ATE529433T1 - Verfahren zur reinigung eines il-18-bindenden proteins - Google Patents

Verfahren zur reinigung eines il-18-bindenden proteins

Info

Publication number
ATE529433T1
ATE529433T1 AT06763598T AT06763598T ATE529433T1 AT E529433 T1 ATE529433 T1 AT E529433T1 AT 06763598 T AT06763598 T AT 06763598T AT 06763598 T AT06763598 T AT 06763598T AT E529433 T1 ATE529433 T1 AT E529433T1
Authority
AT
Austria
Prior art keywords
binding protein
purifying
purified
fluid
production
Prior art date
Application number
AT06763598T
Other languages
English (en)
Inventor
Strat Claire Le
Frederic Meuwly
Pierre Wenger
Pascal Valax
Gianni Baer
Henri Kornmann
Original Assignee
Ares Trading Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ares Trading Sa filed Critical Ares Trading Sa
Application granted granted Critical
Publication of ATE529433T1 publication Critical patent/ATE529433T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/281—Sorbents specially adapted for preparative, analytical or investigative chromatography
    • B01J20/286—Phases chemically bonded to a substrate, e.g. to silica or to polymers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/30—Processes for preparing, regenerating, or reactivating
    • B01J20/32—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating
    • B01J20/3231—Impregnating or coating ; Solid sorbent compositions obtained from processes involving impregnating or coating characterised by the coating or impregnating layer
    • B01J20/3242—Layers with a functional group, e.g. an affinity material, a ligand, a reactant or a complexing group
    • B01J20/3244—Non-macromolecular compounds
    • B01J20/3246—Non-macromolecular compounds having a well defined chemical structure
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
    • C07K9/006—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure
    • C07K9/008—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence being part of a ring structure directly attached to a hetero atom of the saccharide radical, e.g. actaplanin, avoparcin, ristomycin, vancomycin
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08—Selective adsorption, e.g. chromatography
    • B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 - B01D15/36
    • B01D15/3804—Affinity chromatography

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
AT06763598T 2005-06-10 2006-06-08 Verfahren zur reinigung eines il-18-bindenden proteins ATE529433T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
EP05105124 2005-06-10
US69041405P 2005-06-14 2005-06-14
PCT/EP2006/063029 WO2006131550A1 (en) 2005-06-10 2006-06-08 Process for the purification of il-18 binding protein

Publications (1)

Publication Number Publication Date
ATE529433T1 true ATE529433T1 (de) 2011-11-15

Family

ID=34940147

Family Applications (1)

Application Number Title Priority Date Filing Date
AT06763598T ATE529433T1 (de) 2005-06-10 2006-06-08 Verfahren zur reinigung eines il-18-bindenden proteins

Country Status (17)

Country Link
US (1) US8217152B2 (de)
EP (1) EP1891088B1 (de)
JP (1) JP5091127B2 (de)
AT (1) ATE529433T1 (de)
AU (1) AU2006256763B2 (de)
CA (1) CA2610804C (de)
CY (1) CY1112312T1 (de)
DK (1) DK1891088T3 (de)
ES (1) ES2375831T3 (de)
HR (1) HRP20110948T1 (de)
IL (1) IL187935A (de)
NO (1) NO340957B1 (de)
PL (1) PL1891088T3 (de)
PT (1) PT1891088E (de)
RS (1) RS52273B (de)
SI (1) SI1891088T1 (de)
WO (1) WO2006131550A1 (de)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EA010096B1 (ru) 2003-03-11 2008-06-30 Лаборатуар Сероно Са Экспрессирующие векторы, содержащие ie2-промотор mcmv
JP5074030B2 (ja) * 2003-05-13 2012-11-14 メルク セローノ ソシエテ アノニム Ｉｌ−１８結合タンパク質の活性変異体とその医学的応用
WO2005040384A1 (en) 2003-10-21 2005-05-06 Applied Research Systems Ars Holding N.V. Minimal dna sequence acting as a chromatin insulator and its use in protein expression
ME01198B (me) * 2003-11-05 2013-03-20 Ares Trading Sa Prečišćavanje il-18 vezujućeg proteina
ATE375385T1 (de) 2004-03-01 2007-10-15 Ares Trading Sa Verwendung eines serumfreien zellkulturmediums zur produktion von il-18bp in säugerzellen
WO2006003134A1 (en) 2004-06-29 2006-01-12 Ares Trading S.A. Process for the purification of il-18 binding protein
GB0416699D0 (en) 2004-07-27 2004-09-01 Prometic Biosciences Ltd Prion protein ligands and methods of use
DK2267024T3 (da) * 2005-06-03 2012-06-25 Ares Trading Sa Fremstilling af rekombinant II-18 bindingsprotein
WO2006131768A2 (en) * 2005-06-10 2006-12-14 Prometic Biosciences Limited Triazines as protein binding ligands
JP6211931B2 (ja) * 2011-03-09 2017-10-11 セル・シグナリング・テクノロジー・インコーポレイテツド モノクローナル抗体を作製するための方法および試薬

