OA12846A - N,N'-substituted-1,3-diamino-2-hydroxypropane derivatives. - Google Patents

N,N'-substituted-1,3-diamino-2-hydroxypropane derivatives. Download PDF

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Publication number
OA12846A
OA12846A OA1200400138A OA1200400138A OA12846A OA 12846 A OA12846 A OA 12846A OA 1200400138 A OA1200400138 A OA 1200400138A OA 1200400138 A OA1200400138 A OA 1200400138A OA 12846 A OA12846 A OA 12846A
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OA
OAPI
Prior art keywords
alkyl
phenyl
optionally substituted
alkoxy
independently
Prior art date
Application number
OA1200400138A
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English (en)
Inventor
John Varghese
Michel Maillard
Barbara Jagodzinska
James Beck
Andrea Gailunas
Larry Fang
Jennifer Sealy
Ruth Tenbrink
John Freskos
John Mickelson
Lakshman Samala
Roy Hom
Original Assignee
Elan Pharm Inc
Upjohn Co
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Publication date
Application filed by Elan Pharm Inc, Upjohn Co filed Critical Elan Pharm Inc
Publication of OA12846A publication Critical patent/OA12846A/en

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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/32—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
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    • C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
    • C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C215/22—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated
    • C07C215/28—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being unsaturated and containing six-membered aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
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OA1200400138A 2001-11-08 2002-11-08 N,N'-substituted-1,3-diamino-2-hydroxypropane derivatives. OA12846A (en)

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TW200304808A (en) 2003-10-16
EP1453789A2 (de) 2004-09-08
CA2466284A1 (en) 2003-05-15
ECSP045100A (es) 2006-06-27
GEP20074171B (en) 2007-07-25
JP2005520791A (ja) 2005-07-14
WO2003040096A2 (en) 2003-05-15
IL161881A0 (en) 2005-11-20
AU2002359376B8 (en) 2003-05-19
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RS50504A (sr) 2007-04-10
IS7255A (is) 2004-05-07
US7727997B2 (en) 2010-06-01
US7176242B2 (en) 2007-02-13
KR20050044407A (ko) 2005-05-12
EA200400648A1 (ru) 2005-04-28
BR0214035A (pt) 2005-04-26
MXPA04004428A (es) 2004-09-10
IL161881A (en) 2011-01-31
HRP20040518A2 (hr) 2007-08-31
WO2003040096A3 (en) 2004-05-06
US20040171881A1 (en) 2004-09-02
AR039555A1 (es) 2005-02-23
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