ATE529433T1 - Verfahren zur reinigung eines il-18-bindenden proteins - Google Patents
Verfahren zur reinigung eines il-18-bindenden proteinsInfo
- Publication number
- ATE529433T1 ATE529433T1 AT06763598T AT06763598T ATE529433T1 AT E529433 T1 ATE529433 T1 AT E529433T1 AT 06763598 T AT06763598 T AT 06763598T AT 06763598 T AT06763598 T AT 06763598T AT E529433 T1 ATE529433 T1 AT E529433T1
- Authority
- AT
- Austria
- Prior art keywords
- binding protein
- purifying
- purified
- fluid
- production
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
- C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
- B01J20/286—Phases chemically bonded to a substrate, e.g. to silica or to polymers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
- B01J20/30—Processes for preparing, regenerating, or reactivating
- B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
- B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
- B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
- B01J20/3244—Non-macromolecular compounds
- B01J20/3246—Non-macromolecular compounds having a well defined chemical structure
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
- C07K9/006—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure
- C07K9/008—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure directly attached to a hetero atom of the saccharide radical, e.g. actaplanin, avoparcin, ristomycin, vancomycin
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 - B01D15/36
- B01D15/3804—Affinity chromatography
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Analytical Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP05105124 | 2005-06-10 | ||
US69041405P | 2005-06-14 | 2005-06-14 | |
PCT/EP2006/063029 WO2006131550A1 (en) | 2005-06-10 | 2006-06-08 | Process for the purification of il-18 binding protein |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE529433T1 true ATE529433T1 (de) | 2011-11-15 |
Family
ID=34940147
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT06763598T ATE529433T1 (de) | 2005-06-10 | 2006-06-08 | Verfahren zur reinigung eines il-18-bindenden proteins |
Country Status (17)
Country | Link |
---|---|
US (1) | US8217152B2 (de) |
EP (1) | EP1891088B1 (de) |
JP (1) | JP5091127B2 (de) |
AT (1) | ATE529433T1 (de) |
AU (1) | AU2006256763B2 (de) |
CA (1) | CA2610804C (de) |
CY (1) | CY1112312T1 (de) |
DK (1) | DK1891088T3 (de) |
ES (1) | ES2375831T3 (de) |
HR (1) | HRP20110948T1 (de) |
IL (1) | IL187935A (de) |
NO (1) | NO340957B1 (de) |
PL (1) | PL1891088T3 (de) |
PT (1) | PT1891088E (de) |
RS (1) | RS52273B (de) |
SI (1) | SI1891088T1 (de) |
WO (1) | WO2006131550A1 (de) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EA010096B1 (ru) | 2003-03-11 | 2008-06-30 | Лаборатуар Сероно Са | Экспрессирующие векторы, содержащие ie2-промотор mcmv |
JP5074030B2 (ja) * | 2003-05-13 | 2012-11-14 | メルク セローノ ソシエテ アノニム | Il−18結合タンパク質の活性変異体とその医学的応用 |
WO2005040384A1 (en) | 2003-10-21 | 2005-05-06 | Applied Research Systems Ars Holding N.V. | Minimal dna sequence acting as a chromatin insulator and its use in protein expression |
ME01198B (me) * | 2003-11-05 | 2013-03-20 | Ares Trading Sa | Prečišćavanje il-18 vezujućeg proteina |
ATE375385T1 (de) | 2004-03-01 | 2007-10-15 | Ares Trading Sa | Verwendung eines serumfreien zellkulturmediums zur produktion von il-18bp in säugerzellen |
