PL377564A1 - Nowe związki chemiczne - Google Patents

Nowe związki chemiczne

Info

Publication number
PL377564A1
PL377564A1 PL377564A PL37756403A PL377564A1 PL 377564 A1 PL377564 A1 PL 377564A1 PL 377564 A PL377564 A PL 377564A PL 37756403 A PL37756403 A PL 37756403A PL 377564 A1 PL377564 A1 PL 377564A1
Authority
PL
Poland
Prior art keywords
chemical compounds
novel chemical
novel
compounds
chemical
Prior art date
Application number
PL377564A
Other languages
English (en)
Inventor
Masaichi Hasegawa
Jun Tang
Hideyuki Sato
Original Assignee
Smithkline Beecham Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Smithkline Beecham Corporation filed Critical Smithkline Beecham Corporation
Publication of PL377564A1 publication Critical patent/PL377564A1/pl

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • A61K31/4261,3-Thiazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06Antianaemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/08Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/08Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing alicyclic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/10Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
PL377564A 2002-11-22 2003-11-18 Nowe związki chemiczne PL377564A1 (pl)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US42838402P 2002-11-22 2002-11-22

Publications (1)

Publication Number Publication Date
PL377564A1 true PL377564A1 (pl) 2006-02-06

Family

ID=32393394

Family Applications (1)

Application Number Title Priority Date Filing Date
PL377564A PL377564A1 (pl) 2002-11-22 2003-11-18 Nowe związki chemiczne

Country Status (30)

Country Link
US (1) US7767701B2 (pl)
EP (1) EP1567112B1 (pl)
JP (1) JP2006509765A (pl)
KR (1) KR20050085115A (pl)
CN (1) CN100579978C (pl)
AP (1) AP1967A (pl)
AR (1) AR045407A1 (pl)
AT (1) ATE411302T1 (pl)
AU (1) AU2003298693B2 (pl)
BR (1) BR0316502A (pl)
CA (1) CA2507256A1 (pl)
CY (1) CY1108655T1 (pl)
DE (1) DE60324178D1 (pl)
DK (1) DK1567112T3 (pl)
EA (1) EA008865B1 (pl)
EC (1) ECSP055808A (pl)
ES (1) ES2315566T3 (pl)
IS (1) IS2659B (pl)
MA (1) MA27701A1 (pl)
MX (1) MXPA05005406A (pl)
MY (1) MY140132A (pl)
NO (1) NO20052928L (pl)
NZ (1) NZ539873A (pl)
OA (1) OA12963A (pl)
PL (1) PL377564A1 (pl)
PT (1) PT1567112E (pl)
SI (1) SI1567112T1 (pl)
TW (1) TWI309648B (pl)
UA (1) UA80572C2 (pl)
WO (1) WO2004047760A2 (pl)

