ZA200200390B - Use of interleukin-18 inhibitors to inhibit tumor metastasis. - Google Patents

Use of interleukin-18 inhibitors to inhibit tumor metastasis.

Info

Publication number
ZA200200390B
ZA200200390B ZA200200390A ZA200200390A ZA200200390B ZA 200200390 B ZA200200390 B ZA 200200390B ZA 200200390 A ZA200200390 A ZA 200200390A ZA 200200390 A ZA200200390 A ZA 200200390A ZA 200200390 B ZA200200390 B ZA 200200390B
Authority
ZA
South Africa
Prior art keywords
interleukin
inhibitors
tumor metastasis
inhibit tumor
inhibit
Prior art date
Application number
ZA200200390A
Other languages
English (en)
Inventor
Charles Dinarello
Original Assignee
Ares Trading Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ares Trading Sa filed Critical Ares Trading Sa
Publication of ZA200200390B publication Critical patent/ZA200200390B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/20—Interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/07—Tetrapeptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/04—Antineoplastic agents specific for metastasis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ZA200200390A 1999-07-22 2002-01-16 Use of interleukin-18 inhibitors to inhibit tumor metastasis. ZA200200390B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IL13104799A IL131047A0 (en) 1999-07-22 1999-07-22 Use of il-18 inhibitors

Publications (1)

Publication Number Publication Date
ZA200200390B true ZA200200390B (en) 2003-04-30

Family

ID=11073044

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA200200390A ZA200200390B (en) 1999-07-22 2002-01-16 Use of interleukin-18 inhibitors to inhibit tumor metastasis.

Country Status (31)

Country Link
US (1) US7741276B2 (xx)
EP (1) EP1206274B1 (xx)
JP (1) JP4827352B2 (xx)
KR (1) KR100682219B1 (xx)
CN (1) CN1173736C (xx)
AR (1) AR024907A1 (xx)
AT (1) ATE363288T1 (xx)
AU (1) AU782478B2 (xx)
BG (1) BG65800B1 (xx)
BR (1) BR0012675A (xx)
CA (1) CA2380216C (xx)
CY (1) CY1107932T1 (xx)
CZ (1) CZ302114B6 (xx)
DE (2) DE60035049T2 (xx)
DK (1) DK1206274T3 (xx)
EA (1) EA005419B1 (xx)
EE (1) EE04838B1 (xx)
ES (1) ES2186596T3 (xx)
HK (1) HK1048248B (xx)
HU (1) HU228780B1 (xx)
IL (2) IL131047A0 (xx)
MX (1) MXPA02000838A (xx)
NO (1) NO329827B1 (xx)
NZ (1) NZ516535A (xx)
PL (1) PL202477B1 (xx)
PT (1) PT1206274E (xx)
SK (1) SK287522B6 (xx)
TR (1) TR200200169T2 (xx)
UA (1) UA73745C2 (xx)
WO (1) WO2001007480A2 (xx)
ZA (1) ZA200200390B (xx)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR101111103B1 (ko) 2000-02-10 2012-02-13 아보트 러보러터리즈 사람 인터류킨-18에 결합하는 항체 및 이를 제조하고 사용하는 방법
EP1331943A4 (en) 2000-10-11 2005-01-26 Viron Therapeutics Inc NUCLEIC ACID MOLECULES AND POLYPEPTIDES FOR IMMUNOMODULATION
US7718368B2 (en) 2000-12-04 2010-05-18 Viron Therapeutics Inc. Immunomodulatory protein and useful embodiments thereof
ES2416510T3 (es) * 2002-10-08 2013-08-01 Ares Trading S.A. Uso de una citocina capaz de unirse a IL 18BP y de inhibir la actividad de una segunda citocina
US7968684B2 (en) 2003-11-12 2011-06-28 Abbott Laboratories IL-18 binding proteins
US7691611B2 (en) 2005-06-03 2010-04-06 Ares Trading S.A. Production of recombinant IL-18 binding protein
JP5091127B2 (ja) 2005-06-10 2012-12-05 アレス トレーディング ソシエテ アノニム Ｉｌ−１８結合タンパク質の精製のための方法
CL2008002153A1 (es) 2007-07-24 2009-06-05 Amgen Inc Anticuerpo aislado o fragmanto de unión de antigeno del mismo que se une al receptor de il-18 (il-18r); molecula de ácido nucleico codificante; celula huesped que la comprende; composición farmaceutica; uso médico para tratar o prevenir una condición asociada con il-18r; método in vitro para inhibir la unión de il-18 al il-18r.
US9812033B2 (en) * 2013-03-06 2017-11-07 Venkatesh R. Chari Tactile graphic display
AU2023236289A1 (en) 2022-03-15 2024-08-15 Compugen Ltd. Il-18bp antagonist antibodies and their use in monotherapy and combination therapy in the treatment of cancer

