NO985666L - Medikamentkompleks - Google Patents

Medikamentkompleks

Info

Publication number
NO985666L
NO985666L NO985666A NO985666A NO985666L NO 985666 L NO985666 L NO 985666L NO 985666 A NO985666 A NO 985666A NO 985666 A NO985666 A NO 985666A NO 985666 L NO985666 L NO 985666L
Authority
NO
Norway
Prior art keywords
spacer
complex
drug complex
drug
carboxy
Prior art date
Application number
NO985666A
Other languages
English (en)
Norwegian (no)
Other versions
NO985666D0 (no
Inventor
Kazuhiro Inoue
Hiroshi Susaki
Masahiro Ikeda
Hiroshi Kuga
Eiji Kumazawa
Akiko Togo
Original Assignee
Daiichi Seiyaku Co
Drug Delivery System Inst Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Daiichi Seiyaku Co, Drug Delivery System Inst Ltd filed Critical Daiichi Seiyaku Co
Publication of NO985666D0 publication Critical patent/NO985666D0/no
Publication of NO985666L publication Critical patent/NO985666L/no

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/61Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates

Landscapes

  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
NO985666A 1996-06-06 1998-12-04 Medikamentkompleks NO985666L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP14442196 1996-06-06
PCT/JP1997/001914 WO1997046260A1 (fr) 1996-06-06 1997-06-05 Complexes medicamenteux

Publications (2)

Publication Number Publication Date
NO985666D0 NO985666D0 (no) 1998-12-04
NO985666L true NO985666L (no) 1999-02-04

Family

ID=15361795

Family Applications (1)

Application Number Title Priority Date Filing Date
NO985666A NO985666L (no) 1996-06-06 1998-12-04 Medikamentkompleks

Country Status (17)

Country Link
US (2) US6436912B1 (fr)
EP (1) EP0916348B1 (fr)
JP (1) JP4137183B2 (fr)
KR (1) KR20000016558A (fr)
CN (1) CN1227499A (fr)
AT (1) ATE273715T1 (fr)
AU (1) AU723392B2 (fr)
CA (1) CA2257245A1 (fr)
DE (1) DE69730332T2 (fr)
DK (1) DK0916348T3 (fr)
EA (1) EA001550B1 (fr)
ES (1) ES2229354T3 (fr)
ID (1) ID18298A (fr)
NO (1) NO985666L (fr)
PT (1) PT916348E (fr)
TW (1) TW527183B (fr)
WO (1) WO1997046260A1 (fr)