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USRE43833E1 (en) 2003-11-21 2012-11-27 Actelion Pharmaceuticals Ltd. Thiazolidin-4-one derivatives
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PE20060373A1 (es) 2004-06-24 2006-04-29 Smithkline Beecham Corp Derivados 3-piperidinil-7-carboxamida-indazol como inhibidores de la actividad cinasa de ikk2
AU2005259511A1 (en) * 2004-07-01 2006-01-12 F. Hoffmann-La Roche Ag Quinoline thiazolinones with CDK1 antiproliferative activity
EP1765817A1 (en) * 2004-07-01 2007-03-28 F.Hoffmann-La Roche Ag Thiazolinone unsubstituted quinolines
US7241893B2 (en) * 2004-09-17 2007-07-10 Hoffman-La Roche Inc. Thiazolinone 2-substituted quinolines
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BRPI0517416A (pt) * 2004-10-12 2008-10-07 Serono Lab inibidores de pi3 quinase gama para o tratamento de anemia
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KR100890533B1 (ko) * 2004-10-14 2009-03-27 에프. 호프만-라 로슈 아게 Cdk1 저해제로서의 퀴나졸리닐메틸렌 티아졸리논
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TW200716132A (en) * 2005-05-03 2007-05-01 Smithkline Beecham Corp Novel chemical compounds
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JP2008543769A (ja) * 2005-06-08 2008-12-04 スミスクライン・ビーチャム・コーポレイション (5z)−5−(6−キノキサリニルメチリデン)−2−[(2,4,6−トリクロロフェニル)アミノ]−1,3−チアゾール−4(5h)−オン
TW200716580A (en) * 2005-06-08 2007-05-01 Smithkline Beecham Corp (5Z)-5-(6-quinoxalinylmethylidene)-2-[(2,6-dichlorophenyl)amino]-1,3-thiazol-4(5H)-one
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US20090023742A1 (en) * 2006-03-02 2009-01-22 Dashyant Dhanak Thiazolones for use as pi3 kinase inhibitors
KR100752757B1 (ko) * 2006-04-05 2007-08-29 한국과학기술연구원 2-페닐이미노-1,3-티아졸린을 포함하는 미백 조성물
CA2650028A1 (en) * 2006-04-25 2007-11-08 The Cleveland Clinic Foundation Anti-viral agents that activate rnase l
EP2094676B1 (en) * 2006-11-23 2013-04-10 Actelion Pharmaceuticals Ltd. New process for the preparation of 2-iminothiazolidin-4-one derivatives
US8912340B2 (en) 2006-11-23 2014-12-16 Actelion Pharmaceuticals Ltd. Process for the preparation of 2-imino-thiazolidin-4-one derivatives
US20100286041A1 (en) * 2007-03-22 2010-11-11 Smithkline Beecham Corporation (5z)-5-(6-quinoxalinylmethylidene)-2-[(2,6-dichlorophenyl)amino]-1,3-thiazol-4(5h)-one
CN101274918A (zh) * 2007-03-30 2008-10-01 中国科学院上海药物研究所 一类取代五元杂环化合物,其制备方法和医学用途
KR20120024619A (ko) 2009-04-20 2012-03-14 에스비아이 바이오테크 가부시키가이샤 티아졸리디논 유도체
CN104520303B (zh) 2012-07-30 2017-04-12 国立大学法人京都大学 关于精神神经疾病或恶性肿瘤的化合物及医药组合物
SI2885266T1 (sl) 2012-08-17 2020-10-30 Actelion Pharmaceuticals Ltd Postopek za pripravo (2Z,5Z)-5-(3-kloro-4-((R)-2,3-dihidroksipropoksi) benziliden)-2-(propilimino)-3-(O-tolil)tiazolidin-4-on in v omenjenem postopku uporabljena vmesna spojina
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Also Published As

Publication number Publication date
SI1567112T1 (sl) 2009-02-28
CN100579978C (zh) 2010-01-13
CN1742010A (zh) 2006-03-01
AP1967A (en) 2009-03-10
EP1567112B1 (en) 2008-10-15
AU2003298693A1 (en) 2004-06-18
KR20050085115A (ko) 2005-08-29
US7767701B2 (en) 2010-08-03
IS2659B (is) 2010-08-15
DE60324178D1 (de) 2008-11-27
DK1567112T3 (da) 2009-02-09
HK1083443A1 (en) 2006-07-07
EP1567112A4 (en) 2006-11-15
CA2507256A1 (en) 2004-06-10
ECSP055808A (es) 2005-09-20
UA80572C2 (en) 2007-10-10
EA008865B1 (ru) 2007-08-31
JP2006509765A (ja) 2006-03-23
NZ539873A (en) 2008-09-26
IS7879A (is) 2005-06-02
TWI309648B (en) 2009-05-11
AR045407A1 (es) 2005-10-26
AP2005003304A0 (en) 2005-06-30
MXPA05005406A (es) 2005-08-03
TW200418819A (en) 2004-10-01
OA12963A (en) 2006-10-13
WO2004047760A3 (en) 2004-10-21
MA27701A1 (fr) 2006-01-02
MY140132A (en) 2009-11-30
BR0316502A (pt) 2005-10-04
ES2315566T3 (es) 2009-04-01
NO20052928L (no) 2005-08-17
AU2003298693B2 (en) 2010-09-30
US20060293338A1 (en) 2006-12-28
CY1108655T1 (el) 2014-04-09
EP1567112A2 (en) 2005-08-31
WO2004047760A2 (en) 2004-06-10
EA200500856A1 (ru) 2005-10-27
PT1567112E (pt) 2009-01-08
NO20052928D0 (no) 2005-06-15
ATE411302T1 (de) 2008-10-15

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