NZ630860A - Bissubstituted pyrido[4,3-d]-pyrimindin-5-one kinase nhibitors and medical uses - Google Patents

Bissubstituted pyrido[4,3-d]-pyrimindin-5-one kinase nhibitors and medical uses

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Publication number
NZ630860A
NZ630860A NZ630860A NZ63086010A NZ630860A NZ 630860 A NZ630860 A NZ 630860A NZ 630860 A NZ630860 A NZ 630860A NZ 63086010 A NZ63086010 A NZ 63086010A NZ 630860 A NZ630860 A NZ 630860A
Authority
NZ
New Zealand
Prior art keywords
disease
pyrido
bissubstituted
pyrimindin
nhibitors
Prior art date
Application number
NZ630860A
Other languages
English (en)
Inventor
Jang-Sik Choi
Ho-Juhn Song
Hong Woo Kim
Sun-Hee Lim
Youngsam Kim
Jaekyoo Lee
Jong Sung Koh
Sunhwa Chang
Hee Kyu Lee
Original Assignee
Genosco
Oscotec Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=43922599&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=NZ630860(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Genosco, Oscotec Inc filed Critical Genosco
Publication of NZ630860A publication Critical patent/NZ630860A/en

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    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
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    • C—CHEMISTRY; METALLURGY
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    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
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    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

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NZ630860A 2009-10-29 2010-10-29 Bissubstituted pyrido[4,3-d]-pyrimindin-5-one kinase nhibitors and medical uses NZ630860A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US25622209P 2009-10-29 2009-10-29
NZ599040A NZ599040A (en) 2009-10-29 2010-10-29 2,4-disubstituted pyrido[4,3-d]pyrimidin-5(6h)-one compounds for selective inhibitors of lrrk2 and syk kinases

Publications (1)

Publication Number Publication Date
NZ630860A true NZ630860A (en) 2016-03-31

Family

ID=43922599

Family Applications (2)

Application Number Title Priority Date Filing Date
NZ630860A NZ630860A (en) 2009-10-29 2010-10-29 Bissubstituted pyrido[4,3-d]-pyrimindin-5-one kinase nhibitors and medical uses
NZ599040A NZ599040A (en) 2009-10-29 2010-10-29 2,4-disubstituted pyrido[4,3-d]pyrimidin-5(6h)-one compounds for selective inhibitors of lrrk2 and syk kinases

Family Applications After (1)

Application Number Title Priority Date Filing Date
NZ599040A NZ599040A (en) 2009-10-29 2010-10-29 2,4-disubstituted pyrido[4,3-d]pyrimidin-5(6h)-one compounds for selective inhibitors of lrrk2 and syk kinases

Country Status (18)

Country Link
US (1) US8404677B2 (https=)
EP (1) EP2493313B1 (https=)
JP (1) JP5993742B2 (https=)
KR (1) KR101690358B1 (https=)
CN (1) CN102695416B (https=)
BR (1) BR112012010085B1 (https=)
CA (1) CA2779105C (https=)
CL (1) CL2012001073A1 (https=)
EA (1) EA029273B1 (https=)
ES (1) ES2658290T3 (https=)
IL (1) IL219447A (https=)
MX (1) MX2012004846A (https=)
MY (1) MY173494A (https=)
NZ (2) NZ630860A (https=)
SG (1) SG10201407012XA (https=)
TR (1) TR201802464T4 (https=)
WO (1) WO2011053861A1 (https=)
ZA (1) ZA201203842B (https=)

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WO2013125543A1 (ja) * 2012-02-20 2013-08-29 武田薬品工業株式会社 複素環化合物
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JP6437452B2 (ja) 2013-01-14 2018-12-12 インサイト・ホールディングス・コーポレイションＩｎｃｙｔｅ Ｈｏｌｄｉｎｇｓ Ｃｏｒｐｏｒａｔｉｏｎ Ｐｉｍキナーゼ阻害剤として有用な二環式芳香族カルボキサミド化合物
RS60244B1 (sr) 2013-01-15 2020-06-30 Incyte Holdings Corp Jedinjenja tiazolkarboksamida i piridinkarboksamida korisna kao inhibitori pim kinaze
CN104341437A (zh) * 2013-07-30 2015-02-11 山东亨利医药科技有限责任公司 含有双环基团的syk抑制剂
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JP6487921B2 (ja) 2013-12-17 2019-03-20 ファイザー・インク ＬＲＲＫ２阻害薬としての新規の３，４−二置換−１Ｈ−ピロロ［２，３−ｂ］ピリジンおよび４，５−二置換−７Ｈ−ピロロ［２，３−ｃ］ピリダジン
WO2015146928A1 (ja) * 2014-03-24 2015-10-01 武田薬品工業株式会社 複素環化合物
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WO2016204429A1 (ko) * 2015-06-18 2016-12-22 한국화학연구원 헤테로아릴 유도체 또는 이의 약학적으로 허용가능한 염, 이의 제조방법 및 이를 유효성분으로 포함하는 pi3 키나아제 관련 질환의 예방 또는 치료용 약학적 조성물.
BR112018000808A2 (pt) 2015-07-16 2018-09-04 Array Biopharma Inc compostos de pirazolo[1,5-a]piridina substituída como inibidores de ret cinase
TWI734699B (zh) 2015-09-09 2021-08-01 美商英塞特公司 Ｐｉｍ激酶抑制劑之鹽
KR102161364B1 (ko) 2015-09-14 2020-09-29 화이자 인코포레이티드 LRRK2 억제제로서 이미다조[4,5-c]퀴놀린 및 이미다조[4,5-c][1,5]나프티리딘 유도체
US9920032B2 (en) 2015-10-02 2018-03-20 Incyte Corporation Heterocyclic compounds useful as pim kinase inhibitors
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