OA12963A - Novel chemical compounds. - Google Patents
Novel chemical compounds. Download PDFInfo
- Publication number
- OA12963A OA12963A OA1200500154A OA1200500154A OA12963A OA 12963 A OA12963 A OA 12963A OA 1200500154 A OA1200500154 A OA 1200500154A OA 1200500154 A OA1200500154 A OA 1200500154A OA 12963 A OA12963 A OA 12963A
- Authority
- OA
- OAPI
- Prior art keywords
- ylmethylene
- thiazolidin
- phenylimino
- dihydro
- thiazol
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/426—1,3-Thiazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/08—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing alicyclic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Physical Education & Sports Medicine (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US42838402P | 2002-11-22 | 2002-11-22 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| OA12963A true OA12963A (en) | 2006-10-13 |
Family
ID=32393394
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| OA1200500154A OA12963A (en) | 2002-11-22 | 2003-11-18 | Novel chemical compounds. |
Country Status (31)
| Country | Link |
|---|---|
| US (1) | US7767701B2 (ru) |
| EP (1) | EP1567112B1 (ru) |
| JP (1) | JP2006509765A (ru) |
| KR (1) | KR20050085115A (ru) |
| CN (1) | CN100579978C (ru) |
| AP (1) | AP1967A (ru) |
| AR (1) | AR045407A1 (ru) |
| AT (1) | ATE411302T1 (ru) |
| AU (1) | AU2003298693B2 (ru) |
| BR (1) | BR0316502A (ru) |
| CA (1) | CA2507256A1 (ru) |
| CY (1) | CY1108655T1 (ru) |
| DE (1) | DE60324178D1 (ru) |
| DK (1) | DK1567112T3 (ru) |
| EA (1) | EA008865B1 (ru) |
| EC (1) | ECSP055808A (ru) |
| ES (1) | ES2315566T3 (ru) |
| HK (1) | HK1083443A1 (ru) |
| IS (1) | IS2659B (ru) |
| MA (1) | MA27701A1 (ru) |
| MX (1) | MXPA05005406A (ru) |
| MY (1) | MY140132A (ru) |
| NO (1) | NO20052928L (ru) |
| NZ (1) | NZ539873A (ru) |
| OA (1) | OA12963A (ru) |
| PL (1) | PL377564A1 (ru) |
| PT (1) | PT1567112E (ru) |
| SI (1) | SI1567112T1 (ru) |
| TW (1) | TWI309648B (ru) |
| UA (1) | UA80572C2 (ru) |
| WO (1) | WO2004047760A2 (ru) |
Families Citing this family (36)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GEP20063909B (en) | 2002-01-22 | 2006-08-25 | Warner Lambert Co | 2-(PYRIDIN-2-YLAMINO)-PYRIDO[2,3d] PYRIMIDIN-7-ONES |
| ATE412650T1 (de) * | 2003-07-11 | 2008-11-15 | Warner Lambert Co | Isethionat salz eines selektiven cdk4 inhibitors |
| CA2531140C (en) * | 2003-07-28 | 2013-06-18 | Applied Research Systems Ars Holding N.V. | 2-imino-4-(thio) oxo-5-polycyclovinylazolines for use as pi3 kinase inhibitors |
| PL1689726T3 (pl) | 2003-11-21 | 2011-05-31 | Actelion Pharmaceuticals Ltd | Pochodne 5-(benz-(z)-ylideno)tiazolidyn-4-onu jako środki immunosupresyjne |
| USRE43833E1 (en) | 2003-11-21 | 2012-11-27 | Actelion Pharmaceuticals Ltd. | Thiazolidin-4-one derivatives |
| EP1718642A4 (en) * | 2004-02-25 | 2010-11-24 | Glaxosmithkline Llc | NEW CHEMICAL COMPOUNDS |
| AR050253A1 (es) | 2004-06-24 | 2006-10-11 | Smithkline Beecham Corp | Compuesto derivado de indazol carboxamida, composicion que lo comprende y su uso para la preparacion de un medicamento |
| RU2007103709A (ru) * | 2004-07-01 | 2008-08-10 | Ф.Хоффманн-Ля Рош Аг (Ch) | Тиазолинонхинолины |
| AU2005259511A1 (en) * | 2004-07-01 | 2006-01-12 | F. Hoffmann-La Roche Ag | Quinoline thiazolinones with CDK1 antiproliferative activity |
| US7241893B2 (en) * | 2004-09-17 | 2007-07-10 | Hoffman-La Roche Inc. | Thiazolinone 2-substituted quinolines |
