JPS5545648A - 2-formyldibenzazepin derivative and its preparation - Google Patents

2-formyldibenzazepin derivative and its preparation

Info

Publication number
JPS5545648A
JPS5545648A JP11914178A JP11914178A JPS5545648A JP S5545648 A JPS5545648 A JP S5545648A JP 11914178 A JP11914178 A JP 11914178A JP 11914178 A JP11914178 A JP 11914178A JP S5545648 A JPS5545648 A JP S5545648A
Authority
JP
Japan
Prior art keywords
derivative
compound
formyldibenzazepin
preparation
azepin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP11914178A
Other languages
Japanese (ja)
Inventor
Yasushi Suzuki
Kunio Tsukamoto
Nobuyoshi Minami
Yukio Hasegawa
Tadaharu Watanabe
Katsuhiko Miyasaka
Takashi Kenjo
Satoshi Funakoshi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aska Pharmaceutical Co Ltd
Original Assignee
Teikoku Hormone Manufacturing Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teikoku Hormone Manufacturing Co Ltd filed Critical Teikoku Hormone Manufacturing Co Ltd
Priority to JP11914178A priority Critical patent/JPS5545648A/en
Publication of JPS5545648A publication Critical patent/JPS5545648A/en
Pending legal-status Critical Current

Links

Abstract

NEW MATERIAL:2-Formyldibenzazepin derivative of formula I (R1 is lower alkyl or aralkyl; R2 is H or halogen).
EXAMPLE: 2-Formyl-5,6-dihydro-5-methyl-11-oxodibenz[b,e]azepin.
USE: Intermediate of 5,6-dihydrodibenz[b,e]azepin-2-alkanoic acid derivative which is an analgesic anti-phlogistic agent.
PROCESS: The compound I is prepared by the Vilsmeier-Haack reaction of a compound II. i.e. by reacting the compound II with phosphorus oxyhalide, esp. phosphorus oxychloride, in excessive DMF, pref. at 90W100°C.
COPYRIGHT: (C)1980,JPO&Japio
JP11914178A 1978-09-29 1978-09-29 2-formyldibenzazepin derivative and its preparation Pending JPS5545648A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP11914178A JPS5545648A (en) 1978-09-29 1978-09-29 2-formyldibenzazepin derivative and its preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP11914178A JPS5545648A (en) 1978-09-29 1978-09-29 2-formyldibenzazepin derivative and its preparation

Publications (1)

Publication Number Publication Date
JPS5545648A true JPS5545648A (en) 1980-03-31

Family

ID=14753932

Family Applications (1)

Application Number Title Priority Date Filing Date
JP11914178A Pending JPS5545648A (en) 1978-09-29 1978-09-29 2-formyldibenzazepin derivative and its preparation

Country Status (1)

Country Link
JP (1) JPS5545648A (en)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63264921A (en) * 1987-04-07 1988-11-01 ヘルゲス、ホリングスヴォルス、ゲゼルシャフト、ミット、ベシュランクター、ハフトゥンク Fine opening and yarn polishing apparatus for fiber material
WO2004007491A1 (en) * 2002-07-10 2004-01-22 Applied Research Systems Ars Holding N.V. Azolidinone-vinyl fused-benzene derivatives
US7674792B2 (en) 2005-06-08 2010-03-09 Glaxosmithkline Llc 5(Z)-5-(6-quinoxalinylmethylidene)-2-[2,6-dichlorophenyl)amino]-1,3-thiazol-4(5H)-one
US7767701B2 (en) 2002-11-22 2010-08-03 Glaxosmithkline Llc Chemical compounds
KR101131649B1 (en) * 2002-07-10 2012-07-03 라보라토리스 세로노 에스.에이. Azolidinone-vinyl fused-benzene derivatives

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63264921A (en) * 1987-04-07 1988-11-01 ヘルゲス、ホリングスヴォルス、ゲゼルシャフト、ミット、ベシュランクター、ハフトゥンク Fine opening and yarn polishing apparatus for fiber material
WO2004007491A1 (en) * 2002-07-10 2004-01-22 Applied Research Systems Ars Holding N.V. Azolidinone-vinyl fused-benzene derivatives
JP2005538188A (en) * 2002-07-10 2005-12-15 アプライド リサーチ システムズ エーアールエス ホールディング ナームロゼ フェンノートシャップ Azolidinone-vinyl condensation-benzene derivative
EA011807B1 (en) * 2002-07-10 2009-06-30 Лаборатуар Сероно Са Azolidinone-vinyl fused-benzene derivatives
US7846925B2 (en) 2002-07-10 2010-12-07 Merck Serono Sa Azolidinone-vinyl fused-benzene derivatives
JP4782564B2 (en) * 2002-07-10 2011-09-28 メルク セローノ ソシエテ アノニム Azolidinone-vinyl condensation-benzene derivative
KR101131649B1 (en) * 2002-07-10 2012-07-03 라보라토리스 세로노 에스.에이. Azolidinone-vinyl fused-benzene derivatives
US7767701B2 (en) 2002-11-22 2010-08-03 Glaxosmithkline Llc Chemical compounds
US7674792B2 (en) 2005-06-08 2010-03-09 Glaxosmithkline Llc 5(Z)-5-(6-quinoxalinylmethylidene)-2-[2,6-dichlorophenyl)amino]-1,3-thiazol-4(5H)-one

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