ox40 y metodos de uso de los mismosInfo
- Publication number
- PE20180042A1 PE20180042A1 PE2017002714A PE2017002714A PE20180042A1 PE 20180042 A1 PE20180042 A1 PE 20180042A1 PE 2017002714 A PE2017002714 A PE 2017002714A PE 2017002714 A PE2017002714 A PE 2017002714A PE 20180042 A1 PE20180042 A1 PE 20180042A1
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- Prior art keywords
- seq
- heavy chain
- light chain
- antibodies
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/2878—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/50—Immunoglobulins specific features characterized by immunoglobulin fragments
- C07K2317/56—Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
- C07K2317/565—Complementarity determining region [CDR]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/74—Inducing cell proliferation
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/70—Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
- C07K2317/75—Agonist effect on antigen
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Epidemiology (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
Referida a un anticuerpo aislado que se adhiere a OX40 y que comprende una CDR1 de cadena pesada de SEQ ID N°:13, una CDR2 de cadena pesada de SEQ ID N°:14, una CDR3 de cadena pesada de SEQ ID N°:15, una CDR1 de cadena liviana de SEQ ID N°:19, una CDR2 de cadena liviana de SEQ ID N°:20, una CDR3 de cadena liviana de SEQ ID N°:21. Tambien esta referida a acidos nucleicos, vectores y celulas huespedes para expresar los anticuerpos humanos recombinantes
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US37599910P | 2010-08-23 | 2010-08-23 | |
US38082710P | 2010-09-08 | 2010-09-08 |
Publications (1)
Publication Number | Publication Date |
---|---|
PE20180042A1 true PE20180042A1 (es) | 2018-01-09 |
Family
ID=45724011
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PE2013000332A PE20131403A1 (es) | 2010-08-23 | 2011-08-23 | Anticuerpos anti-ox40 y metodos de uso de los mismos |
PE2017002714A PE20180042A1 (es) | 2010-08-23 | 2011-08-23 | Anticuerpos anti-ox40 y metodos de uso de los mismos |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PE2013000332A PE20131403A1 (es) | 2010-08-23 | 2011-08-23 | Anticuerpos anti-ox40 y metodos de uso de los mismos |
Country Status (34)
Country | Link |
---|---|
US (6) | US9006399B2 (es) |
EP (2) | EP2609118B1 (es) |
JP (2) | JP5984810B2 (es) |
KR (2) | KR101719118B1 (es) |
CN (2) | CN103221427B (es) |
AP (1) | AP2013006771A0 (es) |
AU (1) | AU2011293558B2 (es) |
BR (2) | BR112013004266A8 (es) |
CA (1) | CA2809089C (es) |
CL (3) | CL2013000545A1 (es) |
CO (1) | CO6680693A2 (es) |
CR (1) | CR20130126A (es) |
CY (1) | CY1118928T1 (es) |
DK (1) | DK2609118T3 (es) |
DO (1) | DOP2013000045A (es) |
EA (2) | EA031849B1 (es) |
ES (2) | ES2630328T3 (es) |
HK (1) | HK1213272A1 (es) |
HR (1) | HRP20170568T1 (es) |
HU (1) | HUE031371T2 (es) |
IL (2) | IL224886A (es) |
LT (1) | LT2609118T (es) |
ME (1) | ME02678B (es) |
MX (1) | MX339964B (es) |
MY (1) | MY171312A (es) |
NZ (3) | NZ608033A (es) |
PE (2) | PE20131403A1 (es) |
PL (1) | PL2609118T3 (es) |
PT (1) | PT2609118T (es) |
RS (1) | RS55952B1 (es) |
SG (1) | SG187945A1 (es) |
SI (1) | SI2609118T1 (es) |
WO (1) | WO2012027328A2 (es) |
ZA (1) | ZA201301442B (es) |
Families Citing this family (176)
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