Family Cites Families (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4737462A (en) * 1982-10-19 1988-04-12 Cetus Corporation Structural genes, plasmids and transformed cells for producing cysteine depleted muteins of interferon-β
US4588585A (en) * 1982-10-19 1986-05-13 Cetus Corporation Human recombinant cysteine depleted interferon-β muteins
US4959314A (en) * 1984-11-09 1990-09-25 Cetus Corporation Cysteine-depleted muteins of biologically active proteins
US5116943A (en) * 1985-01-18 1992-05-26 Cetus Corporation Oxidation-resistant muteins of Il-2 and other protein
US5017691A (en) * 1986-07-03 1991-05-21 Schering Corporation Mammalian interleukin-4
US4879111A (en) * 1986-04-17 1989-11-07 Cetus Corporation Treatment of infections with lymphokines
US4965195A (en) * 1987-10-26 1990-10-23 Immunex Corp. Interleukin-7
US4904584A (en) * 1987-12-23 1990-02-27 Genetics Institute, Inc. Site-specific homogeneous modification of polypeptides
DE3902948A1 (de) * 1989-02-01 1990-08-09 Telefunken Fernseh & Rundfunk Verfahren zur uebertragung eines signals
DE69230789T3 (de) 1991-01-18 2007-10-31 Amgen Inc., Thousand Oaks Methoden zur behandlung von durch den tumor nekrose faktor ausgelösten krankheiten
US6117996A (en) * 1995-09-20 2000-09-12 Novo Nordisk A/S Triazine based ligands and use thereof
IL121860A0 (en) * 1997-08-14 1998-02-22 Yeda Res & Dev Interleukin-18 binding proteins their preparation and use
US7220717B2 (en) * 1997-08-14 2007-05-22 Yeda Research And Development Company Ltd. Interleukin-18 binding proteins, their preparation and use
GB9910807D0 (en) * 1999-05-10 1999-07-07 Prometic Biosciences Limited Novel detoxification agents and their use
CA2379388C (en) 1999-07-13 2012-05-29 George N. Cox, Iii Immunoglobulin fusion proteins
IL131047A0 (en) 1999-07-22 2001-01-28 Yeda Res & Dev Use of il-18 inhibitors
EP1257292B1 (de) 2000-02-21 2011-04-27 Merck Serono SA Verwendung von il-18 inhibitoren
UA87658C2 (uk) 2000-05-05 2009-08-10 Апплайд Резеч Системз Арс Холдинг Н.В. Застосування il-18 як діагностичного маркера серцевої недостатності
KR100857376B1 (ko) 2001-01-29 2008-09-05 라보라토리스 세로노 에스.에이. 심장 질환의 치료 및/또는 예방에 사용되는 ｉｌ-18저해물질
MXPA03008110A (es) 2001-03-08 2003-12-12 Ares Trading Sa Mutantes de interleucina-18, su produccion y uso.
MXPA03010575A (es) 2001-05-16 2005-03-07 Yeda Res & Dev Uso de inhibidores de il-08 para el tratamiento o prevencion de sepsis.
KR20040030625A (ko) 2001-05-25 2004-04-09 아레스 트레이딩 에스.에이. Ｃｎｓ 손상을 치료하거나 예방하기 위한 ｉｌ-18저해물질의 용도
UA78516C2 (en) 2001-08-10 2007-04-10 Applied Research Systems Use of inhibitors of il-18 for treatment and/or prevention of hypersensitivity disorders, and in particular of delayed-type hypersensitivity
BRPI0308663B8 (pt) 2002-03-22 2021-05-25 Applied Res Systems Ars Holding N V uso de inibidores de il-18 para o tratamento e/ou prevenção de doenças vasculares periféricas
EA010096B1 (ru) 2003-03-11 2008-06-30 Лаборатуар Сероно Са Экспрессирующие векторы, содержащие ie2-промотор mcmv
JP5074030B2 (ja) * 2003-05-13 2012-11-14 メルク セローノ ソシエテ アノニム Ｉｌ−１８結合タンパク質の活性変異体とその医学的応用
WO2005040384A1 (en) 2003-10-21 2005-05-06 Applied Research Systems Ars Holding N.V. Minimal dna sequence acting as a chromatin insulator and its use in protein expression
ME01198B (me) * 2003-11-05 2013-03-20 Ares Trading Sa Prečišćavanje il-18 vezujućeg proteina
ATE375385T1 (de) * 2004-03-01 2007-10-15 Ares Trading Sa Verwendung eines serumfreien zellkulturmediums zur produktion von il-18bp in säugerzellen
WO2006003134A1 (en) 2004-06-29 2006-01-12 Ares Trading S.A. Process for the purification of il-18 binding protein
DK2267024T3 (da) 2005-06-03 2012-06-25 Ares Trading Sa Fremstilling af rekombinant II-18 bindingsprotein
WO2006131768A2 (en) * 2005-06-10 2006-12-14 Prometic Biosciences Limited Triazines as protein binding ligands

