DK2267024T3 - Fremstilling af rekombinant II-18 bindingsprotein - Google Patents

Fremstilling af rekombinant II-18 bindingsprotein

Info

Publication number
DK2267024T3
DK2267024T3 DK10184728.3T DK10184728T DK2267024T3 DK 2267024 T3 DK2267024 T3 DK 2267024T3 DK 10184728 T DK10184728 T DK 10184728T DK 2267024 T3 DK2267024 T3 DK 2267024T3
Authority
DK
Denmark
Prior art keywords
binding protein
recombinant
preparation
composition
production
Prior art date
Application number
DK10184728.3T
Other languages
English (en)
Inventor
Urs Wieber
Thierry Ziegler
Original Assignee
Ares Trading Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ares Trading Sa filed Critical Ares Trading Sa
Application granted granted Critical
Publication of DK2267024T3 publication Critical patent/DK2267024T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/06Antipsoriatics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00Drugs for skeletal disorders
    • A61P19/02Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • A61P37/06Immunosuppressants, e.g. drugs for graft rejection
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Rheumatology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Oncology (AREA)
  • Diabetes (AREA)
  • Dermatology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Communicable Diseases (AREA)
  • Vascular Medicine (AREA)
  • Transplantation (AREA)
  • Hematology (AREA)
  • Pain & Pain Management (AREA)
  • Pulmonology (AREA)
  • Urology & Nephrology (AREA)
  • Epidemiology (AREA)
DK10184728.3T 2005-06-03 2006-06-01 Fremstilling af rekombinant II-18 bindingsprotein DK2267024T3 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US68763105P 2005-06-03 2005-06-03
EP05104878 2005-06-03
EP05106429 2005-07-13
EP06763472A EP1885753B1 (en) 2005-06-03 2006-06-01 Production of recombinant Il-18 binding protein

Publications (1)

Publication Number Publication Date
DK2267024T3 true DK2267024T3 (da) 2012-06-25

Family

ID=44352415

Family Applications (2)

Application Number Title Priority Date Filing Date
DK06763472.5T DK1885753T3 (da) 2005-06-03 2006-06-01 Fremstilling af rekombinant II-18-proteiner
DK10184728.3T DK2267024T3 (da) 2005-06-03 2006-06-01 Fremstilling af rekombinant II-18 bindingsprotein

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DK06763472.5T DK1885753T3 (da) 2005-06-03 2006-06-01 Fremstilling af rekombinant II-18-proteiner

Country Status (15)