| US7253285B2 (en) * | 2004-09-17 | 2007-08-07 | Hoffmann-La Roche Inc. | Thiazolinone 4-monosubstituted quinolines |
| US20090042773A1 (en) * | 2004-10-12 | 2009-02-12 | Reinhard Wetzker | P13 kinase gamma inhibitors for the treatment of anaemia |
| MX2007004276A (es) | 2004-10-14 | 2007-05-16 | Hoffmann La Roche | 1,5-naftiridin-azolidinonas que tienen actividad antiproliferativa de cdk-1. |
| DE602005005211T2 (de) * | 2004-10-14 | 2009-03-19 | F. Hoffmann-La Roche Ag | Neue azaindol-thiazolinone als krebsmittel |
| EP1802614A1 (en) * | 2004-10-14 | 2007-07-04 | F. Hoffmann-Roche AG | Quinazolinylmethylenethiazolinones as cdk1 inhibitors |
| US7304074B2 (en) * | 2005-04-05 | 2007-12-04 | Hoffmann-La Roche Inc. | Substituted 1,5-naphthyridine azolinones |
| AR053602A1 (es) * | 2005-05-03 | 2007-05-09 | Smithkline Beecham Corp | Compuesto de 2- arilamino -4-oxo-1,3-tiazol-5(4h)- substituido, composicion farmaceutica que lo comprende, proceso para prepararla y uso del compuesto para preparar un medicamento |
| US20090203692A1 (en) * | 2005-05-23 | 2009-08-13 | Smithkline Beecham Corporation | Novel chemical compounds |
| WO2006133381A2 (en) * | 2005-06-08 | 2006-12-14 | Smithkline Beecham Corporation | (5z)-5-(6-quinoxalinylmethylidene)-2-[(2,4,6-trichlorophenyl)amino]-1,3-thiazol-4(5h)-one |
| TW200716580A (en) * | 2005-06-08 | 2007-05-01 | Smithkline Beecham Corp | (5Z)-5-(6-quinoxalinylmethylidene)-2-[(2,6-dichlorophenyl)amino]-1,3-thiazol-4(5H)-one |
| TW200745066A (en) | 2005-09-16 | 2007-12-16 | Torrent Pharmaceuticals Ltd | Novel PTP1B inhibitors |
| JP2009514984A (ja) * | 2005-11-08 | 2009-04-09 | スミスクライン・ビーチャム・コーポレイション | 新規化合物 |
| JP2009528386A (ja) * | 2006-03-02 | 2009-08-06 | スミスクライン・ビーチャム・コーポレイション | Ｐｉ３キナーゼ阻害剤として用いるためのチアゾロン |
| WO2007103754A2 (en) * | 2006-03-02 | 2007-09-13 | Smithkline Beecham Corporation | Thiazolones for use as pi3 kinase inhibitors |
| KR100752757B1 (ko) * | 2006-04-05 | 2007-08-29 | 한국과학기술연구원 | 2-페닐이미노-1,3-티아졸린을 포함하는 미백 조성물 |
| JP2009536622A (ja) * | 2006-04-25 | 2009-10-15 | ザ クリーブランド クリニック ファウンデーション | Ｒｎアーゼｌを活性化する抗ウイルス剤 |
| US8912340B2 (en) | 2006-11-23 | 2014-12-16 | Actelion Pharmaceuticals Ltd. | Process for the preparation of 2-imino-thiazolidin-4-one derivatives |
| EP2094676B1 (en) * | 2006-11-23 | 2013-04-10 | Actelion Pharmaceuticals Ltd. | New process for the preparation of 2-iminothiazolidin-4-one derivatives |
| US20100286041A1 (en) * | 2007-03-22 | 2010-11-11 | Smithkline Beecham Corporation | (5z)-5-(6-quinoxalinylmethylidene)-2-[(2,6-dichlorophenyl)amino]-1,3-thiazol-4(5h)-one |
| CN101274918A (zh) * | 2007-03-30 | 2008-10-01 | 中国科学院上海药物研究所 | 一类取代五元杂环化合物,其制备方法和医学用途 |
| US8119812B2 (en) | 2009-04-20 | 2012-02-21 | Sbi Biotech Co., Ltd. | Thiazolidinone derivative |
| JP5910976B2 (ja) | 2012-07-30 | 2016-04-27 | 国立大学法人京都大学 | 精神神経疾患又は悪性腫瘍に関する化合物及び医薬組成物 |
| MX350891B (es) | 2012-08-17 | 2017-09-22 | Actelion Pharmaceuticals Ltd | Proceso para la preparacion de (2z,5z)-5-(3-cloro-4-((r)-2,3-dihid roxipropoxi) bencilideno)-2-(propilimino)-3-(o-tolil) tiazolidin-4-ona y el intermediario usado en dicho proceso. |
| RU2521390C1 (ru) * | 2013-03-14 | 2014-06-27 | Общество с ограниченной ответственностью "Тиацен" | Производное роданина и средство для профилактики опухолевых заболеваний |