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994005333A1 (en) * 1992-09-02 1994-03-17 Isis Pharmaceuticals, Inc. Oligonucleotide modulation of cell adhesion
US7141393B2 (en) * 1996-12-26 2006-11-28 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo Interleukin-18-receptor proteins
SK122199A3 (en) * 1997-03-18 2000-12-11 Basf Ag Methods and compositions for modulating responsiveness to corticosteroids
IL121860A0 (en) * 1997-08-14 1998-02-22 Yeda Res & Dev Interleukin-18 binding proteins their preparation and use

Also Published As

Publication number Publication date
TR200200169T2 (tr) 2002-06-21
DE60035049T2 (de) 2007-09-27
IL131047A0 (en) 2001-01-28
IL147675A (en) 2009-05-04
US7741276B2 (en) 2010-06-22
KR20020027493A (ko) 2002-04-13
MXPA02000838A (es) 2002-07-30
WO2001007480A3 (en) 2001-05-10
DE60035049D1 (de) 2007-07-12
CY1107932T1 (el) 2013-09-04
JP4827352B2 (ja) 2011-11-30
EA005419B1 (ru) 2005-02-24
UA73745C2 (en) 2005-09-15
PL202477B1 (pl) 2009-06-30
CA2380216A1 (en) 2001-02-01
BRPI0012675B8 (xx) 2021-05-25
EP1206274A2 (en) 2002-05-22
HU228780B1 (en) 2013-05-28
PL353732A1 (en) 2003-12-01
HUP0202107A3 (en) 2005-01-28
WO2001007480A2 (en) 2001-02-01
JP2003505472A (ja) 2003-02-12
EA200200189A1 (ru) 2002-12-26
BRPI0012675B1 (pt) 2001-02-01
NO329827B1 (no) 2011-01-03
CA2380216C (en) 2012-01-31
BG65800B1 (bg) 2009-12-31
BG106311A (en) 2002-08-30
DE1206274T1 (de) 2002-11-14
NZ516535A (en) 2004-04-30
AU782478B2 (en) 2005-08-04
AR024907A1 (es) 2002-10-30
NO20020153L (no) 2002-03-11
CN1173736C (zh) 2004-11-03
BR0012675A (pt) 2002-04-09
KR100682219B1 (ko) 2007-02-12
CZ2002195A3 (cs) 2002-06-12
AU5843200A (en) 2001-02-13
ES2186596T3 (es) 2007-11-16
EP1206274B1 (en) 2007-05-30
CN1364086A (zh) 2002-08-14
SK882002A3 (en) 2002-07-02
EE04838B1 (et) 2007-06-15
ATE363288T1 (de) 2007-06-15
HUP0202107A2 (en) 2002-10-28
NO20020153D0 (no) 2002-01-11
PT1206274E (pt) 2007-07-06
HK1048248B (zh) 2005-04-22
DK1206274T3 (da) 2007-08-13
SK287522B6 (sk) 2011-01-04
EE200200032A (et) 2003-02-17
CZ302114B6 (cs) 2010-10-20
ES2186596T1 (es) 2003-05-16
US20080003216A1 (en) 2008-01-03
HK1048248A1 (en) 2003-03-28

Similar Documents

Publication Publication Date Title
HK1057553A1 (en) Imidazolo-5-yl-2-anilino-pyrimidines as agents forthe inhibition of the cell proliferation.
ZA200108413B (en) Use of glycosyceramide synthesis inhibitors in therapy.
GB9900416D0 (en) Inhibitors
GB9912961D0 (en) Metalloprotease inhibitors
GB0025782D0 (en) Use of inhibitors
AU4107801A (en) Alpha-amylase activity inhibitors
MXPA03000694A (es) Nuevo uso de los inhibidores de lipasa.
ZA200106197B (en) Use of glycogen phosphorlase inhibitors to inhibit tumor growth.
AU5656001A (en) Thienodibenzoazulene compounds as tumor necrosis factor inhibitors
IL145085A0 (en) Dihetero-substituted metalloprotease inhibitors
AU8323701A (en) Inhibitors of p38
AU2001236052A1 (en) Urease inhibitors
ZA200200390B (en) Use of interleukin-18 inhibitors to inhibit tumor metastasis.
AU2001285325A1 (en) Use of threo-methylphenidate compounds to enhance memory
GB0030284D0 (en) Enzyme inhibitors
GB9924522D0 (en) Enzyme inhibitors
EP1153022A4 (en) PROTEASE INHIBITORS
AU2003228450A8 (en) Inhibition of tumor growth via peroxiredoxin 3
SI1206274T1 (sl) Uporaba zaviralcev interlevkina-18 za zaviranje tumorske metastaze
AU2003299137A8 (en) Inhibition of metallo-beta-lactamase
MXPA01009617A (es) Sisntesis de propanoatos de 3-amino-3-arilo.
ZA200205471B (en) Use of IL-18 inhibitors.
GB0109278D0 (en) Enzyme inhibitors
AU2003228532A8 (en) Methods of use of the enzymes of mycothiol synthesis
GB0011100D0 (en) Small peptide amides inhibiting the proliferation of cancer cells