Country Link
US (2) US7691611B2 (da)
EP (2) EP1885753B1 (da)
JP (2) JP5199073B2 (da)
AT (2) ATE517917T1 (da)
AU (1) AU2006254103B2 (da)
CA (1) CA2609060C (da)
CY (2) CY1111969T1 (da)
DK (2) DK1885753T3 (da)
ES (2) ES2370417T3 (da)
IL (1) IL187838A (da)
NO (1) NO342802B1 (da)
PL (2) PL1885753T3 (da)
PT (2) PT2267024E (da)
SI (2) SI2267024T1 (da)
WO (1) WO2006128908A1 (da)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2001236807A1 (en) * 2000-02-10 2001-08-20 Abbott Laboratories Antibodies that bind human interleukin-18 and methods of making and using
AU2004219917B2 (en) * 2003-03-11 2008-01-31 Merck Serono Sa Expression vectors comprising the mCMV IE2 promoter
CA2524403C (en) * 2003-05-13 2013-07-09 Applied Research Systems Ars Holding N.V. Active variants of the il-18 binding protein and medical uses thereof
DE602004029598D1 (de) 2003-10-21 2010-11-25 Merck Serono Sa Minimale dna sequenz, die als chromatin-isolator wirkt, und deren verwendung für die protein-expression
WO2005049649A1 (en) * 2003-11-05 2005-06-02 Ares Trading S.A. Process for the purification of il-18 binding protein
US7968684B2 (en) 2003-11-12 2011-06-28 Abbott Laboratories IL-18 binding proteins
WO2005083058A1 (en) 2004-03-01 2005-09-09 Ares Trading S.A. Use of a serum-free cell culture medium for the production of il-18bp in mammalian cells
US7439336B2 (en) 2004-06-29 2008-10-21 Ares Trading S.A. Process for the purification of IL-18 binding protein
SI1891088T1 (sl) 2005-06-10 2012-02-29 Ares Trading Sa Postopek za äśiĺ äśenje il-18 vezavnega proteina
US20160145589A1 (en) 2011-06-24 2016-05-26 Green Cross Corporation Composition and formulation comprising recombinant human iduronate-2-sulfatase and preparation method thereof
KR101857380B1 (ko) * 2011-07-01 2018-05-11 암젠 인크 포유동물 세포 배양
US9150841B2 (en) 2012-06-29 2015-10-06 Shire Human Genetic Therapies, Inc. Cells for producing recombinant iduronate-2-sulfatase
KR101380740B1 (ko) 2012-06-29 2014-04-11 쉐어 휴먼 제네텍 세러피스, 인코포레이티드 이듀로네이트-2-설파타제의 정제
US20140004097A1 (en) * 2012-06-29 2014-01-02 Shire Human Genetic Therapies, Inc. Method of producing recombinant iduronate-2-sulfatase
US9217168B2 (en) 2013-03-14 2015-12-22 Momenta Pharmaceuticals, Inc. Methods of cell culture
US9677105B2 (en) * 2013-03-14 2017-06-13 Momenta Pharmaceuticals, Inc. Methods of cell culture
US8956830B2 (en) 2013-03-14 2015-02-17 Momenta Pharmaceuticals, Inc. Methods of cell culture
EP3391942A1 (en) * 2013-03-26 2018-10-24 Coherus Biosciences, Inc. Protein production method
CN115925928A (zh) * 2013-09-05 2023-04-07 Ab2生物股份有限公司 炎性疾病中的il-18结合蛋白(il-18bp)
USD759075S1 (en) * 2014-04-11 2016-06-14 Nutonian, Inc. Display screen with graphical user interface
USD759076S1 (en) * 2014-04-18 2016-06-14 Nutonian, Inc. Display screen with graphical user interface
SG11201706879UA (en) 2015-03-05 2017-09-28 Ab2 Bio Sa Il-18 binding protein (il-18bp) and antibodies in inflammatory diseases
KR101789509B1 (ko) * 2015-11-05 2017-10-26 주식회사 프로젠 재조합 인간 갑상선 자극 호르몬을 포함하는 조성물 및 상기 재조합 인간 갑상선 자극 호르몬의 생산 방법
KR102694992B1 (ko) 2017-10-16 2024-08-14 리제너론 파아마슈티컬스, 인크. 관류 바이오리액터 및 관련 사용 방법