| HRP20220490T8 (hr) * | 2014-05-28 | 2022-06-10 | Universität Bern | Spojevi tiazolidinona i njihova upotreba u liječenju psihijatrijskih ili neuroloških poremećaja i inflamacije, posebno neuroinflamacije |
| CN104370852B (zh) * | 2014-11-26 | 2016-04-20 | 山东大学 | 一种噻唑烷酮类化合物及其在制备治疗铁紊乱相关疾病药物中的应用 |
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| SU1611216A3 (ru) * | 1986-12-29 | 1990-11-30 | Пфайзер Инк (Фирма) | Способ получени производных тиазолидиндиона или их фармацевтически приемлемых солей с щелочными металлами |
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| JPH0197926A (ja) | 1987-10-09 | 1989-04-17 | Idemitsu Kosan Co Ltd | 有機非線型光学材料 |
| DD270072A1 (de) | 1988-03-14 | 1989-07-19 | Univ Halle Wittenberg | Verfahren zur herstellung von 5-aryliden- hoch 2-thiazolin-4-onen |
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| US6452014B1 (en) | 2000-12-22 | 2002-09-17 | Geron Corporation | Telomerase inhibitors and methods of their use |
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-
2003
- 2003-11-18 OA OA1200500154A patent/OA12963A/en unknown
- 2003-11-18 NZ NZ539873A patent/NZ539873A/en not_active IP Right Cessation
- 2003-11-18 EP EP03796448A patent/EP1567112B1/en not_active Expired - Lifetime
- 2003-11-18 DK DK03796448T patent/DK1567112T3/da active
- 2003-11-18 BR BR0316502-7A patent/BR0316502A/pt not_active IP Right Cessation
- 2003-11-18 US US10/535,690 patent/US7767701B2/en not_active Expired - Fee Related
- 2003-11-18 AT AT03796448T patent/ATE411302T1/de active
- 2003-11-18 DE DE60324178T patent/DE60324178D1/de not_active Expired - Lifetime
- 2003-11-18 MX MXPA05005406A patent/MXPA05005406A/es active IP Right Grant
- 2003-11-18 PT PT03796448T patent/PT1567112E/pt unknown
- 2003-11-18 ES ES03796448T patent/ES2315566T3/es not_active Expired - Lifetime
- 2003-11-18 CN CN200380109119A patent/CN100579978C/zh not_active Expired - Fee Related
- 2003-11-18 WO PCT/US2003/037658 patent/WO2004047760A2/en active Application Filing
- 2003-11-18 JP JP2004555721A patent/JP2006509765A/ja not_active Ceased
- 2003-11-18 EA EA200500856A patent/EA008865B1/ru not_active IP Right Cessation
- 2003-11-18 AU AU2003298693A patent/AU2003298693B2/en not_active Ceased
- 2003-11-18 KR KR1020057009243A patent/KR20050085115A/ko not_active Application Discontinuation
- 2003-11-18 AP AP2005003304A patent/AP1967A/xx active
- 2003-11-18 UA UAA200504788A patent/UA80572C2/uk unknown
- 2003-11-18 PL PL377564A patent/PL377564A1/pl not_active Application Discontinuation
- 2003-11-18 CA CA002507256A patent/CA2507256A1/en not_active Abandoned
- 2003-11-18 SI SI200331463T patent/SI1567112T1/sl unknown
- 2003-11-20 AR ARP030104299A patent/AR045407A1/es not_active Application Discontinuation
- 2003-11-20 TW TW092132476A patent/TWI309648B/zh not_active IP Right Cessation
- 2003-11-20 MY MYPI20034473A patent/MY140132A/en unknown
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2005
- 2005-05-20 EC EC2005005808A patent/ECSP055808A/es unknown
- 2005-05-27 MA MA28303A patent/MA27701A1/fr unknown
- 2005-06-02 IS IS7879A patent/IS2659B/is unknown
- 2005-06-15 NO NO20052928A patent/NO20052928L/no not_active Application Discontinuation
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2006
- 2006-02-17 HK HK06102181.9A patent/HK1083443A1/xx not_active IP Right Cessation
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2008
- 2008-12-29 CY CY20081101499T patent/CY1108655T1/el unknown
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