Families Citing this family (40)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH071238U (ja) * 1993-06-11 1995-01-10 株式会社大井製作所 ドアロック操作用のロッド連結装置
TW527183B (en) * 1996-06-06 2003-04-11 Daiichi Seiyaku Co Drug complex
TW409058B (en) 1996-06-06 2000-10-21 Daiichi Seiyaku Co Method for preparation of a drug complex
EP1080732A4 (fr) * 1998-05-22 2004-08-25 Daiichi Seiyaku Co Composites medicamenteux
MXPA01004239A (es) * 1998-10-30 2002-06-04 Daiichi Seiyaku Co Compuesto dds y metodo para la medicion del mismo.
DE60039998D1 (de) * 1999-10-15 2008-10-02 Daiichi Sankyo Co Ltd Pentacyclische taxan-verbindungen
US6677456B2 (en) 1999-10-15 2004-01-13 Daiichi Pharmaceutical Co., Ltd. Pentacyclic taxan compound
KR20030031502A (ko) * 2000-06-29 2003-04-21 다이이찌 세이야꾸 가부시기가이샤 디디에스 화합물 및 그의 제조방법
MXPA03000387A (es) 2000-07-13 2003-09-22 Daiichi Seiyaku Co Derivados de 4-fenil-piridina como antagonistas del receptor de neuroquinina-1.
US20030092608A1 (en) * 2001-08-21 2003-05-15 Takayuki Kawaguchi Pharmaceutical composition for inhibiting the metastasis or preventing the recurrence of malignant tumor
TWI313609B (en) * 2001-08-21 2009-08-21 Mitsubishi Tanabe Pharma Corp Pharmaceutical composition for inhibiting the metastasis or preventing the recurrence of malignant tumor
TW200306314A (en) * 2002-04-16 2003-11-16 Tanabe Seiyaku Co Liquid preparation comprising camptothecin derivative and pharmaceutical composition producible by lyophilizing the preparation
EP1572242B1 (fr) * 2002-12-13 2014-04-16 Immunomedics, Inc. Immunoconjugues comprenant une liaison intracellulaire clivable
DK1725249T3 (en) * 2003-11-06 2014-03-17 Seattle Genetics Inc Monomethylvaline compounds capable of conjugating to ligands.
CN101238142B (zh) * 2005-02-18 2012-11-14 国立大学法人德岛大学 含聚氧化烯链的脂质衍生物及含有该衍生物的脂质膜结构体
CN100516067C (zh) 2006-01-10 2009-07-22 上海恒瑞医药有限公司 具有抗肿瘤活性的紫杉酚衍生物
US9895449B2 (en) 2010-05-25 2018-02-20 Syndevrx, Inc. Polymer-conjugated MetAP2 inhibitors, and therapeutic methods of use thereof
CN107141410B (zh) 2010-05-25 2022-12-09 辛德弗雷克斯公司 聚合物缀合的MetAP2抑制剂及其应用的治疗方法
WO2014057687A1 (fr) 2012-10-11 2014-04-17 第一三共株式会社 Conjugué anticorps-médicament
JP6272230B2 (ja) 2012-10-19 2018-01-31 第一三共株式会社 親水性構造を含むリンカーで結合させた抗体−薬物コンジュゲート
AU2014250983B2 (en) 2013-04-10 2019-04-11 Syndevrx, Inc. MetAP2 inhibitors and methods of treating obesity
WO2015071841A1 (fr) 2013-11-12 2015-05-21 Druggability Technologies Holdings Limited Complexes de dabigatran et ses dérivés, procédé de préparation de ceux-ci et compositions pharmaceutiques contenant ceux-ci
CA2933666C (fr) 2013-12-25 2021-08-03 Sapporo Medical University Conjugue anticorps anti-trop2-medicament
KR102362920B1 (ko) 2014-01-31 2022-02-14 다이이찌 산쿄 가부시키가이샤 항-her2 항체-약물 접합체
SG11201608309PA (en) 2014-04-10 2016-11-29 Daiichi Sankyo Co Ltd Anti-her3 antibody-drug conjugate
WO2015155976A1 (fr) * 2014-04-10 2015-10-15 第一三共株式会社 Conjugué (anticorps anti-her2)-médicament
IL290959B2 (en) 2015-06-29 2023-04-01 Daiichi Sankyo Co Ltd Preparations containing antibody-drug conjugates and methods for their production
EP3386956B1 (fr) 2015-12-10 2021-07-14 Syndevrx, Inc. Dérivés de fumagillol et leurs polymorphes
WO2017123603A1 (fr) 2016-01-11 2017-07-20 Syndevrx, Inc. Traitement de tumeurs induites par un dysfonctionnement métabolique
JPWO2018066626A1 (ja) 2016-10-07 2019-07-18 第一三共株式会社 抗her2抗体−薬物コンジュゲート投与による耐性癌の治療
CN110049779A (zh) 2016-12-12 2019-07-23 第一三共株式会社 抗体-药物缀合物和免疫检查点抑制剂的组合
CA3050668C (fr) 2017-01-17 2023-08-15 Daiichi Sankyo Company, Limited Anticorps anti-gpr20 et conjugue anticorps-medicament anti-gpr20
TW202330036A (zh) 2017-05-15 2023-08-01 日商第一三共股份有限公司 抗體-藥物結合物之製造方法
KR20200041993A (ko) 2017-08-31 2020-04-22 다이이찌 산쿄 가부시키가이샤 항체-약물 콘주게이트의 개량 제조 방법
IL272964B2 (en) 2017-08-31 2024-02-01 Daiichi Sankyo Co Ltd Production method for antibody-drug conjugates
RS64379B1 (sr) 2018-05-18 2023-08-31 Glycotope Gmbh Anti-muc1 antitelo
JP2022512826A (ja) 2018-10-26 2022-02-07 シンデブルックス,インコーポレイティド MetAP2阻害剤のバイオマーカーとその応用
WO2021007435A1 (fr) 2019-07-10 2021-01-14 Cybrexa 2, Inc. Conjugués peptidiques de cytotoxines servant d'agents thérapeutiques
AU2020311925A1 (en) 2019-07-10 2022-02-03 Cybrexa 3, Inc. Peptide conjugates of microtubule-targeting agents as therapeutics
US11806405B1 (en) 2021-07-19 2023-11-07 Zeno Management, Inc. Immunoconjugates and methods