Family Cites Families (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4737462A (en) 1982-10-19 1988-04-12 Cetus Corporation Structural genes, plasmids and transformed cells for producing cysteine depleted muteins of interferon-β
US4588585A (en) 1982-10-19 1986-05-13 Cetus Corporation Human recombinant cysteine depleted interferon-β muteins
US4959314A (en) 1984-11-09 1990-09-25 Cetus Corporation Cysteine-depleted muteins of biologically active proteins
US5116943A (en) 1985-01-18 1992-05-26 Cetus Corporation Oxidation-resistant muteins of Il-2 and other protein
US5266476A (en) 1985-06-18 1993-11-30 Yeda Research & Development Co., Ltd. Fibrous matrix for in vitro cell cultivation
US5017691A (en) 1986-07-03 1991-05-21 Schering Corporation Mammalian interleukin-4
US4879111A (en) 1986-04-17 1989-11-07 Cetus Corporation Treatment of infections with lymphokines
US4965195A (en) 1987-10-26 1990-10-23 Immunex Corp. Interleukin-7
US4904584A (en) 1987-12-23 1990-02-27 Genetics Institute, Inc. Site-specific homogeneous modification of polypeptides
AU1235692A (en) 1991-01-18 1992-08-27 Synergen, Inc. Methods for treating tumor necrosis factor mediated diseases
JP4306813B2 (ja) * 1995-09-19 2009-08-05 アスビオファーマ株式会社 動物細胞の新規培養方法
WO1997030161A1 (en) 1996-02-20 1997-08-21 Applied Research Systems Ars Holding N.V. Hybrid proteins which form heterodimers
NZ333325A (en) 1996-07-12 2000-06-23 Genentech Inc Recombinant chimeric heteromultimer adhesins comprising extracellular domains of ErbB receptors
IL121860A0 (en) * 1997-08-14 1998-02-22 Yeda Res & Dev Interleukin-18 binding proteins their preparation and use
WO2001000814A2 (en) 1999-06-25 2001-01-04 Universität Zürich Hetero-associating coiled-coil peptides and screenign method therefor
ES2317843T3 (es) 1999-07-13 2009-05-01 Bolder Biotechnology, Inc. Proteinas de fusion de eritropoyetina-inmunoglobulina.
IL131047A0 (en) 1999-07-22 2001-01-28 Yeda Res & Dev Use of il-18 inhibitors
UA74557C2 (en) * 1999-09-03 2006-01-16 Applied Research Systems A method for producing a heterologous secreted protein from chinese hamster ovaries cells grown on microcarriers
KR20020086540A (ko) 2000-02-21 2002-11-18 어플라이드 리서치 시스템스 에이알에스 홀딩 엔.브이. Il-18 저해물질의 용도
JP5122053B2 (ja) 2000-05-05 2013-01-16 メルク セロノ ソシエテ アノニム アテローム性動脈硬化症の治療および/または予防のためのil−18阻害剤の用途
IL140110A0 (en) * 2000-12-05 2002-02-10 Applied Research Systems Improvement of homogeneity and secretion of recombinant proteins in mammalian systems
ZA200305439B (en) 2001-01-29 2004-07-15 Applied Research Systems Use of IL-18 inhibitors for the treatment and/or prevention of heat disease.
EA005769B1 (ru) 2001-03-08 2005-06-30 Арес Трейдинг С.А. Мутанты интерлейкина-18, их продуцирование и применение
CN100556450C (zh) 2001-05-16 2009-11-04 耶达研究发展有限公司 Il-18抑制剂在治疗或预防脓毒症中的应用
BR0210007A (pt) 2001-05-25 2004-08-10 Ares Trading Sa Uso de inibidores de il-18 para tratamento ou prevenção de lesões do sistema nervoso central
UA78516C2 (en) 2001-08-10 2007-04-10 Applied Research Systems Use of inhibitors of il-18 for treatment and/or prevention of hypersensitivity disorders, and in particular of delayed-type hypersensitivity
ATE414556T1 (de) 2002-03-22 2008-12-15 Serono Lab Verwendung von il-18-inhibitoren zur behandlung und/oder prävention von peripheren gefässkrankheiten
CN1726283A (zh) 2002-08-14 2006-01-25 阿维迪斯公司 利用c4bp支架制备多聚体融合蛋白
WO2004033486A2 (en) 2002-10-11 2004-04-22 Zymogenetics, Inc. Production of homotrimeric fusion proteins
CN101044239B (zh) * 2002-12-23 2010-12-08 布里斯托尔-迈尔斯斯奎布公司 用于蛋白质生产的哺乳动物细胞培养方法
AU2004219917B2 (en) 2003-03-11 2008-01-31 Merck Serono Sa Expression vectors comprising the mCMV IE2 promoter
CA2524403C (en) 2003-05-13 2013-07-09 Applied Research Systems Ars Holding N.V. Active variants of the il-18 binding protein and medical uses thereof
DE602004029598D1 (de) * 2003-10-21 2010-11-25 Merck Serono Sa Minimale dna sequenz, die als chromatin-isolator wirkt, und deren verwendung für die protein-expression
WO2005049649A1 (en) * 2003-11-05 2005-06-02 Ares Trading S.A. Process for the purification of il-18 binding protein
WO2005083058A1 (en) 2004-03-01 2005-09-09 Ares Trading S.A. Use of a serum-free cell culture medium for the production of il-18bp in mammalian cells
US7439336B2 (en) * 2004-06-29 2008-10-21 Ares Trading S.A. Process for the purification of IL-18 binding protein
SI1891088T1 (sl) 2005-06-10 2012-02-29 Ares Trading Sa Postopek za äśiĺ äśenje il-18 vezavnega proteina

