NZ597375A - Tofa analogs useful in treating dermatological disorders or conditions - Google Patents
Tofa analogs useful in treating dermatological disorders or conditionsInfo
- Publication number
- NZ597375A NZ597375A NZ597375A NZ59737510A NZ597375A NZ 597375 A NZ597375 A NZ 597375A NZ 597375 A NZ597375 A NZ 597375A NZ 59737510 A NZ59737510 A NZ 59737510A NZ 597375 A NZ597375 A NZ 597375A
- Authority
- NZ
- New Zealand
- Prior art keywords
- tetradecyloxy
- furan
- conditions
- carboxylate
- dermatological disorders
- Prior art date
Links
- CZRCFAOMWRAFIC-UHFFFAOYSA-N 5-(tetradecyloxy)-2-furoic acid Chemical class CCCCCCCCCCCCCCOC1=CC=C(C(O)=O)O1 CZRCFAOMWRAFIC-UHFFFAOYSA-N 0.000 title abstract 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 2
- HWNBKQOFOQKALR-UHFFFAOYSA-N 1-[benzyl(methyl)carbamoyl]oxyethyl 5-tetradecoxyfuran-2-carboxylate Chemical compound O1C(OCCCCCCCCCCCCCC)=CC=C1C(=O)OC(C)OC(=O)N(C)CC1=CC=CC=C1 HWNBKQOFOQKALR-UHFFFAOYSA-N 0.000 abstract 1
- 208000002874 Acne Vulgaris Diseases 0.000 abstract 1
- IYYAKYDUCQWTEF-UHFFFAOYSA-N FC(COC(=O)C=1OC(=CC1)OCCCCCCCCCCCCCC)(F)F.N1(C(CCC1)C(=O)O)C(=O)OC(C)OC(=O)C=1OC(=CC1)OCCCCCCCCCCCCCC Chemical compound FC(COC(=O)C=1OC(=CC1)OCCCCCCCCCCCCCC)(F)F.N1(C(CCC1)C(=O)O)C(=O)OC(C)OC(=O)C=1OC(=CC1)OCCCCCCCCCCCCCC IYYAKYDUCQWTEF-UHFFFAOYSA-N 0.000 abstract 1
- 206010039792 Seborrhoea Diseases 0.000 abstract 1
- NRJPJMQIYLOVLO-UHFFFAOYSA-N [2-(3,4-dihydro-1h-isoquinolin-2-yl)-2-oxoethyl] 5-tetradecoxyfuran-2-carboxylate Chemical compound O1C(OCCCCCCCCCCCCCC)=CC=C1C(=O)OCC(=O)N1CC2=CC=CC=C2CC1 NRJPJMQIYLOVLO-UHFFFAOYSA-N 0.000 abstract 1
- 206010000496 acne Diseases 0.000 abstract 1
- NAROCITYINERDJ-NDEPHWFRSA-N benzyl (2s)-1-[2-(5-tetradecoxyfuran-2-carbonyl)oxyacetyl]pyrrolidine-2-carboxylate Chemical compound O1C(OCCCCCCCCCCCCCC)=CC=C1C(=O)OCC(=O)N1[C@H](C(=O)OCC=2C=CC=CC=2)CCC1 NAROCITYINERDJ-NDEPHWFRSA-N 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 208000013403 hyperactivity Diseases 0.000 abstract 1
- 230000037312 oily skin Effects 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 239000000546 pharmaceutical excipient Substances 0.000 abstract 1
- 210000001732 sebaceous gland Anatomy 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/68—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
- A61K31/341—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide not condensed with another ring, e.g. ranitidine, furosemide, bufetolol, muscarine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/351—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom not condensed with another ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/365—Lactones
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
- A61K31/4025—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil not condensed and containing further heterocyclic rings, e.g. cromakalim
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/445—Non condensed piperidines, e.g. piperocaine
- A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
- A61K31/4525—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with oxygen as a ring hetero atom