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59220197A (ja) * 1983-05-30 1984-12-11 Snow Brand Milk Prod Co Ltd 新規な含窒素多糖体およびその製造方法
JP2604930B2 (ja) 1990-12-14 1997-04-30 株式会社ディ・ディ・エス研究所 ヒアルロン酸およびコンドロイチン誘導体
ATE166361T1 (de) 1991-02-21 1998-06-15 Drug Delivery System Inst Ltd Carboxymethylmannoglukan und derivate davon
JP3359955B2 (ja) 1992-07-16 2002-12-24 第一製薬株式会社 抗腫瘍剤
PT640622E (pt) 1993-02-26 2000-11-30 Drug Delivery System Inst Ltd Derivados de polissacaridos e veiculos para farmacos
JPH0784481A (ja) 1993-06-26 1995-03-31 Ricoh Co Ltd 画像形成装置
US5811510A (en) * 1995-04-14 1998-09-22 General Hospital Corporation Biodegradable polyacetal polymers and methods for their formation and use
SG50747A1 (en) * 1995-08-02 1998-07-20 Tanabe Seiyaku Co Comptothecin derivatives
TW409058B (en) 1996-06-06 2000-10-21 Daiichi Seiyaku Co Method for preparation of a drug complex
TW527183B (en) * 1996-06-06 2003-04-11 Daiichi Seiyaku Co Drug complex
EP1080732A4 (fr) 1998-05-22 2004-08-25 Daiichi Seiyaku Co Composites medicamenteux
MXPA01004239A (es) 1998-10-30 2002-06-04 Daiichi Seiyaku Co Compuesto dds y metodo para la medicion del mismo.

Also Published As

Publication number Publication date
ES2229354T3 (es) 2005-04-16
ATE273715T1 (de) 2004-09-15
US6838450B2 (en) 2005-01-04
EA001550B1 (ru) 2001-04-23
KR20000016558A (ko) 2000-03-25
EA199900004A1 (ru) 1999-06-24
CN1227499A (zh) 1999-09-01
DK0916348T3 (da) 2004-12-06
JP4137183B2 (ja) 2008-08-20
AU2978797A (en) 1998-01-05
NO985666D0 (no) 1998-12-04
EP0916348A1 (fr) 1999-05-19
DE69730332T2 (de) 2005-09-22
PT916348E (pt) 2004-10-29
EP0916348B1 (fr) 2004-08-18
TW527183B (en) 2003-04-11
US6436912B1 (en) 2002-08-20
WO1997046260A1 (fr) 1997-12-11
DE69730332D1 (de) 2004-09-23
ID18298A (id) 1998-03-26
AU723392B2 (en) 2000-08-24
CA2257245A1 (fr) 1997-12-11
US20030171262A1 (en) 2003-09-11
EP0916348A4 (fr) 2000-11-29

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Legal Events

Date Code Title Description
FC2A Withdrawal, rejection or dismissal of laid open patent application