WO2006003134A1 (en) | 2004-06-29 | 2006-01-12 | Ares Trading S.A. | Process for the purification of il-18 binding protein |
GB0416699D0 (en) | 2004-07-27 | 2004-09-01 | Prometic Biosciences Ltd | Prion protein ligands and methods of use |
DK2267024T3 (da) * | 2005-06-03 | 2012-06-25 | Ares Trading Sa | Fremstilling af rekombinant II-18 bindingsprotein |
WO2006131768A2 (en) * | 2005-06-10 | 2006-12-14 | Prometic Biosciences Limited | Triazines as protein binding ligands |
JP6211931B2 (ja) * | 2011-03-09 | 2017-10-11 | セル・シグナリング・テクノロジー・インコーポレイテツド | モノクローナル抗体を作製するための方法および試薬 |
Family Cites Families (32)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4737462A (en) * | 1982-10-19 | 1988-04-12 | Cetus Corporation | Structural genes, plasmids and transformed cells for producing cysteine depleted muteins of interferon-β |
US4588585A (en) * | 1982-10-19 | 1986-05-13 | Cetus Corporation | Human recombinant cysteine depleted interferon-β muteins |
US4959314A (en) * | 1984-11-09 | 1990-09-25 | Cetus Corporation | Cysteine-depleted muteins of biologically active proteins |
US5116943A (en) * | 1985-01-18 | 1992-05-26 | Cetus Corporation | Oxidation-resistant muteins of Il-2 and other protein |
US5017691A (en) * | 1986-07-03 | 1991-05-21 | Schering Corporation | Mammalian interleukin-4 |
US4879111A (en) * | 1986-04-17 | 1989-11-07 | Cetus Corporation | Treatment of infections with lymphokines |
US4965195A (en) * | 1987-10-26 | 1990-10-23 | Immunex Corp. | Interleukin-7 |
US4904584A (en) * | 1987-12-23 | 1990-02-27 | Genetics Institute, Inc. | Site-specific homogeneous modification of polypeptides |
DE3902948A1 (de) * | 1989-02-01 | 1990-08-09 | Telefunken Fernseh & Rundfunk | Verfahren zur uebertragung eines signals |
DE69230789T3 (de) | 1991-01-18 | 2007-10-31 | Amgen Inc., Thousand Oaks | Methoden zur behandlung von durch den tumor nekrose faktor ausgelösten krankheiten |
US6117996A (en) * | 1995-09-20 | 2000-09-12 | Novo Nordisk A/S | Triazine based ligands and use thereof |
IL121860A0 (en) * | 1997-08-14 | 1998-02-22 | Yeda Res & Dev | Interleukin-18 binding proteins their preparation and use |
US7220717B2 (en) * | 1997-08-14 | 2007-05-22 | Yeda Research And Development Company Ltd. | Interleukin-18 binding proteins, their preparation and use |
GB9910807D0 (en) * | 1999-05-10 | 1999-07-07 | Prometic Biosciences Limited | Novel detoxification agents and their use |
CA2379388C (en) | 1999-07-13 | 2012-05-29 | George N. Cox, Iii | Immunoglobulin fusion proteins |
IL131047A0 (en) | 1999-07-22 | 2001-01-28 | Yeda Res & Dev | Use of il-18 inhibitors |
EP1257292B1 (de) | 2000-02-21 | 2011-04-27 | Merck Serono SA | Verwendung von il-18 inhibitoren |
UA87658C2 (uk) | 2000-05-05 | 2009-08-10 | Апплайд Резеч Системз Арс Холдинг Н.В. | Застосування il-18 як діагностичного маркера серцевої недостатності |
KR100857376B1 (ko) | 2001-01-29 | 2008-09-05 | 라보라토리스 세로노 에스.에이. | 심장 질환의 치료 및/또는 예방에 사용되는 il-18저해물질 |
MXPA03008110A (es) | 2001-03-08 | 2003-12-12 | Ares Trading Sa | Mutantes de interleucina-18, su produccion y uso. |
MXPA03010575A (es) | 2001-05-16 | 2005-03-07 | Yeda Res & Dev | Uso de inhibidores de il-08 para el tratamiento o prevencion de sepsis. |
KR20040030625A (ko) | 2001-05-25 | 2004-04-09 | 아레스 트레이딩 에스.에이. | Cns 손상을 치료하거나 예방하기 위한 il-18저해물질의 용도 |
UA78516C2 (en) | 2001-08-10 | 2007-04-10 | Applied Research Systems | Use of inhibitors of il-18 for treatment and/or prevention of hypersensitivity disorders, and in particular of delayed-type hypersensitivity |
