NZ516535A - Use of Interleukin-18 binding protein (IL-18BP) as an inhibitor for medicaments suitable to treat tumor metastasis - Google Patents

Use of Interleukin-18 binding protein (IL-18BP) as an inhibitor for medicaments suitable to treat tumor metastasis

Info

Publication number
NZ516535A
NZ516535A NZ516535A NZ51653500A NZ516535A NZ 516535 A NZ516535 A NZ 516535A NZ 516535 A NZ516535 A NZ 516535A NZ 51653500 A NZ51653500 A NZ 51653500A NZ 516535 A NZ516535 A NZ 516535A
Authority
NZ
New Zealand
Prior art keywords
cells
hse
inhibitor
action
production
Prior art date
Application number
NZ516535A
Other languages
English (en)
Inventor
Charles Dinarello
Original Assignee
Ares Trading S
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ares Trading S filed Critical Ares Trading S
Publication of NZ516535A publication Critical patent/NZ516535A/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/07—Tetrapeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
NZ516535A 1999-07-22 2000-07-17 Use of Interleukin-18 binding protein (IL-18BP) as an inhibitor for medicaments suitable to treat tumor metastasis NZ516535A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IL13104799A IL131047A0 (en) 1999-07-22 1999-07-22 Use of il-18 inhibitors
PCT/IL2000/000419 WO2001007480A2 (en) 1999-07-22 2000-07-17 Use of interleukin-18 inhibitors to inhibit tumor metastasis

Publications (1)

Publication Number Publication Date
NZ516535A true NZ516535A (en) 2004-04-30

Family

ID=11073044

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ516535A NZ516535A (en) 1999-07-22 2000-07-17 Use of Interleukin-18 binding protein (IL-18BP) as an inhibitor for medicaments suitable to treat tumor metastasis

Country Status (31)

Country Link
US (1) US7741276B2 (en:Method)
EP (1) EP1206274B1 (en:Method)
JP (1) JP4827352B2 (en:Method)
KR (1) KR100682219B1 (en:Method)
CN (1) CN1173736C (en:Method)
AR (1) AR024907A1 (en:Method)
AT (1) ATE363288T1 (en:Method)
AU (1) AU782478B2 (en:Method)
BG (1) BG65800B1 (en:Method)
BR (1) BR0012675A (en:Method)
CA (1) CA2380216C (en:Method)
CY (1) CY1107932T1 (en:Method)
CZ (1) CZ302114B6 (en:Method)
DE (2) DE60035049T2 (en:Method)
DK (1) DK1206274T3 (en:Method)
EA (1) EA005419B1 (en:Method)
EE (1) EE04838B1 (en:Method)
ES (1) ES2186596T3 (en:Method)
HK (1) HK1048248B (en:Method)
HU (1) HU228780B1 (en:Method)
IL (2) IL131047A0 (en:Method)
MX (1) MXPA02000838A (en:Method)
NO (1) NO329827B1 (en:Method)
NZ (1) NZ516535A (en:Method)
PL (1) PL202477B1 (en:Method)
PT (1) PT1206274E (en:Method)
SK (1) SK287522B6 (en:Method)
TR (1) TR200200169T2 (en:Method)
UA (1) UA73745C2 (en:Method)
WO (1) WO2001007480A2 (en:Method)
ZA (1) ZA200200390B (en:Method)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004500086A (ja) 2000-02-10 2004-01-08 アボット・ラボラトリーズ ヒトインターロイキン１８に結合する抗体とその調整方法および使用方法
US6894155B2 (en) 2000-10-11 2005-05-17 Viron Therapeutics Nucleic acid molecules and polypeptides for immune modulation
US7718368B2 (en) 2000-12-04 2010-05-18 Viron Therapeutics Inc. Immunomodulatory protein and useful embodiments thereof
RU2225720C1 (ru) * 2002-08-12 2004-03-20 Научно-исследовательский институт онкологии Томского научного центра СО РАМН Средство, повышающее противоопухолевую и антиметастатическую активность циклофосфана
CN1909926A (zh) * 2002-10-08 2007-02-07 阿雷斯贸易股份有限公司 能够结合il－18bp和抑制第二细胞因子活性的细胞因子的用途
US7968684B2 (en) * 2003-11-12 2011-06-28 Abbott Laboratories IL-18 binding proteins
CA2609060C (en) 2005-06-03 2014-07-15 Urs Weber Production of recombinant il-18 binding protein
ATE529433T1 (de) 2005-06-10 2011-11-15 Ares Trading Sa Verfahren zur reinigung eines il-18-bindenden proteins
CL2008002153A1 (es) 2007-07-24 2009-06-05 Amgen Inc Anticuerpo aislado o fragmanto de unión de antigeno del mismo que se une al receptor de il-18 (il-18r); molecula de ácido nucleico codificante; celula huesped que la comprende; composición farmaceutica; uso médico para tratar o prevenir una condición asociada con il-18r; método in vitro para inhibir la unión de il-18 al il-18r.
US9812033B2 (en) * 2013-03-06 2017-11-07 Venkatesh R. Chari Tactile graphic display
KR20240144422A (ko) 2022-03-15 2024-10-02 컴퓨젠 엘티디. 암 치료의 단독치료법 및 병용치료법에서 il-18bp 길항제 항체 및 이의 용도
IL321948A (en) 2023-01-06 2025-09-01 Lassen Therapeutics Inc Anti-IL-18 BP antibodies
TW202515608A (zh) 2023-06-26 2025-04-16 以色列商坎布根有限公司 Ｉｌ—１８ｂｐ拮抗抗體及其於癌症治療之單一療法及組合療法的用途