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/472—Non-condensed isoquinolines, e.g. papaverine
- A61K31/4725—Non-condensed isoquinolines, e.g. papaverine containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/08—Antiseborrheics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/14—Drugs for dermatological disorders for baldness or alopecia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/56—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/58—One oxygen atom, e.g. butenolide
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Furan Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US22404209P | 2009-07-08 | 2009-07-08 | |
| PCT/US2010/040795 WO2011005660A1 (en) | 2009-07-08 | 2010-07-01 | Tofa analogs useful in treating dermatological disorders or conditions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NZ597375A true NZ597375A (en) | 2013-08-30 |
Family
ID=43429491
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NZ597375A NZ597375A (en) | 2009-07-08 | 2010-07-01 | Tofa analogs useful in treating dermatological disorders or conditions |
Country Status (16)
| Country | Link |
|---|---|
| US (3) | US8884034B2 (enExample) |
| EP (2) | EP2451796B1 (enExample) |
| JP (1) | JP5753844B2 (enExample) |
| KR (1) | KR101722289B1 (enExample) |
| CN (2) | CN102482249B (enExample) |
| AU (1) | AU2010270797B2 (enExample) |
| BR (1) | BR112012000254A2 (enExample) |
| CA (1) | CA2766643C (enExample) |
| DK (1) | DK2451796T3 (enExample) |
| ES (2) | ES2540232T3 (enExample) |
| IL (1) | IL217421A0 (enExample) |
| MX (1) | MX2012000435A (enExample) |
| NZ (1) | NZ597375A (enExample) |
| RU (1) | RU2561729C2 (enExample) |
| SG (1) | SG176983A1 (enExample) |
| WO (1) | WO2011005660A1 (enExample) |
Families Citing this family (27)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2010270797B2 (en) * | 2009-07-08 | 2015-03-19 | Dermira (Canada), Inc. | TOFA analogs useful in treating dermatological disorders or conditions |
| US8927679B2 (en) * | 2013-01-15 | 2015-01-06 | Xerox Corporation | Tuning toner gloss with bio-based stabilizers |
| US20160220557A1 (en) | 2013-09-12 | 2016-08-04 | Pfizer Inc. | Use of acetyl-coa carboxylase inhibitors for treating acne vulgaris |
| CN107567441A (zh) * | 2015-02-05 | 2018-01-09 | 德米拉公司 | 用于制备2‑糠酸衍生物的合成方法 |
| CN107406400B (zh) | 2015-02-05 | 2020-08-04 | 德米拉公司 | 用于制备(5-十四烷氧基)呋喃-2-甲酸2-((2-乙氧基-2-氧代乙基)(甲基)氨基)-2-氧代乙酯的合成方法 |
| CA3031815A1 (en) | 2016-07-26 | 2018-02-01 | Dermira Inc. | Dermatological formulations of 2-(2-ethoxy-2-oxoethyl)(methyl)amino-2-oxoethyl 5-(tetradecyloxy)furan-2-carboxylate |
| WO2018170316A1 (en) * | 2017-03-16 | 2018-09-20 | The Board Of Trustees Of The Leland Stanford Junior University | Methods of identifying myc-driven and lipogenesis-dependent neoplasms and methods of treating the same |
| US11129818B2 (en) | 2017-06-07 | 2021-09-28 | Arcutis Biotherapeutics, Inc. | Topical roflumilast formulation having improved delivery and plasma half life |
| US9895359B1 (en) | 2017-06-07 | 2018-02-20 | Arcutis, Inc. | Inhibition of crystal growth of roflumilast |
