NO20020153L - Bruk av interleukin-18 inhibitorer for å hemme tumormetastase - Google Patents

Bruk av interleukin-18 inhibitorer for å hemme tumormetastase

Info

Publication number
NO20020153L
NO20020153L NO20020153A NO20020153A NO20020153L NO 20020153 L NO20020153 L NO 20020153L NO 20020153 A NO20020153 A NO 20020153A NO 20020153 A NO20020153 A NO 20020153A NO 20020153 L NO20020153 L NO 20020153L
Authority
NO
Norway
Prior art keywords
interleukin
inhibitors
tumor metastasis
inhibit tumor
inhibit
Prior art date
Application number
NO20020153A
Other languages
English (en)
Other versions
NO20020153D0 (no
NO329827B1 (no
Inventor
Charles Dinarello
Original Assignee
Yeda Res & Dev
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yeda Res & Dev filed Critical Yeda Res & Dev
Publication of NO20020153D0 publication Critical patent/NO20020153D0/no
Publication of NO20020153L publication Critical patent/NO20020153L/no
Publication of NO329827B1 publication Critical patent/NO329827B1/no

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19Cytokines; Lymphokines; Interferons
    • A61K38/20Interleukins [IL]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/04Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/07Tetrapeptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244Interleukins [IL]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Oncology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
NO20020153A 1999-07-22 2002-01-11 Anvendelse av inhibitorer av IL-18 produksjon og/eller dets virkning ved fremstilling av medikamenter for a hemme metastase av melanom, og anvendelse av en ekspresjonsvektor som koder for en inhibitor for IL-18 produksjon og deller dets virkning ved fremstillingen av medikamenter for a hemme metastase av melanom NO329827B1 (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IL13104799A IL131047A0 (en) 1999-07-22 1999-07-22 Use of il-18 inhibitors
PCT/IL2000/000419 WO2001007480A2 (en) 1999-07-22 2000-07-17 Use of interleukin-18 inhibitors to inhibit tumor metastasis

Publications (3)

Publication Number Publication Date
NO20020153D0 NO20020153D0 (no) 2002-01-11
NO20020153L true NO20020153L (no) 2002-03-11
NO329827B1 NO329827B1 (no) 2011-01-03

Family

ID=11073044

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20020153A NO329827B1 (no) 1999-07-22 2002-01-11 Anvendelse av inhibitorer av IL-18 produksjon og/eller dets virkning ved fremstilling av medikamenter for a hemme metastase av melanom, og anvendelse av en ekspresjonsvektor som koder for en inhibitor for IL-18 produksjon og deller dets virkning ved fremstillingen av medikamenter for a hemme metastase av melanom

Country Status (31)

Country Link
US (1) US7741276B2 (no)
EP (1) EP1206274B1 (no)
JP (1) JP4827352B2 (no)
KR (1) KR100682219B1 (no)
CN (1) CN1173736C (no)
AR (1) AR024907A1 (no)
AT (1) ATE363288T1 (no)
AU (1) AU782478B2 (no)
BG (1) BG65800B1 (no)
BR (1) BR0012675A (no)
CA (1) CA2380216C (no)
CY (1) CY1107932T1 (no)
CZ (1) CZ302114B6 (no)
DE (2) DE1206274T1 (no)
DK (1) DK1206274T3 (no)
EA (1) EA005419B1 (no)
EE (1) EE04838B1 (no)
ES (1) ES2186596T3 (no)
HK (1) HK1048248B (no)
HU (1) HU228780B1 (no)
IL (2) IL131047A0 (no)
MX (1) MXPA02000838A (no)
NO (1) NO329827B1 (no)
NZ (1) NZ516535A (no)
PL (1) PL202477B1 (no)
PT (1) PT1206274E (no)
SK (1) SK287522B6 (no)
TR (1) TR200200169T2 (no)
UA (1) UA73745C2 (no)
WO (1) WO2001007480A2 (no)
ZA (1) ZA200200390B (no)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL356836A1 (en) * 2000-02-10 2004-07-12 Abbott Laboratories Antibodies that bind human interleukin-18 and methods of making and using
JP2004528010A (ja) 2000-10-11 2004-09-16 バイロン・セラピューティックス・インコーポレーテッド 免疫モジュレーションのための核酸およびポリペプチド
US7718368B2 (en) 2000-12-04 2010-05-18 Viron Therapeutics Inc. Immunomodulatory protein and useful embodiments thereof
KR101015682B1 (ko) * 2002-10-08 2011-02-22 아레스 트레이딩 에스.에이. Il-18bp에 결합할 수 있고 제 2 사이토킨의 활성을저해할 수 있는 사이토킨의 용도
US7968684B2 (en) 2003-11-12 2011-06-28 Abbott Laboratories IL-18 binding proteins
ATE557038T1 (de) 2005-06-03 2012-05-15 Ares Trading Sa Herstellung von rekombinantem il-18 bindendem protein
ATE529433T1 (de) 2005-06-10 2011-11-15 Ares Trading Sa Verfahren zur reinigung eines il-18-bindenden proteins
CL2008002153A1 (es) 2007-07-24 2009-06-05 Amgen Inc Anticuerpo aislado o fragmanto de unión de antigeno del mismo que se une al receptor de il-18 (il-18r); molecula de ácido nucleico codificante; celula huesped que la comprende; composición farmaceutica; uso médico para tratar o prevenir una condición asociada con il-18r; método in vitro para inhibir la unión de il-18 al il-18r.
US9812033B2 (en) * 2013-03-06 2017-11-07 Venkatesh R. Chari Tactile graphic display
AU2023236289A1 (en) 2022-03-15 2024-08-15 Compugen Ltd. Il-18bp antagonist antibodies and their use in monotherapy and combination therapy in the treatment of cancer