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2732546B2 (ja) * 1992-09-02 1998-03-30 アイシス・ファーマシューティカルス・インコーポレーテッド 細胞接着のオリゴヌクレオチド調節
US7141393B2 (en) * 1996-12-26 2006-11-28 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo Interleukin-18-receptor proteins
SK122199A3 (en) * 1997-03-18 2000-12-11 Basf Ag Methods and compositions for modulating responsiveness to corticosteroids
IL121860A0 (en) * 1997-08-14 1998-02-22 Yeda Res & Dev Interleukin-18 binding proteins their preparation and use

Also Published As

Publication number Publication date
EP1206274B1 (en) 2007-05-30
BG106311A (en) 2002-08-30
KR100682219B1 (ko) 2007-02-12
MXPA02000838A (es) 2002-07-30
JP4827352B2 (ja) 2011-11-30
EA200200189A1 (ru) 2002-12-26
ES2186596T1 (es) 2003-05-16
DE1206274T1 (de) 2002-11-14
IL131047A0 (en) 2001-01-28
HU228780B1 (en) 2013-05-28
EA005419B1 (ru) 2005-02-24
BRPI0012675B8 (en:Method) 2021-05-25
ZA200200390B (en) 2003-04-30
PT1206274E (pt) 2007-07-06
NO20020153D0 (no) 2002-01-11
BG65800B1 (bg) 2009-12-31
US20080003216A1 (en) 2008-01-03
CZ2002195A3 (cs) 2002-06-12
CA2380216A1 (en) 2001-02-01
PL353732A1 (en) 2003-12-01
AU5843200A (en) 2001-02-13
IL147675A (en) 2009-05-04
BR0012675A (pt) 2002-04-09
HK1048248B (zh) 2005-04-22
DK1206274T3 (da) 2007-08-13
US7741276B2 (en) 2010-06-22
JP2003505472A (ja) 2003-02-12
BRPI0012675B1 (pt) 2001-02-01
HUP0202107A2 (en) 2002-10-28
DE60035049D1 (de) 2007-07-12
SK287522B6 (sk) 2011-01-04
TR200200169T2 (tr) 2002-06-21
ES2186596T3 (es) 2007-11-16
DE60035049T2 (de) 2007-09-27
CY1107932T1 (el) 2013-09-04
EP1206274A2 (en) 2002-05-22
KR20020027493A (ko) 2002-04-13
SK882002A3 (en) 2002-07-02
CN1173736C (zh) 2004-11-03
PL202477B1 (pl) 2009-06-30
AU782478B2 (en) 2005-08-04
CA2380216C (en) 2012-01-31
NO329827B1 (no) 2011-01-03
ATE363288T1 (de) 2007-06-15
EE200200032A (et) 2003-02-17
EE04838B1 (et) 2007-06-15
WO2001007480A2 (en) 2001-02-01
CN1364086A (zh) 2002-08-14
AR024907A1 (es) 2002-10-30
HK1048248A1 (en) 2003-03-28
CZ302114B6 (cs) 2010-10-20
UA73745C2 (en) 2005-09-15
NO20020153L (no) 2002-03-11
HUP0202107A3 (en) 2005-01-28
WO2001007480A3 (en) 2001-05-10

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Legal Events

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Owner name: ARES TRADING S.A. (SWITZERLAND), CH

Free format text: OLD OWNER(S): YEDA RESEARCH AND DEVELOPMENT CO. LTD.

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Effective date: 20130607

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