Also Published As

Publication number Publication date
JP5091127B2 (ja) 2012-12-05
CA2610804A1 (en) 2006-12-14
SI1891088T1 (sl) 2012-02-29
DK1891088T3 (da) 2012-01-30
PL1891088T3 (pl) 2012-03-30
US20080200658A1 (en) 2008-08-21
IL187935A (en) 2015-10-29
EP1891088B1 (de) 2011-10-19
NO340957B1 (no) 2017-07-31
NO20080131L (no) 2008-03-07
WO2006131550A1 (en) 2006-12-14
AU2006256763B2 (en) 2012-08-02
RS52273B (en) 2012-10-31
IL187935A0 (en) 2008-03-20
US8217152B2 (en) 2012-07-10
ES2375831T3 (es) 2012-03-06
PT1891088E (pt) 2011-12-19
EP1891088A1 (de) 2008-02-27
CY1112312T1 (el) 2015-12-09
HRP20110948T1 (hr) 2012-01-31
AU2006256763A1 (en) 2006-12-14
CA2610804C (en) 2013-11-19
JP2008542432A (ja) 2008-11-27

Similar Documents

Publication Publication Date Title
ATE529433T1 (de) Verfahren zur reinigung eines il-18-bindenden proteins
ATE360647T1 (de) Verfahren zur aufreinigung von il-18-bindendem protein
ATE408616T1 (de) Verfahren zur aufreinigung von il-18-bindendem protein
DE602007009295D1 (de) Verfahren zur vorbereitenden rna-reinigung mittels hplc
WO2008087184A3 (en) Process for the purification of fc-containing proteins
EP1568710A3 (de) Reinigungsmethode für Antikörper
EA200970230A1 (ru) СПОСОБ ОЧИСТКИ Fc-СЛИТЫХ БЕЛКОВ
MX2008010669A (es) Plantas con caracteristicas mejoradas y un metodo para prepararlas.
ATE517917T1 (de) Herstellung eines rekombinanten il-18-bindenden proteins
DE602008004747D1 (de) Verfahren zur aufreinigung hydrophober proteine
EA202090262A1 (ru) Очистка белка
ATE496914T1 (de) Verfahren zur synthese von triazolen
DK1817342T3 (da) Fremgangsmåde til affinitetsrensning
DE602005019704D1 (de) Verfahren zur chromatographischen trennung
ATE525466T1 (de) Verfahren und testkit zur trennung, aufreinigung und wiedergewinnung von lang- und kurzkettigen nukleinsäuren
MY157846A (en) Process for the purification of fc-containing proteins
DE502006003285D1 (de) Verfahren zur auftrennung stereoisomerer verbindungen
DE10393819D2 (de) Verfahren zum Auffinden geeigneter chromatographiebedingungen zur Trennung biologischer Moleküle
DE602004015468D1 (de) Verfahren zur aufreinigung eines nichtimmunoglobulinproteins, das eine immunoglobulinähnliche (ig-like) domäne enthält
IL199752A0 (en) Purification of taci-fc
TW200716663A (en) Oil body-based purification of proteins
TW200722435A (en) Purification of proteins with cationic surfactant

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification

Ref document number: 1891088

Country of ref document: EP