Also Published As

Publication number Publication date
IL187838A0 (en) 2008-03-20
SI2267024T1 (sl) 2012-09-28
EP2267024A1 (en) 2010-12-29
NO342802B1 (no) 2018-08-06
NO20076672L (no) 2008-02-22
WO2006128908A1 (en) 2006-12-07
AU2006254103B2 (en) 2012-09-06
DK1885753T3 (da) 2011-10-03
PL1885753T3 (pl) 2011-12-30
AU2006254103A1 (en) 2006-12-07
ES2385639T3 (es) 2012-07-27
ATE557038T1 (de) 2012-05-15
ES2370417T3 (es) 2011-12-15
EP1885753B1 (en) 2011-07-27
CA2609060C (en) 2014-07-15
EP1885753A1 (en) 2008-02-13
EP2267024B1 (en) 2012-05-09
PL2267024T3 (pl) 2012-10-31
JP2013048633A (ja) 2013-03-14
JP5837476B2 (ja) 2015-12-24
JP5199073B2 (ja) 2013-05-15
PT1885753E (pt) 2011-10-06
IL187838A (en) 2011-07-31
JP2008541748A (ja) 2008-11-27
SI1885753T1 (sl) 2011-12-30
CA2609060A1 (en) 2006-12-07
US7691611B2 (en) 2010-04-06
US20100137195A1 (en) 2010-06-03
CY1113056T1 (el) 2016-04-13
ATE517917T1 (de) 2011-08-15
PT2267024E (pt) 2012-06-01
US20080199913A1 (en) 2008-08-21
CY1111969T1 (el) 2015-11-04

Similar Documents

Publication Publication Date Title
DK2267024T3 (da) Fremstilling af rekombinant II-18 bindingsprotein
LTPA2019520I1 (lt) Rekombinantiniai anti-IL-23 antikūnai
HK1120052A1 (en) Process for the preparation of glycosylated interferon beta
DK3050963T3 (da) Fremgangsmåde til fremstilling af polypeptid ved regulering af arrangement
EA200700255A1 (ru) Новый карбамилированный еро и способ его получения
DK3219328T3 (da) Humane anti-il-23-antistoffer, sammensætninger, fremgangsmåder og anvendelser
ATE544763T1 (de) 5-arylisoxazoline zur bekämpfung wirbelloser schädlinge
BRPI0716680A2 (pt) "composto, multÍmero, composiÇço, mÉtodo de afetar a atividade de um alvo, complexo, processo de produÇço do composto, mÉtodo de produÇço de um extensço de aminoÁcidos consecutivos, processo de produÇço de uma extensço de aminoacidos consecutivos , processo para a produÇço de um composto , mÉtodo de produÇço de uma proteina e polipeptÍdeo"
DE602006010132D1 (de) Zwischenprodukte für die Herstellung von Trans-5-Chlor-2-Methyl-2,3,3a,12b-Tetrahydro-1h-DibenzÄ2,3:6,7ÜOxepinoÄ4,5-cÜPyrrol
WO2007136752A3 (en) Erythropoietin compositions
EP1970399A4 (en) METHOD FOR PRODUCING A POLYGLYCOLIC ACID RESIN COMPOSITION
DE602006018856D1 (de) Neue nutrazeutika-zusammensetzungen
TW200745159A (en) IL-6 binding proteins
CY1112312T1 (el) Διεργασια για τον καθαρισμο της πρωτεϊνης δεσμευσης της ιl-18
FI20030490A (fi) Menetelmä kuitukoostumuksen valmistamiseksi
IL191968A0 (en) Recombinant production of heparin binding proteins
DK1686105T3 (da) Fremgangsmåde til fremstilling af lette ildfaste sten
EP2261243A3 (en) Hemopexin-like structure as polypeptide-scaffold
DE602006009439D1 (de) Wanderbettverfahrenverfahren zur Herstellung von Phenylalkanen
DK1935981T3 (da) Fremgangsmåde til fremstilling af rekombinant protein
DK1988086T3 (da) Fremgangsmåde til opløsning af citalopram via dets (S)-berigede citalopramtartratforbindelse
BRPI0813111A2 (pt) Derivados de furanose
JP2008525507A5 (ja) 置換された4−アルコキシカルボニル−3−アミノチオフェン類の製造方法
ZA200805149B (en) Recombinant production of heparin binding proteins
EA200900484A1 (ru) Получение замещённых циклопентадиенил-флуоренильных лигандов с дифенильными мостиками