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ256171A (en) * 1992-09-02 1996-12-20 Isis Pharmaceuticals Inc Treating diseases amenable to treatment through modulating intercellular adhesion molecule metabolism or synthesis using oligonucleotides
US7141393B2 (en) * 1996-12-26 2006-11-28 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo Interleukin-18-receptor proteins
KR20000076420A (ko) * 1997-03-18 2000-12-26 스타르크, 카르크 코르티코스테로이드에 대한 반응성을 조절하기 위한 방법 및 조성물
IL121860A0 (en) * 1997-08-14 1998-02-22 Yeda Res & Dev Interleukin-18 binding proteins their preparation and use

Also Published As

Publication number Publication date
CZ302114B6 (cs) 2010-10-20
DK1206274T3 (da) 2007-08-13
HUP0202107A3 (en) 2005-01-28
PT1206274E (pt) 2007-07-06
BR0012675A (pt) 2002-04-09
CA2380216C (en) 2012-01-31
US7741276B2 (en) 2010-06-22
AU782478B2 (en) 2005-08-04
PL353732A1 (en) 2003-12-01
NO20020153D0 (no) 2002-01-11
BG65800B1 (bg) 2009-12-31
EP1206274A2 (en) 2002-05-22
EA200200189A1 (ru) 2002-12-26
BG106311A (en) 2002-08-30
ZA200200390B (en) 2003-04-30
CN1364086A (zh) 2002-08-14
KR20020027493A (ko) 2002-04-13
DE1206274T1 (de) 2002-11-14
EE200200032A (et) 2003-02-17
WO2001007480A3 (en) 2001-05-10
AR024907A1 (es) 2002-10-30
DE60035049T2 (de) 2007-09-27
TR200200169T2 (tr) 2002-06-21
ES2186596T3 (es) 2007-11-16
HK1048248B (zh) 2005-04-22
JP2003505472A (ja) 2003-02-12
BRPI0012675B8 (no) 2021-05-25
HK1048248A1 (en) 2003-03-28
US20080003216A1 (en) 2008-01-03
CN1173736C (zh) 2004-11-03
EP1206274B1 (en) 2007-05-30
HUP0202107A2 (en) 2002-10-28
IL131047A0 (en) 2001-01-28
CA2380216A1 (en) 2001-02-01
CY1107932T1 (el) 2013-09-04
SK882002A3 (en) 2002-07-02
ES2186596T1 (es) 2003-05-16
WO2001007480A2 (en) 2001-02-01
HU228780B1 (en) 2013-05-28
ATE363288T1 (de) 2007-06-15
JP4827352B2 (ja) 2011-11-30
NO329827B1 (no) 2011-01-03
PL202477B1 (pl) 2009-06-30
BRPI0012675B1 (pt) 2001-02-01
EE04838B1 (et) 2007-06-15
MXPA02000838A (es) 2002-07-30
DE60035049D1 (de) 2007-07-12
IL147675A (en) 2009-05-04
CZ2002195A3 (cs) 2002-06-12
NZ516535A (en) 2004-04-30
SK287522B6 (sk) 2011-01-04
UA73745C2 (en) 2005-09-15
KR100682219B1 (ko) 2007-02-12
EA005419B1 (ru) 2005-02-24
AU5843200A (en) 2001-02-13

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