BRPI0308663B8 (pt) | 2002-03-22 | 2021-05-25 | Applied Res Systems Ars Holding N V | uso de inibidores de il-18 para o tratamento e/ou prevenção de doenças vasculares periféricas |
EA010096B1 (ru) | 2003-03-11 | 2008-06-30 | Лаборатуар Сероно Са | Экспрессирующие векторы, содержащие ie2-промотор mcmv |
JP5074030B2 (ja) * | 2003-05-13 | 2012-11-14 | メルク セローノ ソシエテ アノニム | Il−18結合タンパク質の活性変異体とその医学的応用 |
WO2005040384A1 (en) | 2003-10-21 | 2005-05-06 | Applied Research Systems Ars Holding N.V. | Minimal dna sequence acting as a chromatin insulator and its use in protein expression |
ME01198B (me) * | 2003-11-05 | 2013-03-20 | Ares Trading Sa | Prečišćavanje il-18 vezujućeg proteina |
ATE375385T1 (de) * | 2004-03-01 | 2007-10-15 | Ares Trading Sa | Verwendung eines serumfreien zellkulturmediums zur produktion von il-18bp in säugerzellen |
WO2006003134A1 (en) | 2004-06-29 | 2006-01-12 | Ares Trading S.A. | Process for the purification of il-18 binding protein |
DK2267024T3 (da) | 2005-06-03 | 2012-06-25 | Ares Trading Sa | Fremstilling af rekombinant II-18 bindingsprotein |
WO2006131768A2 (en) * | 2005-06-10 | 2006-12-14 | Prometic Biosciences Limited | Triazines as protein binding ligands |
-
2006
- 2006-06-08 PL PL06763598T patent/PL1891088T3/pl unknown
- 2006-06-08 SI SI200631226T patent/SI1891088T1/sl unknown
- 2006-06-08 US US11/916,087 patent/US8217152B2/en active Active
- 2006-06-08 DK DK06763598.7T patent/DK1891088T3/da active
- 2006-06-08 ES ES06763598T patent/ES2375831T3/es active Active
- 2006-06-08 CA CA2610804A patent/CA2610804C/en active Active
- 2006-06-08 PT PT06763598T patent/PT1891088E/pt unknown
- 2006-06-08 WO PCT/EP2006/063029 patent/WO2006131550A1/en active Application Filing
- 2006-06-08 AT AT06763598T patent/ATE529433T1/de active
- 2006-06-08 AU AU2006256763A patent/AU2006256763B2/en active Active
- 2006-06-08 EP EP06763598A patent/EP1891088B1/de active Active
- 2006-06-08 JP JP2008515220A patent/JP5091127B2/ja active Active
- 2006-06-08 RS RS20120013A patent/RS52273B/en unknown
-
2007
- 2007-12-06 IL IL187935A patent/IL187935A/en active IP Right Grant
-
2008
- 2008-01-08 NO NO20080131A patent/NO340957B1/no unknown
-
2011
- 2011-12-17 HR HR20110948T patent/HRP20110948T1/hr unknown
-
2012
- 2012-01-18 CY CY20121100067T patent/CY1112312T1/el unknown
Also Published As
Publication number | Publication date |
---|---|
JP5091127B2 (ja) | 2012-12-05 |
CA2610804A1 (en) | 2006-12-14 |
SI1891088T1 (sl) | 2012-02-29 |
DK1891088T3 (da) | 2012-01-30 |
PL1891088T3 (pl) | 2012-03-30 |
US20080200658A1 (en) | 2008-08-21 |
IL187935A (en) | 2015-10-29 |
EP1891088B1 (de) | 2011-10-19 |
NO340957B1 (no) | 2017-07-31 |
NO20080131L (no) | 2008-03-07 |
WO2006131550A1 (en) | 2006-12-14 |
AU2006256763B2 (en) | 2012-08-02 |
RS52273B (en) | 2012-10-31 |
IL187935A0 (en) | 2008-03-20 |
US8217152B2 (en) | 2012-07-10 |
ES2375831T3 (es) | 2012-03-06 |
PT1891088E (pt) | 2011-12-19 |
EP1891088A1 (de) | 2008-02-27 |
CY1112312T1 (el) | 2015-12-09 |
HRP20110948T1 (hr) | 2012-01-31 |
AU2006256763A1 (en) | 2006-12-14 |
CA2610804C (en) | 2013-11-19 |
JP2008542432A (ja) | 2008-11-27 |
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Legal Events
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UEP | Publication of translation of european patent specification |
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