| US12011437B1 (en) | 2017-06-07 | 2024-06-18 | Arcutis Biotherapeutics, Inc. | Roflumilast formulations with an improved pharmacokinetic profile |
| US20210161870A1 (en) | 2017-06-07 | 2021-06-03 | Arcutis Biotherapeutics, Inc. | Roflumilast formulations with an improved pharmacokinetic profile |
| CN110799187B (zh) | 2017-06-30 | 2023-10-03 | 汇科锦公司 | 螺内酯化合物 |
| WO2019072478A1 (en) | 2017-10-10 | 2019-04-18 | Galderma Research & Development | SPECIFIC ACETYL-COA CARBOXYLASE INHIBITORS FOR USE IN THE TREATMENT AND / OR PREVENTION OF ACNE |
| JP6950524B2 (ja) * | 2017-12-28 | 2021-10-13 | トヨタ自動車株式会社 | ハイブリッド車両の制御装置 |
| EP3801461A2 (en) | 2018-06-04 | 2021-04-14 | Arcutis, Inc. | Method and formulation for improving roflumilast skin penetration lag time |
| RU2678307C1 (ru) * | 2018-11-13 | 2019-01-25 | Индивидуальный предприниматель Талагаева Елена Владимировна | Активная против акне добавка к парфюмерно-косметическим продуктам |
| CN109608415B (zh) * | 2019-01-21 | 2020-12-01 | 暨南大学 | 噻唑甲酰胺类化合物及其合成和应用 |
| US20200330429A1 (en) * | 2019-04-22 | 2020-10-22 | Nestlé Skin Health Sa | Method of treating truncal acne with trifarotene |
| WO2021226370A1 (en) * | 2020-05-07 | 2021-11-11 | Arcutis Biotherapeutics, Inc. | Treatment of skin conditions using high krafft temperature anionic surfactants |
| US11707454B2 (en) | 2020-12-04 | 2023-07-25 | Arcutis Biotherapeutics, Inc. | Topical roflumilast formulation having antifungal properties |
| CN114767665B (zh) * | 2021-06-11 | 2023-10-10 | 同济大学 | 5-十四烷氧基-2-呋喃甲酸在制备用于治疗银屑病样皮炎的药物中的用途 |
| CN117881649A (zh) * | 2021-07-02 | 2024-04-12 | 安基生技新药股份有限公司 | 二甲基姜黄素的外用调配物 |
| DE102022201276A1 (de) | 2022-02-08 | 2023-08-10 | Beiersdorf Aktiengesellschaft | Neue TOFA-Analoga, Zubereitungen zur Sebumreduktion mit einem Gehalt an solchen Analoga und die kosmetische und/oder therapeutische Verwendung solcher Analoga als wirksames Prinzip zur Sebumreduktion oder -verhinderung |
| DE102022201277A1 (de) | 2022-02-08 | 2023-08-10 | Beiersdorf Aktiengesellschaft | Neue TOFA-Analoga, Zubereitungen zur Sebumreduktion mit einem Gehalt an solchen Analoga und die kosmetische und/oder therapeutische Verwendung solcher Analoga als wirksames Prinzip zur Sebumreduktion oder -verhinderung |
| WO2024058848A1 (en) | 2022-09-15 | 2024-03-21 | Arcutis Biotherapeutics, Inc. | Pharmaceutical compositions of roflumilast and solvents capable of dissolving high amounts of the drug |
| WO2025160513A1 (en) * | 2024-01-26 | 2025-07-31 | Rerx Therapeutics, Inc. | Crystalline forms of 5-(tetradecyloxy)furan-2-carboxylic acid and salts thereof |
| WO2025165758A1 (en) * | 2024-01-31 | 2025-08-07 | The Regents Of The University Of California | Combination formulations and methods for treating severe metabolic disorders or diseases |
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| CN101704700B (zh) | 2009-10-28 | 2012-04-11 | 东北师范大学 | 一种氢溴酸(溴化氢)催化芳烃的傅-克反应方法 |
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| US8920681B2 (en) | 2009-12-30 | 2014-12-30 | Korea University Research And Business Foundation | Electrically conductive polymers with enhanced conductivity |
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